Yaowaluck Hongkaew, Wendy Y Wang, Roger Gaedigk, Chonlaphat Sukasem, Andrea Gaedigk. Pharmacogenomics 2021
Times Cited: 4
Times Cited: 4
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The Pharmacogene Variation (PharmVar) Consortium: Incorporation of the Human Cytochrome P450 (CYP) Allele Nomenclature Database.
Andrea Gaedigk, Magnus Ingelman-Sundberg, Neil A Miller, J Steven Leeder, Michelle Whirl-Carrillo, Teri E Klein. Clin Pharmacol Ther 2018
Andrea Gaedigk, Magnus Ingelman-Sundberg, Neil A Miller, J Steven Leeder, Michelle Whirl-Carrillo, Teri E Klein. Clin Pharmacol Ther 2018
75
Stargazer: a software tool for calling star alleles from next-generation sequencing data using CYP2D6 as a model.
Seung-Been Lee, Marsha M Wheeler, Karynne Patterson, Sean McGee, Rachel Dalton, Erica L Woodahl, Andrea Gaedigk, Kenneth E Thummel, Deborah A Nickerson. Genet Med 2019
Seung-Been Lee, Marsha M Wheeler, Karynne Patterson, Sean McGee, Rachel Dalton, Erica L Woodahl, Andrea Gaedigk, Kenneth E Thummel, Deborah A Nickerson. Genet Med 2019
50
Physicochemical Properties, Biotransformation, and Transport Pathways of Established and Newly Approved Medications: A Systematic Review of the Top 200 Most Prescribed Drugs vs. the FDA-Approved Drugs Between 2005 and 2016.
Anitha Saravanakumar, Armin Sadighi, Rachel Ryu, Fatemeh Akhlaghi. Clin Pharmacokinet 2019
Anitha Saravanakumar, Armin Sadighi, Rachel Ryu, Fatemeh Akhlaghi. Clin Pharmacokinet 2019
50
Clinical pharmacogenetics implementation consortium guideline (CPIC) for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants: 2016 update.
J K Hicks, K Sangkuhl, J J Swen, V L Ellingrod, D J Müller, K Shimoda, J R Bishop, E D Kharasch, T C Skaar, A Gaedigk,[...]. Clin Pharmacol Ther 2017
J K Hicks, K Sangkuhl, J J Swen, V L Ellingrod, D J Müller, K Shimoda, J R Bishop, E D Kharasch, T C Skaar, A Gaedigk,[...]. Clin Pharmacol Ther 2017
50
Constellation: a tool for rapid, automated phenotype assignment of a highly polymorphic pharmacogene, CYP2D6, from whole-genome sequences.
Greyson P Twist, Andrea Gaedigk, Neil A Miller, Emily G Farrow, Laurel K Willig, Darrell L Dinwiddie, Josh E Petrikin, Sarah E Soden, Suzanne Herd, Margaret Gibson,[...]. NPJ Genom Med 2016
Greyson P Twist, Andrea Gaedigk, Neil A Miller, Emily G Farrow, Laurel K Willig, Darrell L Dinwiddie, Josh E Petrikin, Sarah E Soden, Suzanne Herd, Margaret Gibson,[...]. NPJ Genom Med 2016
50
CYP2D6, SULT1A1 and UGT2B17 copy number variation: quantitative detection by multiplex PCR.
Andrea Gaedigk, Greyson P Twist, J Steven Leeder. Pharmacogenomics 2012
Andrea Gaedigk, Greyson P Twist, J Steven Leeder. Pharmacogenomics 2012
50
A systematic comparison of pharmacogene star allele calling bioinformatics algorithms: a focus on CYP2D6 genotyping.
David Twesigomwe, Galen E B Wright, Britt I Drögemöller, Jorge da Rocha, Zané Lombard, Scott Hazelhurst. NPJ Genom Med 2020
David Twesigomwe, Galen E B Wright, Britt I Drögemöller, Jorge da Rocha, Zané Lombard, Scott Hazelhurst. NPJ Genom Med 2020
50
Characterization of Reference Materials for Genetic Testing of CYP2D6 Alleles: A GeT-RM Collaborative Project.
Andrea Gaedigk, Amy Turner, Robin E Everts, Stuart A Scott, Praful Aggarwal, Ulrich Broeckel, Gwendolyn A McMillin, Roberta Melis, Erin C Boone, Victoria M Pratt,[...]. J Mol Diagn 2019
Andrea Gaedigk, Amy Turner, Robin E Everts, Stuart A Scott, Praful Aggarwal, Ulrich Broeckel, Gwendolyn A McMillin, Roberta Melis, Erin C Boone, Victoria M Pratt,[...]. J Mol Diagn 2019
50
Cytochrome P4502D6 (CYP2D6) gene locus heterogeneity: characterization of gene duplication events.
A Gaedigk, L Ndjountché, K Divakaran, L Dianne Bradford, I Zineh, T F Oberlander, D C Brousseau, D G McCarver, J A Johnson, S W Alander,[...]. Clin Pharmacol Ther 2007
A Gaedigk, L Ndjountché, K Divakaran, L Dianne Bradford, I Zineh, T F Oberlander, D C Brousseau, D G McCarver, J A Johnson, S W Alander,[...]. Clin Pharmacol Ther 2007
50
Toward predicting CYP2D6-mediated variable drug response from CYP2D6 gene sequencing data.
Maaike van der Lee, William G Allard, Rolf H A M Vossen, Renée F Baak-Pablo, Roberta Menafra, Birgit A L M Deiman, Maarten J Deenen, Patrick Neven, Inger Johansson, Stefano Gastaldello,[...]. Sci Transl Med 2021
Maaike van der Lee, William G Allard, Rolf H A M Vossen, Renée F Baak-Pablo, Roberta Menafra, Birgit A L M Deiman, Maarten J Deenen, Patrick Neven, Inger Johansson, Stefano Gastaldello,[...]. Sci Transl Med 2021
50
Identification of Novel CYP2D7-2D6 Hybrids: Non-Functional and Functional Variants.
Andrea Gaedigk, Lazara Karelia Montane Jaime, Joseph S Bertino, Anick Bérard, Victoria M Pratt, L Dianne Bradfordand, J Steven Leeder. Front Pharmacol 2010
Andrea Gaedigk, Lazara Karelia Montane Jaime, Joseph S Bertino, Anick Bérard, Victoria M Pratt, L Dianne Bradfordand, J Steven Leeder. Front Pharmacol 2010
50
Cyrius: accurate CYP2D6 genotyping using whole-genome sequencing data.
Xiao Chen, Fei Shen, Nina Gonzaludo, Alka Malhotra, Cande Rogert, Ryan J Taft, David R Bentley, Michael A Eberle. Pharmacogenomics J 2021
Xiao Chen, Fei Shen, Nina Gonzaludo, Alka Malhotra, Cande Rogert, Ryan J Taft, David R Bentley, Michael A Eberle. Pharmacogenomics J 2021
50
Clinical Pharmacogenetics Implementation Consortium guideline for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants.
J K Hicks, J J Swen, C F Thorn, K Sangkuhl, E D Kharasch, V L Ellingrod, T C Skaar, D J Müller, A Gaedigk, J C Stingl. Clin Pharmacol Ther 2013
J K Hicks, J J Swen, C F Thorn, K Sangkuhl, E D Kharasch, V L Ellingrod, T C Skaar, D J Müller, A Gaedigk, J C Stingl. Clin Pharmacol Ther 2013
50
PharmVar GeneFocus: CYP2D6.
Charity Nofziger, Amy J Turner, Katrin Sangkuhl, Michelle Whirl-Carrillo, José A G Agúndez, John L Black, Henry M Dunnenberger, Gualberto Ruano, Martin A Kennedy, Michael S Phillips,[...]. Clin Pharmacol Ther 2020
Charity Nofziger, Amy J Turner, Katrin Sangkuhl, Michelle Whirl-Carrillo, José A G Agúndez, John L Black, Henry M Dunnenberger, Gualberto Ruano, Martin A Kennedy, Michael S Phillips,[...]. Clin Pharmacol Ther 2020
50
CYP2D6 Haplotype Determination Using Long Range Allele-Specific Amplification: Resolution of a Complex Genotype and a Discordant Genotype Involving the CYP2D6*59 Allele.
Andrea Gaedigk, Amanda K Riffel, J Steven Leeder. J Mol Diagn 2015
Andrea Gaedigk, Amanda K Riffel, J Steven Leeder. J Mol Diagn 2015
50
Standardizing CYP2D6 Genotype to Phenotype Translation: Consensus Recommendations from the Clinical Pharmacogenetics Implementation Consortium and Dutch Pharmacogenetics Working Group.
Kelly E Caudle, Katrin Sangkuhl, Michelle Whirl-Carrillo, Jesse J Swen, Cyrine E Haidar, Teri E Klein, Roseann S Gammal, Mary V Relling, Stuart A Scott, Daniel L Hertz,[...]. Clin Transl Sci 2020
Kelly E Caudle, Katrin Sangkuhl, Michelle Whirl-Carrillo, Jesse J Swen, Cyrine E Haidar, Teri E Klein, Roseann S Gammal, Mary V Relling, Stuart A Scott, Daniel L Hertz,[...]. Clin Transl Sci 2020
50
Sequencing the CYP2D6 gene: from variant allele discovery to clinical pharmacogenetic testing.
Yao Yang, Mariana R Botton, Erick R Scott, Stuart A Scott. Pharmacogenomics 2017
Yao Yang, Mariana R Botton, Erick R Scott, Stuart A Scott. Pharmacogenomics 2017
50
Clinical Pharmacogenetics Implementation Consortium guidelines for cytochrome P450 2D6 genotype and codeine therapy: 2014 update.
K R Crews, A Gaedigk, H M Dunnenberger, J S Leeder, T E Klein, K E Caudle, C E Haidar, D D Shen, J T Callaghan, S Sadhasivam,[...]. Clin Pharmacol Ther 2014
K R Crews, A Gaedigk, H M Dunnenberger, J S Leeder, T E Klein, K E Caudle, C E Haidar, D D Shen, J T Callaghan, S Sadhasivam,[...]. Clin Pharmacol Ther 2014
50
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors.
J K Hicks, J R Bishop, K Sangkuhl, D J Müller, Y Ji, S G Leckband, J S Leeder, R L Graham, D L Chiulli, A LLerena,[...]. Clin Pharmacol Ther 2015
J K Hicks, J R Bishop, K Sangkuhl, D J Müller, Y Ji, S G Leckband, J S Leeder, R L Graham, D L Chiulli, A LLerena,[...]. Clin Pharmacol Ther 2015
50
Validation of a multi-gene qPCR-based pharmacogenomics panel across major ethnic groups in Singapore and Indonesia.
Anar Sanjaykumar Kothary, Caroline Mahendra, Mingchen Tan, Eunice Jia Min Tan, Jacelyn Phua Hong Yi, Gabriella, Tan Xin Hui Jocelyn, Jessline Stephanie Haruman, Zhihao Tan, Chun Kiat Lee,[...]. Pharmacogenomics 2021
Anar Sanjaykumar Kothary, Caroline Mahendra, Mingchen Tan, Eunice Jia Min Tan, Jacelyn Phua Hong Yi, Gabriella, Tan Xin Hui Jocelyn, Jessline Stephanie Haruman, Zhihao Tan, Chun Kiat Lee,[...]. Pharmacogenomics 2021
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Characterization of (+/-)-bufuralol hydroxylation activities in liver microsomes of Japanese and Caucasian subjects genotyped for CYP2D6.
T Shimada, F Tsumura, H Yamazaki, F P Guengerich, K Inoue. Pharmacogenetics 2001
T Shimada, F Tsumura, H Yamazaki, F P Guengerich, K Inoue. Pharmacogenetics 2001
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In vivo characterization of CYP2D6*12, *29 and *84 using dextromethorphan as a probe drug: a case report.
Andrea Gaedigk, Greyson P Twist, Emily G Farrow, Jennifer A Lowry, Sarah E Soden, Neil A Miller. Pharmacogenomics 2017
Andrea Gaedigk, Greyson P Twist, Emily G Farrow, Jennifer A Lowry, Sarah E Soden, Neil A Miller. Pharmacogenomics 2017
25
Characterization and PCR-based detection of two different hybrid CYP2D7P/CYP2D6 alleles associated with the poor metabolizer phenotype.
A K Daly, K S Fairbrother, O A Andreassen, S J London, J R Idle, V M Steen. Pharmacogenetics 1996
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Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants.
David R Nelson, Darryl C Zeldin, Susan M G Hoffman, Lois J Maltais, Hester M Wain, Daniel W Nebert. Pharmacogenetics 2004
David R Nelson, Darryl C Zeldin, Susan M G Hoffman, Lois J Maltais, Hester M Wain, Daniel W Nebert. Pharmacogenetics 2004
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CYP2D6: novel genomic structures and alleles.
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Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: Meta-analysis of data from genome-wide association studies.
Chiara Fabbri, Katherine E Tansey, Roy H Perlis, Joanna Hauser, Neven Henigsberg, Wolfgang Maier, Ole Mors, Anna Placentino, Marcella Rietschel, Daniel Souery,[...]. Eur Neuropsychopharmacol 2018
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Nanopore sequencing of the pharmacogene CYP2D6 allows simultaneous haplotyping and detection of duplications.
Yusmiati Liau, Simran Maggo, Allison L Miller, John F Pearson, Martin A Kennedy, Simone L Cree. Pharmacogenomics 2019
Yusmiati Liau, Simran Maggo, Allison L Miller, John F Pearson, Martin A Kennedy, Simone L Cree. Pharmacogenomics 2019
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Failure to respond to treatment with typical antipsychotics is not associated with CYP2D6 ultrarapid hydroxylation.
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An efficient strategy for detection of known and new mutations of the CYP2D6 gene using single strand conformation polymorphism analysis.
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PharmVar GeneFocus: CYP2C19.
Mariana R Botton, Michelle Whirl-Carrillo, Andria L Del Tredici, Katrin Sangkuhl, Larisa H Cavallari, José A G Agúndez, Jorge Duconge, Ming Ta Michael Lee, Erica L Woodahl, Karla Claudio-Campos,[...]. Clin Pharmacol Ther 2021
Mariana R Botton, Michelle Whirl-Carrillo, Andria L Del Tredici, Katrin Sangkuhl, Larisa H Cavallari, José A G Agúndez, Jorge Duconge, Ming Ta Michael Lee, Erica L Woodahl, Karla Claudio-Campos,[...]. Clin Pharmacol Ther 2021
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An additional allelic variant of the CYP2D6 gene causing impaired metabolism of sparteine.
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Identification of a novel non-functional CYP2D6 allele, CYP2D6*69, in a Caucasian poor metabolizer individual.
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How Can Drug Metabolism and Transporter Genetics Inform Psychotropic Prescribing?
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The human debrisoquine 4-hydroxylase (CYP2D) locus: sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene.
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Long-Read Single Molecule Real-Time Full Gene Sequencing of Cytochrome P450-2D6.
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CYP2D7-2D6 hybrid tandems: identification of novel CYP2D6 duplication arrangements and implications for phenotype prediction.
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Structural variation at the CYP2C locus: Characterization of deletion and duplication alleles.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.