Rebecca E Brown, Catherine H Freudenreich. Curr Opin Genet Dev 2021
Times Cited: 7
Times Cited: 7
Times Cited
Times Co-cited
Similarity
On the wrong DNA track: Molecular mechanisms of repeat-mediated genome instability.
Alexandra N Khristich, Sergei M Mirkin. J Biol Chem 2020
Alexandra N Khristich, Sergei M Mirkin. J Biol Chem 2020
57
On the wrong DNA track: Molecular mechanisms of repeat-mediated genome instability.
Alexandra N Khristich, Sergei M Mirkin. J Biol Chem 2020
Alexandra N Khristich, Sergei M Mirkin. J Biol Chem 2020
57
Human MutLγ, the MLH1-MLH3 heterodimer, is an endonuclease that promotes DNA expansion.
Lyudmila Y Kadyrova, Vaibhavi Gujar, Vickers Burdett, Paul L Modrich, Farid A Kadyrov. Proc Natl Acad Sci U S A 2020
Lyudmila Y Kadyrova, Vaibhavi Gujar, Vickers Burdett, Paul L Modrich, Farid A Kadyrov. Proc Natl Acad Sci U S A 2020
57
Disease-associated repeat instability and mismatch repair.
Monika H M Schmidt, Christopher E Pearson. DNA Repair (Amst) 2016
Monika H M Schmidt, Christopher E Pearson. DNA Repair (Amst) 2016
57
FAN1 protects against repeat expansions in a Fragile X mouse model.
Xiao-Nan Zhao, Karen Usdin. DNA Repair (Amst) 2018
Xiao-Nan Zhao, Karen Usdin. DNA Repair (Amst) 2018
42
Repeat instability: mechanisms of dynamic mutations.
Christopher E Pearson, Kerrie Nichol Edamura, John D Cleary. Nat Rev Genet 2005
Christopher E Pearson, Kerrie Nichol Edamura, John D Cleary. Nat Rev Genet 2005
42
Isolated short CTG/CAG DNA slip-outs are repaired efficiently by hMutSbeta, but clustered slip-outs are poorly repaired.
Gagan B Panigrahi, Meghan M Slean, Jodie P Simard, Opher Gileadi, Christopher E Pearson. Proc Natl Acad Sci U S A 2010
Gagan B Panigrahi, Meghan M Slean, Jodie P Simard, Opher Gileadi, Christopher E Pearson. Proc Natl Acad Sci U S A 2010
42
Tissue- and age-specific DNA replication patterns at the CTG/CAG-expanded human myotonic dystrophy type 1 locus.
John D Cleary, Stéphanie Tomé, Arturo López Castel, Gagan B Panigrahi, Laurent Foiry, Katharine A Hagerman, Hana Sroka, David Chitayat, Geneviève Gourdon, Christopher E Pearson. Nat Struct Mol Biol 2010
John D Cleary, Stéphanie Tomé, Arturo López Castel, Gagan B Panigrahi, Laurent Foiry, Katharine A Hagerman, Hana Sroka, David Chitayat, Geneviève Gourdon, Christopher E Pearson. Nat Struct Mol Biol 2010
42
A slipped-CAG DNA-binding small molecule induces trinucleotide-repeat contractions in vivo.
Masayuki Nakamori, Gagan B Panigrahi, Stella Lanni, Terence Gall-Duncan, Hideki Hayakawa, Hana Tanaka, Jennifer Luo, Takahiro Otabe, Jinxing Li, Akihiro Sakata,[...]. Nat Genet 2020
Masayuki Nakamori, Gagan B Panigrahi, Stella Lanni, Terence Gall-Duncan, Hideki Hayakawa, Hana Tanaka, Jennifer Luo, Takahiro Otabe, Jinxing Li, Akihiro Sakata,[...]. Nat Genet 2020
42
42
Extrahelical (CAG)/(CTG) triplet repeat elements support proliferating cell nuclear antigen loading and MutLα endonuclease activation.
Anna Pluciennik, Vickers Burdett, Celia Baitinger, Ravi R Iyer, Kevin Shi, Paul Modrich. Proc Natl Acad Sci U S A 2013
Anna Pluciennik, Vickers Burdett, Celia Baitinger, Ravi R Iyer, Kevin Shi, Paul Modrich. Proc Natl Acad Sci U S A 2013
42
42
Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome.
A J Verkerk, M Pieretti, J S Sutcliffe, Y H Fu, D P Kuhl, A Pizzuti, O Reiner, S Richards, M F Victoria, F P Zhang. Cell 1991
A J Verkerk, M Pieretti, J S Sutcliffe, Y H Fu, D P Kuhl, A Pizzuti, O Reiner, S Richards, M F Victoria, F P Zhang. Cell 1991
42
Repeat instability during DNA repair: Insights from model systems.
Karen Usdin, Nealia C M House, Catherine H Freudenreich. Crit Rev Biochem Mol Biol 2015
Karen Usdin, Nealia C M House, Catherine H Freudenreich. Crit Rev Biochem Mol Biol 2015
42
Replication stress at microsatellites causes DNA double-strand breaks and break-induced replication.
Rujuta Yashodhan Gadgil, Eric J Romer, Caitlin C Goodman, S Dean Rider, French J Damewood, Joanna R Barthelemy, Kazuo Shin-Ya, Helmut Hanenberg, Michael Leffak. J Biol Chem 2020
Rujuta Yashodhan Gadgil, Eric J Romer, Caitlin C Goodman, S Dean Rider, French J Damewood, Joanna R Barthelemy, Kazuo Shin-Ya, Helmut Hanenberg, Michael Leffak. J Biol Chem 2020
42
The role of break-induced replication in large-scale expansions of (CAG)n/(CTG)n repeats.
Jane C Kim, Samantha T Harris, Teresa Dinter, Kartik A Shah, Sergei M Mirkin. Nat Struct Mol Biol 2017
Jane C Kim, Samantha T Harris, Teresa Dinter, Kartik A Shah, Sergei M Mirkin. Nat Struct Mol Biol 2017
42
DNA Repair in Huntington's Disease and Spinocerebellar Ataxias: Somatic Instability and Alternative Hypotheses.
Tamara Maiuri, Claudia L K Hung, Celeste Suart, Nola Begeja, Carlos Barba-Bazan, Yi Peng, Natasha Savic, Timothy Wong, Ray Truant. J Huntingtons Dis 2021
Tamara Maiuri, Claudia L K Hung, Celeste Suart, Nola Begeja, Carlos Barba-Bazan, Yi Peng, Natasha Savic, Timothy Wong, Ray Truant. J Huntingtons Dis 2021
28
Alternative DNA Structures In Vivo: Molecular Evidence and Remaining Questions.
Lucie Poggi, Guy-Franck Richard. Microbiol Mol Biol Rev 2020
Lucie Poggi, Guy-Franck Richard. Microbiol Mol Biol Rev 2020
28
Double-strand break repair plays a role in repeat instability in a fragile X mouse model.
Inbal Gazy, Bruce Hayward, Svetlana Potapova, Xiaonan Zhao, Karen Usdin. DNA Repair (Amst) 2019
Inbal Gazy, Bruce Hayward, Svetlana Potapova, Xiaonan Zhao, Karen Usdin. DNA Repair (Amst) 2019
28
Double-strand break repair pathways protect against CAG/CTG repeat expansions, contractions and repeat-mediated chromosomal fragility in Saccharomyces cerevisiae.
Rangapriya Sundararajan, Lionel Gellon, Rachel M Zunder, Catherine H Freudenreich. Genetics 2010
Rangapriya Sundararajan, Lionel Gellon, Rachel M Zunder, Catherine H Freudenreich. Genetics 2010
28
Huntington's Disease Pathogenesis: Two Sequential Components.
Eun Pyo Hong, Marcy E MacDonald, Vanessa C Wheeler, Lesley Jones, Peter Holmans, Michael Orth, Darren G Monckton, Jeffrey D Long, Seung Kwak, James F Gusella,[...]. J Huntingtons Dis 2021
Eun Pyo Hong, Marcy E MacDonald, Vanessa C Wheeler, Lesley Jones, Peter Holmans, Michael Orth, Darren G Monckton, Jeffrey D Long, Seung Kwak, James F Gusella,[...]. J Huntingtons Dis 2021
28
Recombination-induced CAG trinucleotide repeat expansions in yeast involve the MRE11-RAD50-XRS2 complex.
G F Richard, G M Goellner, C T McMurray, J E Haber. EMBO J 2000
G F Richard, G M Goellner, C T McMurray, J E Haber. EMBO J 2000
28
MutLγ promotes repeat expansion in a Fragile X mouse model while EXO1 is protective.
Xiaonan Zhao, Yongwei Zhang, Kenneth Wilkins, Winfried Edelmann, Karen Usdin. PLoS Genet 2018
Xiaonan Zhao, Yongwei Zhang, Kenneth Wilkins, Winfried Edelmann, Karen Usdin. PLoS Genet 2018
28
Processing of double-R-loops in (CAG)·(CTG) and C9orf72 (GGGGCC)·(GGCCCC) repeats causes instability.
Kaalak Reddy, Monika H M Schmidt, Jaimie M Geist, Neha P Thakkar, Gagan B Panigrahi, Yuh-Hwa Wang, Christopher E Pearson. Nucleic Acids Res 2014
Kaalak Reddy, Monika H M Schmidt, Jaimie M Geist, Neha P Thakkar, Gagan B Panigrahi, Yuh-Hwa Wang, Christopher E Pearson. Nucleic Acids Res 2014
28
Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2.
Craig MacKay, Anne-Cécile Déclais, Cecilia Lundin, Ana Agostinho, Andrew J Deans, Thomas J MacArtney, Kay Hofmann, Anton Gartner, Stephen C West, Thomas Helleday,[...]. Cell 2010
Craig MacKay, Anne-Cécile Déclais, Cecilia Lundin, Ana Agostinho, Andrew J Deans, Thomas J MacArtney, Kay Hofmann, Anton Gartner, Stephen C West, Thomas Helleday,[...]. Cell 2010
28
DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1.
Renjing Wang, Nicole S Persky, Barney Yoo, Ouathek Ouerfelli, Agata Smogorzewska, Stephen J Elledge, Nikola P Pavletich. Science 2014
Renjing Wang, Nicole S Persky, Barney Yoo, Ouathek Ouerfelli, Agata Smogorzewska, Stephen J Elledge, Nikola P Pavletich. Science 2014
28
Genetic and Functional Analyses Point to FAN1 as the Source of Multiple Huntington Disease Modifier Effects.
Kyung-Hee Kim, Eun Pyo Hong, Jun Wan Shin, Michael J Chao, Jacob Loupe, Tammy Gillis, Jayalakshmi S Mysore, Peter Holmans, Lesley Jones, Michael Orth,[...]. Am J Hum Genet 2020
Kyung-Hee Kim, Eun Pyo Hong, Jun Wan Shin, Michael J Chao, Jacob Loupe, Tammy Gillis, Jayalakshmi S Mysore, Peter Holmans, Lesley Jones, Michael Orth,[...]. Am J Hum Genet 2020
28
FAN1 interaction with ubiquitylated PCNA alleviates replication stress and preserves genomic integrity independently of BRCA2.
Antonio Porro, Matteo Berti, Julia Pizzolato, Serena Bologna, Svenja Kaden, Anja Saxer, Yue Ma, Kazuo Nagasawa, Alessandro A Sartori, Josef Jiricny. Nat Commun 2017
Antonio Porro, Matteo Berti, Julia Pizzolato, Serena Bologna, Svenja Kaden, Anja Saxer, Yue Ma, Kazuo Nagasawa, Alessandro A Sartori, Josef Jiricny. Nat Commun 2017
28
The central role of DNA damage and repair in CAG repeat diseases.
Thomas H Massey, Lesley Jones. Dis Model Mech 2018
Thomas H Massey, Lesley Jones. Dis Model Mech 2018
28
Structural insights into 5' flap DNA unwinding and incision by the human FAN1 dimer.
Qi Zhao, Xiaoyu Xue, Simonne Longerich, Patrick Sung, Yong Xiong. Nat Commun 2014
Qi Zhao, Xiaoyu Xue, Simonne Longerich, Patrick Sung, Yong Xiong. Nat Commun 2014
28
Genome-wide detection of tandem DNA repeats that are expanded in autism.
Brett Trost, Worrawat Engchuan, Charlotte M Nguyen, Bhooma Thiruvahindrapuram, Egor Dolzhenko, Ian Backstrom, Mila Mirceta, Bahareh A Mojarad, Yue Yin, Alona Dov,[...]. Nature 2020
Brett Trost, Worrawat Engchuan, Charlotte M Nguyen, Bhooma Thiruvahindrapuram, Egor Dolzhenko, Ian Backstrom, Mila Mirceta, Bahareh A Mojarad, Yue Yin, Alona Dov,[...]. Nature 2020
28
KIAA1018/FAN1 nuclease protects cells against genomic instability induced by interstrand cross-linking agents.
Kazunori Yoshikiyo, Katja Kratz, Kouji Hirota, Kana Nishihara, Minoru Takata, Hitoshi Kurumizaka, Satoshi Horimoto, Shunichi Takeda, Josef Jiricny. Proc Natl Acad Sci U S A 2010
Kazunori Yoshikiyo, Katja Kratz, Kouji Hirota, Kana Nishihara, Minoru Takata, Hitoshi Kurumizaka, Satoshi Horimoto, Shunichi Takeda, Josef Jiricny. Proc Natl Acad Sci U S A 2010
28
Expansion and length-dependent fragility of CTG repeats in yeast.
C H Freudenreich, S M Kantrow, V A Zakian. Science 1998
C H Freudenreich, S M Kantrow, V A Zakian. Science 1998
28
Modifiers of CAG/CTG Repeat Instability: Insights from Mammalian Models.
Vanessa C Wheeler, Vincent Dion. J Huntingtons Dis 2021
Vanessa C Wheeler, Vincent Dion. J Huntingtons Dis 2021
28
Detection of slipped-DNAs at the trinucleotide repeats of the myotonic dystrophy type I disease locus in patient tissues.
Michelle M Axford, Yuh-Hwa Wang, Masayuki Nakamori, Maria Zannis-Hadjopoulos, Charles A Thornton, Christopher E Pearson. PLoS Genet 2013
Michelle M Axford, Yuh-Hwa Wang, Masayuki Nakamori, Maria Zannis-Hadjopoulos, Charles A Thornton, Christopher E Pearson. PLoS Genet 2013
28
DNA Mismatch Repair and its Role in Huntington's Disease.
Ravi R Iyer, Anna Pluciennik. J Huntingtons Dis 2021
Ravi R Iyer, Anna Pluciennik. J Huntingtons Dis 2021
28
Evidence of cis-acting factors in replication-mediated trinucleotide repeat instability in primate cells.
John D Cleary, Kerrie Nichol, Yuh-Hwa Wang, Christopher E Pearson. Nat Genet 2002
John D Cleary, Kerrie Nichol, Yuh-Hwa Wang, Christopher E Pearson. Nat Genet 2002
28
Replication inhibitors modulate instability of an expanded trinucleotide repeat at the myotonic dystrophy type 1 disease locus in human cells.
Zhi Yang, Rachel Lau, Julien L Marcadier, David Chitayat, Christopher E Pearson. Am J Hum Genet 2003
Zhi Yang, Rachel Lau, Julien L Marcadier, David Chitayat, Christopher E Pearson. Am J Hum Genet 2003
28
Importance of homo-dimerization of Fanconi-associated nuclease 1 in DNA flap cleavage.
Timsi Rao, Simonne Longerich, Weixing Zhao, Hideki Aihara, Patrick Sung, Yong Xiong. DNA Repair (Amst) 2018
Timsi Rao, Simonne Longerich, Weixing Zhao, Hideki Aihara, Patrick Sung, Yong Xiong. DNA Repair (Amst) 2018
50
Human FAN1 promotes strand incision in 5'-flapped DNA complexed with RPA.
Daisuke Takahashi, Koichi Sato, Emiko Hirayama, Minoru Takata, Hitoshi Kurumizaka. J Biochem 2015
Daisuke Takahashi, Koichi Sato, Emiko Hirayama, Minoru Takata, Hitoshi Kurumizaka. J Biochem 2015
28
A genetic association study of glutamine-encoding DNA sequence structures, somatic CAG expansion, and DNA repair gene variants, with Huntington disease clinical outcomes.
Marc Ciosi, Alastair Maxwell, Sarah A Cumming, Davina J Hensman Moss, Asma M Alshammari, Michael D Flower, Alexandra Durr, Blair R Leavitt, Raymund A C Roos, Peter Holmans,[...]. EBioMedicine 2019
Marc Ciosi, Alastair Maxwell, Sarah A Cumming, Davina J Hensman Moss, Asma M Alshammari, Michael D Flower, Alexandra Durr, Blair R Leavitt, Raymund A C Roos, Peter Holmans,[...]. EBioMedicine 2019
28
Mutations in yeast replication proteins that increase CAG/CTG expansions also increase repeat fragility.
Julie L Callahan, Kenneth J Andrews, Virginia A Zakian, Catherine H Freudenreich. Mol Cell Biol 2003
Julie L Callahan, Kenneth J Andrews, Virginia A Zakian, Catherine H Freudenreich. Mol Cell Biol 2003
28
R loops stimulate genetic instability of CTG.CAG repeats.
Yunfu Lin, Sharon Y R Dent, John H Wilson, Robert D Wells, Marek Napierala. Proc Natl Acad Sci U S A 2010
Yunfu Lin, Sharon Y R Dent, John H Wilson, Robert D Wells, Marek Napierala. Proc Natl Acad Sci U S A 2010
28
Promotion of somatic CAG repeat expansion by Fan1 knock-out in Huntington's disease knock-in mice is blocked by Mlh1 knock-out.
Jacob M Loupe, Ricardo Mouro Pinto, Kyung-Hee Kim, Tammy Gillis, Jayalakshmi S Mysore, Marissa A Andrew, Marina Kovalenko, Ryan Murtha, IhnSik Seong, James F Gusella,[...]. Hum Mol Genet 2020
Jacob M Loupe, Ricardo Mouro Pinto, Kyung-Hee Kim, Tammy Gillis, Jayalakshmi S Mysore, Marissa A Andrew, Marina Kovalenko, Ryan Murtha, IhnSik Seong, James F Gusella,[...]. Hum Mol Genet 2020
28
Complementary roles for exonuclease 1 and Flap endonuclease 1 in maintenance of triplet repeats.
Aarthy C Vallur, Nancy Maizels. J Biol Chem 2010
Aarthy C Vallur, Nancy Maizels. J Biol Chem 2010
28
MSH2 ATPase domain mutation affects CTG*CAG repeat instability in transgenic mice.
Stéphanie Tomé, Ian Holt, Winfried Edelmann, Glenn E Morris, Arnold Munnich, Christopher E Pearson, Geneviève Gourdon. PLoS Genet 2009
Stéphanie Tomé, Ian Holt, Winfried Edelmann, Glenn E Morris, Arnold Munnich, Christopher E Pearson, Geneviève Gourdon. PLoS Genet 2009
28
28
Interrupting sequence variants and age of onset in Huntington's disease: clinical implications and emerging therapies.
Galen E B Wright, Hailey Findlay Black, Jennifer A Collins, Terence Gall-Duncan, Nicholas S Caron, Christopher E Pearson, Michael R Hayden. Lancet Neurol 2020
Galen E B Wright, Hailey Findlay Black, Jennifer A Collins, Terence Gall-Duncan, Nicholas S Caron, Christopher E Pearson, Michael R Hayden. Lancet Neurol 2020
28
FAN1 modifies Huntington's disease progression by stabilizing the expanded HTT CAG repeat.
Robert Goold, Michael Flower, Davina Hensman Moss, Chris Medway, Alison Wood-Kaczmar, Ralph Andre, Pamela Farshim, Gill P Bates, Peter Holmans, Lesley Jones,[...]. Hum Mol Genet 2019
Robert Goold, Michael Flower, Davina Hensman Moss, Chris Medway, Alison Wood-Kaczmar, Ralph Andre, Pamela Farshim, Gill P Bates, Peter Holmans, Lesley Jones,[...]. Hum Mol Genet 2019
28
Deficiency of FANCD2-associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agents.
Katja Kratz, Barbara Schöpf, Svenja Kaden, Ataman Sendoel, Ralf Eberhard, Claudio Lademann, Elda Cannavó, Alessandro A Sartori, Michael O Hengartner, Josef Jiricny. Cell 2010
Katja Kratz, Barbara Schöpf, Svenja Kaden, Ataman Sendoel, Ralf Eberhard, Claudio Lademann, Elda Cannavó, Alessandro A Sartori, Michael O Hengartner, Josef Jiricny. Cell 2010
28
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.