A citation-based method for searching scientific literature

Tuo Li, Tuozhi Huang, Mingjian Du, Xiang Chen, Fenghe Du, Junyao Ren, Zhijian J Chen. Science 2021
Times Cited: 27







List of co-cited articles
280 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Structural basis for the inhibition of cGAS by nucleosomes.
Tomoya Kujirai, Christian Zierhut, Yoshimasa Takizawa, Ryan Kim, Lumi Negishi, Nobuki Uruma, Seiya Hirai, Hironori Funabiki, Hitoshi Kurumizaka. Science 2020
55
55

Structural mechanism of cGAS inhibition by the nucleosome.
Ganesh R Pathare, Alexiane Decout, Selene Glück, Simone Cavadini, Kristina Makasheva, Ruud Hovius, Georg Kempf, Joscha Weiss, Zuzanna Kozicka, Baptiste Guey,[...]. Nature 2020
57
55

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway.
Lijun Sun, Jiaxi Wu, Fenghe Du, Xiang Chen, Zhijian J Chen. Science 2013
55

cGAS surveillance of micronuclei links genome instability to innate immunity.
Karen J Mackenzie, Paula Carroll, Carol-Anne Martin, Olga Murina, Adeline Fluteau, Daniel J Simpson, Nelly Olova, Hannah Sutcliffe, Jacqueline K Rainger, Andrea Leitch,[...]. Nature 2017
569
51

Structural basis for sequestration and autoinhibition of cGAS by chromatin.
Sebastian Michalski, Carina C de Oliveira Mann, Che A Stafford, Gregor Witte, Joseph Bartho, Katja Lammens, Veit Hornung, Karl-Peter Hopfner. Nature 2020
55
51

Structural basis of nucleosome-dependent cGAS inhibition.
Joshua A Boyer, Cathy J Spangler, Joshua D Strauss, Andrew P Cesmat, Pengda Liu, Robert K McGinty, Qi Zhang. Science 2020
53
48

Tight nuclear tethering of cGAS is essential for preventing autoreactivity.
Hannah E Volkman, Stephanie Cambier, Elizabeth E Gray, Daniel B Stetson. Elife 2019
78
48

The molecular basis of tight nuclear tethering and inactivation of cGAS.
Baoyu Zhao, Pengbiao Xu, Chesley M Rowlett, Tao Jing, Omkar Shinde, Yuanjiu Lei, A Phillip West, Wenshe Ray Liu, Pingwei Li. Nature 2020
50
48


The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death.
Christian Zierhut, Norihiro Yamaguchi, Maria Paredes, Ji-Dung Luo, Thomas Carroll, Hironori Funabiki. Cell 2019
123
40

Chromatin-bound cGAS is an inhibitor of DNA repair and hence accelerates genome destabilization and cell death.
Hui Jiang, Xiaoyu Xue, Swarupa Panda, Ajinkya Kawale, Richard M Hooy, Fengshan Liang, Jungsan Sohn, Patrick Sung, Nelson O Gekara. EMBO J 2019
75
40

Mitotic progression following DNA damage enables pattern recognition within micronuclei.
Shane M Harding, Joseph L Benci, Jerome Irianto, Dennis E Discher, Andy J Minn, Roger A Greenberg. Nature 2017
539
37

Nuclear cGAS suppresses DNA repair and promotes tumorigenesis.
Haipeng Liu, Haiping Zhang, Xiangyang Wu, Dapeng Ma, Juehui Wu, Lin Wang, Yan Jiang, Yiyan Fei, Chenggang Zhu, Rong Tan,[...]. Nature 2018
199
37

BAF restricts cGAS on nuclear DNA to prevent innate immune activation.
Baptiste Guey, Marilena Wischnewski, Alexiane Decout, Kristina Makasheva, Murat Kaynak, Mahmut S Sakar, Beat Fierz, Andrea Ablasser. Science 2020
35
33

cGAS is essential for cellular senescence.
Hui Yang, Hanze Wang, Junyao Ren, Qi Chen, Zhijian J Chen. Proc Natl Acad Sci U S A 2017
360
33

The N-Terminal Domain of cGAS Determines Preferential Association with Centromeric DNA and Innate Immune Activation in the Nucleus.
Matteo Gentili, Xavier Lahaye, Francesca Nadalin, Guilherme P F Nader, Emilia Puig Lombardi, Solène Herve, Nilushi S De Silva, Derek C Rookhuizen, Elina Zueva, Christel Goudot,[...]. Cell Rep 2019
70
33

Mitochondrial DNA stress primes the antiviral innate immune response.
A Phillip West, William Khoury-Hanold, Matthew Staron, Michal C Tal, Cristiana M Pineda, Sabine M Lang, Megan Bestwick, Brett A Duguay, Nuno Raimundo, Donna A MacDuff,[...]. Nature 2015
709
33

cGAS in action: Expanding roles in immunity and inflammation.
Andrea Ablasser, Zhijian J Chen. Science 2019
221
29

Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA.
Jiaxi Wu, Lijun Sun, Xiang Chen, Fenghe Du, Heping Shi, Chuo Chen, Zhijian J Chen. Science 2013
29

DNA sensing by the cGAS-STING pathway in health and disease.
Mona Motwani, Scott Pesiridis, Katherine A Fitzgerald. Nat Rev Genet 2019
263
29

Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence.
Selene Glück, Baptiste Guey, Muhammet Fatih Gulen, Katharina Wolter, Tae-Won Kang, Niklas Arndt Schmacke, Anne Bridgeman, Jan Rehwinkel, Lars Zender, Andrea Ablasser. Nat Cell Biol 2017
375
29

cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders.
Liudmila Andreeva, Björn Hiller, Dirk Kostrewa, Charlotte Lässig, Carina C de Oliveira Mann, David Jan Drexler, Andreas Maiser, Moritz Gaidt, Heinrich Leonhardt, Veit Hornung,[...]. Nature 2017
170
29

Cytoplasmic chromatin triggers inflammation in senescence and cancer.
Zhixun Dou, Kanad Ghosh, Maria Grazia Vizioli, Jiajun Zhu, Payel Sen, Kirk J Wangensteen, Johayra Simithy, Yemin Lan, Yanping Lin, Zhuo Zhou,[...]. Nature 2017
410
29

Structural basis for nucleosome-mediated inhibition of cGAS activity.
Duanfang Cao, Xiaonan Han, Xiaoyi Fan, Rui-Ming Xu, Xinzheng Zhang. Cell Res 2020
21
38


cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing.
Carolina Uggenti, Alice Lepelley, Marine Depp, Andrew P Badrock, Mathieu P Rodero, Marie-Thérèse El-Daher, Gillian I Rice, Somdutta Dhir, Ann P Wheeler, Ashish Dhir,[...]. Nat Genet 2020
32
25


Cyclic GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING.
Xu Zhang, Heping Shi, Jiaxi Wu, Xuewu Zhang, Lijun Sun, Chuo Chen, Zhijian J Chen. Mol Cell 2013
482
25

Chromosomal instability drives metastasis through a cytosolic DNA response.
Samuel F Bakhoum, Bryan Ngo, Ashley M Laughney, Julie-Ann Cavallo, Charles J Murphy, Peter Ly, Pragya Shah, Roshan K Sriram, Thomas B K Watkins, Neil K Taunk,[...]. Nature 2018
446
25

cGAS is activated by DNA in a length-dependent manner.
Stefanie Luecke, Andreas Holleufer, Maria H Christensen, Kasper L Jønsson, Gerardo A Boni, Lambert K Sørensen, Mogens Johannsen, Martin R Jakobsen, Rune Hartmann, Søren R Paludan. EMBO Rep 2017
97
25

Structural mechanism of cytosolic DNA sensing by cGAS.
Filiz Civril, Tobias Deimling, Carina C de Oliveira Mann, Andrea Ablasser, Manuela Moldt, Gregor Witte, Veit Hornung, Karl-Peter Hopfner. Nature 2013
356
25

Molecular mechanisms and cellular functions of cGAS-STING signalling.
Karl-Peter Hopfner, Veit Hornung. Nat Rev Mol Cell Biol 2020
139
22

Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase.
Pu Gao, Manuel Ascano, Yang Wu, Winfried Barchet, Barbara L Gaffney, Thomas Zillinger, Artem A Serganov, Yizhou Liu, Roger A Jones, Gunther Hartmann,[...]. Cell 2013
486
22

Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation.
Siqi Liu, Xin Cai, Jiaxi Wu, Qian Cong, Xiang Chen, Tuo Li, Fenghe Du, Junyao Ren, You-Tong Wu, Nick V Grishin,[...]. Science 2015
683
22

Nuclear envelope assembly defects link mitotic errors to chromothripsis.
Shiwei Liu, Mijung Kwon, Mark Mannino, Nachen Yang, Fioranna Renda, Alexey Khodjakov, David Pellman. Nature 2018
120
22

The cytosolic DNA sensor cGAS forms an oligomeric complex with DNA and undergoes switch-like conformational changes in the activation loop.
Xu Zhang, Jiaxi Wu, Fenghe Du, Hui Xu, Lijun Sun, Zhe Chen, Chad A Brautigam, Xuewu Zhang, Zhijian J Chen. Cell Rep 2014
196
22

cGAS suppresses genomic instability as a decelerator of replication forks.
Hao Chen, Hao Chen, Jiamin Zhang, Yumin Wang, Antoine Simoneau, Hui Yang, Arthur S Levine, Lee Zou, Zhijian Chen, Li Lan. Sci Adv 2020
19
31

A Nuclear Export Signal Is Required for cGAS to Sense Cytosolic DNA.
Hong Sun, Yu Huang, Shan Mei, Fengwen Xu, Xiaoman Liu, Fei Zhao, Lijuan Yin, Di Zhang, Liang Wei, Chao Wu,[...]. Cell Rep 2021
12
50


Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation.
Wei Xie, Lodoe Lama, Carolina Adura, Daisuke Tomita, J Fraser Glickman, Thomas Tuschl, Dinshaw J Patel. Proc Natl Acad Sci U S A 2019
39
22

Phosphoinositide Interactions Position cGAS at the Plasma Membrane to Ensure Efficient Distinction between Self- and Viral DNA.
Katherine C Barnett, Julia M Coronas-Serna, Wen Zhou, Michael J Ernandes, Anh Cao, Philip J Kranzusch, Jonathan C Kagan. Cell 2019
77
22

Phosphorylation of cGAS by CDK1 impairs self-DNA sensing in mitosis.
Li Zhong, Ming-Ming Hu, Li-Jun Bian, Ying Liu, Qiang Chen, Hong-Bing Shu. Cell Discov 2020
10
60

cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING.
Andrea Ablasser, Marion Goldeck, Taner Cavlar, Tobias Deimling, Gregor Witte, Ingo Röhl, Karl-Peter Hopfner, Janos Ludwig, Veit Hornung. Nature 2013
713
18

Catastrophic nuclear envelope collapse in cancer cell micronuclei.
Emily M Hatch, Andrew H Fischer, Thomas J Deerinck, Martin W Hetzer. Cell 2013
337
18

Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases.
Daxing Gao, Tuo Li, Xiao-Dong Li, Xiang Chen, Quan-Zhen Li, Mary Wight-Carter, Zhijian J Chen. Proc Natl Acad Sci U S A 2015
306
18

cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection.
Megan H Orzalli, Nicole M Broekema, Benjamin A Diner, Dustin C Hancks, Nels C Elde, Ileana M Cristea, David M Knipe. Proc Natl Acad Sci U S A 2015
153
18

Detection of Microbial Infections Through Innate Immune Sensing of Nucleic Acids.
Xiaojun Tan, Lijun Sun, Jueqi Chen, Zhijian J Chen. Annu Rev Microbiol 2018
157
18

Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA.
Anthony Rongvaux, Ruaidhrí Jackson, Christian C D Harman, Tuo Li, A Phillip West, Marcel R de Zoete, Youtong Wu, Brian Yordy, Saquib A Lakhani, Chia-Yi Kuan,[...]. Cell 2014
383
18

TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells.
Katherine R Balka, Cynthia Louis, Tahnee L Saunders, Amber M Smith, Dale J Calleja, Damian B D'Silva, Fiona Moghaddas, Maximilien Tailler, Kate E Lawlor, Yifan Zhan,[...]. Cell Rep 2020
46
18

SAMHD1 acts at stalled replication forks to prevent interferon induction.
Flavie Coquel, Maria-Joao Silva, Hervé Técher, Karina Zadorozhny, Sushma Sharma, Jadwiga Nieminuszczy, Clément Mettling, Elodie Dardillac, Antoine Barthe, Anne-Lyne Schmitz,[...]. Nature 2018
153
18


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.