Weedon Mn, Jackson L, Harrison Jw, Ruth Ks, Tyrrell J, Hattersley At, Wright Cf. BMJ 2021
Times Cited: 9
Times Cited: 9
Times Cited
Times Co-cited
Similarity
Assessing the Pathogenicity, Penetrance, and Expressivity of Putative Disease-Causing Variants in a Population Setting.
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The UK Biobank resource with deep phenotyping and genomic data.
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Gregory McInnes, Rachel Dalton, Katrin Sangkuhl, Michelle Whirl-Carrillo, Seung-Been Lee, Philip S Tsao, Andrea Gaedigk, Russ B Altman, Erica L Woodahl. PLoS Comput Biol 2020
Gregory McInnes, Rachel Dalton, Katrin Sangkuhl, Michelle Whirl-Carrillo, Seung-Been Lee, Philip S Tsao, Andrea Gaedigk, Russ B Altman, Erica L Woodahl. PLoS Comput Biol 2020
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Drug Response Pharmacogenetics for 200,000 UK Biobank Participants.
Gregory McInnes, Russ B Altman. Pac Symp Biocomput 2021
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A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose.
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Massively parallel characterization of CYP2C9 variant enzyme activity and abundance.
Clara J Amorosi, Melissa A Chiasson, Matthew G McDonald, Lai Hong Wong, Katherine A Sitko, Gabriel Boyle, John P Kowalski, Allan E Rettie, Douglas M Fowler, Maitreya J Dunham. Am J Hum Genet 2021
Clara J Amorosi, Melissa A Chiasson, Matthew G McDonald, Lai Hong Wong, Katherine A Sitko, Gabriel Boyle, John P Kowalski, Allan E Rettie, Douglas M Fowler, Maitreya J Dunham. Am J Hum Genet 2021
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Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study.
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Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin.
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Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program.
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Translating pharmacogenomics into clinical decisions: do not let the perfect be the enemy of the good.
Kristi Krebs, Lili Milani. Hum Genomics 2019
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Pharmacogenetics at Scale: An Analysis of the UK Biobank.
Gregory McInnes, Adam Lavertu, Katrin Sangkuhl, Teri E Klein, Michelle Whirl-Carrillo, Russ B Altman. Clin Pharmacol Ther 2021
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Genome-wide association studies of drug response and toxicity: an opportunity for genome medicine.
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UK biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age.
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Emerging strategies to bridge the gap between pharmacogenomic research and its clinical implementation.
Volker M Lauschke, Magnus Ingelman-Sundberg. NPJ Genom Med 2020
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A global reference for human genetic variation.
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A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose.
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A scientometric review of genome-wide association studies.
Melinda C Mills, Charles Rahal. Commun Biol 2019
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Pharmacogenomics knowledge for personalized medicine.
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Exome sequencing and characterization of 49,960 individuals in the UK Biobank.
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The mutational constraint spectrum quantified from variation in 141,456 humans.
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Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study.
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Very low-depth whole-genome sequencing in complex trait association studies.
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Exome Sequencing-Based Screening for BRCA1/2 Expected Pathogenic Variants Among Adult Biobank Participants.
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Analysis of protein-coding genetic variation in 60,706 humans.
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Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations.
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Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity.
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Unreliability of genotyping arrays for detecting very rare variants in human genetic studies: Example from a recent study of MC4R.
Michael N Weedon, Caroline F Wright, Kashyap A Patel, Timothy M Frayling. Cell 2021
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Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
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11
Prevalence of melanocortin-4 receptor deficiency in Europeans and their age-dependent penetrance in multigenerational pedigrees.
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Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients.
Richard B Kennedy, Inna G Ovsyannikova, V Shane Pankratz, Iana H Haralambieva, Robert A Vierkant, Gregory A Poland. Hum Genet 2012
Richard B Kennedy, Inna G Ovsyannikova, V Shane Pankratz, Iana H Haralambieva, Robert A Vierkant, Gregory A Poland. Hum Genet 2012
11
Genetics of 35 blood and urine biomarkers in the UK Biobank.
Nasa Sinnott-Armstrong, Yosuke Tanigawa, David Amar, Nina Mars, Christian Benner, Matthew Aguirre, Guhan Ram Venkataraman, Michael Wainberg, Hanna M Ollila, Tuomo Kiiskinen,[...]. Nat Genet 2021
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11
Single-nucleotide polymorphisms in HLA- and non-HLA genes associated with the development of antibodies to interferon-β therapy in multiple sclerosis patients.
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Genetic variant in folate homeostasis is associated with lower warfarin dose in African Americans.
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From GWAS to Function: Using Functional Genomics to Identify the Mechanisms Underlying Complex Diseases.
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Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Pharmacogenetics-Guided Warfarin Dosing: 2017 Update.
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Warfarin pharmacogenetics: an illustration of the importance of studies in minority populations.
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Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.
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Emerging strategies to bridge the gap between pharmacogenomic research and its clinical implementation.
Volker M Lauschke, Magnus Ingelman-Sundberg. NPJ Genom Med 2020
Volker M Lauschke, Magnus Ingelman-Sundberg. NPJ Genom Med 2020
14
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.