Laura E Russell, Yitian Zhou, Ahmed A Almousa, Jasleen K Sodhi, Chukwunonso K Nwabufo, Volker M Lauschke. Drug Metab Rev 2021
Times Cited: 11
Times Cited: 11
Times Cited
Times Co-cited
Similarity
Pharmacogenomic Biomarkers for Improved Drug Therapy-Recent Progress and Future Developments.
Volker M Lauschke, Lili Milani, Magnus Ingelman-Sundberg. AAPS J 2017
Volker M Lauschke, Lili Milani, Magnus Ingelman-Sundberg. AAPS J 2017
63
Genetic variation in the human cytochrome P450 supergene family.
Kohei Fujikura, Magnus Ingelman-Sundberg, Volker M Lauschke. Pharmacogenet Genomics 2015
Kohei Fujikura, Magnus Ingelman-Sundberg, Volker M Lauschke. Pharmacogenet Genomics 2015
45
Integrating rare genetic variants into pharmacogenetic drug response predictions.
Magnus Ingelman-Sundberg, Souren Mkrtchian, Yitian Zhou, Volker M Lauschke. Hum Genomics 2018
Magnus Ingelman-Sundberg, Souren Mkrtchian, Yitian Zhou, Volker M Lauschke. Hum Genomics 2018
45
Population-scale predictions of DPD and TPMT phenotypes using a quantitative pharmacogene-specific ensemble classifier.
Yitian Zhou, Carolina Dagli Hernandez, Volker M Lauschke. Br J Cancer 2020
Yitian Zhou, Carolina Dagli Hernandez, Volker M Lauschke. Br J Cancer 2020
36
Rare genetic variants in cellular transporters, metabolic enzymes, and nuclear receptors can be important determinants of interindividual differences in drug response.
Mikael Kozyra, Magnus Ingelman-Sundberg, Volker M Lauschke. Genet Med 2017
Mikael Kozyra, Magnus Ingelman-Sundberg, Volker M Lauschke. Genet Med 2017
36
An optimized prediction framework to assess the functional impact of pharmacogenetic variants.
Yitian Zhou, Souren Mkrtchian, Masaki Kumondai, Masahiro Hiratsuka, Volker M Lauschke. Pharmacogenomics J 2019
Yitian Zhou, Souren Mkrtchian, Masaki Kumondai, Masahiro Hiratsuka, Volker M Lauschke. Pharmacogenomics J 2019
36
Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation.
Ulrich M Zanger, Matthias Schwab. Pharmacol Ther 2013
Ulrich M Zanger, Matthias Schwab. Pharmacol Ther 2013
36
Pharmacogenomics of drug-metabolizing enzymes: a recent update on clinical implications and endogenous effects.
S C Sim, M Kacevska, M Ingelman-Sundberg. Pharmacogenomics J 2013
S C Sim, M Kacevska, M Ingelman-Sundberg. Pharmacogenomics J 2013
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Computational Methods for the Pharmacogenetic Interpretation of Next Generation Sequencing Data.
Yitian Zhou, Kohei Fujikura, Souren Mkrtchian, Volker M Lauschke. Front Pharmacol 2018
Yitian Zhou, Kohei Fujikura, Souren Mkrtchian, Volker M Lauschke. Front Pharmacol 2018
27
Ethnogeographic and inter-individual variability of human ABC transporters.
Qingyang Xiao, Yitian Zhou, Volker M Lauschke. Hum Genet 2020
Qingyang Xiao, Yitian Zhou, Volker M Lauschke. Hum Genet 2020
27
A method and server for predicting damaging missense mutations.
Ivan A Adzhubei, Steffen Schmidt, Leonid Peshkin, Vasily E Ramensky, Anna Gerasimova, Peer Bork, Alexey S Kondrashov, Shamil R Sunyaev. Nat Methods 2010
Ivan A Adzhubei, Steffen Schmidt, Leonid Peshkin, Vasily E Ramensky, Anna Gerasimova, Peer Bork, Alexey S Kondrashov, Shamil R Sunyaev. Nat Methods 2010
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Worldwide Distribution of Cytochrome P450 Alleles: A Meta-analysis of Population-scale Sequencing Projects.
Y Zhou, M Ingelman-Sundberg, V M Lauschke. Clin Pharmacol Ther 2017
Y Zhou, M Ingelman-Sundberg, V M Lauschke. Clin Pharmacol Ther 2017
27
PharmVar GeneFocus: CYP2D6.
Charity Nofziger, Amy J Turner, Katrin Sangkuhl, Michelle Whirl-Carrillo, José A G Agúndez, John L Black, Henry M Dunnenberger, Gualberto Ruano, Martin A Kennedy, Michael S Phillips,[...]. Clin Pharmacol Ther 2020
Charity Nofziger, Amy J Turner, Katrin Sangkuhl, Michelle Whirl-Carrillo, José A G Agúndez, John L Black, Henry M Dunnenberger, Gualberto Ruano, Martin A Kennedy, Michael S Phillips,[...]. Clin Pharmacol Ther 2020
27
A general framework for estimating the relative pathogenicity of human genetic variants.
Martin Kircher, Daniela M Witten, Preti Jain, Brian J O'Roak, Gregory M Cooper, Jay Shendure. Nat Genet 2014
Martin Kircher, Daniela M Witten, Preti Jain, Brian J O'Roak, Gregory M Cooper, Jay Shendure. Nat Genet 2014
27
Quantifying rare, deleterious variation in 12 human cytochrome P450 drug-metabolism genes in a large-scale exome dataset.
Adam S Gordon, Holly K Tabor, Andrew D Johnson, Beverly M Snively, Themistocles L Assimes, Paul L Auer, John P A Ioannidis, Ulrike Peters, Jennifer G Robinson, Lara E Sucheston,[...]. Hum Mol Genet 2014
Adam S Gordon, Holly K Tabor, Andrew D Johnson, Beverly M Snively, Themistocles L Assimes, Paul L Auer, John P A Ioannidis, Ulrike Peters, Jennifer G Robinson, Lara E Sucheston,[...]. Hum Mol Genet 2014
27
Prediction of drug response and adverse drug reactions: From twin studies to Next Generation Sequencing.
Volker M Lauschke, Magnus Ingelman-Sundberg. Eur J Pharm Sci 2019
Volker M Lauschke, Magnus Ingelman-Sundberg. Eur J Pharm Sci 2019
27
Gene-Specific Variant Classifier (DPYD-Varifier) to Identify Deleterious Alleles of Dihydropyrimidine Dehydrogenase.
Shikshya Shrestha, Cheng Zhang, Calvin R Jerde, Qian Nie, Hu Li, Steven M Offer, Robert B Diasio. Clin Pharmacol Ther 2018
Shikshya Shrestha, Cheng Zhang, Calvin R Jerde, Qian Nie, Hu Li, Steven M Offer, Robert B Diasio. Clin Pharmacol Ther 2018
27
Pharmacogenetics in Psychiatry: An Update on Clinical Usability.
Ron H N van Schaik, Daniel J Müller, Alessandro Serretti, Magnus Ingelman-Sundberg. Front Pharmacol 2020
Ron H N van Schaik, Daniel J Müller, Alessandro Serretti, Magnus Ingelman-Sundberg. Front Pharmacol 2020
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The Clinical Pharmacogenetics Implementation Consortium: 10 Years Later.
Mary V Relling, Teri E Klein, Roseann S Gammal, Michelle Whirl-Carrillo, James M Hoffman, Kelly E Caudle. Clin Pharmacol Ther 2020
Mary V Relling, Teri E Klein, Roseann S Gammal, Michelle Whirl-Carrillo, James M Hoffman, Kelly E Caudle. Clin Pharmacol Ther 2020
27
Translating genotype data of 44,000 biobank participants into clinical pharmacogenetic recommendations: challenges and solutions.
Sulev Reisberg, Kristi Krebs, Maarja Lepamets, Mart Kals, Reedik Mägi, Kristjan Metsalu, Volker M Lauschke, Jaak Vilo, Lili Milani. Genet Med 2019
Sulev Reisberg, Kristi Krebs, Maarja Lepamets, Mart Kals, Reedik Mägi, Kristjan Metsalu, Volker M Lauschke, Jaak Vilo, Lili Milani. Genet Med 2019
27
Genetic variation in human drug-related genes.
Charlotta Pauline Irmgard Schärfe, Roman Tremmel, Matthias Schwab, Oliver Kohlbacher, Debora Susan Marks. Genome Med 2017
Charlotta Pauline Irmgard Schärfe, Roman Tremmel, Matthias Schwab, Oliver Kohlbacher, Debora Susan Marks. Genome Med 2017
27
The genetic landscape of the human solute carrier (SLC) transporter superfamily.
Lena Schaller, Volker M Lauschke. Hum Genet 2019
Lena Schaller, Volker M Lauschke. Hum Genet 2019
27
Requirements for comprehensive pharmacogenetic genotyping platforms.
Volker M Lauschke, Magnus Ingelman-Sundberg. Pharmacogenomics 2016
Volker M Lauschke, Magnus Ingelman-Sundberg. Pharmacogenomics 2016
27
Rare genetic variability in human drug target genes modulates drug response and can guide precision medicine.
Yitian Zhou, Gabriel Herras Arribas, Ainoleena Turku, Tuuli Jürgenson, Souren Mkrtchian, Kristi Krebs, Yi Wang, Barbora Svobodova, Lili Milani, Gunnar Schulte,[...]. Sci Adv 2021
Yitian Zhou, Gabriel Herras Arribas, Ainoleena Turku, Tuuli Jürgenson, Souren Mkrtchian, Kristi Krebs, Yi Wang, Barbora Svobodova, Lili Milani, Gunnar Schulte,[...]. Sci Adv 2021
37
Global Frequencies of Clinically Important HLA Alleles and Their Implications For the Cost-Effectiveness of Preemptive Pharmacogenetic Testing.
Yitian Zhou, Kristi Krebs, Lili Milani, Volker M Lauschke. Clin Pharmacol Ther 2021
Yitian Zhou, Kristi Krebs, Lili Milani, Volker M Lauschke. Clin Pharmacol Ther 2021
27
A global reference for human genetic variation.
Adam Auton, Lisa D Brooks, Richard M Durbin, Erik P Garrison, Hyun Min Kang, Jan O Korbel, Jonathan L Marchini, Shane McCarthy, Gil A McVean, Gonçalo R Abecasis. Nature 2015
Adam Auton, Lisa D Brooks, Richard M Durbin, Erik P Garrison, Hyun Min Kang, Jan O Korbel, Jonathan L Marchini, Shane McCarthy, Gil A McVean, Gonçalo R Abecasis. Nature 2015
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Heritability of metoprolol and torsemide pharmacokinetics.
J Matthaei, J Brockmöller, M V Tzvetkov, D Sehrt, C Sachse-Seeboth, J B Hjelmborg, S Möller, U Halekoh, U Hofmann, M Schwab,[...]. Clin Pharmacol Ther 2015
J Matthaei, J Brockmöller, M V Tzvetkov, D Sehrt, C Sachse-Seeboth, J B Hjelmborg, S Möller, U Halekoh, U Hofmann, M Schwab,[...]. Clin Pharmacol Ther 2015
27
The global spectrum of protein-coding pharmacogenomic diversity.
G E B Wright, B Carleton, M R Hayden, C J D Ross. Pharmacogenomics J 2018
G E B Wright, B Carleton, M R Hayden, C J D Ross. Pharmacogenomics J 2018
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An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people.
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27
The mutational constraint spectrum quantified from variation in 141,456 humans.
Konrad J Karczewski, Laurent C Francioli, Grace Tiao, Beryl B Cummings, Jessica Alföldi, Qingbo Wang, Ryan L Collins, Kristen M Laricchia, Andrea Ganna, Daniel P Birnbaum,[...]. Nature 2020
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18
The evaluation of tools used to predict the impact of missense variants is hindered by two types of circularity.
Dominik G Grimm, Chloé-Agathe Azencott, Fabian Aicheler, Udo Gieraths, Daniel G MacArthur, Kaitlin E Samocha, David N Cooper, Peter D Stenson, Mark J Daly, Jordan W Smoller,[...]. Hum Mutat 2015
Dominik G Grimm, Chloé-Agathe Azencott, Fabian Aicheler, Udo Gieraths, Daniel G MacArthur, Kaitlin E Samocha, David N Cooper, Peter D Stenson, Mark J Daly, Jordan W Smoller,[...]. Hum Mutat 2015
18
Transfer learning enables prediction of CYP2D6 haplotype function.
Gregory McInnes, Rachel Dalton, Katrin Sangkuhl, Michelle Whirl-Carrillo, Seung-Been Lee, Philip S Tsao, Andrea Gaedigk, Russ B Altman, Erica L Woodahl. PLoS Comput Biol 2020
Gregory McInnes, Rachel Dalton, Katrin Sangkuhl, Michelle Whirl-Carrillo, Seung-Been Lee, Philip S Tsao, Andrea Gaedigk, Russ B Altman, Erica L Woodahl. PLoS Comput Biol 2020
18
PharmVar GeneFocus: CYP2B6.
Zeruesenay Desta, Ahmed El-Boraie, Li Gong, Andrew A Somogyi, Volker M Lauschke, Collet Dandara, Kathrin Klein, Neil A Miller, Teri E Klein, Rachel F Tyndale,[...]. Clin Pharmacol Ther 2021
Zeruesenay Desta, Ahmed El-Boraie, Li Gong, Andrew A Somogyi, Volker M Lauschke, Collet Dandara, Kathrin Klein, Neil A Miller, Teri E Klein, Rachel F Tyndale,[...]. Clin Pharmacol Ther 2021
18
Systematic Computational Identification of Variants That Activate Exonic and Intronic Cryptic Splice Sites.
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Maximum entropy modeling of short sequence motifs with applications to RNA splicing signals.
Gene Yeo, Christopher B Burge. J Comput Biol 2004
Gene Yeo, Christopher B Burge. J Comput Biol 2004
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REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants.
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Nilah M Ioannidis, Joseph H Rothstein, Vikas Pejaver, Sumit Middha, Shannon K McDonnell, Saurabh Baheti, Anthony Musolf, Qing Li, Emily Holzinger, Danielle Karyadi,[...]. Am J Hum Genet 2016
18
Impact of NUDT15 genetics on severe thiopurine-related hematotoxicity in patients with European ancestry.
Elke Schaeffeler, Simon U Jaeger, Verena Klumpp, Jun J Yang, Svitlana Igel, Laura Hinze, Martin Stanulla, Matthias Schwab. Genet Med 2019
Elke Schaeffeler, Simon U Jaeger, Verena Klumpp, Jun J Yang, Svitlana Igel, Laura Hinze, Martin Stanulla, Matthias Schwab. Genet Med 2019
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Emerging strategies to bridge the gap between pharmacogenomic research and its clinical implementation.
Volker M Lauschke, Magnus Ingelman-Sundberg. NPJ Genom Med 2020
Volker M Lauschke, Magnus Ingelman-Sundberg. NPJ Genom Med 2020
18
Pharmacogenetic allele nomenclature: International workgroup recommendations for test result reporting.
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18
MMSplice: modular modeling improves the predictions of genetic variant effects on splicing.
Jun Cheng, Thi Yen Duong Nguyen, Kamil J Cygan, Muhammed Hasan Çelik, William G Fairbrother, Žiga Avsec, Julien Gagneur. Genome Biol 2019
Jun Cheng, Thi Yen Duong Nguyen, Kamil J Cygan, Muhammed Hasan Çelik, William G Fairbrother, Žiga Avsec, Julien Gagneur. Genome Biol 2019
18
Predicting the functional effect of amino acid substitutions and indels.
Yongwook Choi, Gregory E Sims, Sean Murphy, Jason R Miller, Agnes P Chan. PLoS One 2012
Yongwook Choi, Gregory E Sims, Sean Murphy, Jason R Miller, Agnes P Chan. PLoS One 2012
18
Predicting effects of noncoding variants with deep learning-based sequence model.
Jian Zhou, Olga G Troyanskaya. Nat Methods 2015
Jian Zhou, Olga G Troyanskaya. Nat Methods 2015
18
Bi-directional SIFT predicts a subset of activating mutations.
William Lee, Yan Zhang, Kiran Mukhyala, Robert A Lazarus, Zemin Zhang. PLoS One 2009
William Lee, Yan Zhang, Kiran Mukhyala, Robert A Lazarus, Zemin Zhang. PLoS One 2009
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Predicting Splicing from Primary Sequence with Deep Learning.
Kishore Jaganathan, Sofia Kyriazopoulou Panagiotopoulou, Jeremy F McRae, Siavash Fazel Darbandi, David Knowles, Yang I Li, Jack A Kosmicki, Juan Arbelaez, Wenwu Cui, Grace B Schwartz,[...]. Cell 2019
Kishore Jaganathan, Sofia Kyriazopoulou Panagiotopoulou, Jeremy F McRae, Siavash Fazel Darbandi, David Knowles, Yang I Li, Jack A Kosmicki, Juan Arbelaez, Wenwu Cui, Grace B Schwartz,[...]. Cell 2019
18
A spectral approach integrating functional genomic annotations for coding and noncoding variants.
Iuliana Ionita-Laza, Kenneth McCallum, Bin Xu, Joseph D Buxbaum. Nat Genet 2016
Iuliana Ionita-Laza, Kenneth McCallum, Bin Xu, Joseph D Buxbaum. Nat Genet 2016
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A method to predict the impact of regulatory variants from DNA sequence.
Dongwon Lee, David U Gorkin, Maggie Baker, Benjamin J Strober, Alessandro L Asoni, Andrew S McCallion, Michael A Beer. Nat Genet 2015
Dongwon Lee, David U Gorkin, Maggie Baker, Benjamin J Strober, Alessandro L Asoni, Andrew S McCallion, Michael A Beer. Nat Genet 2015
18
Tandem mass spectrometric analysis of novel caffeine scaffold-based bifunctional compounds for Parkinson's disease.
Chukwunonso K Nwabufo, Anas El-Aneed, Ed S Krol. Rapid Commun Mass Spectrom 2019
Chukwunonso K Nwabufo, Anas El-Aneed, Ed S Krol. Rapid Commun Mass Spectrom 2019
28
Introduction to the mini special issue on next generation drug discovery and development: rethinking translational pharmacology for accelerated drug development.
Chukwunonso K Nwabufo. Drug Metab Rev 2021
Chukwunonso K Nwabufo. Drug Metab Rev 2021
50
Pharmacogenetic tests and depressive symptom remission: a meta-analysis of randomized controlled trials.
Chad A Bousman, Katarina Arandjelovic, Serafino G Mancuso, Harris A Eyre, Boadie W Dunlop. Pharmacogenomics 2019
Chad A Bousman, Katarina Arandjelovic, Serafino G Mancuso, Harris A Eyre, Boadie W Dunlop. Pharmacogenomics 2019
18
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.