A citation-based method for searching scientific literature

Samir H Barghout, Aaron D Schimmer. Pharmacol Rev 2021
Times Cited: 9







List of co-cited articles
38 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer.
Teresa A Soucy, Peter G Smith, Michael A Milhollen, Allison J Berger, James M Gavin, Sharmila Adhikari, James E Brownell, Kristine E Burke, David P Cardin, Stephen Critchley,[...]. Nature 2009
55

A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment.
Marc L Hyer, Michael A Milhollen, Jeff Ciavarri, Paul Fleming, Tary Traore, Darshan Sappal, Jessica Huck, Judy Shi, James Gavin, Jim Brownell,[...]. Nat Med 2018
118
44

Substrate-assisted inhibition of ubiquitin-like protein-activating enzymes: the NEDD8 E1 inhibitor MLN4924 forms a NEDD8-AMP mimetic in situ.
James E Brownell, Michael D Sintchak, James M Gavin, Hua Liao, Frank J Bruzzese, Nancy J Bump, Teresa A Soucy, Michael A Milhollen, Xiaofeng Yang, Anne L Burkhardt,[...]. Mol Cell 2010
304
33

RING domain E3 ubiquitin ligases.
Raymond J Deshaies, Claudio A P Joazeiro. Annu Rev Biochem 2009
33

Preclinical evaluation of the selective small-molecule UBA1 inhibitor, TAK-243, in acute myeloid leukemia.
Samir H Barghout, Parasvi S Patel, Xiaoming Wang, G Wei Xu, Simon Kavanagh, Ondrej Halgas, Sara F Zarabi, Marcela Gronda, Rose Hurren, Danny V Jeyaraju,[...]. Leukemia 2019
29
33

The demographics of the ubiquitin system.
Michael J Clague, Claire Heride, Sylvie Urbé. Trends Cell Biol 2015
160
33

Inhibitors of ubiquitin-activating enzyme (E1), a new class of potential cancer therapeutics.
Yili Yang, Jirouta Kitagaki, Ren-Ming Dai, Yien Che Tsai, Kevin L Lorick, Robert L Ludwig, Shervon A Pierre, Jane P Jensen, Ilia V Davydov, Pankaj Oberoi,[...]. Cancer Res 2007
309
33


A gatekeeper residue for NEDD8-activating enzyme inhibition by MLN4924.
Julia I Toth, Li Yang, Russell Dahl, Matthew D Petroski. Cell Rep 2012
55
33

E2 enzymes: more than just middle men.
Mikaela D Stewart, Tobias Ritterhoff, Rachel E Klevit, Peter S Brzovic. Cell Res 2016
210
33

Neddylation-Independent Activities of MLN4924.
Hongmei Mao, Yi Sun. Adv Exp Med Biol 2020
9
22

MLN4924, a Protein Neddylation Inhibitor, Suppresses the Growth of Human Chondrosarcoma through Inhibiting Cell Proliferation and Inducing Endoplasmic Reticulum Stress-Related Apoptosis.
Meng-Huang Wu, Ching-Yu Lee, Tsung-Jen Huang, Kuo-Yuan Huang, Chih-Hsin Tang, Shing-Hwa Liu, Kuan-Lin Kuo, Feng-Che Kuan, Wei-Chou Lin, Chung-Sheng Shi. Int J Mol Sci 2018
15
22

Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.
Daniel C Scott, Jared T Hammill, Jaeki Min, David Y Rhee, Michele Connelly, Vladislav O Sviderskiy, Deepak Bhasin, Yizhe Chen, Su-Sien Ong, Sergio C Chai,[...]. Nat Chem Biol 2017
48
22

Neddylation E2 UBE2F Promotes the Survival of Lung Cancer Cells by Activating CRL5 to Degrade NOXA via the K11 Linkage.
Weihua Zhou, Jie Xu, Haomin Li, Ming Xu, Zhijian J Chen, Wenyi Wei, Zhenqiang Pan, Yi Sun. Clin Cancer Res 2017
54
22

Protein neddylation and its alterations in human cancers for targeted therapy.
Lisha Zhou, Wenjuan Zhang, Yi Sun, Lijun Jia. Cell Signal 2018
96
22

Targeting neddylation in cancer therapy.
Kristal Duncan, Georgia Schäfer, Akhona Vava, M Iqbal Parker, Luiz F Zerbini. Future Oncol 2012
24
22

Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation.
David M Duda, Laura A Borg, Daniel C Scott, Harold W Hunt, Michal Hammel, Brenda A Schulman. Cell 2008
536
22

Potent 5-Cyano-6-phenyl-pyrimidin-Based Derivatives Targeting DCN1-UBE2M Interaction.
Wenjuan Zhou, Liying Ma, Lina Ding, Qian Guo, Zhangxu He, Jing Yang, Hui Qiao, Lingyu Li, Jie Yang, Shimin Yu,[...]. J Med Chem 2019
18
22

E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification.
Danny T Huang, Olivier Ayrault, Harold W Hunt, Asad M Taherbhoy, David M Duda, Daniel C Scott, Laura A Borg, Geoffrey Neale, Peter J Murray, Martine F Roussel,[...]. Mol Cell 2009
180
22

Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay.
Daniel Martinez Molina, Rozbeh Jafari, Marina Ignatushchenko, Takahiro Seki, E Andreas Larsson, Chen Dan, Lekshmy Sreekumar, Yihai Cao, Pär Nordlund. Science 2013
796
22

Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation.
Daniel C Scott, David Y Rhee, David M Duda, Ian R Kelsall, Jennifer L Olszewski, Joao A Paulo, Annemieke de Jong, Huib Ovaa, Arno F Alpi, J Wade Harper,[...]. Cell 2016
94
22

Preclinical studies reveal MLN4924 is a promising new retinoblastoma therapy.
Arthur Aubry, Tao Yu, Rod Bremner. Cell Death Discov 2020
10
22

Targeting ubiquitin-activating enzyme induces ER stress-mediated apoptosis in B-cell lymphoma cells.
Scott Best, Taylor Hashiguchi, Adam Kittai, Nur Bruss, Cody Paiva, Craig Okada, Tingting Liu, Allison Berger, Alexey V Danilov. Blood Adv 2019
20
22

The ubiquitin-activating enzyme E1 as a therapeutic target for the treatment of leukemia and multiple myeloma.
G Wei Xu, Mohsin Ali, Tabitha E Wood, Derek Wong, Neil Maclean, Xiaoming Wang, Marcela Gronda, Marko Skrtic, Xiaoming Li, Rose Hurren,[...]. Blood 2010
110
22

Defining a Cancer Dependency Map.
Aviad Tsherniak, Francisca Vazquez, Phil G Montgomery, Barbara A Weir, Gregory Kryukov, Glenn S Cowley, Stanley Gill, William F Harrington, Sasha Pantel, John M Krill-Burger,[...]. Cell 2017
663
22

Dissecting the Specificity of Adenosyl Sulfamate Inhibitors Targeting the Ubiquitin-Activating Enzyme.
Mohit Misra, Maximilian Kuhn, Mark Löbel, Heeseon An, Alexander V Statsyuk, Christoph Sotriffer, Hermann Schindelin. Structure 2017
24
22

MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens.
Wei Li, Han Xu, Tengfei Xiao, Le Cong, Michael I Love, Feng Zhang, Rafael A Irizarry, Jun S Liu, Myles Brown, X Shirley Liu. Genome Biol 2014
611
22

Treatment-emergent mutations in NAEβ confer resistance to the NEDD8-activating enzyme inhibitor MLN4924.
Michael A Milhollen, Michael P Thomas, Usha Narayanan, Tary Traore, Jessica Riceberg, Benjamin S Amidon, Neil F Bence, Joseph B Bolen, James Brownell, Lawrence R Dick,[...]. Cancer Cell 2012
75
22

Probing the roles of SUMOylation in cancer cell biology by using a selective SAE inhibitor.
Xingyue He, Jessica Riceberg, Teresa Soucy, Erik Koenig, James Minissale, Melissa Gallery, Hugues Bernard, Xiaofeng Yang, Hua Liao, Claudia Rabino,[...]. Nat Chem Biol 2017
82
22

Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity.
L Meng, R Mohan, B H Kwok, M Elofsson, N Sin, C M Crews. Proc Natl Acad Sci U S A 1999
735
22

Deubiquitylases from genes to organism.
Michael J Clague, Igor Barsukov, Judy M Coulson, Han Liu, Daniel J Rigden, Sylvie Urbé. Physiol Rev 2013
270
22

The increasing complexity of the ubiquitin code.
Richard Yau, Michael Rape. Nat Cell Biol 2016
463
22


A genomic and functional inventory of deubiquitinating enzymes.
Sebastian M B Nijman, Mark P A Luna-Vargas, Arno Velds, Thijn R Brummelkamp, Annette M G Dirac, Titia K Sixma, René Bernards. Cell 2005
22

Inhibition of proteasome deubiquitinating activity as a new cancer therapy.
Pádraig D'Arcy, Slavica Brnjic, Maria Hägg Olofsson, Mårten Fryknäs, Kristina Lindsten, Michelandrea De Cesare, Paola Perego, Behnam Sadeghi, Moustapha Hassan, Rolf Larsson,[...]. Nat Med 2011
332
22

Proteasomal and Autophagic Degradation Systems.
Ivan Dikic. Annu Rev Biochem 2017
407
22

Principles of cancer therapy: oncogene and non-oncogene addiction.
Ji Luo, Nicole L Solimini, Stephen J Elledge. Cell 2009
22


Advances and challenges in protein-ligand docking.
Sheng-You Huang, Xiaoqin Zou. Int J Mol Sci 2010
180
11

Neddylation inhibitor MLN4924 suppresses growth and migration of human gastric cancer cells.
Huiyin Lan, Zaiming Tang, Hongchuan Jin, Yi Sun. Sci Rep 2016
49
11



Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics.
Eric J Bennett, John Rush, Steven P Gygi, J Wade Harper. Cell 2010
253
11

Computational methods in drug discovery.
Gregory Sliwoski, Sandeepkumar Kothiwale, Jens Meiler, Edward W Lowe. Pharmacol Rev 2013
600
11


Gossypol inhibits cullin neddylation by targeting SAG-CUL5 and RBX1-CUL1 complexes.
Qing Yu, Zhiguo Hu, Yanwen Shen, Yihan Jiang, Peichen Pan, Tingjun Hou, Zhen-Qiang Pan, Jing Huang, Yi Sun. Neoplasia 2020
8
12

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.
Ning Zheng, Brenda A Schulman, Langzhou Song, Julie J Miller, Philip D Jeffrey, Ping Wang, Claire Chu, Deanna M Koepp, Stephen J Elledge, Michele Pagano,[...]. Nature 2002
11

HTRF(R) Technology.
Mathis. J Biomol Screen 1999
86
11


Optical biosensing: Kinetics of protein A-IGG binding using biolayer interferometry.
Jo Leanna Wilson, Israel M Scott, Jonathan L McMurry. Biochem Mol Biol Educ 2010
18
11


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.