Olubankole Aladesuyi Arogundade, Sandra Nguyen, Ringo Leung, Danielle Wainio, Maria Rodriguez, John Ravits. Acta Neuropathol Commun 2021
Times Cited: 4
Times Cited: 4
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The nucleolus functions as a phase-separated protein quality control compartment.
F Frottin, F Schueder, S Tiwary, R Gupta, R Körner, T Schlichthaerle, J Cox, R Jungmann, F U Hartl, M S Hipp. Science 2019
F Frottin, F Schueder, S Tiwary, R Gupta, R Körner, T Schlichthaerle, J Cox, R Jungmann, F U Hartl, M S Hipp. Science 2019
50
FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions.
Seema Qamar, GuoZhen Wang, Suzanne J Randle, Francesco Simone Ruggeri, Juan A Varela, Julie Qiaojin Lin, Emma C Phillips, Akinori Miyashita, Declan Williams, Florian Ströhl,[...]. Cell 2018
Seema Qamar, GuoZhen Wang, Suzanne J Randle, Francesco Simone Ruggeri, Juan A Varela, Julie Qiaojin Lin, Emma C Phillips, Akinori Miyashita, Declan Williams, Florian Ströhl,[...]. Cell 2018
50
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation.
Avinash Patel, Hyun O Lee, Louise Jawerth, Shovamayee Maharana, Marcus Jahnel, Marco Y Hein, Stoyno Stoynov, Julia Mahamid, Shambaditya Saha, Titus M Franzmann,[...]. Cell 2015
Avinash Patel, Hyun O Lee, Louise Jawerth, Shovamayee Maharana, Marcus Jahnel, Marco Y Hein, Stoyno Stoynov, Julia Mahamid, Shambaditya Saha, Titus M Franzmann,[...]. Cell 2015
50
RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43.
Jacob R Mann, Amanda M Gleixner, Jocelyn C Mauna, Edward Gomes, Michael R DeChellis-Marks, Patrick G Needham, Katie E Copley, Bryan Hurtle, Bede Portz, Noah J Pyles,[...]. Neuron 2019
Jacob R Mann, Amanda M Gleixner, Jocelyn C Mauna, Edward Gomes, Michael R DeChellis-Marks, Patrick G Needham, Katie E Copley, Bryan Hurtle, Bede Portz, Noah J Pyles,[...]. Neuron 2019
50
Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death.
Fatima Gasset-Rosa, Shan Lu, Haiyang Yu, Cong Chen, Ze'ev Melamed, Lin Guo, James Shorter, Sandrine Da Cruz, Don W Cleveland. Neuron 2019
Fatima Gasset-Rosa, Shan Lu, Haiyang Yu, Cong Chen, Ze'ev Melamed, Lin Guo, James Shorter, Sandrine Da Cruz, Don W Cleveland. Neuron 2019
50
Phase separation by low complexity domains promotes stress granule assembly and drives pathological fibrillization.
Amandine Molliex, Jamshid Temirov, Jihun Lee, Maura Coughlin, Anderson P Kanagaraj, Hong Joo Kim, Tanja Mittag, J Paul Taylor. Cell 2015
Amandine Molliex, Jamshid Temirov, Jihun Lee, Maura Coughlin, Anderson P Kanagaraj, Hong Joo Kim, Tanja Mittag, J Paul Taylor. Cell 2015
50
Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites.
Takuya Yoshizawa, Rustam Ali, Jenny Jiou, Ho Yee Joyce Fung, Kathleen A Burke, Seung Joong Kim, Yuan Lin, William B Peeples, Daniel Saltzberg, Michael Soniat,[...]. Cell 2018
Takuya Yoshizawa, Rustam Ali, Jenny Jiou, Ho Yee Joyce Fung, Kathleen A Burke, Seung Joong Kim, Yuan Lin, William B Peeples, Daniel Saltzberg, Michael Soniat,[...]. Cell 2018
50
The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease.
Oliver D King, Aaron D Gitler, James Shorter. Brain Res 2012
Oliver D King, Aaron D Gitler, James Shorter. Brain Res 2012
50
Chronic optogenetic induction of stress granules is cytotoxic and reveals the evolution of ALS-FTD pathology.
Peipei Zhang, Baochang Fan, Peiguo Yang, Jamshid Temirov, James Messing, Hong Joo Kim, J Paul Taylor. Elife 2019
Peipei Zhang, Baochang Fan, Peiguo Yang, Jamshid Temirov, James Messing, Hong Joo Kim, J Paul Taylor. Elife 2019
50
Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis.
Sami J Barmada, Gaia Skibinski, Erica Korb, Elizabeth J Rao, Jane Y Wu, Steven Finkbeiner. J Neurosci 2010
Sami J Barmada, Gaia Skibinski, Erica Korb, Elizabeth J Rao, Jane Y Wu, Steven Finkbeiner. J Neurosci 2010
50
C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles.
Kyung-Ha Lee, Peipei Zhang, Hong Joo Kim, Diana M Mitrea, Mohona Sarkar, Brian D Freibaum, Jaclyn Cika, Maura Coughlin, James Messing, Amandine Molliex,[...]. Cell 2016
Kyung-Ha Lee, Peipei Zhang, Hong Joo Kim, Diana M Mitrea, Mohona Sarkar, Brian D Freibaum, Jaclyn Cika, Maura Coughlin, James Messing, Amandine Molliex,[...]. Cell 2016
50
Molecular dissection of amyloid disaggregation by human HSP70.
Anne S Wentink, Nadinath B Nillegoda, Jennifer Feufel, Gabrielė Ubartaitė, Carolyn P Schneider, Paolo De Los Rios, Janosch Hennig, Alessandro Barducci, Bernd Bukau. Nature 2020
Anne S Wentink, Nadinath B Nillegoda, Jennifer Feufel, Gabrielė Ubartaitė, Carolyn P Schneider, Paolo De Los Rios, Janosch Hennig, Alessandro Barducci, Bernd Bukau. Nature 2020
25
Therapeutic Dissolution of Aberrant Phases by Nuclear-Import Receptors.
Lin Guo, Charlotte M Fare, James Shorter. Trends Cell Biol 2019
Lin Guo, Charlotte M Fare, James Shorter. Trends Cell Biol 2019
25
TRIM11 Prevents and Reverses Protein Aggregation and Rescues a Mouse Model of Parkinson's Disease.
Guixin Zhu, Dilshan S Harischandra, Shivani Ghaisas, Pengfei Zhang, Wil Prall, Liangqian Huang, Chantal Maghames, Lili Guo, Esteban Luna, Korrie L Mack,[...]. Cell Rep 2020
Guixin Zhu, Dilshan S Harischandra, Shivani Ghaisas, Pengfei Zhang, Wil Prall, Liangqian Huang, Chantal Maghames, Lili Guo, Esteban Luna, Korrie L Mack,[...]. Cell Rep 2020
25
Expression of therapeutic proteins after delivery of chemically modified mRNA in mice.
Michael S D Kormann, Günther Hasenpusch, Manish K Aneja, Gabriela Nica, Andreas W Flemmer, Susanne Herber-Jonat, Marceline Huppmann, Lauren E Mays, Marta Illenyi, Andrea Schams,[...]. Nat Biotechnol 2011
Michael S D Kormann, Günther Hasenpusch, Manish K Aneja, Gabriela Nica, Andreas W Flemmer, Susanne Herber-Jonat, Marceline Huppmann, Lauren E Mays, Marta Illenyi, Andrea Schams,[...]. Nat Biotechnol 2011
25
Skd3 (human ClpB) is a potent mitochondrial protein disaggregase that is inactivated by 3-methylglutaconic aciduria-linked mutations.
Ryan R Cupo, James Shorter. Elife 2020
Ryan R Cupo, James Shorter. Elife 2020
25
Development of vaccines and antivirals for combating viral pandemics.
Norbert Pardi, Drew Weissman. Nat Biomed Eng 2020
Norbert Pardi, Drew Weissman. Nat Biomed Eng 2020
25
25
Reversing a model of Parkinson's disease with in situ converted nigral neurons.
Hao Qian, Xinjiang Kang, Jing Hu, Dongyang Zhang, Zhengyu Liang, Fan Meng, Xuan Zhang, Yuanchao Xue, Roy Maimon, Steven F Dowdy,[...]. Nature 2020
Hao Qian, Xinjiang Kang, Jing Hu, Dongyang Zhang, Zhengyu Liang, Fan Meng, Xuan Zhang, Yuanchao Xue, Roy Maimon, Steven F Dowdy,[...]. Nature 2020
25
Potentiated Hsp104 variants suppress toxicity of diverse neurodegenerative disease-linked proteins.
Meredith E Jackrel, James Shorter. Dis Model Mech 2014
Meredith E Jackrel, James Shorter. Dis Model Mech 2014
25
Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization.
Leeanne McGurk, Edward Gomes, Lin Guo, Jelena Mojsilovic-Petrovic, Van Tran, Robert G Kalb, James Shorter, Nancy M Bonini. Mol Cell 2018
Leeanne McGurk, Edward Gomes, Lin Guo, Jelena Mojsilovic-Petrovic, Van Tran, Robert G Kalb, James Shorter, Nancy M Bonini. Mol Cell 2018
25
TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD.
Ching-Chieh Chou, Yi Zhang, Mfon E Umoh, Spencer W Vaughan, Ileana Lorenzini, Feilin Liu, Melissa Sayegh, Paul G Donlin-Asp, Yu Han Chen, Duc M Duong,[...]. Nat Neurosci 2018
Ching-Chieh Chou, Yi Zhang, Mfon E Umoh, Spencer W Vaughan, Ileana Lorenzini, Feilin Liu, Melissa Sayegh, Paul G Donlin-Asp, Yu Han Chen, Duc M Duong,[...]. Nat Neurosci 2018
25
25
RNA buffers the phase separation behavior of prion-like RNA binding proteins.
Shovamayee Maharana, Jie Wang, Dimitrios K Papadopoulos, Doris Richter, Andrey Pozniakovsky, Ina Poser, Marc Bickle, Sandra Rizk, Jordina Guillén-Boixet, Titus M Franzmann,[...]. Science 2018
Shovamayee Maharana, Jie Wang, Dimitrios K Papadopoulos, Doris Richter, Andrey Pozniakovsky, Ina Poser, Marc Bickle, Sandra Rizk, Jordina Guillén-Boixet, Titus M Franzmann,[...]. Science 2018
25
Hsp110 mitigates α-synuclein pathology in vivo.
Yumiko V Taguchi, Erica L Gorenberg, Maria Nagy, Drake Thrasher, Wayne A Fenton, Laura Volpicelli-Daley, Arthur L Horwich, Sreeganga S Chandra. Proc Natl Acad Sci U S A 2019
Yumiko V Taguchi, Erica L Gorenberg, Maria Nagy, Drake Thrasher, Wayne A Fenton, Laura Volpicelli-Daley, Arthur L Horwich, Sreeganga S Chandra. Proc Natl Acad Sci U S A 2019
25
The mammalian disaggregase machinery: Hsp110 synergizes with Hsp70 and Hsp40 to catalyze protein disaggregation and reactivation in a cell-free system.
James Shorter. PLoS One 2011
James Shorter. PLoS One 2011
25
Spiraling in Control: Structures and Mechanisms of the Hsp104 Disaggregase.
James Shorter, Daniel R Southworth. Cold Spring Harb Perspect Biol 2019
James Shorter, Daniel R Southworth. Cold Spring Harb Perspect Biol 2019
25
The HSP110/HSP70 disaggregation system generates spreading-competent toxic α-synuclein species.
Jessica Tittelmeier, Carl Alexander Sandhof, Heidrun Maja Ries, Silke Druffel-Augustin, Axel Mogk, Bernd Bukau, Carmen Nussbaum-Krammer. EMBO J 2020
Jessica Tittelmeier, Carl Alexander Sandhof, Heidrun Maja Ries, Silke Druffel-Augustin, Axel Mogk, Bernd Bukau, Carmen Nussbaum-Krammer. EMBO J 2020
25
Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation.
Mario Hofweber, Saskia Hutten, Benjamin Bourgeois, Emil Spreitzer, Annika Niedner-Boblenz, Martina Schifferer, Marc-David Ruepp, Mikael Simons, Dierk Niessing, Tobias Madl,[...]. Cell 2018
Mario Hofweber, Saskia Hutten, Benjamin Bourgeois, Emil Spreitzer, Annika Niedner-Boblenz, Martina Schifferer, Marc-David Ruepp, Mikael Simons, Dierk Niessing, Tobias Madl,[...]. Cell 2018
25
Engineering and Evolution of Molecular Chaperones and Protein Disaggregases with Enhanced Activity.
Korrie L Mack, James Shorter. Front Mol Biosci 2016
Korrie L Mack, James Shorter. Front Mol Biosci 2016
25
Prion-like disorders: blurring the divide between transmissibility and infectivity.
Mimi Cushman, Brian S Johnson, Oliver D King, Aaron D Gitler, James Shorter. J Cell Sci 2010
Mimi Cushman, Brian S Johnson, Oliver D King, Aaron D Gitler, James Shorter. J Cell Sci 2010
25
Engineering enhanced protein disaggregases for neurodegenerative disease.
Meredith E Jackrel, James Shorter. Prion 2015
Meredith E Jackrel, James Shorter. Prion 2015
25
Expression of a putative ATPase suppresses the growth defect of a yeast potassium transport mutant: identification of a mammalian member of the Clp/HSP104 family.
F Périer, C M Radeke, K F Raab-Graham, C A Vandenberg. Gene 1995
F Périer, C M Radeke, K F Raab-Graham, C A Vandenberg. Gene 1995
25
Stress granules as crucibles of ALS pathogenesis.
Yun R Li, Oliver D King, James Shorter, Aaron D Gitler. J Cell Biol 2013
Yun R Li, Oliver D King, James Shorter, Aaron D Gitler. J Cell Biol 2013
25
Protein homeostasis and the phenotypic manifestation of genetic diversity: principles and mechanisms.
Daniel F Jarosz, Mikko Taipale, Susan Lindquist. Annu Rev Genet 2010
Daniel F Jarosz, Mikko Taipale, Susan Lindquist. Annu Rev Genet 2010
25
Does protein aggregation drive postmitotic tissue degeneration?
Jeffery W Kelly. Sci Transl Med 2021
Jeffery W Kelly. Sci Transl Med 2021
25
Glia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in Mice.
Haibo Zhou, Jinlin Su, Xinde Hu, Changyang Zhou, He Li, Zhaorong Chen, Qingquan Xiao, Bo Wang, Wenyan Wu, Yidi Sun,[...]. Cell 2020
Haibo Zhou, Jinlin Su, Xinde Hu, Changyang Zhou, He Li, Zhaorong Chen, Qingquan Xiao, Bo Wang, Wenyan Wu, Yidi Sun,[...]. Cell 2020
25
Hsp104 suppresses polyglutamine-induced degeneration post onset in a drosophila MJD/SCA3 model.
Mimi Cushman-Nick, Nancy M Bonini, James Shorter. PLoS Genet 2013
Mimi Cushman-Nick, Nancy M Bonini, James Shorter. PLoS Genet 2013
25
FUS and TDP-43 Phases in Health and Disease.
Bede Portz, Bo Lim Lee, James Shorter. Trends Biochem Sci 2021
Bede Portz, Bo Lim Lee, James Shorter. Trends Biochem Sci 2021
25
Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.
Seung W Ryu, Rose Stewart, D Chase Pectol, Nicolette A Ender, Oshadi Wimalarathne, Ji-Hoon Lee, Carlos P Zanini, Antony Harvey, Jon M Huibregtse, Peter Mueller,[...]. PLoS Biol 2020
Seung W Ryu, Rose Stewart, D Chase Pectol, Nicolette A Ender, Oshadi Wimalarathne, Ji-Hoon Lee, Carlos P Zanini, Antony Harvey, Jon M Huibregtse, Peter Mueller,[...]. PLoS Biol 2020
25
Nucleated conformational conversion and the replication of conformational information by a prion determinant.
T R Serio, A G Cashikar, A S Kowal, G J Sawicki, J J Moslehi, L Serpell, M F Arnsdorf, S L Lindquist. Science 2000
T R Serio, A G Cashikar, A S Kowal, G J Sawicki, J J Moslehi, L Serpell, M F Arnsdorf, S L Lindquist. Science 2000
25
ALS/FTLD-Linked Mutations in FUS Glycine Residues Cause Accelerated Gelation and Reduced Interactions with Wild-Type FUS.
Kevin Rhine, Monika A Makurath, James Liu, Sophie Skanchy, Christian Lopez, Kevin F Catalan, Ye Ma, Charlotte M Fare, James Shorter, Taekjip Ha,[...]. Mol Cell 2020
Kevin Rhine, Monika A Makurath, James Liu, Sophie Skanchy, Christian Lopez, Kevin F Catalan, Ye Ma, Charlotte M Fare, James Shorter, Taekjip Ha,[...]. Mol Cell 2020
25
A scoring system predicting the clinical course of CLPB defect based on the foetal and neonatal presentation of 31 patients.
Ewa Pronicka, Mariola Ropacka-Lesiak, Joanna Trubicka, Magdalena Pajdowska, Markus Linke, Elsebet Ostergaard, Carol Saunders, Sandra Horsch, Clara van Karnebeek, Joy Yaplito-Lee,[...]. J Inherit Metab Dis 2017
Ewa Pronicka, Mariola Ropacka-Lesiak, Joanna Trubicka, Magdalena Pajdowska, Markus Linke, Elsebet Ostergaard, Carol Saunders, Sandra Horsch, Clara van Karnebeek, Joy Yaplito-Lee,[...]. J Inherit Metab Dis 2017
25
The metazoan protein disaggregase and amyloid depolymerase system: Hsp110, Hsp70, Hsp40, and small heat shock proteins.
Mariana P Torrente, James Shorter. Prion 2013
Mariana P Torrente, James Shorter. Prion 2013
25
Amyloid assembly and disassembly.
Edward Chuang, Acacia M Hori, Christina D Hesketh, James Shorter. J Cell Sci 2018
Edward Chuang, Acacia M Hori, Christina D Hesketh, James Shorter. J Cell Sci 2018
25
Hsp104 antagonizes alpha-synuclein aggregation and reduces dopaminergic degeneration in a rat model of Parkinson disease.
Christophe Lo Bianco, James Shorter, Etienne Régulier, Hilal Lashuel, Takeshi Iwatsubo, Susan Lindquist, Patrick Aebischer. J Clin Invest 2008
Christophe Lo Bianco, James Shorter, Etienne Régulier, Hilal Lashuel, Takeshi Iwatsubo, Susan Lindquist, Patrick Aebischer. J Clin Invest 2008
25
Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains.
Lin Guo, Hong Joo Kim, Hejia Wang, John Monaghan, Fernande Freyermuth, Julie C Sung, Kevin O'Donovan, Charlotte M Fare, Zamia Diaz, Nikita Singh,[...]. Cell 2018
Lin Guo, Hong Joo Kim, Hejia Wang, John Monaghan, Fernande Freyermuth, Julie C Sung, Kevin O'Donovan, Charlotte M Fare, Zamia Diaz, Nikita Singh,[...]. Cell 2018
25
Targeting Mitochondrial Structure Sensitizes Acute Myeloid Leukemia to Venetoclax Treatment.
Xufeng Chen, Christina Glytsou, Hua Zhou, Sonali Narang, Denis E Reyna, Andrea Lopez, Theodore Sakellaropoulos, Yixiao Gong, Andreas Kloetgen, Yoon Sing Yap,[...]. Cancer Discov 2019
Xufeng Chen, Christina Glytsou, Hua Zhou, Sonali Narang, Denis E Reyna, Andrea Lopez, Theodore Sakellaropoulos, Yixiao Gong, Andreas Kloetgen, Yoon Sing Yap,[...]. Cancer Discov 2019
25
Protein Phase Separation: A New Phase in Cell Biology.
Steven Boeynaems, Simon Alberti, Nicolas L Fawzi, Tanja Mittag, Magdalini Polymenidou, Frederic Rousseau, Joost Schymkowitz, James Shorter, Benjamin Wolozin, Ludo Van Den Bosch,[...]. Trends Cell Biol 2018
Steven Boeynaems, Simon Alberti, Nicolas L Fawzi, Tanja Mittag, Magdalini Polymenidou, Frederic Rousseau, Joost Schymkowitz, James Shorter, Benjamin Wolozin, Ludo Van Den Bosch,[...]. Trends Cell Biol 2018
25
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