A citation-based method for searching scientific literature

Roberta Zappasodi, Inna Serganova, Ivan J Cohen, Masatomo Maeda, Masahiro Shindo, Yasin Senbabaoglu, McLane J Watson, Avigdor Leftin, Rachana Maniyar, Svena Verma, Matthew Lubin, Myat Ko, Mayuresh M Mane, Hong Zhong, Cailian Liu, Arnab Ghosh, Mohsen Abu-Akeel, Ellen Ackerstaff, Jason A Koutcher, Ping-Chih Ho, Greg M Delgoffe, Ronald Blasberg, Jedd D Wolchok, Taha Merghoub. Nature 2021
Times Cited: 28







List of co-cited articles
342 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Metabolic support of tumour-infiltrating regulatory T cells by lactic acid.
McLane J Watson, Paolo D A Vignali, Steven J Mullett, Abigail E Overacre-Delgoffe, Ronal M Peralta, Stephanie Grebinoski, Ashley V Menk, Natalie L Rittenhouse, Kristin DePeaux, Ryan D Whetstone,[...]. Nature 2021
56
60

Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments.
Alessia Angelin, Luis Gil-de-Gómez, Satinder Dahiya, Jing Jiao, Lili Guo, Matthew H Levine, Zhonglin Wang, William J Quinn, Piotr K Kopinski, Liqing Wang,[...]. Cell Metab 2017
353
35

The CD28 signaling pathway regulates glucose metabolism.
Kenneth A Frauwirth, James L Riley, Marian H Harris, Richard V Parry, Jeffrey C Rathmell, David R Plas, Rebecca L Elstrom, Carl H June, Craig B Thompson. Immunity 2002
869
32

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression.
Chih-Hao Chang, Jing Qiu, David O'Sullivan, Michael D Buck, Takuro Noguchi, Jonathan D Curtis, Qiongyu Chen, Mariel Gindin, Matthew M Gubin, Gerritje J W van der Windt,[...]. Cell 2015
32

Fatty acid metabolism complements glycolysis in the selective regulatory T cell expansion during tumor growth.
Ilenia Pacella, Claudio Procaccini, Chiara Focaccetti, Stefano Miacci, Eleonora Timperi, Deriggio Faicchia, Martina Severa, Fabiana Rizzo, Eliana Marina Coccia, Fabrizia Bonacina,[...]. Proc Natl Acad Sci U S A 2018
107
25

Mitochondrial complex III is essential for suppressive function of regulatory T cells.
Samuel E Weinberg, Benjamin D Singer, Elizabeth M Steinert, Carlos A Martinez, Manan M Mehta, Inmaculada Martínez-Reyes, Peng Gao, Kathryn A Helmin, Hiam Abdala-Valencia, Laura A Sena,[...]. Nature 2019
150
25

LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells.
Almut Brand, Katrin Singer, Gudrun E Koehl, Marlene Kolitzus, Gabriele Schoenhammer, Annette Thiel, Carina Matos, Christina Bruss, Sebastian Klobuch, Katrin Peter,[...]. Cell Metab 2016
530
25

Lipid signalling enforces functional specialization of Treg cells in tumours.
Seon Ah Lim, Jun Wei, Thanh-Long M Nguyen, Hao Shi, Wei Su, Gustavo Palacios, Yogesh Dhungana, Nicole M Chapman, Lingyun Long, Jordy Saravia,[...]. Nature 2021
24
29

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
25

Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.
Ping-Chih Ho, Jessica Dauz Bihuniak, Andrew N Macintyre, Matthew Staron, Xiaojing Liu, Robert Amezquita, Yao-Chen Tsui, Guoliang Cui, Goran Micevic, Jose C Perales,[...]. Cell 2015
662
21

Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.
Ryan D Michalek, Valerie A Gerriets, Sarah R Jacobs, Andrew N Macintyre, Nancie J MacIver, Emily F Mason, Sarah A Sullivan, Amanda G Nichols, Jeffrey C Rathmell. J Immunol 2011
21

CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors.
Haiping Wang, Fabien Franco, Yao-Chen Tsui, Xin Xie, Marcel P Trefny, Roberta Zappasodi, Syed Raza Mohmood, Juan Fernández-García, Chin-Hsien Tsai, Isabell Schulze,[...]. Nat Immunol 2020
97
21

Understanding the Warburg effect: the metabolic requirements of cell proliferation.
Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
21

Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy.
Tina Cascone, Jodi A McKenzie, Rina M Mbofung, Simone Punt, Zhe Wang, Chunyu Xu, Leila J Williams, Zhiqiang Wang, Christopher A Bristow, Alessandro Carugo,[...]. Cell Metab 2018
198
17

Inhibitory effect of tumor cell-derived lactic acid on human T cells.
Karin Fischer, Petra Hoffmann, Simon Voelkl, Norbert Meidenbauer, Julia Ammer, Matthias Edinger, Eva Gottfried, Sabine Schwarz, Gregor Rothe, Sabine Hoves,[...]. Blood 2007
849
17

Glutamine-dependent α-ketoglutarate production regulates the balance between T helper 1 cell and regulatory T cell generation.
Dorota Klysz, Xuguang Tai, Philippe A Robert, Marco Craveiro, Gaspard Cretenet, Leal Oburoglu, Cédric Mongellaz, Stefan Floess, Vanessa Fritz, Maria I Matias,[...]. Sci Signal 2015
211
17

Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression.
Valerie A Gerriets, Rigel J Kishton, Marc O Johnson, Sivan Cohen, Peter J Siska, Amanda G Nichols, Marc O Warmoes, Aguirre A de Cubas, Nancie J MacIver, Jason W Locasale,[...]. Nat Immunol 2016
239
17

Control of regulatory T cell development by the transcription factor Foxp3.
Shohei Hori, Takashi Nomura, Shimon Sakaguchi. Science 2003
17

PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation.
Nikolaos Patsoukis, Kankana Bardhan, Pranam Chatterjee, Duygu Sari, Bianling Liu, Lauren N Bell, Edward D Karoly, Gordon J Freeman, Victoria Petkova, Pankaj Seth,[...]. Nat Commun 2015
494
14

Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion.
Robert D Leone, Liang Zhao, Judson M Englert, Im-Meng Sun, Min-Hee Oh, Im-Hong Sun, Matthew L Arwood, Ian A Bettencourt, Chirag H Patel, Jiayu Wen,[...]. Science 2019
215
14

Efficacy of PD-1 Blockade Is Potentiated by Metformin-Induced Reduction of Tumor Hypoxia.
Nicole E Scharping, Ashley V Menk, Ryan D Whetstone, Xue Zeng, Greg M Delgoffe. Cancer Immunol Res 2017
202
14


Inflammatory T cell responses rely on amino acid transporter ASCT2 facilitation of glutamine uptake and mTORC1 kinase activation.
Mako Nakaya, Yichuan Xiao, Xiaofei Zhou, Jae-Hoon Chang, Mikyoung Chang, Xuhong Cheng, Marzenna Blonska, Xin Lin, Shao-Cong Sun. Immunity 2014
391
14

Homeostatic control of metabolic and functional fitness of Treg cells by LKB1 signalling.
Kai Yang, Daniel Bastardo Blanco, Geoffrey Neale, Peter Vogel, Julian Avila, Clary B Clish, Chuan Wu, Sharad Shrestha, Sherri Rankin, Lingyun Long,[...]. Nature 2017
97
14

HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells.
Lewis Z Shi, Ruoning Wang, Gonghua Huang, Peter Vogel, Geoffrey Neale, Douglas R Green, Hongbo Chi. J Exp Med 2011
14

The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation.
Ruoning Wang, Christopher P Dillon, Lewis Zhichang Shi, Sandra Milasta, Robert Carter, David Finkelstein, Laura L McCormick, Patrick Fitzgerald, Hongbo Chi, Joshua Munger,[...]. Immunity 2011
14

Immunometabolism of regulatory T cells.
Ryan Newton, Bhavana Priyadharshini, Laurence A Turka. Nat Immunol 2016
173
14

Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism.
Marc O Johnson, Melissa M Wolf, Matthew Z Madden, Gabriela Andrejeva, Ayaka Sugiura, Diana C Contreras, Damian Maseda, Maria V Liberti, Katelyn Paz, Rigel J Kishton,[...]. Cell 2018
188
14

Cancer SLC43A2 alters T cell methionine metabolism and histone methylation.
Yingjie Bian, Wei Li, Daniel M Kremer, Peter Sajjakulnukit, Shasha Li, Joel Crespo, Zeribe C Nwosu, Li Zhang, Arkadiusz Czerwonka, Anna Pawłowska,[...]. Nature 2020
63
14

Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion.
Nicole E Scharping, Dayana B Rivadeneira, Ashley V Menk, Paolo D A Vignali, B Rhodes Ford, Natalie L Rittenhouse, Ronal Peralta, Yiyang Wang, Yupeng Wang, Kristin DePeaux,[...]. Nat Immunol 2021
54
14

An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells.
Joshua D Mezrich, John H Fechner, Xiaoji Zhang, Brian P Johnson, William J Burlingham, Christopher A Bradfield. J Immunol 2010
820
14

Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate.
Ye Zheng, Steven Josefowicz, Ashutosh Chaudhry, Xiao P Peng, Katherine Forbush, Alexander Y Rudensky. Nature 2010
777
14

Metabolic control of regulatory T cell (Treg) survival and function by Lkb1.
Nanhai He, Weiwei Fan, Brian Henriquez, Ruth T Yu, Annette R Atkins, Christopher Liddle, Ye Zheng, Michael Downes, Ronald M Evans. Proc Natl Acad Sci U S A 2017
71
14

Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells.
Omkar U Kawalekar, Roddy S O'Connor, Joseph A Fraietta, Lili Guo, Shannon E McGettigan, Avery D Posey, Prachi R Patel, Sonia Guedan, John Scholler, Brian Keith,[...]. Immunity 2016
431
10

Neutralization of Tumor Acidity Improves Antitumor Responses to Immunotherapy.
Shari Pilon-Thomas, Krithika N Kodumudi, Asmaa E El-Kenawi, Shonagh Russell, Amy M Weber, Kimberly Luddy, Mehdi Damaghi, Jonathan W Wojtkowiak, James J Mulé, Arig Ibrahim-Hashim,[...]. Cancer Res 2016
248
10

Aerobic glycolysis promotes T helper 1 cell differentiation through an epigenetic mechanism.
Min Peng, Na Yin, Sagar Chhangawala, Ke Xu, Christina S Leslie, Ming O Li. Science 2016
318
10

Cholesterol Induces CD8+ T Cell Exhaustion in the Tumor Microenvironment.
Xingzhe Ma, Enguang Bi, Yong Lu, Pan Su, Chunjian Huang, Lintao Liu, Qiang Wang, Maojie Yang, Matthew F Kalady, Jianfei Qian,[...]. Cell Metab 2019
140
10

Disturbed mitochondrial dynamics in CD8+ TILs reinforce T cell exhaustion.
Yi-Ru Yu, Hana Imrichova, Haiping Wang, Tung Chao, Zhengtao Xiao, Min Gao, Marcela Rincon-Restrepo, Fabien Franco, Raphael Genolet, Wan-Chen Cheng,[...]. Nat Immunol 2020
51
10

Lactate modulates CD4+ T-cell polarization and induces an immunosuppressive environment, which sustains prostate carcinoma progression via TLR8/miR21 axis.
G Comito, A Iscaro, M Bacci, A Morandi, L Ippolito, M Parri, I Montagnani, M R Raspollini, S Serni, L Simeoni,[...]. Oncogene 2019
56
10

Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche.
David Clever, Rahul Roychoudhuri, Michael G Constantinides, Michael H Askenase, Madhusudhanan Sukumar, Christopher A Klebanoff, Robert L Eil, Heather D Hickman, Zhiya Yu, Jenny H Pan,[...]. Cell 2016
126
10

The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction.
Nicole E Scharping, Ashley V Menk, Rebecca S Moreci, Ryan D Whetstone, Rebekah E Dadey, Simon C Watkins, Robert L Ferris, Greg M Delgoffe. Immunity 2016
259
10

Extracellular adenosine-mediated modulation of regulatory T cells.
Akio Ohta, Michail Sitkovsky. Front Immunol 2014
146
10

Posttranscriptional control of T cell effector function by aerobic glycolysis.
Chih-Hao Chang, Jonathan D Curtis, Leonard B Maggi, Brandon Faubert, Alejandro V Villarino, David O'Sullivan, Stanley Ching-Cheng Huang, Gerritje J W van der Windt, Julianna Blagih, Jing Qiu,[...]. Cell 2013
10

CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms.
Richard V Parry, Jens M Chemnitz, Kenneth A Frauwirth, Anthony R Lanfranco, Inbal Braunstein, Sumire V Kobayashi, Peter S Linsley, Craig B Thompson, James L Riley. Mol Cell Biol 2005
10

Metabolic control of TH17 and induced Treg cell balance by an epigenetic mechanism.
Tao Xu, Kelly M Stewart, Xiaohu Wang, Kai Liu, Min Xie, Jae Kyu Ryu, Ke Li, Tianhua Ma, Haixia Wang, Lu Ni,[...]. Nature 2017
142
10

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation.
Nicholas Arpaia, Clarissa Campbell, Xiying Fan, Stanislav Dikiy, Joris van der Veeken, Paul deRoos, Hui Liu, Justin R Cross, Klaus Pfeffer, Paul J Coffer,[...]. Nature 2013
10

Transcription factors Foxo3a and Foxo1 couple the E3 ligase Cbl-b to the induction of Foxp3 expression in induced regulatory T cells.
Yohsuke Harada, Yasuyo Harada, Chris Elly, Ge Ying, Ji-Hye Paik, Ronald A DePinho, Yun-Cai Liu. J Exp Med 2010
206
10

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells.
Yukihiro Furusawa, Yuuki Obata, Shinji Fukuda, Takaho A Endo, Gaku Nakato, Daisuke Takahashi, Yumiko Nakanishi, Chikako Uetake, Keiko Kato, Tamotsu Kato,[...]. Nature 2013
10

Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability.
Mark R Sullivan, Laura V Danai, Caroline A Lewis, Sze Ham Chan, Dan Y Gui, Tenzin Kunchok, Emily A Dennstedt, Matthew G Vander Heiden, Alexander Muir. Elife 2019
138
10

Regulatory T cells: mechanisms of differentiation and function.
Steven Z Josefowicz, Li-Fan Lu, Alexander Y Rudensky. Annu Rev Immunol 2012
10


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.