Xiujin Shen, Haibing Wang, Chunhua Weng, Hong Jiang, Jianghua Chen. Cell Death Dis 2021
Times Cited: 23
Times Cited: 23
Times Cited
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Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin.
Yupeng Wang, Wenqing Gao, Xuyan Shi, Jingjin Ding, Wang Liu, Huabin He, Kun Wang, Feng Shao. Nature 2017
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Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
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Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores.
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Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death.
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Pore-forming activity and structural autoinhibition of the gasdermin family.
Jingjin Ding, Kun Wang, Wang Liu, Yang She, Qi Sun, Jianjin Shi, Hanzi Sun, Da-Cheng Wang, Feng Shao. Nature 2016
Jingjin Ding, Kun Wang, Wang Liu, Yang She, Qi Sun, Jianjin Shi, Hanzi Sun, Da-Cheng Wang, Feng Shao. Nature 2016
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Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation.
Corey Rogers, Dan A Erkes, Alexandria Nardone, Andrew E Aplin, Teresa Fernandes-Alnemri, Emad S Alnemri. Nat Commun 2019
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Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis.
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Aberrant promoter methylation and tumor suppressive activity of the DFNA5 gene in colorectal carcinoma.
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Chemotherapy-induced pyroptosis is mediated by BAK/BAX-caspase-3-GSDME pathway and inhibited by 2-bromopalmitate.
Lei Hu, Meng Chen, Xueran Chen, Chenggang Zhao, Zhiyou Fang, Hongzhi Wang, Haiming Dai. Cell Death Dis 2020
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Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells.
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Molecular Targeted Therapies Elicit Concurrent Apoptotic and GSDME-Dependent Pyroptotic Tumor Cell Death.
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Gasdermin E suppresses tumour growth by activating anti-tumour immunity.
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Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.
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Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion.
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PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis.
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Cleavage of GSDME by caspase-3 determines lobaplatin-induced pyroptosis in colon cancer cells.
Junhui Yu, Shan Li, Jie Qi, Zilu Chen, Yunhua Wu, Jing Guo, Kai Wang, Xuejun Sun, Jianbao Zheng. Cell Death Dis 2019
Junhui Yu, Shan Li, Jie Qi, Zilu Chen, Yunhua Wu, Jing Guo, Kai Wang, Xuejun Sun, Jianbao Zheng. Cell Death Dis 2019
30
Gasdermin E deficiency attenuates acute kidney injury by inhibiting pyroptosis and inflammation.
Weiwei Xia, Yuanyuan Li, Mengying Wu, Qianqian Jin, Qian Wang, Shuzhen Li, Songming Huang, Aihua Zhang, Yue Zhang, Zhanjun Jia. Cell Death Dis 2021
Weiwei Xia, Yuanyuan Li, Mengying Wu, Qianqian Jin, Qian Wang, Shuzhen Li, Songming Huang, Aihua Zhang, Yue Zhang, Zhanjun Jia. Cell Death Dis 2021
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Succination inactivates gasdermin D and blocks pyroptosis.
Fiachra Humphries, Liraz Shmuel-Galia, Natalia Ketelut-Carneiro, Sheng Li, Bingwei Wang, Venkatesh V Nemmara, Ruth Wilson, Zhaozhao Jiang, Farnaz Khalighinejad, Khaja Muneeruddin,[...]. Science 2020
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30
Tetraarsenic hexoxide enhances generation of mitochondrial ROS to promote pyroptosis by inducing the activation of caspase-3/GSDME in triple-negative breast cancer cells.
Haein An, Jin Sun Heo, Pyunggang Kim, Zenglin Lian, Siyoung Lee, Jinah Park, Eunji Hong, Kyoungwha Pang, Yuna Park, Akira Ooshima,[...]. Cell Death Dis 2021
Haein An, Jin Sun Heo, Pyunggang Kim, Zenglin Lian, Siyoung Lee, Jinah Park, Eunji Hong, Kyoungwha Pang, Yuna Park, Akira Ooshima,[...]. Cell Death Dis 2021
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Gasdermin (Gsdm) localizing to mouse Chromosome 11 is predominantly expressed in upper gastrointestinal tract but significantly suppressed in human gastric cancer cells.
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Chemotherapeutic paclitaxel and cisplatin differentially induce pyroptosis in A549 lung cancer cells via caspase-3/GSDME activation.
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Cheng-Cheng Zhang, Chen-Guang Li, Yao-Feng Wang, Li-Hui Xu, Xian-Hui He, Qiong-Zhen Zeng, Chen-Ying Zeng, Feng-Yi Mai, Bo Hu, Dong-Yun Ouyang. Apoptosis 2019
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A bioorthogonal system reveals antitumour immune function of pyroptosis.
Qinyang Wang, Yupeng Wang, Jingjin Ding, Chunhong Wang, Xuehan Zhou, Wenqing Gao, Huanwei Huang, Feng Shao, Zhibo Liu. Nature 2020
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Mutant BRAF and MEK Inhibitors Regulate the Tumor Immune Microenvironment via Pyroptosis.
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Nonsyndromic hearing impairment is associated with a mutation in DFNA5.
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17
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.