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Times Cited: 18
Times Cited: 18
Times Cited
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Similarity
The SWI/SNF chromatin remodeling complex helps resolve R-loop-mediated transcription-replication conflicts.
Aleix Bayona-Feliu, Sonia Barroso, Sergio Muñoz, Andrés Aguilera. Nat Genet 2021
Aleix Bayona-Feliu, Sonia Barroso, Sergio Muñoz, Andrés Aguilera. Nat Genet 2021
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Inhibition of the ATM/Chk2 axis promotes cGAS/STING signaling in ARID1A-deficient tumors.
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PARP inhibition enhances tumor cell-intrinsic immunity in ERCC1-deficient non-small cell lung cancer.
Roman M Chabanon, Gareth Muirhead, Dragomir B Krastev, Julien Adam, Daphné Morel, Marlène Garrido, Andrew Lamb, Clémence Hénon, Nicolas Dorvault, Mathieu Rouanne,[...]. J Clin Invest 2019
Roman M Chabanon, Gareth Muirhead, Dragomir B Krastev, Julien Adam, Daphné Morel, Marlène Garrido, Andrew Lamb, Clémence Hénon, Nicolas Dorvault, Mathieu Rouanne,[...]. J Clin Invest 2019
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R-Loops as Cellular Regulators and Genomic Threats.
Madzia P Crossley, Michael Bocek, Karlene A Cimprich. Mol Cell 2019
Madzia P Crossley, Michael Bocek, Karlene A Cimprich. Mol Cell 2019
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PBRM1 loss defines a nonimmunogenic tumor phenotype associated with checkpoint inhibitor resistance in renal carcinoma.
Xian-De Liu, Wen Kong, Christine B Peterson, Daniel J McGrail, Anh Hoang, Xuesong Zhang, Truong Lam, Patrick G Pilie, Haifeng Zhu, Kathryn E Beckermann,[...]. Nat Commun 2020
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Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer.
Anniina Färkkilä, Doga C Gulhan, Julia Casado, Connor A Jacobson, Huy Nguyen, Bose Kochupurakkal, Zoltan Maliga, Clarence Yapp, Yu-An Chen, Denis Schapiro,[...]. Nat Commun 2020
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ATR kinase inhibitor AZD6738 potentiates CD8+ T cell-dependent antitumor activity following radiation.
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Resolution of R-loops by INO80 promotes DNA replication and maintains cancer cell proliferation and viability.
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Lisa Prendergast, Urszula L McClurg, Rossitsa Hristova, Rolando Berlinguer-Palmini, Sarah Greener, Katie Veitch, Inmaculada Hernandez, Philippe Pasero, Daniel Rico, Jonathan M G Higgins,[...]. Nat Commun 2020
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R-loop formation is a distinctive characteristic of unmethylated human CpG island promoters.
Paul A Ginno, Paul L Lott, Holly C Christensen, Ian Korf, Frédéric Chédin. Mol Cell 2012
Paul A Ginno, Paul L Lott, Holly C Christensen, Ian Korf, Frédéric Chédin. Mol Cell 2012
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Transcription-mediated replication hindrance: a major driver of genome instability.
Belén Gómez-González, Andrés Aguilera. Genes Dev 2019
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R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants.
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Prevalent, Dynamic, and Conserved R-Loop Structures Associate with Specific Epigenomic Signatures in Mammals.
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Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription.
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Transcription-coupled nucleotide excision repair factors promote R-loop-induced genome instability.
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Transcription-Replication Conflict Orientation Modulates R-Loop Levels and Activates Distinct DNA Damage Responses.
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Replication-Transcription Conflicts Generate R-Loops that Orchestrate Bacterial Stress Survival and Pathogenesis.
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The DNA damage response acts as a safeguard against harmful DNA-RNA hybrids of different origins.
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Topoisomerase 1 prevents replication stress at R-loop-enriched transcription termination sites.
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Genomic correlates of response to immune checkpoint therapies in clear cell renal cell carcinoma.
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ATM inhibition enhances cancer immunotherapy by promoting mtDNA leakage and cGAS/STING activation.
Mengjie Hu, Min Zhou, Xuhui Bao, Dong Pan, Meng Jiao, Xinjian Liu, Fang Li, Chuan-Yuan Li. J Clin Invest 2021
Mengjie Hu, Min Zhou, Xuhui Bao, Dong Pan, Meng Jiao, Xinjian Liu, Fang Li, Chuan-Yuan Li. J Clin Invest 2021
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PARP1 inhibitors trigger innate immunity via PARP1 trapping-induced DNA damage response.
Chiho Kim, Xu-Dong Wang, Yonghao Yu. Elife 2020
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Single-Arm Phases 1 and 2 Trial of Niraparib in Combination With Pembrolizumab in Patients With Recurrent Platinum-Resistant Ovarian Carcinoma.
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ATR inhibition potentiates ionizing radiation-induced interferon response via cytosolic nucleic acid-sensing pathways.
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PARP Inhibitor Efficacy Depends on CD8+ T-cell Recruitment via Intratumoral STING Pathway Activation in BRCA-Deficient Models of Triple-Negative Breast Cancer.
Constantia Pantelidou, Olmo Sonzogni, Mateus De Oliveria Taveira, Anita K Mehta, Aditi Kothari, Dan Wang, Tanvi Visal, Michelle K Li, Jocelin Pinto, Jessica A Castrillon,[...]. Cancer Discov 2019
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PARP Inhibition Elicits STING-Dependent Antitumor Immunity in Brca1-Deficient Ovarian Cancer.
Liya Ding, Hye-Jung Kim, Qiwei Wang, Michael Kearns, Tao Jiang, Carolynn E Ohlson, Ben B Li, Shaozhen Xie, Joyce F Liu, Elizabeth H Stover,[...]. Cell Rep 2018
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Open-label Clinical Trial of Niraparib Combined With Pembrolizumab for Treatment of Advanced or Metastatic Triple-Negative Breast Cancer.
Shaveta Vinayak, Sara M Tolaney, Lee Schwartzberg, Monica Mita, Georgia McCann, Antoinette R Tan, Andrea E Wahner-Hendrickson, Andres Forero, Carey Anders, Gerburg M Wulf,[...]. JAMA Oncol 2019
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ATR Inhibition Potentiates the Radiation-induced Inflammatory Tumor Microenvironment.
Magnus T Dillon, Katharina F Bergerhoff, Malin Pedersen, Harriet Whittock, Eva Crespo-Rodriguez, Emmanuel C Patin, Alex Pearson, Henry G Smith, James T E Paget, Radhika R Patel,[...]. Clin Cancer Res 2019
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BRCA2 abrogation triggers innate immune responses potentiated by treatment with PARP inhibitors.
Timo Reisländer, Emilia Puig Lombardi, Florian J Groelly, Ana Miar, Manuela Porru, Serena Di Vito, Benjamin Wright, Helen Lockstone, Annamaria Biroccio, Adrian Harris,[...]. Nat Commun 2019
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Inhibition of ATM Increases Interferon Signaling and Sensitizes Pancreatic Cancer to Immune Checkpoint Blockade Therapy.
Qiang Zhang, Michael D Green, Xueting Lang, Jenny Lazarus, Joshua D Parsels, Shuang Wei, Leslie A Parsels, Jiaqi Shi, Nithya Ramnath, Daniel R Wahl,[...]. Cancer Res 2019
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ARID1A regulates R-loop associated DNA replication stress.
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Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma.
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The Many Roles of BAF (mSWI/SNF) and PBAF Complexes in Cancer.
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Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy.
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A major chromatin regulator determines resistance of tumor cells to T cell-mediated killing.
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Targeting DNA Damage Response Promotes Antitumor Immunity through STING-Mediated T-cell Activation in Small Cell Lung Cancer.
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ATR inhibitor AZD6738 enhances the antitumor activity of radiotherapy and immune checkpoint inhibitors by potentiating the tumor immune microenvironment in hepatocellular carcinoma.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.