Ana Griciuc, Rudolph E Tanzi. Curr Opin Neurol 2021
Times Cited: 44
Times Cited: 44
Times Cited
Times Co-cited
Similarity
Alzheimer's disease risk gene CD33 inhibits microglial uptake of amyloid beta.
Ana Griciuc, Alberto Serrano-Pozo, Antonio R Parrado, Andrea N Lesinski, Caroline N Asselin, Kristina Mullin, Basavaraj Hooli, Se Hoon Choi, Bradley T Hyman, Rudolph E Tanzi. Neuron 2013
Ana Griciuc, Alberto Serrano-Pozo, Antonio R Parrado, Andrea N Lesinski, Caroline N Asselin, Kristina Mullin, Basavaraj Hooli, Se Hoon Choi, Bradley T Hyman, Rudolph E Tanzi. Neuron 2013
25
A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease.
Hadas Keren-Shaul, Amit Spinrad, Assaf Weiner, Orit Matcovitch-Natan, Raz Dvir-Szternfeld, Tyler K Ulland, Eyal David, Kuti Baruch, David Lara-Astaiso, Beata Toth,[...]. Cell 2017
Hadas Keren-Shaul, Amit Spinrad, Assaf Weiner, Orit Matcovitch-Natan, Raz Dvir-Szternfeld, Tyler K Ulland, Eyal David, Kuti Baruch, David Lara-Astaiso, Beata Toth,[...]. Cell 2017
25
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
J C Lambert, C A Ibrahim-Verbaas, D Harold, A C Naj, R Sims, C Bellenguez, A L DeStafano, J C Bis, G W Beecham, B Grenier-Boley,[...]. Nat Genet 2013
J C Lambert, C A Ibrahim-Verbaas, D Harold, A C Naj, R Sims, C Bellenguez, A L DeStafano, J C Bis, G W Beecham, B Grenier-Boley,[...]. Nat Genet 2013
20
TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease.
Tyler K Ulland, Wilbur M Song, Stanley Ching-Cheng Huang, Jason D Ulrich, Alexey Sergushichev, Wandy L Beatty, Alexander A Loboda, Yingyue Zhou, Nigel J Cairns, Amal Kambal,[...]. Cell 2017
Tyler K Ulland, Wilbur M Song, Stanley Ching-Cheng Huang, Jason D Ulrich, Alexey Sergushichev, Wandy L Beatty, Alexander A Loboda, Yingyue Zhou, Nigel J Cairns, Amal Kambal,[...]. Cell 2017
20
Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.
Brian W Kunkle, Benjamin Grenier-Boley, Rebecca Sims, Joshua C Bis, Vincent Damotte, Adam C Naj, Anne Boland, Maria Vronskaya, Sven J van der Lee, Alexandre Amlie-Wolf,[...]. Nat Genet 2019
Brian W Kunkle, Benjamin Grenier-Boley, Rebecca Sims, Joshua C Bis, Vincent Damotte, Adam C Naj, Anne Boland, Maria Vronskaya, Sven J van der Lee, Alexandre Amlie-Wolf,[...]. Nat Genet 2019
18
The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases.
Susanne Krasemann, Charlotte Madore, Ron Cialic, Caroline Baufeld, Narghes Calcagno, Rachid El Fatimy, Lien Beckers, Elaine O'Loughlin, Yang Xu, Zain Fanek,[...]. Immunity 2017
Susanne Krasemann, Charlotte Madore, Ron Cialic, Caroline Baufeld, Narghes Calcagno, Rachid El Fatimy, Lien Beckers, Elaine O'Loughlin, Yang Xu, Zain Fanek,[...]. Immunity 2017
18
18
Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here?
Fangda Leng, Paul Edison. Nat Rev Neurol 2021
Fangda Leng, Paul Edison. Nat Rev Neurol 2021
15
TREM2 variants in Alzheimer's disease.
Rita Guerreiro, Aleksandra Wojtas, Jose Bras, Minerva Carrasquillo, Ekaterina Rogaeva, Elisa Majounie, Carlos Cruchaga, Celeste Sassi, John S K Kauwe, Steven Younkin,[...]. N Engl J Med 2013
Rita Guerreiro, Aleksandra Wojtas, Jose Bras, Minerva Carrasquillo, Ekaterina Rogaeva, Elisa Majounie, Carlos Cruchaga, Celeste Sassi, John S K Kauwe, Steven Younkin,[...]. N Engl J Med 2013
15
Alzheimer's disease risk genes and mechanisms of disease pathogenesis.
Celeste M Karch, Alison M Goate. Biol Psychiatry 2015
Celeste M Karch, Alison M Goate. Biol Psychiatry 2015
13
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
Adam C Naj, Gyungah Jun, Gary W Beecham, Li-San Wang, Badri Narayan Vardarajan, Jacqueline Buros, Paul J Gallins, Joseph D Buxbaum, Gail P Jarvik, Paul K Crane,[...]. Nat Genet 2011
Adam C Naj, Gyungah Jun, Gary W Beecham, Li-San Wang, Badri Narayan Vardarajan, Jacqueline Buros, Paul J Gallins, Joseph D Buxbaum, Gail P Jarvik, Paul K Crane,[...]. Nat Genet 2011
13
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.
Paul Hollingworth, Denise Harold, Rebecca Sims, Amy Gerrish, Jean-Charles Lambert, Minerva M Carrasquillo, Richard Abraham, Marian L Hamshere, Jaspreet Singh Pahwa, Valentina Moskvina,[...]. Nat Genet 2011
Paul Hollingworth, Denise Harold, Rebecca Sims, Amy Gerrish, Jean-Charles Lambert, Minerva M Carrasquillo, Richard Abraham, Marian L Hamshere, Jaspreet Singh Pahwa, Valentina Moskvina,[...]. Nat Genet 2011
13
Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration.
Aleksandra Deczkowska, Hadas Keren-Shaul, Assaf Weiner, Marco Colonna, Michal Schwartz, Ido Amit. Cell 2018
Aleksandra Deczkowska, Hadas Keren-Shaul, Assaf Weiner, Marco Colonna, Michal Schwartz, Ido Amit. Cell 2018
13
TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model.
Yaming Wang, Marina Cella, Kaitlin Mallinson, Jason D Ulrich, Katherine L Young, Michelle L Robinette, Susan Gilfillan, Gokul M Krishnan, Shwetha Sudhakar, Bernd H Zinselmeyer,[...]. Cell 2015
Yaming Wang, Marina Cella, Kaitlin Mallinson, Jason D Ulrich, Katherine L Young, Michelle L Robinette, Susan Gilfillan, Gokul M Krishnan, Shwetha Sudhakar, Bernd H Zinselmeyer,[...]. Cell 2015
13
Variant of TREM2 associated with the risk of Alzheimer's disease.
Thorlakur Jonsson, Hreinn Stefansson, Stacy Steinberg, Ingileif Jonsdottir, Palmi V Jonsson, Jon Snaedal, Sigurbjorn Bjornsson, Johanna Huttenlocher, Allan I Levey, James J Lah,[...]. N Engl J Med 2013
Thorlakur Jonsson, Hreinn Stefansson, Stacy Steinberg, Ingileif Jonsdottir, Palmi V Jonsson, Jon Snaedal, Sigurbjorn Bjornsson, Johanna Huttenlocher, Allan I Levey, James J Lah,[...]. N Engl J Med 2013
13
TREM2 Acts Downstream of CD33 in Modulating Microglial Pathology in Alzheimer's Disease.
Ana Griciuc, Shaun Patel, Anthony N Federico, Se Hoon Choi, Brendan J Innes, Mary K Oram, Gea Cereghetti, Danielle McGinty, Anthony Anselmo, Ruslan I Sadreyev,[...]. Neuron 2019
Ana Griciuc, Shaun Patel, Anthony N Federico, Se Hoon Choi, Brendan J Innes, Mary K Oram, Gea Cereghetti, Danielle McGinty, Anthony Anselmo, Ruslan I Sadreyev,[...]. Neuron 2019
11
TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function.
Yingjun Zhao, Xilin Wu, Xiaoguang Li, Lu-Lin Jiang, Xun Gui, Yan Liu, Yu Sun, Bing Zhu, Juan C Piña-Crespo, Muxian Zhang,[...]. Neuron 2018
Yingjun Zhao, Xilin Wu, Xiaoguang Li, Lu-Lin Jiang, Xun Gui, Yan Liu, Yu Sun, Bing Zhu, Juan C Piña-Crespo, Muxian Zhang,[...]. Neuron 2018
11
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families.
E H Corder, A M Saunders, W J Strittmatter, D E Schmechel, P C Gaskell, G W Small, A D Roses, J L Haines, M A Pericak-Vance. Science 1993
E H Corder, A M Saunders, W J Strittmatter, D E Schmechel, P C Gaskell, G W Small, A D Roses, J L Haines, M A Pericak-Vance. Science 1993
11
TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia.
Felix L Yeh, Yuanyuan Wang, Irene Tom, Lino C Gonzalez, Morgan Sheng. Neuron 2016
Felix L Yeh, Yuanyuan Wang, Irene Tom, Lino C Gonzalez, Morgan Sheng. Neuron 2016
11
Anti-human TREM2 induces microglia proliferation and reduces pathology in an Alzheimer's disease model.
Shoutang Wang, Meer Mustafa, Carla M Yuede, Santiago Viveros Salazar, Philip Kong, Hua Long, Michael Ward, Omer Siddiqui, Robert Paul, Susan Gilfillan,[...]. J Exp Med 2020
Shoutang Wang, Meer Mustafa, Carla M Yuede, Santiago Viveros Salazar, Philip Kong, Hua Long, Michael Ward, Omer Siddiqui, Robert Paul, Susan Gilfillan,[...]. J Exp Med 2020
11
Complement and microglia mediate early synapse loss in Alzheimer mouse models.
Soyon Hong, Victoria F Beja-Glasser, Bianca M Nfonoyim, Arnaud Frouin, Shaomin Li, Saranya Ramakrishnan, Katherine M Merry, Qiaoqiao Shi, Arnon Rosenthal, Ben A Barres,[...]. Science 2016
Soyon Hong, Victoria F Beja-Glasser, Bianca M Nfonoyim, Arnaud Frouin, Shaomin Li, Saranya Ramakrishnan, Katherine M Merry, Qiaoqiao Shi, Arnon Rosenthal, Ben A Barres,[...]. Science 2016
9
The Alzheimer's disease-protective CD33 splice variant mediates adaptive loss of function via diversion to an intracellular pool.
Shoib S Siddiqui, Stevan A Springer, Andrea Verhagen, Venkatasubramaniam Sundaramurthy, Frederico Alisson-Silva, Weiping Jiang, Pradipta Ghosh, Ajit Varki. J Biol Chem 2017
Shoib S Siddiqui, Stevan A Springer, Andrea Verhagen, Venkatasubramaniam Sundaramurthy, Frederico Alisson-Silva, Weiping Jiang, Pradipta Ghosh, Ajit Varki. J Biol Chem 2017
9
Repression of phagocytosis by human CD33 is not conserved with mouse CD33.
Abhishek Bhattacherjee, Emily Rodrigues, Jaesoo Jung, Matthew Luzentales-Simpson, Jhon R Enterina, Danny Galleguillos, Chris D St Laurent, Maryam Nakhaei-Nejad, Felix F Fuchsberger, Laura Streith,[...]. Commun Biol 2019
Abhishek Bhattacherjee, Emily Rodrigues, Jaesoo Jung, Matthew Luzentales-Simpson, Jhon R Enterina, Danny Galleguillos, Chris D St Laurent, Maryam Nakhaei-Nejad, Felix F Fuchsberger, Laura Streith,[...]. Commun Biol 2019
13
Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
Iris E Jansen, Jeanne E Savage, Kyoko Watanabe, Julien Bryois, Dylan M Williams, Stacy Steinberg, Julia Sealock, Ida K Karlsson, Sara Hägg, Lavinia Athanasiu,[...]. Nat Genet 2019
Iris E Jansen, Jeanne E Savage, Kyoko Watanabe, Julien Bryois, Dylan M Williams, Stacy Steinberg, Julia Sealock, Ida K Karlsson, Sara Hägg, Lavinia Athanasiu,[...]. Nat Genet 2019
9
TREM2 sustains microglial expansion during aging and response to demyelination.
Pietro Luigi Poliani, Yaming Wang, Elena Fontana, Michelle L Robinette, Yoshinori Yamanishi, Susan Gilfillan, Marco Colonna. J Clin Invest 2015
Pietro Luigi Poliani, Yaming Wang, Elena Fontana, Michelle L Robinette, Yoshinori Yamanishi, Susan Gilfillan, Marco Colonna. J Clin Invest 2015
9
Deletion of Alzheimer's disease-associated CD33 results in an inflammatory human microglia phenotype.
Jannis Wißfeld, Ichiro Nozaki, Mona Mathews, Tamara Raschka, Christian Ebeling, Veit Hornung, Oliver Brüstle, Harald Neumann. Glia 2021
Jannis Wißfeld, Ichiro Nozaki, Mona Mathews, Tamara Raschka, Christian Ebeling, Veit Hornung, Oliver Brüstle, Harald Neumann. Glia 2021
13
TREM2 - a key player in microglial biology and Alzheimer disease.
Tyler K Ulland, Marco Colonna. Nat Rev Neurol 2018
Tyler K Ulland, Marco Colonna. Nat Rev Neurol 2018
9
Small Molecule Binding to Alzheimer Risk Factor CD33 Promotes Aβ Phagocytosis.
Luke A Miles, Stefan J Hermans, Gabriela A N Crespi, Jonathan H Gooi, Larissa Doughty, Tracy L Nero, Jasmina Markulić, Andreas Ebneth, Berthold Wroblowski, Daniel Oehlrich,[...]. iScience 2019
Luke A Miles, Stefan J Hermans, Gabriela A N Crespi, Jonathan H Gooi, Larissa Doughty, Tracy L Nero, Jasmina Markulić, Andreas Ebneth, Berthold Wroblowski, Daniel Oehlrich,[...]. iScience 2019
11
Gene therapy for Alzheimer's disease targeting CD33 reduces amyloid beta accumulation and neuroinflammation.
Ana Griciuc, Anthony N Federico, Jeyashree Natasan, Angela M Forte, Danielle McGinty, Huong Nguyen, Adrienn Volak, Stanley LeRoy, Sheetal Gandhi, Eli P Lerner,[...]. Hum Mol Genet 2020
Ana Griciuc, Anthony N Federico, Jeyashree Natasan, Angela M Forte, Danielle McGinty, Huong Nguyen, Adrienn Volak, Stanley LeRoy, Sheetal Gandhi, Eli P Lerner,[...]. Hum Mol Genet 2020
15
Elucidating the Role of TREM2 in Alzheimer's Disease.
Jason D Ulrich, Tyler K Ulland, Marco Colonna, David M Holtzman. Neuron 2017
Jason D Ulrich, Tyler K Ulland, Marco Colonna, David M Holtzman. Neuron 2017
9
Alzheimer's disease genetics: from the bench to the clinic.
Celeste M Karch, Carlos Cruchaga, Alison M Goate. Neuron 2014
Celeste M Karch, Carlos Cruchaga, Alison M Goate. Neuron 2014
9
TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques.
Yaming Wang, Tyler K Ulland, Jason D Ulrich, Wilbur Song, John A Tzaferis, Justin T Hole, Peng Yuan, Thomas E Mahan, Yang Shi, Susan Gilfillan,[...]. J Exp Med 2016
Yaming Wang, Tyler K Ulland, Jason D Ulrich, Wilbur Song, John A Tzaferis, Justin T Hole, Peng Yuan, Thomas E Mahan, Yang Shi, Susan Gilfillan,[...]. J Exp Med 2016
9
Sequential proteolytic processing of the triggering receptor expressed on myeloid cells-2 (TREM2) protein by ectodomain shedding and γ-secretase-dependent intramembranous cleavage.
Patrick Wunderlich, Konstantin Glebov, Nadja Kemmerling, Nguyen T Tien, Harald Neumann, Jochen Walter. J Biol Chem 2013
Patrick Wunderlich, Konstantin Glebov, Nadja Kemmerling, Nguyen T Tien, Harald Neumann, Jochen Walter. J Biol Chem 2013
9
Alzheimer's disease: the challenge of the second century.
David M Holtzman, John C Morris, Alison M Goate. Sci Transl Med 2011
David M Holtzman, John C Morris, Alison M Goate. Sci Transl Med 2011
9
Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2).
Yuka Atagi, Chia-Chen Liu, Meghan M Painter, Xiao-Fen Chen, Christophe Verbeeck, Honghua Zheng, Xia Li, Rosa Rademakers, Silvia S Kang, Huaxi Xu,[...]. J Biol Chem 2015
Yuka Atagi, Chia-Chen Liu, Meghan M Painter, Xiao-Fen Chen, Christophe Verbeeck, Honghua Zheng, Xia Li, Rosa Rademakers, Silvia S Kang, Huaxi Xu,[...]. J Biol Chem 2015
9
Soluble TREM2 induces inflammatory responses and enhances microglial survival.
Li Zhong, Xiao-Fen Chen, Tingting Wang, Zhe Wang, Chunyan Liao, Zongqi Wang, Ruizhi Huang, Daxin Wang, Xinxiu Li, Linbei Wu,[...]. J Exp Med 2017
Li Zhong, Xiao-Fen Chen, Tingting Wang, Zhe Wang, Chunyan Liao, Zongqi Wang, Ruizhi Huang, Daxin Wang, Xinxiu Li, Linbei Wu,[...]. J Exp Med 2017
9
The amyloid hypothesis of Alzheimer's disease at 25 years.
Dennis J Selkoe, John Hardy. EMBO Mol Med 2016
Dennis J Selkoe, John Hardy. EMBO Mol Med 2016
9
Alzheimer's Disease Genetics: A Dampened Microglial Response?
Zena K Chatila, Elizabeth M Bradshaw. Neuroscientist 2021
Zena K Chatila, Elizabeth M Bradshaw. Neuroscientist 2021
50
TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy.
Peng Yuan, Carlo Condello, C Dirk Keene, Yaming Wang, Thomas D Bird, Steven M Paul, Wenjie Luo, Marco Colonna, David Baddeley, Jaime Grutzendler. Neuron 2016
Peng Yuan, Carlo Condello, C Dirk Keene, Yaming Wang, Thomas D Bird, Steven M Paul, Wenjie Luo, Marco Colonna, David Baddeley, Jaime Grutzendler. Neuron 2016
9
Role of pro-inflammatory cytokines released from microglia in Alzheimer's disease.
Wen-Ying Wang, Meng-Shan Tan, Jin-Tai Yu, Lan Tan. Ann Transl Med 2015
Wen-Ying Wang, Meng-Shan Tan, Jin-Tai Yu, Lan Tan. Ann Transl Med 2015
9
Alzheimer's disease.
Philip Scheltens, Bart De Strooper, Miia Kivipelto, Henne Holstege, Gael Chételat, Charlotte E Teunissen, Jeffrey Cummings, Wiesje M van der Flier. Lancet 2021
Philip Scheltens, Bart De Strooper, Miia Kivipelto, Henne Holstege, Gael Chételat, Charlotte E Teunissen, Jeffrey Cummings, Wiesje M van der Flier. Lancet 2021
9
9
9
Neuroinflammation in Alzheimer's disease.
Michael T Heneka, Monica J Carson, Joseph El Khoury, Gary E Landreth, Frederic Brosseron, Douglas L Feinstein, Andreas H Jacobs, Tony Wyss-Coray, Javier Vitorica, Richard M Ransohoff,[...]. Lancet Neurol 2015
Michael T Heneka, Monica J Carson, Joseph El Khoury, Gary E Landreth, Frederic Brosseron, Douglas L Feinstein, Andreas H Jacobs, Tony Wyss-Coray, Javier Vitorica, Richard M Ransohoff,[...]. Lancet Neurol 2015
9
Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer's disease progression.
Xinyi Wang, Guangqiang Sun, Teng Feng, Jing Zhang, Xun Huang, Tao Wang, Zuoquan Xie, Xingkun Chu, Jun Yang, Huan Wang,[...]. Cell Res 2019
Xinyi Wang, Guangqiang Sun, Teng Feng, Jing Zhang, Xun Huang, Tao Wang, Zuoquan Xie, Xingkun Chu, Jun Yang, Huan Wang,[...]. Cell Res 2019
9
Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease.
Bin Zhang, Chris Gaiteri, Liviu-Gabriel Bodea, Zhi Wang, Joshua McElwee, Alexei A Podtelezhnikov, Chunsheng Zhang, Tao Xie, Linh Tran, Radu Dobrin,[...]. Cell 2013
Bin Zhang, Chris Gaiteri, Liviu-Gabriel Bodea, Zhi Wang, Joshua McElwee, Alexei A Podtelezhnikov, Chunsheng Zhang, Tao Xie, Linh Tran, Radu Dobrin,[...]. Cell 2013
6
Late onset Alzheimer's disease genetics implicates microglial pathways in disease risk.
Anastasia G Efthymiou, Alison M Goate. Mol Neurodegener 2017
Anastasia G Efthymiou, Alison M Goate. Mol Neurodegener 2017
6
CD33 modulates TREM2: convergence of Alzheimer loci.
Gail Chan, Charles C White, Phoebe A Winn, Maria Cimpean, Joseph M Replogle, Laura R Glick, Nicole E Cuerdon, Katie J Ryan, Keith A Johnson, Julie A Schneider,[...]. Nat Neurosci 2015
Gail Chan, Charles C White, Phoebe A Winn, Maria Cimpean, Joseph M Replogle, Laura R Glick, Nicole E Cuerdon, Katie J Ryan, Keith A Johnson, Julie A Schneider,[...]. Nat Neurosci 2015
6
Evaluation of CD33 as a genetic risk factor for Alzheimer's disease.
Steven Estus, Benjamin C Shaw, Nicholas Devanney, Yuriko Katsumata, Eileen E Press, David W Fardo. Acta Neuropathol 2019
Steven Estus, Benjamin C Shaw, Nicholas Devanney, Yuriko Katsumata, Eileen E Press, David W Fardo. Acta Neuropathol 2019
6
CD33 Alzheimer's risk-altering polymorphism, CD33 expression, and exon 2 splicing.
Manasi Malik, James F Simpson, Ishita Parikh, Bernard R Wilfred, David W Fardo, Peter T Nelson, Steven Estus. J Neurosci 2013
Manasi Malik, James F Simpson, Ishita Parikh, Bernard R Wilfred, David W Fardo, Peter T Nelson, Steven Estus. J Neurosci 2013
6
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.