Yanfen Zhu, Amit D Gujar, Chee-Hong Wong, Harianto Tjong, Chew Yee Ngan, Liang Gong, Yi-An Chen, Hoon Kim, Jihe Liu, Meihong Li, Adam Mil-Homens, Rahul Maurya, Chris Kuhlberg, Fanyue Sun, Eunhee Yi, Ana C deCarvalho, Yijun Ruan, Roel G W Verhaak, Chia-Lin Wei. Cancer Cell 2021
Times Cited: 26
Times Cited: 26
Times Cited
Times Co-cited
Similarity
Circular ecDNA promotes accessible chromatin and high oncogene expression.
Sihan Wu, Kristen M Turner, Nam Nguyen, Ramya Raviram, Marcella Erb, Jennifer Santini, Jens Luebeck, Utkrisht Rajkumar, Yarui Diao, Bin Li,[...]. Nature 2019
Sihan Wu, Kristen M Turner, Nam Nguyen, Ramya Raviram, Marcella Erb, Jennifer Santini, Jens Luebeck, Utkrisht Rajkumar, Yarui Diao, Bin Li,[...]. Nature 2019
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Functional Enhancers Shape Extrachromosomal Oncogene Amplifications.
Andrew R Morton, Nergiz Dogan-Artun, Zachary J Faber, Graham MacLeod, Cynthia F Bartels, Megan S Piazza, Kevin C Allan, Stephen C Mack, Xiuxing Wang, Ryan C Gimple,[...]. Cell 2019
Andrew R Morton, Nergiz Dogan-Artun, Zachary J Faber, Graham MacLeod, Cynthia F Bartels, Megan S Piazza, Kevin C Allan, Stephen C Mack, Xiuxing Wang, Ryan C Gimple,[...]. Cell 2019
69
Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers.
Hoon Kim, Nam-Phuong Nguyen, Kristen Turner, Sihan Wu, Amit D Gujar, Jens Luebeck, Jihe Liu, Viraj Deshpande, Utkrisht Rajkumar, Sandeep Namburi,[...]. Nat Genet 2020
Hoon Kim, Nam-Phuong Nguyen, Kristen Turner, Sihan Wu, Amit D Gujar, Jens Luebeck, Jihe Liu, Viraj Deshpande, Utkrisht Rajkumar, Sandeep Namburi,[...]. Nat Genet 2020
69
Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA.
David A Nathanson, Beatrice Gini, Jack Mottahedeh, Koppany Visnyei, Tomoyuki Koga, German Gomez, Ascia Eskin, Kiwook Hwang, Jun Wang, Kenta Masui,[...]. Science 2014
David A Nathanson, Beatrice Gini, Jack Mottahedeh, Koppany Visnyei, Tomoyuki Koga, German Gomez, Ascia Eskin, Kiwook Hwang, Jun Wang, Kenta Masui,[...]. Science 2014
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Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity.
Kristen M Turner, Viraj Deshpande, Doruk Beyter, Tomoyuki Koga, Jessica Rusert, Catherine Lee, Bin Li, Karen Arden, Bing Ren, David A Nathanson,[...]. Nature 2017
Kristen M Turner, Viraj Deshpande, Doruk Beyter, Tomoyuki Koga, Jessica Rusert, Catherine Lee, Bin Li, Karen Arden, Bing Ren, David A Nathanson,[...]. Nature 2017
57
Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma.
Richard P Koche, Elias Rodriguez-Fos, Konstantin Helmsauer, Martin Burkert, Ian C MacArthur, Jesper Maag, Rocio Chamorro, Natalia Munoz-Perez, Montserrat Puiggròs, Heathcliff Dorado Garcia,[...]. Nat Genet 2020
Richard P Koche, Elias Rodriguez-Fos, Konstantin Helmsauer, Martin Burkert, Ian C MacArthur, Jesper Maag, Rocio Chamorro, Natalia Munoz-Perez, Montserrat Puiggròs, Heathcliff Dorado Garcia,[...]. Nat Genet 2020
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MINUTE CHROMATIN BODIES IN MALIGNANT TUMOURS OF CHILDHOOD.
D COX, C YUNCKEN, A I SPRIGGS. Lancet 1965
D COX, C YUNCKEN, A I SPRIGGS. Lancet 1965
46
Extrachromosomal oncogene amplification in tumour pathogenesis and evolution.
Roel G W Verhaak, Vineet Bafna, Paul S Mischel. Nat Rev Cancer 2019
Roel G W Verhaak, Vineet Bafna, Paul S Mischel. Nat Rev Cancer 2019
46
Exploring the landscape of focal amplifications in cancer using AmpliconArchitect.
Viraj Deshpande, Jens Luebeck, Nam-Phuong D Nguyen, Mehrdad Bakhtiari, Kristen M Turner, Richard Schwab, Hannah Carter, Paul S Mischel, Vineet Bafna. Nat Commun 2019
Viraj Deshpande, Jens Luebeck, Nam-Phuong D Nguyen, Mehrdad Bakhtiari, Kristen M Turner, Richard Schwab, Hannah Carter, Paul S Mischel, Vineet Bafna. Nat Commun 2019
42
Double minute chromosomes can be produced from precursors derived from a chromosomal deletion.
S M Carroll, M L DeRose, P Gaudray, C M Moore, D R Needham-Vandevanter, D D Von Hoff, G M Wahl. Mol Cell Biol 1988
S M Carroll, M L DeRose, P Gaudray, C M Moore, D R Needham-Vandevanter, D D Von Hoff, G M Wahl. Mol Cell Biol 1988
42
ecDNA hubs drive cooperative intermolecular oncogene expression.
King L Hung, Kathryn E Yost, Liangqi Xie, Quanming Shi, Konstantin Helmsauer, Jens Luebeck, Robert Schöpflin, Joshua T Lange, Rocío Chamorro González, Natasha E Weiser,[...]. Nature 2021
King L Hung, Kathryn E Yost, Liangqi Xie, Quanming Shi, Konstantin Helmsauer, Jens Luebeck, Robert Schöpflin, Joshua T Lange, Rocío Chamorro González, Natasha E Weiser,[...]. Nature 2021
64
Enhancer hijacking determines extrachromosomal circular MYCN amplicon architecture in neuroblastoma.
Konstantin Helmsauer, Maria E Valieva, Salaheddine Ali, Rocío Chamorro González, Robert Schöpflin, Claudia Röefzaad, Yi Bei, Heathcliff Dorado Garcia, Elias Rodriguez-Fos, Montserrat Puiggròs,[...]. Nat Commun 2020
Konstantin Helmsauer, Maria E Valieva, Salaheddine Ali, Rocío Chamorro González, Robert Schöpflin, Claudia Röefzaad, Yi Bei, Heathcliff Dorado Garcia, Elias Rodriguez-Fos, Montserrat Puiggròs,[...]. Nat Commun 2020
42
Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in glioblastoma.
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38
Normal and Cancerous Tissues Release Extrachromosomal Circular DNA (eccDNA) into the Circulation.
Pankaj Kumar, Laura W Dillon, Yoshiyuki Shibata, Amir A Jazaeri, David R Jones, Anindya Dutta. Mol Cancer Res 2017
Pankaj Kumar, Laura W Dillon, Yoshiyuki Shibata, Amir A Jazaeri, David R Jones, Anindya Dutta. Mol Cancer Res 2017
34
Chromothripsis drives the evolution of gene amplification in cancer.
Ofer Shoshani, Simon F Brunner, Rona Yaeger, Peter Ly, Yael Nechemia-Arbely, Dong Hyun Kim, Rongxin Fang, Guillaume A Castillon, Miao Yu, Julia S Z Li,[...]. Nature 2021
Ofer Shoshani, Simon F Brunner, Rona Yaeger, Peter Ly, Yael Nechemia-Arbely, Dong Hyun Kim, Rongxin Fang, Guillaume A Castillon, Miao Yu, Julia S Z Li,[...]. Nature 2021
34
Double-strand breakage in the extrachromosomal double minutes triggers their aggregation in the nucleus, micronucleation, and morphological transformation.
Yoshihiro Oobatake, Noriaki Shimizu. Genes Chromosomes Cancer 2020
Yoshihiro Oobatake, Noriaki Shimizu. Genes Chromosomes Cancer 2020
39
Gene amplification as double minutes or homogeneously staining regions in solid tumors: origin and structure.
Clelia Tiziana Storlazzi, Angelo Lonoce, Maria C Guastadisegni, Domenico Trombetta, Pietro D'Addabbo, Giulia Daniele, Alberto L'Abbate, Gemma Macchia, Cecilia Surace, Klaas Kok,[...]. Genome Res 2010
Clelia Tiziana Storlazzi, Angelo Lonoce, Maria C Guastadisegni, Domenico Trombetta, Pietro D'Addabbo, Giulia Daniele, Alberto L'Abbate, Gemma Macchia, Cecilia Surace, Klaas Kok,[...]. Genome Res 2010
34
Production of Extrachromosomal MicroDNAs Is Linked to Mismatch Repair Pathways and Transcriptional Activity.
Laura W Dillon, Pankaj Kumar, Yoshiyuki Shibata, Yuh-Hwa Wang, Smaranda Willcox, Jack D Griffith, Yves Pommier, Shunichi Takeda, Anindya Dutta. Cell Rep 2015
Laura W Dillon, Pankaj Kumar, Yoshiyuki Shibata, Yuh-Hwa Wang, Smaranda Willcox, Jack D Griffith, Yves Pommier, Shunichi Takeda, Anindya Dutta. Cell Rep 2015
30
Extrachromosomal microDNAs and chromosomal microdeletions in normal tissues.
Yoshiyuki Shibata, Pankaj Kumar, Ryan Layer, Smaranda Willcox, Jeffrey R Gagan, Jack D Griffith, Anindya Dutta. Science 2012
Yoshiyuki Shibata, Pankaj Kumar, Ryan Layer, Smaranda Willcox, Jeffrey R Gagan, Jack D Griffith, Anindya Dutta. Science 2012
30
eccDNAs are apoptotic products with high innate immunostimulatory activity.
Yuangao Wang, Meng Wang, Mohamed Nadhir Djekidel, Huan Chen, Di Liu, Frederick W Alt, Yi Zhang. Nature 2021
Yuangao Wang, Meng Wang, Mohamed Nadhir Djekidel, Huan Chen, Di Liu, Frederick W Alt, Yi Zhang. Nature 2021
61
Extrachromosomal DNA-relieving heredity constraints, accelerating tumour evolution.
C Bailey, M J Shoura, P S Mischel, C Swanton. Ann Oncol 2020
C Bailey, M J Shoura, P S Mischel, C Swanton. Ann Oncol 2020
26
ATAC-seq identifies thousands of extrachromosomal circular DNA in cancer and cell lines.
Pankaj Kumar, Shashi Kiran, Shekhar Saha, Zhangli Su, Teressa Paulsen, Ajay Chatrath, Yoshiyuki Shibata, Etsuko Shibata, Anindya Dutta. Sci Adv 2020
Pankaj Kumar, Shashi Kiran, Shekhar Saha, Zhangli Su, Teressa Paulsen, Ajay Chatrath, Yoshiyuki Shibata, Etsuko Shibata, Anindya Dutta. Sci Adv 2020
26
Transcription-induced formation of extrachromosomal DNA during yeast ageing.
Ryan M Hull, Michelle King, Grazia Pizza, Felix Krueger, Xabier Vergara, Jonathan Houseley. PLoS Biol 2019
Ryan M Hull, Michelle King, Grazia Pizza, Felix Krueger, Xabier Vergara, Jonathan Houseley. PLoS Biol 2019
26
MOLECULAR SIZE AND CIRCULARITY OF DNA IN CELLS OF MAMMALS AND HIGHER PLANTS.
Y HOTTA, A BASSEL. Proc Natl Acad Sci U S A 1965
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26
Circular DNA elements of chromosomal origin are common in healthy human somatic tissue.
Henrik Devitt Møller, Marghoob Mohiyuddin, Iñigo Prada-Luengo, M Reza Sailani, Jens Frey Halling, Peter Plomgaard, Lasse Maretty, Anders Johannes Hansen, Michael P Snyder, Henriette Pilegaard,[...]. Nat Commun 2018
Henrik Devitt Møller, Marghoob Mohiyuddin, Iñigo Prada-Luengo, M Reza Sailani, Jens Frey Halling, Peter Plomgaard, Lasse Maretty, Anders Johannes Hansen, Michael P Snyder, Henriette Pilegaard,[...]. Nat Commun 2018
26
MYC-containing double minutes in hematologic malignancies: evidence in favor of the episome model and exclusion of MYC as the target gene.
Clelia Tiziana Storlazzi, Thoas Fioretos, Cecilia Surace, Angelo Lonoce, Angela Mastrorilli, Bodil Strömbeck, Pietro D'Addabbo, Francesco Iacovelli, Crescenzio Minervini, Anna Aventin,[...]. Hum Mol Genet 2006
Clelia Tiziana Storlazzi, Thoas Fioretos, Cecilia Surace, Angelo Lonoce, Angela Mastrorilli, Bodil Strömbeck, Pietro D'Addabbo, Francesco Iacovelli, Crescenzio Minervini, Anna Aventin,[...]. Hum Mol Genet 2006
26
Small extrachromosomal circular DNAs, microDNA, produce short regulatory RNAs that suppress gene expression independent of canonical promoters.
Teressa Paulsen, Yoshiyuki Shibata, Pankaj Kumar, Laura Dillon, Anindya Dutta. Nucleic Acids Res 2019
Teressa Paulsen, Yoshiyuki Shibata, Pankaj Kumar, Laura Dillon, Anindya Dutta. Nucleic Acids Res 2019
26
26
Genomic organization and evolution of double minutes/homogeneously staining regions with MYC amplification in human cancer.
Alberto L'Abbate, Gemma Macchia, Pietro D'Addabbo, Angelo Lonoce, Doron Tolomeo, Domenico Trombetta, Klaas Kok, Christoph Bartenhagen, Christopher W Whelan, Orazio Palumbo,[...]. Nucleic Acids Res 2014
Alberto L'Abbate, Gemma Macchia, Pietro D'Addabbo, Angelo Lonoce, Doron Tolomeo, Domenico Trombetta, Klaas Kok, Christoph Bartenhagen, Christopher W Whelan, Orazio Palumbo,[...]. Nucleic Acids Res 2014
26
AmpliconReconstructor integrates NGS and optical mapping to resolve the complex structures of focal amplifications.
Jens Luebeck, Ceyda Coruh, Siavash R Dehkordi, Joshua T Lange, Kristen M Turner, Viraj Deshpande, Dave A Pai, Chao Zhang, Utkrisht Rajkumar, Julie A Law,[...]. Nat Commun 2020
Jens Luebeck, Ceyda Coruh, Siavash R Dehkordi, Joshua T Lange, Kristen M Turner, Viraj Deshpande, Dave A Pai, Chao Zhang, Utkrisht Rajkumar, Julie A Law,[...]. Nat Commun 2020
42
Molecular structure of double-minute chromosomes bearing amplified copies of the epidermal growth factor receptor gene in gliomas.
Nicolas Vogt, Sandrine-Hélène Lefèvre, Françoise Apiou, Anne-Marie Dutrillaux, Andrej Cör, Pascal Leuraud, Marie-France Poupon, Bernard Dutrillaux, Michelle Debatisse, Bernard Malfoy. Proc Natl Acad Sci U S A 2004
Nicolas Vogt, Sandrine-Hélène Lefèvre, Françoise Apiou, Anne-Marie Dutrillaux, Andrej Cör, Pascal Leuraud, Marie-France Poupon, Bernard Dutrillaux, Michelle Debatisse, Bernard Malfoy. Proc Natl Acad Sci U S A 2004
23
Inhibiting homologous recombination decreases extrachromosomal amplification but has no effect on intrachromosomal amplification in methotrexate-resistant colon cancer cells.
Mengdi Cai, Huishu Zhang, Liqing Hou, Wei Gao, Ying Song, Xiaobo Cui, Chunxiang Li, Rongwei Guan, Jinfa Ma, Xu Wang,[...]. Int J Cancer 2019
Mengdi Cai, Huishu Zhang, Liqing Hou, Wei Gao, Ying Song, Xiaobo Cui, Chunxiang Li, Rongwei Guan, Jinfa Ma, Xu Wang,[...]. Int J Cancer 2019
25
Discoveries of Extrachromosomal Circles of DNA in Normal and Tumor Cells.
Teressa Paulsen, Pankaj Kumar, M Murat Koseoglu, Anindya Dutta. Trends Genet 2018
Teressa Paulsen, Pankaj Kumar, M Murat Koseoglu, Anindya Dutta. Trends Genet 2018
23
Classification of extrachromosomal circular DNA with a focus on the role of extrachromosomal DNA (ecDNA) in tumor heterogeneity and progression.
Zhenyu Liao, Wang Jiang, Longyun Ye, Tianjiao Li, Xianjun Yu, Liang Liu. Biochim Biophys Acta Rev Cancer 2020
Zhenyu Liao, Wang Jiang, Longyun Ye, Tianjiao Li, Xianjun Yu, Liang Liu. Biochim Biophys Acta Rev Cancer 2020
23
Transposition and amplification of oncogene-related sequences in human neuroblastomas.
N E Kohl, N Kanda, R R Schreck, G Bruns, S A Latt, F Gilbert, F W Alt. Cell 1983
N E Kohl, N Kanda, R R Schreck, G Bruns, S A Latt, F Gilbert, F W Alt. Cell 1983
19
Programmed genome rearrangements in Oxytricha produce transcriptionally active extrachromosomal circular DNA.
V Talya Yerlici, Michael W Lu, Carla R Hoge, Richard V Miller, Rafik Neme, Jaspreet S Khurana, John R Bracht, Laura F Landweber. Nucleic Acids Res 2019
V Talya Yerlici, Michael W Lu, Carla R Hoge, Richard V Miller, Rafik Neme, Jaspreet S Khurana, John R Bracht, Laura F Landweber. Nucleic Acids Res 2019
33
Identification and characterization of extrachromosomal circular DNA in maternal plasma.
Sarah T K Sin, Peiyong Jiang, Jiaen Deng, Lu Ji, Suk Hang Cheng, Anindya Dutta, Tak Y Leung, K C Allen Chan, Rossa W K Chiu, Y M Dennis Lo. Proc Natl Acad Sci U S A 2020
Sarah T K Sin, Peiyong Jiang, Jiaen Deng, Lu Ji, Suk Hang Cheng, Anindya Dutta, Tak Y Leung, K C Allen Chan, Rossa W K Chiu, Y M Dennis Lo. Proc Natl Acad Sci U S A 2020
19
Autonomously replicating episomes contain mdr1 genes in a multidrug-resistant human cell line.
J C Ruiz, K H Choi, D D von Hoff, I B Roninson, G M Wahl. Mol Cell Biol 1989
J C Ruiz, K H Choi, D D von Hoff, I B Roninson, G M Wahl. Mol Cell Biol 1989
19
Extrachromosomal circular DNA is common in yeast.
Henrik D Møller, Lance Parsons, Tue S Jørgensen, David Botstein, Birgitte Regenberg. Proc Natl Acad Sci U S A 2015
Henrik D Møller, Lance Parsons, Tue S Jørgensen, David Botstein, Birgitte Regenberg. Proc Natl Acad Sci U S A 2015
19
Extrachromosomal circular DNA-based amplification and transmission of herbicide resistance in crop weed Amaranthus palmeri.
Dal-Hoe Koo, William T Molin, Christopher A Saski, Jiming Jiang, Karthik Putta, Mithila Jugulam, Bernd Friebe, Bikram S Gill. Proc Natl Acad Sci U S A 2018
Dal-Hoe Koo, William T Molin, Christopher A Saski, Jiming Jiang, Karthik Putta, Mithila Jugulam, Bernd Friebe, Bikram S Gill. Proc Natl Acad Sci U S A 2018
19
Histone-GFP fusion protein enables sensitive analysis of chromosome dynamics in living mammalian cells.
T Kanda, K F Sullivan, G M Wahl. Curr Biol 1998
T Kanda, K F Sullivan, G M Wahl. Curr Biol 1998
19
Selective entrapment of extrachromosomally amplified DNA by nuclear budding and micronucleation during S phase.
N Shimizu, N Itoh, H Utiyama, G M Wahl. J Cell Biol 1998
N Shimizu, N Itoh, H Utiyama, G M Wahl. J Cell Biol 1998
19
EcSeg: Semantic Segmentation of Metaphase Images Containing Extrachromosomal DNA.
Utkrisht Rajkumar, Kristen Turner, Jens Luebeck, Viraj Deshpande, Manmohan Chandraker, Paul Mischel, Vineet Bafna. iScience 2019
Utkrisht Rajkumar, Kristen Turner, Jens Luebeck, Viraj Deshpande, Manmohan Chandraker, Paul Mischel, Vineet Bafna. iScience 2019
41
Massive genomic rearrangement acquired in a single catastrophic event during cancer development.
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19
Gemcitabine eliminates double minute chromosomes from human ovarian cancer cells.
Lisa Yu, Yan Zhao, Chao Quan, Wei Ji, Jing Zhu, Yun Huang, Rongwei Guan, Donglin Sun, Yan Jin, Xiangning Meng,[...]. PLoS One 2013
Lisa Yu, Yan Zhao, Chao Quan, Wei Ji, Jing Zhu, Yun Huang, Rongwei Guan, Donglin Sun, Yan Jin, Xiangning Meng,[...]. PLoS One 2013
19
Structure and evolution of double minutes in diagnosis and relapse brain tumors.
Ke Xu, Liang Ding, Ti-Cheng Chang, Ying Shao, Jason Chiang, Heather Mulder, Shuoguo Wang, Tim I Shaw, Ji Wen, Laura Hover,[...]. Acta Neuropathol 2019
Ke Xu, Liang Ding, Ti-Cheng Chang, Ying Shao, Jason Chiang, Heather Mulder, Shuoguo Wang, Tim I Shaw, Ji Wen, Laura Hover,[...]. Acta Neuropathol 2019
19
Elimination of extrachromosomally amplified MYC genes from human tumor cells reduces their tumorigenicity.
D D Von Hoff, J R McGill, B J Forseth, K K Davidson, T P Bradley, D R Van Devanter, G M Wahl. Proc Natl Acad Sci U S A 1992
D D Von Hoff, J R McGill, B J Forseth, K K Davidson, T P Bradley, D R Van Devanter, G M Wahl. Proc Natl Acad Sci U S A 1992
19
Mitotic segregation of viral and cellular acentric extrachromosomal molecules by chromosome tethering.
T Kanda, M Otter, G M Wahl. J Cell Sci 2001
T Kanda, M Otter, G M Wahl. J Cell Sci 2001
19
Adaptation to diverse nitrogen-limited environments by deletion or extrachromosomal element formation of the GAP1 locus.
David Gresham, Renata Usaite, Susanne Manuela Germann, Michael Lisby, David Botstein, Birgitte Regenberg. Proc Natl Acad Sci U S A 2010
David Gresham, Renata Usaite, Susanne Manuela Germann, Michael Lisby, David Botstein, Birgitte Regenberg. Proc Natl Acad Sci U S A 2010
15
Sensitive detection of circular DNAs at single-nucleotide resolution using guided realignment of partially aligned reads.
Iñigo Prada-Luengo, Anders Krogh, Lasse Maretty, Birgitte Regenberg. BMC Bioinformatics 2019
Iñigo Prada-Luengo, Anders Krogh, Lasse Maretty, Birgitte Regenberg. BMC Bioinformatics 2019
23
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.