A citation-based method for searching scientific literature

Geun Taek Lee, Naoya Nagaya, Jenny Desantis, Kiran Madura, Hatem E Sabaawy, Wun-Jae Kim, Roy J Vaz, Gabriele Cruciani, Isaac Yi Kim. Mol Cancer Ther 2021
Times Cited: 10







List of co-cited articles
131 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


PROTACs: An Emerging Therapeutic Modality in Precision Medicine.
Dhanusha A Nalawansha, Craig M Crews. Cell Chem Biol 2020
58
50

Discovery of small-molecule inhibitors selectively targeting the DNA-binding domain of the human androgen receptor.
Huifang Li, Fuqiang Ban, Kush Dalal, Eric Leblanc, Kate Frewin, Dennis Ma, Hans Adomat, Paul S Rennie, Artem Cherkasov. J Med Chem 2014
65
40

Addressing Kinase-Independent Functions of Fak via PROTAC-Mediated Degradation.
Philipp M Cromm, Kusal T G Samarasinghe, John Hines, Craig M Crews. J Am Chem Soc 2018
106
40

Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead.
Daniel P Bondeson, Blake E Smith, George M Burslem, Alexandru D Buhimschi, John Hines, Saul Jaime-Figueroa, Jing Wang, Brian D Hamman, Alexey Ishchenko, Craig M Crews. Cell Chem Biol 2018
263
40

Targeted intracellular protein degradation induced by a small molecule: En route to chemical proteomics.
Ashley R Schneekloth, Mathieu Pucheault, Hyun Seop Tae, Craig M Crews. Bioorg Med Chem Lett 2008
220
40

Catalytic in vivo protein knockdown by small-molecule PROTACs.
Daniel P Bondeson, Alina Mares, Ian E D Smith, Eunhwa Ko, Sebastien Campos, Afjal H Miah, Katie E Mulholland, Natasha Routly, Dennis L Buckley, Jeffrey L Gustafson,[...]. Nat Chem Biol 2015
478
40

The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study.
George M Burslem, Blake E Smith, Ashton C Lai, Saul Jaime-Figueroa, Daniel C McQuaid, Daniel P Bondeson, Momar Toure, Hanqing Dong, Yimin Qian, Jing Wang,[...]. Cell Chem Biol 2018
205
40

A Chemoproteomic Approach to Query the Degradable Kinome Using a Multi-kinase Degrader.
Hai-Tsang Huang, Dennis Dobrovolsky, Joshiawa Paulk, Guang Yang, Ellen L Weisberg, Zainab M Doctor, Dennis L Buckley, Joong-Heui Cho, Eunhwa Ko, Jaebong Jang,[...]. Cell Chem Biol 2018
164
40

Protacs: chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation.
K M Sakamoto, K B Kim, A Kumagai, F Mercurio, C M Crews, R J Deshaies. Proc Natl Acad Sci U S A 2001
670
40

Regression of castrate-recurrent prostate cancer by a small-molecule inhibitor of the amino-terminus domain of the androgen receptor.
Raymond J Andersen, Nasrin R Mawji, Jun Wang, Gang Wang, Simon Haile, Jae-Kyung Myung, Kate Watt, Teresa Tam, Yu Chi Yang, Carmen A Bañuelos,[...]. Cancer Cell 2010
343
30

Overcoming mutation-based resistance to antiandrogens with rational drug design.
Minna D Balbas, Michael J Evans, David J Hosfield, John Wongvipat, Vivek K Arora, Philip A Watson, Yu Chen, Geoffrey L Greene, Yang Shen, Charles L Sawyers. Elife 2013
266
30

EPI-001, A Compound Active against Castration-Resistant Prostate Cancer, Targets Transactivation Unit 5 of the Androgen Receptor.
Eva De Mol, R Bryn Fenwick, Christopher T W Phang, Victor Buzón, Elzbieta Szulc, Alex de la Fuente, Albert Escobedo, Jesús García, Carlos W Bertoncini, Eva Estébanez-Perpiñá,[...]. ACS Chem Biol 2016
52
30

AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer.
Emmanuel S Antonarakis, Changxue Lu, Hao Wang, Brandon Luber, Mary Nakazawa, Jeffrey C Roeser, Yan Chen, Tabrez A Mohammad, Yidong Chen, Helen L Fedor,[...]. N Engl J Med 2014
30

Development of a second-generation antiandrogen for treatment of advanced prostate cancer.
Chris Tran, Samedy Ouk, Nicola J Clegg, Yu Chen, Philip A Watson, Vivek Arora, John Wongvipat, Peter M Smith-Jones, Dongwon Yoo, Andrew Kwon,[...]. Science 2009
30

PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer.
Kanak Raina, Jing Lu, Yimin Qian, Martha Altieri, Deborah Gordon, Ann Marie K Rossi, Jing Wang, Xin Chen, Hanqing Dong, Kam Siu,[...]. Proc Natl Acad Sci U S A 2016
338
30

Androgen receptor degradation by the proteolysis-targeting chimera ARCC-4 outperforms enzalutamide in cellular models of prostate cancer drug resistance.
Jemilat Salami, Shanique Alabi, Ryan R Willard, Nick J Vitale, Jing Wang, Hanqing Dong, Meizhong Jin, Donald P McDonnell, Andrew P Crew, Taavi K Neklesa,[...]. Commun Biol 2018
116
30

Targeted Degradation of Oncogenic KRASG12C by VHL-Recruiting PROTACs.
Michael J Bond, Ling Chu, Dhanusha A Nalawansha, Ke Li, Craig M Crews. ACS Cent Sci 2020
63
30

Structural basis of PROTAC cooperative recognition for selective protein degradation.
Morgan S Gadd, Andrea Testa, Xavier Lucas, Kwok-Ho Chan, Wenzhang Chen, Douglas J Lamont, Michael Zengerle, Alessio Ciulli. Nat Chem Biol 2017
347
30

Chemical genetic control of protein levels: selective in vivo targeted degradation.
John S Schneekloth, Fabiana N Fonseca, Michael Koldobskiy, Amit Mandal, Raymond Deshaies, Kathleen Sakamoto, Craig M Crews. J Am Chem Soc 2004
223
30

Differential PROTAC substrate specificity dictated by orientation of recruited E3 ligase.
Blake E Smith, Stephen L Wang, Saul Jaime-Figueroa, Alicia Harbin, Jing Wang, Brian D Hamman, Craig M Crews. Nat Commun 2019
144
30

Plasticity in binding confers selectivity in ligand-induced protein degradation.
Radosław P Nowak, Stephen L DeAngelo, Dennis Buckley, Zhixiang He, Katherine A Donovan, Jian An, Nozhat Safaee, Mark P Jedrychowski, Charles M Ponthier, Mette Ishoey,[...]. Nat Chem Biol 2018
165
30

DRUG DEVELOPMENT. Phthalimide conjugation as a strategy for in vivo target protein degradation.
Georg E Winter, Dennis L Buckley, Joshiawa Paulk, Justin M Roberts, Amanda Souza, Sirano Dhe-Paganon, James E Bradner. Science 2015
709
30

Identification and Characterization of Von Hippel-Lindau-Recruiting Proteolysis Targeting Chimeras (PROTACs) of TANK-Binding Kinase 1.
Andrew P Crew, Kanak Raina, Hanqing Dong, Yimin Qian, Jing Wang, Dominico Vigil, Yevgeniy V Serebrenik, Brian D Hamman, Alicia Morgan, Caterina Ferraro,[...]. J Med Chem 2018
114
30


Targeted protein degradation: expanding the toolbox.
Matthieu Schapira, Matthew F Calabrese, Alex N Bullock, Craig M Crews. Nat Rev Drug Discov 2019
209
30

Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4.
Michael Zengerle, Kwok-Ho Chan, Alessio Ciulli. ACS Chem Biol 2015
400
30

Functional TRIM24 degrader via conjugation of ineffectual bromodomain and VHL ligands.
Lara N Gechijian, Dennis L Buckley, Matthew A Lawlor, Jaime M Reyes, Joshiawa Paulk, Christopher J Ott, Georg E Winter, Michael A Erb, Thomas G Scott, Mousheng Xu,[...]. Nat Chem Biol 2018
104
30

A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo.
Longchuan Bai, Haibin Zhou, Renqi Xu, Yujun Zhao, Krishnapriya Chinnaswamy, Donna McEachern, Jianyong Chen, Chao-Yie Yang, Zhaomin Liu, Mi Wang,[...]. Cancer Cell 2019
129
30

Targeting the von Hippel-Lindau E3 ubiquitin ligase using small molecules to disrupt the VHL/HIF-1α interaction.
Dennis L Buckley, Inge Van Molle, Peter C Gareiss, Hyun Seop Tae, Julien Michel, Devin J Noblin, William L Jorgensen, Alessio Ciulli, Craig M Crews. J Am Chem Soc 2012
215
30

Targeting the C481S Ibrutinib-Resistance Mutation in Bruton's Tyrosine Kinase Using PROTAC-Mediated Degradation.
Alexandru D Buhimschi, Haley A Armstrong, Momar Toure, Saul Jaime-Figueroa, Timothy L Chen, Amy M Lehman, Jennifer A Woyach, Amy J Johnson, John C Byrd, Craig M Crews. Biochemistry 2018
126
30


Discovery of ERD-308 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Estrogen Receptor (ER).
Jiantao Hu, Biao Hu, Mingliang Wang, Fuming Xu, Bukeyan Miao, Chao-Yie Yang, Mi Wang, Zhaomin Liu, Daniel F Hayes, Krishnapriya Chinnaswamy,[...]. J Med Chem 2019
77
30

Discovery of an orally active VHL-recruiting PROTAC that achieves robust HMGCR degradation and potent hypolipidemic activity in vivo.
Guoshun Luo, Zhenbang Li, Xin Lin, Xinyu Li, Yu Chen, Kun Xi, Maoxu Xiao, Hanlin Wei, Lizhe Zhu, Hua Xiang. Acta Pharm Sin B 2021
6
50

An androgen receptor N-terminal domain antagonist for treating prostate cancer.
Jae-Kyung Myung, Carmen A Banuelos, Javier Garcia Fernandez, Nasrin R Mawji, Jun Wang, Amy H Tien, Yu Chi Yang, Iran Tavakoli, Simon Haile, Kate Watt,[...]. J Clin Invest 2013
183
20

Role of the HSP90-associated cochaperone p23 in enhancing activity of the androgen receptor and significance for prostate cancer.
Vikash Reebye, Laia Querol Cano, Derek N Lavery, Greg N Brooke, Sue M Powell, Deepa Chotai, Marjorie M Walker, Hayley C Whitaker, Robin Wait, Helen C Hurst,[...]. Mol Endocrinol 2012
26
20

Nonmetastatic, Castration-Resistant Prostate Cancer and Survival with Darolutamide.
Karim Fizazi, Neal Shore, Teuvo L Tammela, Albertas Ulys, Egils Vjaters, Sergey Polyakov, Mindaugas Jievaltas, Murilo Luz, Boris Alekseev, Iris Kuss,[...]. N Engl J Med 2020
54
20

Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands.
Norihito Shibata, Katsunori Nagai, Yoko Morita, Osamu Ujikawa, Nobumichi Ohoka, Takayuki Hattori, Ryokichi Koyama, Osamu Sano, Yasuhiro Imaeda, Hiroshi Nara,[...]. J Med Chem 2018
77
20

Targeting steroid hormone receptors for ubiquitination and degradation in breast and prostate cancer.
A Rodriguez-Gonzalez, K Cyrus, M Salcius, K Kim, C M Crews, R J Deshaies, K M Sakamoto. Oncogene 2008
104
20

Novel Selective Agents for the Degradation of Androgen Receptor Variants to Treat Castration-Resistant Prostate Cancer.
Suriyan Ponnusamy, Christopher C Coss, Thirumagal Thiyagarajan, Kate Watts, Dong-Jin Hwang, Yali He, Luke A Selth, Iain J McEwan, Charles B Duke, Jayaprakash Pagadala,[...]. Cancer Res 2017
28
20

The androgen receptor gene mutations database: 2012 update.
Bruce Gottlieb, Lenore K Beitel, Abbesha Nadarajah, Miltiadis Paliouras, Mark Trifiro. Hum Mutat 2012
264
20

Targeting Binding Function-3 of the Androgen Receptor Blocks Its Co-Chaperone Interactions, Nuclear Translocation, and Activation.
Nada Lallous, Eric Leblanc, Ravi S N Munuganti, Mohamed D H Hassona, Nader Al Nakouzi, Shannon Awrey, Helene Morin, Mani Roshan-Moniri, Kriti Singh, Sam Lawn,[...]. Mol Cancer Ther 2016
17
20

Targeting the binding function 3 (BF3) site of the human androgen receptor through virtual screening.
Nathan A Lack, Peter Axerio-Cilies, Peyman Tavassoli, Frank Q Han, Ka Hong Chan, Clementine Feau, Eric LeBlanc, Emma Tomlinson Guns, R Kiplin Guy, Paul S Rennie,[...]. J Med Chem 2011
80
20

Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer.
Irfan A Asangani, Vijaya L Dommeti, Xiaoju Wang, Rohit Malik, Marcin Cieslik, Rendong Yang, June Escara-Wilke, Kari Wilder-Romans, Sudheer Dhanireddy, Carl Engelke,[...]. Nature 2014
581
20

Discovery of ARD-69 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor (AR) for the Treatment of Prostate Cancer.
Xin Han, Chao Wang, Chong Qin, Weiguo Xiang, Ester Fernandez-Salas, Chao-Yie Yang, Mi Wang, Lijie Zhao, Tianfeng Xu, Krishnapriya Chinnaswamy,[...]. J Med Chem 2019
115
20

Harnessing the anti-cancer natural product nimbolide for targeted protein degradation.
Jessica N Spradlin, Xirui Hu, Carl C Ward, Scott M Brittain, Michael D Jones, Lisha Ou, Milton To, Andrew Proudfoot, Elizabeth Ornelas, Mikias Woldegiorgis,[...]. Nat Chem Biol 2019
108
20

Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16.
Xiaoyu Zhang, Vincent M Crowley, Thomas G Wucherpfennig, Melissa M Dix, Benjamin F Cravatt. Nat Chem Biol 2019
106
20


Lysosome-targeting chimaeras for degradation of extracellular proteins.
Steven M Banik, Kayvon Pedram, Simon Wisnovsky, Green Ahn, Nicholas M Riley, Carolyn R Bertozzi. Nature 2020
99
20

Quantitative reactivity profiling predicts functional cysteines in proteomes.
Eranthie Weerapana, Chu Wang, Gabriel M Simon, Florian Richter, Sagar Khare, Myles B D Dillon, Daniel A Bachovchin, Kerri Mowen, David Baker, Benjamin F Cravatt. Nature 2010
798
20

Development of Dual and Selective Degraders of Cyclin-Dependent Kinases 4 and 6.
Baishan Jiang, Eric S Wang, Katherine A Donovan, Yanke Liang, Eric S Fischer, Tinghu Zhang, Nathanael S Gray. Angew Chem Int Ed Engl 2019
90
20


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.