Eva Parobkova, Radoslav Matej. Diagnostics (Basel) 2021
Times Cited: 2
Times Cited: 2
Times Cited
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Is SOD1 loss of function involved in amyotrophic lateral sclerosis?
Rachele A Saccon, Rosie K A Bunton-Stasyshyn, Elizabeth M C Fisher, Pietro Fratta. Brain 2013
Rachele A Saccon, Rosie K A Bunton-Stasyshyn, Elizabeth M C Fisher, Pietro Fratta. Brain 2013
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p62 accumulates and enhances aggregate formation in model systems of familial amyotrophic lateral sclerosis.
Jozsef Gal, Anna-Lena Ström, Renee Kilty, Fujian Zhang, Haining Zhu. J Biol Chem 2007
Jozsef Gal, Anna-Lena Ström, Renee Kilty, Fujian Zhang, Haining Zhu. J Biol Chem 2007
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p62 links the autophagy pathway and the ubiqutin-proteasome system upon ubiquitinated protein degradation.
Wei Jing Liu, Lin Ye, Wei Fang Huang, Lin Jie Guo, Zi Gan Xu, Hong Luan Wu, Chen Yang, Hua Feng Liu. Cell Mol Biol Lett 2016
Wei Jing Liu, Lin Ye, Wei Fang Huang, Lin Jie Guo, Zi Gan Xu, Hong Luan Wu, Chen Yang, Hua Feng Liu. Cell Mol Biol Lett 2016
100
Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss.
Jelena Scekic-Zahirovic, Oliver Sendscheid, Hajer El Oussini, Mélanie Jambeau, Ying Sun, Sina Mersmann, Marina Wagner, Stéphane Dieterlé, Jérome Sinniger, Sylvie Dirrig-Grosch,[...]. EMBO J 2016
Jelena Scekic-Zahirovic, Oliver Sendscheid, Hajer El Oussini, Mélanie Jambeau, Ying Sun, Sina Mersmann, Marina Wagner, Stéphane Dieterlé, Jérome Sinniger, Sylvie Dirrig-Grosch,[...]. EMBO J 2016
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p62 overexpression induces TDP-43 cytoplasmic mislocalisation, aggregation and cleavage and neuronal death.
A D Foster, L L Flynn, C Cluning, F Cheng, J M Davidson, A Lee, N Polain, R Mejzini, N Farrawell, J J Yerbury,[...]. Sci Rep 2021
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Gain-of-function profilin 1 mutations linked to familial amyotrophic lateral sclerosis cause seed-dependent intracellular TDP-43 aggregation.
Yoshinori Tanaka, Takashi Nonaka, Genjiro Suzuki, Fuyuki Kametani, Masato Hasegawa. Hum Mol Genet 2016
Yoshinori Tanaka, Takashi Nonaka, Genjiro Suzuki, Fuyuki Kametani, Masato Hasegawa. Hum Mol Genet 2016
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Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons.
Yingxiao Shi, Shaoyu Lin, Kim A Staats, Yichen Li, Wen-Hsuan Chang, Shu-Ting Hung, Eric Hendricks, Gabriel R Linares, Yaoming Wang, Esther Y Son,[...]. Nat Med 2018
Yingxiao Shi, Shaoyu Lin, Kim A Staats, Yichen Li, Wen-Hsuan Chang, Shu-Ting Hung, Eric Hendricks, Gabriel R Linares, Yaoming Wang, Esther Y Son,[...]. Nat Med 2018
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Structural analysis of disease-related TDP-43 D169G mutation: linking enhanced stability and caspase cleavage efficiency to protein accumulation.
Chien-Hao Chiang, Cédric Grauffel, Lien-Szu Wu, Pan-Hsien Kuo, Lyudmila G Doudeva, Carmay Lim, Che-Kun James Shen, Hanna S Yuan. Sci Rep 2016
Chien-Hao Chiang, Cédric Grauffel, Lien-Szu Wu, Pan-Hsien Kuo, Lyudmila G Doudeva, Carmay Lim, Che-Kun James Shen, Hanna S Yuan. Sci Rep 2016
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Molecular perspectives on p97-VCP: progress in understanding its structure and diverse biological functions.
Qing Wang, Changcheng Song, Chou-Chi H Li. J Struct Biol 2004
Qing Wang, Changcheng Song, Chou-Chi H Li. J Struct Biol 2004
50
Melatonin inhibits the caspase-1/cytochrome c/caspase-3 cell death pathway, inhibits MT1 receptor loss and delays disease progression in a mouse model of amyotrophic lateral sclerosis.
Yi Zhang, Anna Cook, Jinho Kim, Sergei V Baranov, Jiying Jiang, Karen Smith, Kerry Cormier, Erik Bennett, Robert P Browser, Arthur L Day,[...]. Neurobiol Dis 2013
Yi Zhang, Anna Cook, Jinho Kim, Sergei V Baranov, Jiying Jiang, Karen Smith, Kerry Cormier, Erik Bennett, Robert P Browser, Arthur L Day,[...]. Neurobiol Dis 2013
50
Modulation of intracellular calcium homeostasis blocks autophagosome formation.
Nikolai Engedal, Maria L Torgersen, Ingrid J Guldvik, Stefan J Barfeld, Daniela Bakula, Frank Sætre, Linda K Hagen, John B Patterson, Tassula Proikas-Cezanne, Per O Seglen,[...]. Autophagy 2013
Nikolai Engedal, Maria L Torgersen, Ingrid J Guldvik, Stefan J Barfeld, Daniela Bakula, Frank Sætre, Linda K Hagen, John B Patterson, Tassula Proikas-Cezanne, Per O Seglen,[...]. Autophagy 2013
50
Calpain-1 cleaves and activates caspase-7.
Juliette Gafni, Xin Cong, Sylvia F Chen, Bradford W Gibson, Lisa M Ellerby. J Biol Chem 2009
Juliette Gafni, Xin Cong, Sylvia F Chen, Bradford W Gibson, Lisa M Ellerby. J Biol Chem 2009
50
Role of calpain-1 in the early phase of experimental ALS.
R Stifanese, M Averna, R De Tullio, M Pedrazzi, M Milanese, T Bonifacino, G Bonanno, F Salamino, S Pontremoli, E Melloni. Arch Biochem Biophys 2014
R Stifanese, M Averna, R De Tullio, M Pedrazzi, M Milanese, T Bonifacino, G Bonanno, F Salamino, S Pontremoli, E Melloni. Arch Biochem Biophys 2014
50
Matrin 3-dependent neurotoxicity is modified by nucleic acid binding and nucleocytoplasmic localization.
Ahmed M Malik, Roberto A Miguez, Xingli Li, Ye-Shih Ho, Eva L Feldman, Sami J Barmada. Elife 2018
Ahmed M Malik, Roberto A Miguez, Xingli Li, Ye-Shih Ho, Eva L Feldman, Sami J Barmada. Elife 2018
50
Matrin 3 is a Ca2+/calmodulin-binding protein cleaved by caspases.
C Alexander Valencia, Wujian Ju, Rihe Liu. Biochem Biophys Res Commun 2007
C Alexander Valencia, Wujian Ju, Rihe Liu. Biochem Biophys Res Commun 2007
50
Calcium dysregulation, mitochondrial pathology and protein aggregation in a culture model of amyotrophic lateral sclerosis: mechanistic relationship and differential sensitivity to intervention.
Miranda L Tradewell, Laura A Cooper, Sandra Minotti, Heather D Durham. Neurobiol Dis 2011
Miranda L Tradewell, Laura A Cooper, Sandra Minotti, Heather D Durham. Neurobiol Dis 2011
50
Caspases: a molecular switch node in the crosstalk between autophagy and apoptosis.
Haijian Wu, Xiaoru Che, Qiaoli Zheng, An Wu, Kun Pan, Anwen Shao, Qun Wu, Jianmin Zhang, Yuan Hong. Int J Biol Sci 2014
Haijian Wu, Xiaoru Che, Qiaoli Zheng, An Wu, Kun Pan, Anwen Shao, Qun Wu, Jianmin Zhang, Yuan Hong. Int J Biol Sci 2014
50
Reduced cellular Ca(2+) availability enhances TDP-43 cleavage by apoptotic caspases.
Giovanni De Marco, Annarosa Lomartire, Giorgia Mandili, Elisa Lupino, Barbara Buccinnà, Cristina Ramondetti, Cristina Moglia, Francesco Novelli, Marco Piccinini, Michael Mostert,[...]. Biochim Biophys Acta 2014
Giovanni De Marco, Annarosa Lomartire, Giorgia Mandili, Elisa Lupino, Barbara Buccinnà, Cristina Ramondetti, Cristina Moglia, Francesco Novelli, Marco Piccinini, Michael Mostert,[...]. Biochim Biophys Acta 2014
50
Induction of autophagy mitigates TDP-43 pathology and translational repression of neurofilament mRNAs in mouse models of ALS/FTD.
Sunny Kumar, Daniel Phaneuf, Pierre Cordeau, Hejer Boutej, Jasna Kriz, Jean-Pierre Julien. Mol Neurodegener 2021
Sunny Kumar, Daniel Phaneuf, Pierre Cordeau, Hejer Boutej, Jasna Kriz, Jean-Pierre Julien. Mol Neurodegener 2021
50
Excitotoxicity and amyotrophic lateral sclerosis.
P Van Damme, M Dewil, W Robberecht, L Van Den Bosch. Neurodegener Dis 2005
P Van Damme, M Dewil, W Robberecht, L Van Den Bosch. Neurodegener Dis 2005
50
50
Functions of FUS/TLS from DNA repair to stress response: implications for ALS.
Reddy Ranjith Kumar Sama, Catherine L Ward, Daryl A Bosco. ASN Neuro 2014
Reddy Ranjith Kumar Sama, Catherine L Ward, Daryl A Bosco. ASN Neuro 2014
50
50
The Enigmatic Role of C9ORF72 in Autophagy.
Melissa Nassif, Ute Woehlbier, Patricio A Manque. Front Neurosci 2017
Melissa Nassif, Ute Woehlbier, Patricio A Manque. Front Neurosci 2017
50
Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43.
Yong-Jie Zhang, Ya-fei Xu, Chad A Dickey, Emanuele Buratti, Francisco Baralle, Rachel Bailey, Stuart Pickering-Brown, Dennis Dickson, Leonard Petrucelli. J Neurosci 2007
Yong-Jie Zhang, Ya-fei Xu, Chad A Dickey, Emanuele Buratti, Francisco Baralle, Rachel Bailey, Stuart Pickering-Brown, Dennis Dickson, Leonard Petrucelli. J Neurosci 2007
50
Direct cleavage by the calcium-activated protease calpain can lead to inactivation of caspases.
B T Chua, K Guo, P Li. J Biol Chem 2000
B T Chua, K Guo, P Li. J Biol Chem 2000
50
Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease.
Jeong-Sun Ju, Rodrigo A Fuentealba, Sara E Miller, Erin Jackson, David Piwnica-Worms, Robert H Baloh, Conrad C Weihl. J Cell Biol 2009
Jeong-Sun Ju, Rodrigo A Fuentealba, Sara E Miller, Erin Jackson, David Piwnica-Worms, Robert H Baloh, Conrad C Weihl. J Cell Biol 2009
50
Role of the N-methyl-d-aspartate receptors complex in amyotrophic lateral sclerosis.
Alida Spalloni, Michele Nutini, Patrizia Longone. Biochim Biophys Acta 2013
Alida Spalloni, Michele Nutini, Patrizia Longone. Biochim Biophys Acta 2013
50
TDP-43 redistribution is an early event in sporadic amyotrophic lateral sclerosis.
Maria Teresa Giordana, Marco Piccinini, Silvia Grifoni, Giovanni De Marco, Marco Vercellino, Michela Magistrello, Alessia Pellerino, Barbara Buccinnà, Elisa Lupino, Maria Teresa Rinaudo. Brain Pathol 2010
Maria Teresa Giordana, Marco Piccinini, Silvia Grifoni, Giovanni De Marco, Marco Vercellino, Michela Magistrello, Alessia Pellerino, Barbara Buccinnà, Elisa Lupino, Maria Teresa Rinaudo. Brain Pathol 2010
50
Calpain is required for macroautophagy in mammalian cells.
Francesca Demarchi, Cosetta Bertoli, Tamara Copetti, Isei Tanida, Claudio Brancolini, Eeva-Liisa Eskelinen, Claudio Schneider. J Cell Biol 2006
Francesca Demarchi, Cosetta Bertoli, Tamara Copetti, Isei Tanida, Claudio Brancolini, Eeva-Liisa Eskelinen, Claudio Schneider. J Cell Biol 2006
50
Matrin 3 binds and stabilizes mRNA.
Maayan Salton, Ran Elkon, Tatiana Borodina, Aleksey Davydov, Marie-Laure Yaspo, Eran Halperin, Yosef Shiloh. PLoS One 2011
Maayan Salton, Ran Elkon, Tatiana Borodina, Aleksey Davydov, Marie-Laure Yaspo, Eran Halperin, Yosef Shiloh. PLoS One 2011
50
Distinct autophagosomal-lysosomal fusion mechanism revealed by thapsigargin-induced autophagy arrest.
Ian G Ganley, Pui-Mun Wong, Noor Gammoh, Xuejun Jiang. Mol Cell 2011
Ian G Ganley, Pui-Mun Wong, Noor Gammoh, Xuejun Jiang. Mol Cell 2011
50
Caspase-1 and -3 are sequentially activated in motor neuron death in Cu,Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis.
P Pasinelli, M K Houseweart, R H Brown, D W Cleveland. Proc Natl Acad Sci U S A 2000
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Poly(ADP-ribose) polymerase-1 cleavage during apoptosis: an update.
C Soldani, A Ivana Scovassi. Apoptosis 2002
C Soldani, A Ivana Scovassi. Apoptosis 2002
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Physiological significance of selective degradation of p62 by autophagy.
Masaaki Komatsu, Yoshinobu Ichimura. FEBS Lett 2010
Masaaki Komatsu, Yoshinobu Ichimura. FEBS Lett 2010
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The role of profilin complexes in cell motility and other cellular processes.
Walter Witke. Trends Cell Biol 2004
Walter Witke. Trends Cell Biol 2004
50
Multiple roles of TDP-43 in gene expression, splicing regulation, and human disease.
Emanuele Buratti, Francisco E Baralle. Front Biosci 2008
Emanuele Buratti, Francisco E Baralle. Front Biosci 2008
50
Apoptosis and autophagy: regulatory connections between two supposedly different processes.
Andrew Thorburn. Apoptosis 2008
Andrew Thorburn. Apoptosis 2008
50
The Pathobiology of TDP-43 C-Terminal Fragments in ALS and FTLD.
Britt A Berning, Adam K Walker. Front Neurosci 2019
Britt A Berning, Adam K Walker. Front Neurosci 2019
50
LC3- and p62-based biochemical methods for the analysis of autophagy progression in mammalian cells.
Peidu Jiang, Noboru Mizushima. Methods 2015
Peidu Jiang, Noboru Mizushima. Methods 2015
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Calcium: the Darth Vader of ALS.
S H Appel, D Beers, L Siklos, J I Engelhardt, D R Mosier. Amyotroph Lateral Scler Other Motor Neuron Disord 2001
S H Appel, D Beers, L Siklos, J I Engelhardt, D R Mosier. Amyotroph Lateral Scler Other Motor Neuron Disord 2001
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Caspase 6 has a protective role in SOD1(G93A) transgenic mice.
Marion C Hogg, Mollie R Mitchem, Hans-Georg König, Jochen H M Prehn. Biochim Biophys Acta 2016
Marion C Hogg, Mollie R Mitchem, Hans-Georg König, Jochen H M Prehn. Biochim Biophys Acta 2016
50
50
TDP-43-induced death is associated with altered regulation of BIM and Bcl-xL and attenuated by caspase-mediated TDP-43 cleavage.
Hiroaki Suzuki, Kikyo Lee, Masaaki Matsuoka. J Biol Chem 2011
Hiroaki Suzuki, Kikyo Lee, Masaaki Matsuoka. J Biol Chem 2011
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Expression of TDP-43 C-terminal Fragments in Vitro Recapitulates Pathological Features of TDP-43 Proteinopathies.
Lionel M Igaz, Linda K Kwong, Alice Chen-Plotkin, Matthew J Winton, Travis L Unger, Yan Xu, Manuela Neumann, John Q Trojanowski, Virginia M-Y Lee. J Biol Chem 2009
Lionel M Igaz, Linda K Kwong, Alice Chen-Plotkin, Matthew J Winton, Travis L Unger, Yan Xu, Manuela Neumann, John Q Trojanowski, Virginia M-Y Lee. J Biol Chem 2009
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Calcium dysregulation in amyotrophic lateral sclerosis.
Julian Grosskreutz, Ludo Van Den Bosch, Bernhard U Keller. Cell Calcium 2010
Julian Grosskreutz, Ludo Van Den Bosch, Bernhard U Keller. Cell Calcium 2010
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Going the Extra (Synaptic) Mile: Excitotoxicity as the Road Toward Neurodegenerative Diseases.
Adam Armada-Moreira, Joana I Gomes, Carolina Campos Pina, Oksana K Savchak, Joana Gonçalves-Ribeiro, Nádia Rei, Sara Pinto, Tatiana P Morais, Robertta Silva Martins, Filipa F Ribeiro,[...]. Front Cell Neurosci 2020
Adam Armada-Moreira, Joana I Gomes, Carolina Campos Pina, Oksana K Savchak, Joana Gonçalves-Ribeiro, Nádia Rei, Sara Pinto, Tatiana P Morais, Robertta Silva Martins, Filipa F Ribeiro,[...]. Front Cell Neurosci 2020
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Molecular mechanisms of caspase regulation during apoptosis.
Stefan J Riedl, Yigong Shi. Nat Rev Mol Cell Biol 2004
Stefan J Riedl, Yigong Shi. Nat Rev Mol Cell Biol 2004
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The in vitro cleavage of the hAtg proteins by cell death proteases.
Joanna M Norman, Gerald M Cohen, Edward T W Bampton. Autophagy 2010
Joanna M Norman, Gerald M Cohen, Edward T W Bampton. Autophagy 2010
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