A citation-based method for searching scientific literature

Adam G Schwaid, Kerrie B Spencer. J Med Chem 2021
Times Cited: 11







List of co-cited articles
42 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.
Rebecca C Coll, Avril A B Robertson, Jae Jin Chae, Sarah C Higgins, Raúl Muñoz-Planillo, Marco C Inserra, Irina Vetter, Lara S Dungan, Brian G Monks, Andrea Stutz,[...]. Nat Med 2015
45

The NLRP3 inflammasome: molecular activation and regulation to therapeutics.
Karen V Swanson, Meng Deng, Jenny P-Y Ting. Nat Rev Immunol 2019
849
36

Targeting the NLRP3 inflammasome in inflammatory diseases.
Matthew S J Mangan, Edward J Olhava, William R Roush, H Martin Seidel, Gary D Glick, Eicke Latz. Nat Rev Drug Discov 2018
419
27

Mechanism and Regulation of NLRP3 Inflammasome Activation.
Yuan He, Hideki Hara, Gabriel Núñez. Trends Biochem Sci 2016
27

NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.
Michael T Heneka, Markus P Kummer, Andrea Stutz, Andrea Delekate, Stephanie Schwartz, Ana Vieira-Saecker, Angelika Griep, Daisy Axt, Anita Remus, Te-Chen Tzeng,[...]. Nature 2013
27

Anti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasome.
Christine Juliana, Teresa Fernandes-Alnemri, Jianghong Wu, Pinaki Datta, Leobaldo Solorzano, Je-Wook Yu, Rong Meng, Andrew A Quong, Eicke Latz, Charles P Scott,[...]. J Biol Chem 2010
319
27

OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation.
Carlo Marchetti, Benjamin Swartzwelter, Fabia Gamboni, Charles P Neff, Katrin Richter, Tania Azam, Sonia Carta, Isak Tengesdal, Travis Nemkov, Angelo D'Alessandro,[...]. Proc Natl Acad Sci U S A 2018
156
27

Discovery of Second-Generation NLRP3 Inflammasome Inhibitors: Design, Synthesis, and Biological Characterization.
Yuqi Jiang, Liu He, Jakob Green, Hallie Blevins, Chunqing Guo, Sulay Harsiddhbhai Patel, Matthew S Halquist, MaryPeace McRae, Jürgen Venitz, Xiang-Yang Wang,[...]. J Med Chem 2019
11
27

Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity.
Hongbin He, Hua Jiang, Yun Chen, Jin Ye, Aoli Wang, Chao Wang, Qingsong Liu, Gaolin Liang, Xianming Deng, Wei Jiang,[...]. Nat Commun 2018
190
27

Pharmacological Inhibitors of the NLRP3 Inflammasome.
Ayesha Zahid, Bofeng Li, Arnaud John Kombe Kombe, Tengchuan Jin, Jinhui Tao. Front Immunol 2019
159
27

Neuronal NLRP1 inflammasome activation of Caspase-1 coordinately regulates inflammatory interleukin-1-beta production and axonal degeneration-associated Caspase-6 activation.
V Kaushal, R Dye, P Pakavathkumar, B Foveau, J Flores, B Hyman, B Ghetti, B H Koller, A C LeBlanc. Cell Death Differ 2015
147
18

Pyroptosis: host cell death and inflammation.
Tessa Bergsbaken, Susan L Fink, Brad T Cookson. Nat Rev Microbiol 2009
18

PET imaging of neuroinflammation in neurological disorders.
William C Kreisl, Min-Jeong Kim, Jennifer M Coughlin, Ioline D Henter, David R Owen, Robert B Innis. Lancet Neurol 2020
28
18

Neuroinflammation PET Imaging: Current Opinion and Future Directions.
Poorva Jain, Aisling M Chaney, Mackenzie L Carlson, Isaac M Jackson, Anoushka Rao, Michelle L James. J Nucl Med 2020
15
18

Emerging PET Radiotracers and Targets for Imaging of Neuroinflammation in Neurodegenerative Diseases: Outlook Beyond TSPO.
Vidya Narayanaswami, Kenneth Dahl, Vadim Bernard-Gauthier, Lee Josephson, Paul Cumming, Neil Vasdev. Mol Imaging 2018
65
18

Inflammasomes: mechanism of assembly, regulation and signalling.
Petr Broz, Vishva M Dixit. Nat Rev Immunol 2016
18

Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome.
Christian Bauer, Peter Duewell, Christine Mayer, Hans Anton Lehr, Katherine A Fitzgerald, Marc Dauer, Jurg Tschopp, Stefan Endres, Eicke Latz, Max Schnurr. Gut 2010
441
18


Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders.
Hua Jiang, Hongbin He, Yun Chen, Wei Huang, Jinbo Cheng, Jin Ye, Aoli Wang, Jinhui Tao, Chao Wang, Qingsong Liu,[...]. J Exp Med 2017
234
18

Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease.
Mattia Cocco, Carolina Pellegrini, Helios Martínez-Banaclocha, Marta Giorgis, Elisabetta Marini, Annalisa Costale, Gianluca Miglio, Matteo Fornai, Luca Antonioli, Gloria López-Castejón,[...]. J Med Chem 2017
79
18

Activation and regulation of the inflammasomes.
Eicke Latz, T Sam Xiao, Andrea Stutz. Nat Rev Immunol 2013
18

Synthesis and biological evaluation of parthenolide derivatives with reduced toxicity as potential inhibitors of the NLRP3 inflammasome.
Yitao Ou, Ping Sun, Nannan Wu, Hao Chen, Dan Wu, Wenhui Hu, Zhongjin Yang. Bioorg Med Chem Lett 2020
3
66

NOD-like receptors: role in innate immunity and inflammatory disease.
Grace Chen, Michael H Shaw, Yun-Gi Kim, Gabriel Nuñez. Annu Rev Pathol 2009
472
18

Parkin and PINK1 mitigate STING-induced inflammation.
Danielle A Sliter, Jennifer Martinez, Ling Hao, Xi Chen, Nuo Sun, Tara D Fischer, Jonathon L Burman, Yan Li, Zhe Zhang, Derek P Narendra,[...]. Nature 2018
420
18

Development of small molecule inhibitors targeting NLRP3 inflammasome pathway for inflammatory diseases.
Xiangna Zhang, Ana Xu, Jiahui Lv, Qiuqiong Zhang, Yingying Ran, Chao Wei, Jingde Wu. Eur J Med Chem 2020
29
18

Inflammasomes: mechanism of action, role in disease, and therapeutics.
Haitao Guo, Justin B Callaway, Jenny P-Y Ting. Nat Med 2015
18

Tranilast directly targets NLRP3 to treat inflammasome-driven diseases.
Yi Huang, Hua Jiang, Yun Chen, Xiaqiong Wang, Yanqing Yang, Jinhui Tao, Xianming Deng, Gaolin Liang, Huafeng Zhang, Wei Jiang,[...]. EMBO Mol Med 2018
146
18

MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition.
Rebecca C Coll, James R Hill, Christopher J Day, Alina Zamoshnikova, Dave Boucher, Nicholas L Massey, Jessica L Chitty, James A Fraser, Michael P Jennings, Avril A B Robertson,[...]. Nat Chem Biol 2019
213
18

Discovery of a Novel cGAMP Competitive Ligand of the Inactive Form of STING.
Tony Siu, Michael D Altman, Gretchen A Baltus, Matthew Childers, J Michael Ellis, Hakan Gunaydin, Harold Hatch, Thu Ho, James Jewell, Brian M Lacey,[...]. ACS Med Chem Lett 2018
28
18

Modulation of the Innate Immune Response by Targeting Toll-like Receptors: A Perspective on Their Agonists and Antagonists.
Stefano Federico, Luca Pozzetti, Alessandro Papa, Gabriele Carullo, Sandra Gemma, Stefania Butini, Giuseppe Campiani, Nicola Relitti. J Med Chem 2020
25
18

Development of Novel Tetrahydroquinoline Inhibitors of NLRP3 Inflammasome for Potential Treatment of DSS-Induced Mouse Colitis.
Zhen Dai, Xiao-Yi Chen, Lu-Yan An, Cui-Cui Li, Ni Zhao, Fan Yang, Song-Tao You, Chen-Zhi Hou, Kan Li, Cheng Jiang,[...]. J Med Chem 2021
7
28

Discovery of N-Cyano-sulfoximineurea Derivatives as Potent and Orally Bioavailable NLRP3 Inflammasome Inhibitors.
Sameer Agarwal, Santosh Sasane, Hardik A Shah, Jignesh P Pethani, Prashant Deshmukh, Vismit Vyas, Pravin Iyer, Harsh Bhavsar, Kasinath Viswanathan, Debdutta Bandyopadhyay,[...]. ACS Med Chem Lett 2020
6
33

Structural Insights of Benzenesulfonamide Analogues as NLRP3 Inflammasome Inhibitors: Design, Synthesis, and Biological Characterization.
Jacob Fulp, Liu He, Stefano Toldo, Yuqi Jiang, Ashley Boice, Chunqing Guo, Xia Li, Andrew Rolfe, Dong Sun, Antonio Abbate,[...]. J Med Chem 2018
32
18

3,4-methylenedioxy-β-nitrostyrene inhibits NLRP3 inflammasome activation by blocking assembly of the inflammasome.
Yuan He, Saranyaraajan Varadarajan, Raúl Muñoz-Planillo, Aaron Burberry, Yuumi Nakamura, Gabriel Núñez. J Biol Chem 2014
131
18



Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death.
Jianjin Shi, Wenqing Gao, Feng Shao. Trends Biochem Sci 2017
707
18

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores.
Xing Liu, Zhibin Zhang, Jianbin Ruan, Youdong Pan, Venkat Giri Magupalli, Hao Wu, Judy Lieberman. Nature 2016
979
18


Non-canonical inflammasome activation targets caspase-11.
Nobuhiko Kayagaki, Søren Warming, Mohamed Lamkanfi, Lieselotte Vande Walle, Salina Louie, Jennifer Dong, Kim Newton, Yan Qu, Jinfeng Liu, Sherry Heldens,[...]. Nature 2011
18

Dapansutrile, an oral selective NLRP3 inflammasome inhibitor, for treatment of gout flares: an open-label, dose-adaptive, proof-of-concept, phase 2a trial.
Viola Klück, Tim L Th A Jansen, Matthijs Janssen, Antoaneta Comarniceanu, Monique Efdé, Isak W Tengesdal, Kiki Schraa, Maartje C P Cleophas, Curtis L Scribner, Damaris B Skouras,[...]. Lancet Rheumatol 2020
40
18

NLRP3 inflammasome in cancer and metabolic diseases.
Bhesh Raj Sharma, Thirumala-Devi Kanneganti. Nat Immunol 2021
19
18

ROS function in redox signaling and oxidative stress.
Michael Schieber, Navdeep S Chandel. Curr Biol 2014
9

Air pollution: mechanisms of neuroinflammation and CNS disease.
Michelle L Block, Lilian Calderón-Garcidueñas. Trends Neurosci 2009
612
9

Neuroinflammation in mild cognitive impairment and Alzheimer's disease: A meta-analysis.
Steven Bradburn, Christopher Murgatroyd, Nicola Ray. Ageing Res Rev 2019
52
9

Exploratory Clinical Investigation of (4S)-4-(3-18F-Fluoropropyl)-L-Glutamate PET of Inflammatory and Infectious Lesions.
Sun Young Chae, Chang-Min Choi, Tae Sun Shim, Yangsoon Park, Chan-Sik Park, Hyo Sang Lee, Sang Ju Lee, Seung Jun Oh, Seog-Young Kim, Sora Baek,[...]. J Nucl Med 2016
16
9

[(11)C]Ascorbic and [(11)C]dehydroascorbic acid, an endogenous redox pair for sensing reactive oxygen species using positron emission tomography.
V N Carroll, C Truillet, B Shen, R R Flavell, X Shao, M J Evans, H F VanBrocklin, P J H Scott, F T Chin, D M Wilson. Chem Commun (Camb) 2016
26
9

Lifestyle modification for stroke prevention: facts and fiction.
Maciej Niewada, Patrik Michel. Curr Opin Neurol 2016
13
9

Cytokine dysregulation, inflammation and well-being.
Ilia J Elenkov, Domenic G Iezzoni, Adrian Daly, Alan G Harris, George P Chrousos. Neuroimmunomodulation 2005
307
9

Protein oxidation in aging, disease, and oxidative stress.
B S Berlett, E R Stadtman. J Biol Chem 1997
9


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.