Masayuki Nakamori, Hideki Mochizuki. Mov Disord 2021
Times Cited: 5
Times Cited: 5
Times Cited
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A slipped-CAG DNA-binding small molecule induces trinucleotide-repeat contractions in vivo.
Masayuki Nakamori, Gagan B Panigrahi, Stella Lanni, Terence Gall-Duncan, Hideki Hayakawa, Hana Tanaka, Jennifer Luo, Takahiro Otabe, Jinxing Li, Akihiro Sakata,[...]. Nat Genet 2020
Masayuki Nakamori, Gagan B Panigrahi, Stella Lanni, Terence Gall-Duncan, Hideki Hayakawa, Hana Tanaka, Jennifer Luo, Takahiro Otabe, Jinxing Li, Akihiro Sakata,[...]. Nat Genet 2020
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CAG Repeat Not Polyglutamine Length Determines Timing of Huntington's Disease Onset.
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Suppression of Somatic Expansion Delays the Onset of Pathophysiology in a Mouse Model of Huntington's Disease.
Helen Budworth, Faye R Harris, Paul Williams, Do Yup Lee, Amy Holt, Jens Pahnke, Bartosz Szczesny, Karina Acevedo-Torres, Sylvette Ayala-Peña, Cynthia T McMurray. PLoS Genet 2015
Helen Budworth, Faye R Harris, Paul Williams, Do Yup Lee, Amy Holt, Jens Pahnke, Bartosz Szczesny, Karina Acevedo-Torres, Sylvette Ayala-Peña, Cynthia T McMurray. PLoS Genet 2015
40
A modifier of Huntington's disease onset at the MLH1 locus.
Jong-Min Lee, Michael J Chao, Denise Harold, Kawther Abu Elneel, Tammy Gillis, Peter Holmans, Lesley Jones, Michael Orth, Richard H Myers, Seung Kwak,[...]. Hum Mol Genet 2017
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Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study.
Davina J Hensman Moss, Antonio F Pardiñas, Douglas Langbehn, Kitty Lo, Blair R Leavitt, Raymund Roos, Alexandra Durr, Simon Mead, Peter Holmans, Lesley Jones,[...]. Lancet Neurol 2017
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Identification of Genetic Factors that Modify Clinical Onset of Huntington's Disease.
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Gene ontology analysis for RNA-seq: accounting for selection bias.
Matthew D Young, Matthew J Wakefield, Gordon K Smyth, Alicia Oshlack. Genome Biol 2010
Matthew D Young, Matthew J Wakefield, Gordon K Smyth, Alicia Oshlack. Genome Biol 2010
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Aberrant Myokine Signaling in Congenital Myotonic Dystrophy.
Masayuki Nakamori, Kohei Hamanaka, James D Thomas, Eric T Wang, Yukiko K Hayashi, Masanori P Takahashi, Maurice S Swanson, Ichizo Nishino, Hideki Mochizuki. Cell Rep 2017
Masayuki Nakamori, Kohei Hamanaka, James D Thomas, Eric T Wang, Yukiko K Hayashi, Masanori P Takahashi, Maurice S Swanson, Ichizo Nishino, Hideki Mochizuki. Cell Rep 2017
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The cell cycle as a therapeutic target for Alzheimer's disease.
Rachael L Neve, Donna L McPhie. Pharmacol Ther 2006
Rachael L Neve, Donna L McPhie. Pharmacol Ther 2006
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Epigenetic Mechanisms of Gene Regulation in Amyotrophic Lateral Sclerosis.
Alba Jimenez-Pacheco, Jaime M Franco, Soledad Lopez, Juan Miguel Gomez-Zumaquero, Maria Magdalena Leal-Lasarte, Diana E Caballero-Hernandez, Marta Cejudo-Guillén, David Pozo. Adv Exp Med Biol 2017
Alba Jimenez-Pacheco, Jaime M Franco, Soledad Lopez, Juan Miguel Gomez-Zumaquero, Maria Magdalena Leal-Lasarte, Diana E Caballero-Hernandez, Marta Cejudo-Guillén, David Pozo. Adv Exp Med Biol 2017
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Reactive oxygen species participate in the p38-mediated apoptosis induced by potassium deprivation and staurosporine in cerebellar granule neurons.
Yazmín Ramiro-Cortés, Alicia Guemez-Gamboa, Julio Morán. Int J Biochem Cell Biol 2011
Yazmín Ramiro-Cortés, Alicia Guemez-Gamboa, Julio Morán. Int J Biochem Cell Biol 2011
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Amyloid β1-42 (Aβ1-42) Induces the CDK2-Mediated Phosphorylation of Tau through the Activation of the mTORC1 Signaling Pathway While Promoting Neuronal Cell Death.
Ki Hoon Lee, Sei-Jung Lee, Hyun Jik Lee, Gee Euhn Choi, Young Hyun Jung, Dah Ihm Kim, Amr Ahmed Gabr, Jung Min Ryu, Ho Jae Han. Front Mol Neurosci 2017
Ki Hoon Lee, Sei-Jung Lee, Hyun Jik Lee, Gee Euhn Choi, Young Hyun Jung, Dah Ihm Kim, Amr Ahmed Gabr, Jung Min Ryu, Ho Jae Han. Front Mol Neurosci 2017
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3-Nitropropionic acid activates calpain/cdk5 pathway in rat striatum.
Natalia Crespo-Biel, Antoni Camins, Carme Pelegrí, Jordi Vilaplana, Mercè Pallàs, Anna M Canudas. Neurosci Lett 2007
Natalia Crespo-Biel, Antoni Camins, Carme Pelegrí, Jordi Vilaplana, Mercè Pallàs, Anna M Canudas. Neurosci Lett 2007
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Context-Dependent Functions of E2F1: Cell Cycle, Cell Death, and DNA Damage Repair in Cortical Neurons.
Yang Zhang, Xuan Song, Karl Herrup. Mol Neurobiol 2020
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Selective Brain-Targeted Antagonism of p38 MAPKα Reduces Hippocampal IL-1β Levels and Improves Morris Water Maze Performance in Aged Rats.
John J Alam. J Alzheimers Dis 2015
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The cell cycle Cdc25A tyrosine phosphatase is activated in degenerating postmitotic neurons in Alzheimer's disease.
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beta-Amyloid fibrils activate parallel mitogen-activated protein kinase pathways in microglia and THP1 monocytes.
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Specific inhibition of p25/Cdk5 activity by the Cdk5 inhibitory peptide reduces neurodegeneration in vivo.
Jeyapriya Raja Sundaram, Charlene Priscilla Poore, Noor Hazim Bin Sulaimee, Tej Pareek, A B M A Asad, Ramamoorthy Rajkumar, Wei Fun Cheong, Markus R Wenk, Gavin Stewart Dawe, Kai-Hsiang Chuang,[...]. J Neurosci 2013
Jeyapriya Raja Sundaram, Charlene Priscilla Poore, Noor Hazim Bin Sulaimee, Tej Pareek, A B M A Asad, Ramamoorthy Rajkumar, Wei Fun Cheong, Markus R Wenk, Gavin Stewart Dawe, Kai-Hsiang Chuang,[...]. J Neurosci 2013
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MAPK-activated protein kinase 2 deficiency in microglia inhibits pro-inflammatory mediator release and resultant neurotoxicity. Relevance to neuroinflammation in a transgenic mouse model of Alzheimer disease.
Ainsley A Culbert, Stephen D Skaper, David R Howlett, Nicholas A Evans, Laura Facci, Peter E Soden, Zoe M Seymour, Florence Guillot, Matthias Gaestel, Jill C Richardson. J Biol Chem 2006
Ainsley A Culbert, Stephen D Skaper, David R Howlett, Nicholas A Evans, Laura Facci, Peter E Soden, Zoe M Seymour, Florence Guillot, Matthias Gaestel, Jill C Richardson. J Biol Chem 2006
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Activation of MKK6, an upstream activator of p38, in Alzheimer's disease.
X Zhu, C A Rottkamp, A Hartzler, Z Sun, A Takeda, H Boux, S Shimohama, G Perry, M A Smith. J Neurochem 2001
X Zhu, C A Rottkamp, A Hartzler, Z Sun, A Takeda, H Boux, S Shimohama, G Perry, M A Smith. J Neurochem 2001
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Downregulation of NF-kappaB signaling by mutant huntingtin proteins induces oxidative stress and cell death.
Sami Reijonen, Jyrki P Kukkonen, Alise Hyrskyluoto, Jenny Kivinen, Minna Kairisalo, Nobuyuki Takei, Dan Lindholm, Laura Korhonen. Cell Mol Life Sci 2010
Sami Reijonen, Jyrki P Kukkonen, Alise Hyrskyluoto, Jenny Kivinen, Minna Kairisalo, Nobuyuki Takei, Dan Lindholm, Laura Korhonen. Cell Mol Life Sci 2010
20
Glycogen synthase protects neurons from cytotoxicity of mutant huntingtin by enhancing the autophagy flux.
Anupama Rai, Pankaj Kumar Singh, Virender Singh, Vipendra Kumar, Rohit Mishra, Ashwani Kumar Thakur, Anita Mahadevan, Susarla Krishna Shankar, Nihar Ranjan Jana, Subramaniam Ganesh. Cell Death Dis 2018
Anupama Rai, Pankaj Kumar Singh, Virender Singh, Vipendra Kumar, Rohit Mishra, Ashwani Kumar Thakur, Anita Mahadevan, Susarla Krishna Shankar, Nihar Ranjan Jana, Subramaniam Ganesh. Cell Death Dis 2018
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Traffic signaling: new functions of huntingtin and axonal transport in neurological disease.
Hélène Vitet, Vicky Brandt, Frédéric Saudou. Curr Opin Neurobiol 2020
Hélène Vitet, Vicky Brandt, Frédéric Saudou. Curr Opin Neurobiol 2020
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The Effects of Pharmacological Inhibition of Histone Deacetylase 3 (HDAC3) in Huntington's Disease Mice.
Haiqun Jia, Ying Wang, Charles D Morris, Vincent Jacques, Joel M Gottesfeld, James R Rusche, Elizabeth A Thomas. PLoS One 2016
Haiqun Jia, Ying Wang, Charles D Morris, Vincent Jacques, Joel M Gottesfeld, James R Rusche, Elizabeth A Thomas. PLoS One 2016
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MicroRNA-124 regulates the expression of p62/p38 and promotes autophagy in the inflammatory pathogenesis of Parkinson's disease.
Longping Yao, Zhiyuan Zhu, Jiayu Wu, Yizhou Zhang, Hongbo Zhang, Xiang Sun, Chen Qian, Baoyan Wang, Linghai Xie, Shizhong Zhang,[...]. FASEB J 2019
Longping Yao, Zhiyuan Zhu, Jiayu Wu, Yizhou Zhang, Hongbo Zhang, Xiang Sun, Chen Qian, Baoyan Wang, Linghai Xie, Shizhong Zhang,[...]. FASEB J 2019
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Is There Justification to Treat Neurodegenerative Disorders by Repurposing Drugs? The Case of Alzheimer's Disease, Lithium, and Autophagy.
Odeya Damri, Nofar Shemesh, Galila Agam. Int J Mol Sci 2020
Odeya Damri, Nofar Shemesh, Galila Agam. Int J Mol Sci 2020
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Cyclin-dependent kinases: a family portrait.
Marcos Malumbres, Edward Harlow, Tim Hunt, Tony Hunter, Jill M Lahti, Gerard Manning, David O Morgan, Li-Huei Tsai, Debra J Wolgemuth. Nat Cell Biol 2009
Marcos Malumbres, Edward Harlow, Tim Hunt, Tony Hunter, Jill M Lahti, Gerard Manning, David O Morgan, Li-Huei Tsai, Debra J Wolgemuth. Nat Cell Biol 2009
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Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases in intact cells.
Valérie Buée-Scherrer, Michel Goedert. FEBS Lett 2002
Valérie Buée-Scherrer, Michel Goedert. FEBS Lett 2002
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Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase.
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Evidence for specific cognitive deficits in preclinical Huntington's disease.
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Dynamic range of GSK3α not GSK3β is essential for bidirectional synaptic plasticity at hippocampal CA3-CA1 synapses.
Lion Shahab, Florian Plattner, Elaine E Irvine, Damian M Cummings, Frances A Edwards. Hippocampus 2014
Lion Shahab, Florian Plattner, Elaine E Irvine, Damian M Cummings, Frances A Edwards. Hippocampus 2014
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Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease.
Hyoung-Gon Lee, Gemma Casadesus, Xiongwei Zhu, Rudy J Castellani, Andrew McShea, George Perry, Robert B Petersen, Vladan Bajic, Mark A Smith. Neurochem Int 2009
Hyoung-Gon Lee, Gemma Casadesus, Xiongwei Zhu, Rudy J Castellani, Andrew McShea, George Perry, Robert B Petersen, Vladan Bajic, Mark A Smith. Neurochem Int 2009
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Role of p38/MAPKs in Alzheimer's disease: implications for amyloid beta toxicity targeted therapy.
Ghazaleh Kheiri, Mahsa Dolatshahi, Farzaneh Rahmani, Nima Rezaei. Rev Neurosci 2018
Ghazaleh Kheiri, Mahsa Dolatshahi, Farzaneh Rahmani, Nima Rezaei. Rev Neurosci 2018
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Autophagy in Alzheimer's disease.
Ameneh Zare-Shahabadi, Eliezer Masliah, Gail V W Johnson, Nima Rezaei. Rev Neurosci 2015
Ameneh Zare-Shahabadi, Eliezer Masliah, Gail V W Johnson, Nima Rezaei. Rev Neurosci 2015
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3D brain Organoids derived from pluripotent stem cells: promising experimental models for brain development and neurodegenerative disorders.
Chun-Ting Lee, Raphael M Bendriem, Wells W Wu, Rong-Fong Shen. J Biomed Sci 2017
Chun-Ting Lee, Raphael M Bendriem, Wells W Wu, Rong-Fong Shen. J Biomed Sci 2017
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Depressive symptom severity is related to poorer cognitive performance in prodromal Huntington disease.
Megan M Smith, James A Mills, Eric A Epping, Holly J Westervelt, Jane S Paulsen. Neuropsychology 2012
Megan M Smith, James A Mills, Eric A Epping, Holly J Westervelt, Jane S Paulsen. Neuropsychology 2012
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Physiological and pathological phosphorylation of tau by Cdk5.
Taeko Kimura, Koichi Ishiguro, Shin-Ichi Hisanaga. Front Mol Neurosci 2014
Taeko Kimura, Koichi Ishiguro, Shin-Ichi Hisanaga. Front Mol Neurosci 2014
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p38(MAPK): stress responses from molecular mechanisms to therapeutics.
Lydia R Coulthard, Danielle E White, Dominic L Jones, Michael F McDermott, Susan A Burchill. Trends Mol Med 2009
Lydia R Coulthard, Danielle E White, Dominic L Jones, Michael F McDermott, Susan A Burchill. Trends Mol Med 2009
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Autophagy in Huntington disease and huntingtin in autophagy.
Dale D O Martin, Safia Ladha, Dagmar E Ehrnhoefer, Michael R Hayden. Trends Neurosci 2015
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Faulty splicing and cytoskeleton abnormalities in Huntington's disease.
Marta Fernández-Nogales, María Santos-Galindo, Ivó H Hernández, Jorge R Cabrera, José J Lucas. Brain Pathol 2016
Marta Fernández-Nogales, María Santos-Galindo, Ivó H Hernández, Jorge R Cabrera, José J Lucas. Brain Pathol 2016
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Pyrazolo[3,4-b]quinoxalines. A new class of cyclin-dependent kinases inhibitors.
Miguel A Ortega, María E Montoya, Belén Zarranz, Andrés Jaso, Ignacio Aldana, Sophie Leclerc, Laurent Meijer, Antonio Monge. Bioorg Med Chem 2002
Miguel A Ortega, María E Montoya, Belén Zarranz, Andrés Jaso, Ignacio Aldana, Sophie Leclerc, Laurent Meijer, Antonio Monge. Bioorg Med Chem 2002
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Cyclin-dependent kinase-5 in neurodegeneration.
Shirley B Shelton, Gail V W Johnson. J Neurochem 2004
Shirley B Shelton, Gail V W Johnson. J Neurochem 2004
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Lipid nanoparticles for intranasal administration: application to nose-to-brain delivery.
Luigi Battaglia, Pier Paolo Panciani, Elisabetta Muntoni, Maria Teresa Capucchio, Elena Biasibetti, Pasquale De Bonis, Silvia Mioletti, Marco Fontanella, Shankar Swaminathan. Expert Opin Drug Deliv 2018
Luigi Battaglia, Pier Paolo Panciani, Elisabetta Muntoni, Maria Teresa Capucchio, Elena Biasibetti, Pasquale De Bonis, Silvia Mioletti, Marco Fontanella, Shankar Swaminathan. Expert Opin Drug Deliv 2018
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A phase II trial of tideglusib in Alzheimer's disease.
Simon Lovestone, Mercè Boada, Bruno Dubois, Michael Hüll, Juha O Rinne, Hans-Jürgen Huppertz, Miguel Calero, María V Andrés, Belén Gómez-Carrillo, Teresa León,[...]. J Alzheimers Dis 2015
Simon Lovestone, Mercè Boada, Bruno Dubois, Michael Hüll, Juha O Rinne, Hans-Jürgen Huppertz, Miguel Calero, María V Andrés, Belén Gómez-Carrillo, Teresa León,[...]. J Alzheimers Dis 2015
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Nanoparticle transport across the blood brain barrier.
Andreas M Grabrucker, Barbara Ruozi, Daniela Belletti, Francesca Pederzoli, Flavio Forni, Maria Angela Vandelli, Giovanni Tosi. Tissue Barriers 2016
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Oligodendrogliopathy in neurodegenerative diseases with abnormal protein aggregates: The forgotten partner.
Isidro Ferrer. Prog Neurobiol 2018
Isidro Ferrer. Prog Neurobiol 2018
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