Ya-Shuo Feng, Zi-Xuan Tan, Lin-Yu Wu, Fang Dong, Feng Zhang. Biomed Pharmacother 2021
Times Cited: 13
Times Cited: 13
Times Cited
Times Co-cited
Similarity
NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.
Michael T Heneka, Markus P Kummer, Andrea Stutz, Andrea Delekate, Stephanie Schwartz, Ana Vieira-Saecker, Angelika Griep, Daisy Axt, Anita Remus, Te-Chen Tzeng,[...]. Nature 2013
Michael T Heneka, Markus P Kummer, Andrea Stutz, Andrea Delekate, Stephanie Schwartz, Ana Vieira-Saecker, Angelika Griep, Daisy Axt, Anita Remus, Te-Chen Tzeng,[...]. Nature 2013
38
Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models.
Michael J D Daniels, Jack Rivers-Auty, Tom Schilling, Nicholas G Spencer, William Watremez, Victoria Fasolino, Sophie J Booth, Claire S White, Alex G Baldwin, Sally Freeman,[...]. Nat Commun 2016
Michael J D Daniels, Jack Rivers-Auty, Tom Schilling, Nicholas G Spencer, William Watremez, Victoria Fasolino, Sophie J Booth, Claire S White, Alex G Baldwin, Sally Freeman,[...]. Nat Commun 2016
30
NLRP3 inflammasome activation drives tau pathology.
Christina Ising, Carmen Venegas, Shuangshuang Zhang, Hannah Scheiblich, Susanne V Schmidt, Ana Vieira-Saecker, Stephanie Schwartz, Shadi Albasset, Róisín M McManus, Dario Tejera,[...]. Nature 2019
Christina Ising, Carmen Venegas, Shuangshuang Zhang, Hannah Scheiblich, Susanne V Schmidt, Ana Vieira-Saecker, Stephanie Schwartz, Shadi Albasset, Róisín M McManus, Dario Tejera,[...]. Nature 2019
30
Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer's disease.
Carmen Venegas, Sathish Kumar, Bernardo S Franklin, Tobias Dierkes, Rebecca Brinkschulte, Dario Tejera, Ana Vieira-Saecker, Stephanie Schwartz, Francesco Santarelli, Markus P Kummer,[...]. Nature 2017
Carmen Venegas, Sathish Kumar, Bernardo S Franklin, Tobias Dierkes, Rebecca Brinkschulte, Dario Tejera, Ana Vieira-Saecker, Stephanie Schwartz, Francesco Santarelli, Markus P Kummer,[...]. Nature 2017
30
Inhibiting the NLRP3 inflammasome with MCC950 promotes non-phlogistic clearance of amyloid-β and cognitive function in APP/PS1 mice.
C Dempsey, A Rubio Araiz, K J Bryson, O Finucane, C Larkin, E L Mills, A A B Robertson, M A Cooper, L A J O'Neill, M A Lynch. Brain Behav Immun 2017
C Dempsey, A Rubio Araiz, K J Bryson, O Finucane, C Larkin, E L Mills, A A B Robertson, M A Cooper, L A J O'Neill, M A Lynch. Brain Behav Immun 2017
30
The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer's disease.
Marina Saresella, Francesca La Rosa, Federica Piancone, Martina Zoppis, Ivana Marventano, Elena Calabrese, Veronica Rainone, Raffaello Nemni, Roberta Mancuso, Mario Clerici. Mol Neurodegener 2016
Marina Saresella, Francesca La Rosa, Federica Piancone, Martina Zoppis, Ivana Marventano, Elena Calabrese, Veronica Rainone, Raffaello Nemni, Roberta Mancuso, Mario Clerici. Mol Neurodegener 2016
30
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Jianjin Shi, Yue Zhao, Kun Wang, Xuyan Shi, Yue Wang, Huanwei Huang, Yinghua Zhuang, Tao Cai, Fengchao Wang, Feng Shao. Nature 2015
Jianjin Shi, Yue Zhao, Kun Wang, Xuyan Shi, Yue Wang, Huanwei Huang, Yinghua Zhuang, Tao Cai, Fengchao Wang, Feng Shao. Nature 2015
30
Protection of MCC950 against Alzheimer's disease via inhibiting neuronal pyroptosis in SAMP8 mice.
Jie Li, Lili Zhuang, Xiaoqing Luo, Jianheng Liang, Erwei Sun, Yi He. Exp Brain Res 2020
Jie Li, Lili Zhuang, Xiaoqing Luo, Jianheng Liang, Erwei Sun, Yi He. Exp Brain Res 2020
25
The amyloid hypothesis of Alzheimer's disease at 25 years.
Dennis J Selkoe, John Hardy. EMBO Mol Med 2016
Dennis J Selkoe, John Hardy. EMBO Mol Med 2016
23
New mechanism of nerve injury in Alzheimer's disease: β-amyloid-induced neuronal pyroptosis.
Chenyang Han, Yi Yang, Qiaobing Guan, Xiaoling Zhang, Heping Shen, Yongjia Sheng, Jin Wang, Xiaohong Zhou, Wenyan Li, Li Guo,[...]. J Cell Mol Med 2020
Chenyang Han, Yi Yang, Qiaobing Guan, Xiaoling Zhang, Heping Shen, Yongjia Sheng, Jin Wang, Xiaohong Zhou, Wenyan Li, Li Guo,[...]. J Cell Mol Med 2020
23
The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation.
Nathan Kelley, Devon Jeltema, Yanhui Duan, Yuan He. Int J Mol Sci 2019
Nathan Kelley, Devon Jeltema, Yanhui Duan, Yuan He. Int J Mol Sci 2019
23
The NALP3 inflammasome is involved in the innate immune response to amyloid-beta.
Annett Halle, Veit Hornung, Gabor C Petzold, Cameron R Stewart, Brian G Monks, Thomas Reinheckel, Katherine A Fitzgerald, Eicke Latz, Kathryn J Moore, Douglas T Golenbock. Nat Immunol 2008
Annett Halle, Veit Hornung, Gabor C Petzold, Cameron R Stewart, Brian G Monks, Thomas Reinheckel, Katherine A Fitzgerald, Eicke Latz, Kathryn J Moore, Douglas T Golenbock. Nat Immunol 2008
23
The Role of the Inflammasome in Neurodegenerative Diseases.
Federica Piancone, Francesca La Rosa, Ivana Marventano, Marina Saresella, Mario Clerici. Molecules 2021
Federica Piancone, Francesca La Rosa, Ivana Marventano, Marina Saresella, Mario Clerici. Molecules 2021
23
Mechanisms of NLRP3 Inflammasome Activation: Its Role in the Treatment of Alzheimer's Disease.
Yidan Zhang, Yuan Zhao, Jian Zhang, Guofeng Yang. Neurochem Res 2020
Yidan Zhang, Yuan Zhao, Jian Zhang, Guofeng Yang. Neurochem Res 2020
15
Glyburide inhibits the Cryopyrin/Nalp3 inflammasome.
Mohamed Lamkanfi, James L Mueller, Alberto C Vitari, Shahram Misaghi, Anna Fedorova, Kurt Deshayes, Wyne P Lee, Hal M Hoffman, Vishva M Dixit. J Cell Biol 2009
Mohamed Lamkanfi, James L Mueller, Alberto C Vitari, Shahram Misaghi, Anna Fedorova, Kurt Deshayes, Wyne P Lee, Hal M Hoffman, Vishva M Dixit. J Cell Biol 2009
15
The NLRP3 inflammasome inhibitor OLT1177 rescues cognitive impairment in a mouse model of Alzheimer's disease.
Niklas Lonnemann, Shirin Hosseini, Carlo Marchetti, Damaris B Skouras, Davide Stefanoni, Angelo D'Alessandro, Charles A Dinarello, Martin Korte. Proc Natl Acad Sci U S A 2020
Niklas Lonnemann, Shirin Hosseini, Carlo Marchetti, Damaris B Skouras, Davide Stefanoni, Angelo D'Alessandro, Charles A Dinarello, Martin Korte. Proc Natl Acad Sci U S A 2020
15
NLRP3 expression in mesencephalic neurons and characterization of a rare NLRP3 polymorphism associated with decreased risk of Parkinson's disease.
Katharine M von Herrmann, Lucas A Salas, Eileen M Martinez, Alison L Young, Joseph M Howard, Mary S Feldman, Brock C Christensen, Owen M Wilkins, Stephen L Lee, William F Hickey,[...]. NPJ Parkinsons Dis 2018
Katharine M von Herrmann, Lucas A Salas, Eileen M Martinez, Alison L Young, Joseph M Howard, Mary S Feldman, Brock C Christensen, Owen M Wilkins, Stephen L Lee, William F Hickey,[...]. NPJ Parkinsons Dis 2018
15
β-Hydroxybutyrate inhibits inflammasome activation to attenuate Alzheimer's disease pathology.
Daniel C Shippy, Connor Wilhelm, Patel A Viharkumar, Thomas J Raife, Tyler K Ulland. J Neuroinflammation 2020
Daniel C Shippy, Connor Wilhelm, Patel A Viharkumar, Thomas J Raife, Tyler K Ulland. J Neuroinflammation 2020
15
NLRP3 Inflammasome in Neurological Diseases, from Functions to Therapies.
Limin Song, Lei Pei, Shanglong Yao, Yan Wu, You Shang. Front Cell Neurosci 2017
Limin Song, Lei Pei, Shanglong Yao, Yan Wu, You Shang. Front Cell Neurosci 2017
15
OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation.
Carlo Marchetti, Benjamin Swartzwelter, Fabia Gamboni, Charles P Neff, Katrin Richter, Tania Azam, Sonia Carta, Isak Tengesdal, Travis Nemkov, Angelo D'Alessandro,[...]. Proc Natl Acad Sci U S A 2018
Carlo Marchetti, Benjamin Swartzwelter, Fabia Gamboni, Charles P Neff, Katrin Richter, Tania Azam, Sonia Carta, Isak Tengesdal, Travis Nemkov, Angelo D'Alessandro,[...]. Proc Natl Acad Sci U S A 2018
15
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.
Rebecca C Coll, Avril A B Robertson, Jae Jin Chae, Sarah C Higgins, Raúl Muñoz-Planillo, Marco C Inserra, Irina Vetter, Lara S Dungan, Brian G Monks, Andrea Stutz,[...]. Nat Med 2015
Rebecca C Coll, Avril A B Robertson, Jae Jin Chae, Sarah C Higgins, Raúl Muñoz-Planillo, Marco C Inserra, Irina Vetter, Lara S Dungan, Brian G Monks, Andrea Stutz,[...]. Nat Med 2015
15
Interleukin-1 mediates Alzheimer and Lewy body pathologies.
W Sue T Griffin, Ling Liu, Yuekui Li, Robert E Mrak, Steven W Barger. J Neuroinflammation 2006
W Sue T Griffin, Ling Liu, Yuekui Li, Robert E Mrak, Steven W Barger. J Neuroinflammation 2006
15
NLRP3 Inflammasome Inhibitor Ameliorates Amyloid Pathology in a Mouse Model of Alzheimer's Disease.
Jun Yin, Fanpeng Zhao, Jeremy E Chojnacki, Jacob Fulp, William L Klein, Shijun Zhang, Xiongwei Zhu. Mol Neurobiol 2018
Jun Yin, Fanpeng Zhao, Jeremy E Chojnacki, Jacob Fulp, William L Klein, Shijun Zhang, Xiongwei Zhu. Mol Neurobiol 2018
15
Expression of interleukin-18 is increased in the brains of Alzheimer's disease patients.
Johanna Ojala, Irina Alafuzoff, Sanna-Kaisa Herukka, Thomas van Groen, Heikki Tanila, Tuula Pirttilä. Neurobiol Aging 2009
Johanna Ojala, Irina Alafuzoff, Sanna-Kaisa Herukka, Thomas van Groen, Heikki Tanila, Tuula Pirttilä. Neurobiol Aging 2009
15
Human astrocytes express a novel NLRP2 inflammasome.
Julia Minkiewicz, Juan Pablo de Rivero Vaccari, Robert W Keane. Glia 2013
Julia Minkiewicz, Juan Pablo de Rivero Vaccari, Robert W Keane. Glia 2013
15
NLRP3-dependent synaptic plasticity deficit in an Alzheimer's disease amyloidosis model in vivo.
Yingjie Qi, Igor Klyubin, A Claudio Cuello, Michael J Rowan. Neurobiol Dis 2018
Yingjie Qi, Igor Klyubin, A Claudio Cuello, Michael J Rowan. Neurobiol Dis 2018
15
Caspase-1 inhibition prevents glial inflammasome activation and pyroptosis in models of multiple sclerosis.
Brienne A McKenzie, Manmeet K Mamik, Leina B Saito, Roobina Boghozian, Maria Chiara Monaco, Eugene O Major, Jian-Qiang Lu, William G Branton, Christopher Power. Proc Natl Acad Sci U S A 2018
Brienne A McKenzie, Manmeet K Mamik, Leina B Saito, Roobina Boghozian, Maria Chiara Monaco, Eugene O Major, Jian-Qiang Lu, William G Branton, Christopher Power. Proc Natl Acad Sci U S A 2018
15
Inflammasome activation and regulation: toward a better understanding of complex mechanisms.
Danping Zheng, Timur Liwinski, Eran Elinav. Cell Discov 2020
Danping Zheng, Timur Liwinski, Eran Elinav. Cell Discov 2020
15
A novel small molecular NLRP3 inflammasome inhibitor alleviates neuroinflammatory response following traumatic brain injury.
Ram Kuwar, Andrew Rolfe, Long Di, Hongyu Xu, Liu He, Yuqi Jiang, Shijun Zhang, Dong Sun. J Neuroinflammation 2019
Ram Kuwar, Andrew Rolfe, Long Di, Hongyu Xu, Liu He, Yuqi Jiang, Shijun Zhang, Dong Sun. J Neuroinflammation 2019
15
Inflammasomes: mechanism of assembly, regulation and signalling.
Petr Broz, Vishva M Dixit. Nat Rev Immunol 2016
Petr Broz, Vishva M Dixit. Nat Rev Immunol 2016
15
The Role of Microglia and the Nlrp3 Inflammasome in Alzheimer's Disease.
Kendra L Hanslik, Tyler K Ulland. Front Neurol 2020
Kendra L Hanslik, Tyler K Ulland. Front Neurol 2020
15
Dopamine D1 receptor agonist A-68930 ameliorates Aβ1-42-induced cognitive impairment and neuroinflammation in mice.
Zhao-Yan Cheng, Qing-Peng Xia, Yu-Hui Hu, Chen Wang, Ling He. Int Immunopharmacol 2020
Zhao-Yan Cheng, Qing-Peng Xia, Yu-Hui Hu, Chen Wang, Ling He. Int Immunopharmacol 2020
25
Aggregated Tau activates NLRP3-ASC inflammasome exacerbating exogenously seeded and non-exogenously seeded Tau pathology in vivo.
Ilie-Cosmin Stancu, Niels Cremers, Hannah Vanrusselt, Julien Couturier, Alexandre Vanoosthuyse, Sofie Kessels, Chritica Lodder, Bert Brône, François Huaux, Jean-Noël Octave,[...]. Acta Neuropathol 2019
Ilie-Cosmin Stancu, Niels Cremers, Hannah Vanrusselt, Julien Couturier, Alexandre Vanoosthuyse, Sofie Kessels, Chritica Lodder, Bert Brône, François Huaux, Jean-Noël Octave,[...]. Acta Neuropathol 2019
15
Caspase-1 inhibition alleviates cognitive impairment and neuropathology in an Alzheimer's disease mouse model.
Joseph Flores, Anastasia Noël, Bénédicte Foveau, Jeffrey Lynham, Clotilde Lecrux, Andréa C LeBlanc. Nat Commun 2018
Joseph Flores, Anastasia Noël, Bénédicte Foveau, Jeffrey Lynham, Clotilde Lecrux, Andréa C LeBlanc. Nat Commun 2018
15
CSB6B prevents β-amyloid-associated neuroinflammation and cognitive impairments via inhibiting NF-κB and NLRP3 in microglia cells.
Sicheng Yan, Zhenquan Xuan, Mengxiang Yang, Chuang Wang, Tao Tao, Qinwen Wang, Wei Cui. Int Immunopharmacol 2020
Sicheng Yan, Zhenquan Xuan, Mengxiang Yang, Chuang Wang, Tao Tao, Qinwen Wang, Wei Cui. Int Immunopharmacol 2020
15
The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta.
Fabio Martinon, Kimberly Burns, Jürg Tschopp. Mol Cell 2002
Fabio Martinon, Kimberly Burns, Jürg Tschopp. Mol Cell 2002
15
New mitochondrial DNA synthesis enables NLRP3 inflammasome activation.
Zhenyu Zhong, Shuang Liang, Elsa Sanchez-Lopez, Feng He, Shabnam Shalapour, Xue-Jia Lin, Jerry Wong, Siyuan Ding, Ekihiro Seki, Bernd Schnabl,[...]. Nature 2018
Zhenyu Zhong, Shuang Liang, Elsa Sanchez-Lopez, Feng He, Shabnam Shalapour, Xue-Jia Lin, Jerry Wong, Siyuan Ding, Ekihiro Seki, Bernd Schnabl,[...]. Nature 2018
15
MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition.
Rebecca C Coll, James R Hill, Christopher J Day, Alina Zamoshnikova, Dave Boucher, Nicholas L Massey, Jessica L Chitty, James A Fraser, Michael P Jennings, Avril A B Robertson,[...]. Nat Chem Biol 2019
Rebecca C Coll, James R Hill, Christopher J Day, Alina Zamoshnikova, Dave Boucher, Nicholas L Massey, Jessica L Chitty, James A Fraser, Michael P Jennings, Avril A B Robertson,[...]. Nat Chem Biol 2019
15
Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity.
Hongbin He, Hua Jiang, Yun Chen, Jin Ye, Aoli Wang, Chao Wang, Qingsong Liu, Gaolin Liang, Xianming Deng, Wei Jiang,[...]. Nat Commun 2018
Hongbin He, Hua Jiang, Yun Chen, Jin Ye, Aoli Wang, Chao Wang, Qingsong Liu, Gaolin Liang, Xianming Deng, Wei Jiang,[...]. Nat Commun 2018
15
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis.
Kenichi Shimada, Timothy R Crother, Justin Karlin, Jargalsaikhan Dagvadorj, Norika Chiba, Shuang Chen, V Krishnan Ramanujan, Andrea J Wolf, Laurent Vergnes, David M Ojcius,[...]. Immunity 2012
Kenichi Shimada, Timothy R Crother, Justin Karlin, Jargalsaikhan Dagvadorj, Norika Chiba, Shuang Chen, V Krishnan Ramanujan, Andrea J Wolf, Laurent Vergnes, David M Ojcius,[...]. Immunity 2012
15
Critical role for calcium mobilization in activation of the NLRP3 inflammasome.
Tomohiko Murakami, Johan Ockinger, Jiujiu Yu, Vanessa Byles, Aisleen McColl, Aldebaran M Hofer, Tiffany Horng. Proc Natl Acad Sci U S A 2012
Tomohiko Murakami, Johan Ockinger, Jiujiu Yu, Vanessa Byles, Aisleen McColl, Aldebaran M Hofer, Tiffany Horng. Proc Natl Acad Sci U S A 2012
15
The NLRP3 inflammasome: molecular activation and regulation to therapeutics.
Karen V Swanson, Meng Deng, Jenny P-Y Ting. Nat Rev Immunol 2019
Karen V Swanson, Meng Deng, Jenny P-Y Ting. Nat Rev Immunol 2019
15
Calcium signaling and mitochondrial destabilization in the triggering of the NLRP3 inflammasome.
Tiffany Horng. Trends Immunol 2014
Tiffany Horng. Trends Immunol 2014
15
Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.
Franz G Bauernfeind, Gabor Horvath, Andrea Stutz, Emad S Alnemri, Kelly MacDonald, David Speert, Teresa Fernandes-Alnemri, Jianghong Wu, Brian G Monks, Katherine A Fitzgerald,[...]. J Immunol 2009
Franz G Bauernfeind, Gabor Horvath, Andrea Stutz, Emad S Alnemri, Kelly MacDonald, David Speert, Teresa Fernandes-Alnemri, Jianghong Wu, Brian G Monks, Katherine A Fitzgerald,[...]. J Immunol 2009
15
NLRP3 phosphorylation in its LRR domain critically regulates inflammasome assembly.
Tingting Niu, Charlotte De Rosny, Séverine Chautard, Amaury Rey, Danish Patoli, Marine Groslambert, Camille Cosson, Brice Lagrange, Zhirong Zhang, Orane Visvikis,[...]. Nat Commun 2021
Tingting Niu, Charlotte De Rosny, Séverine Chautard, Amaury Rey, Danish Patoli, Marine Groslambert, Camille Cosson, Brice Lagrange, Zhirong Zhang, Orane Visvikis,[...]. Nat Commun 2021
20
Mitochondrial cardiolipin is required for Nlrp3 inflammasome activation.
Shankar S Iyer, Qiong He, John R Janczy, Eric I Elliott, Zhenyu Zhong, Alicia K Olivier, Jeffrey J Sadler, Vickie Knepper-Adrian, Renzhi Han, Liang Qiao,[...]. Immunity 2013
Shankar S Iyer, Qiong He, John R Janczy, Eric I Elliott, Zhenyu Zhong, Alicia K Olivier, Jeffrey J Sadler, Vickie Knepper-Adrian, Renzhi Han, Liang Qiao,[...]. Immunity 2013
15
Picrorhiza kurroa Prevents Memory Deficits by Inhibiting NLRP3 Inflammasome Activation and BACE1 Expression in 5xFAD Mice.
Namkwon Kim, Jimin Do, In Gyoung Ju, Seung Ho Jeon, Jong Kil Lee, Myung Sook Oh. Neurotherapeutics 2020
Namkwon Kim, Jimin Do, In Gyoung Ju, Seung Ho Jeon, Jong Kil Lee, Myung Sook Oh. Neurotherapeutics 2020
15
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.
Yun-Hee Youm, Kim Y Nguyen, Ryan W Grant, Emily L Goldberg, Monica Bodogai, Dongin Kim, Dominic D'Agostino, Noah Planavsky, Christopher Lupfer, Thirumala D Kanneganti,[...]. Nat Med 2015
Yun-Hee Youm, Kim Y Nguyen, Ryan W Grant, Emily L Goldberg, Monica Bodogai, Dongin Kim, Dominic D'Agostino, Noah Planavsky, Christopher Lupfer, Thirumala D Kanneganti,[...]. Nat Med 2015
15
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.