Yitian Zhou, Volker M Lauschke. Clin Pharmacol Ther 2021
Times Cited: 10
Times Cited: 10
Times Cited
Times Co-cited
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Computational Methods for the Pharmacogenetic Interpretation of Next Generation Sequencing Data.
Yitian Zhou, Kohei Fujikura, Souren Mkrtchian, Volker M Lauschke. Front Pharmacol 2018
Yitian Zhou, Kohei Fujikura, Souren Mkrtchian, Volker M Lauschke. Front Pharmacol 2018
60
Integrating rare genetic variants into pharmacogenetic drug response predictions.
Magnus Ingelman-Sundberg, Souren Mkrtchian, Yitian Zhou, Volker M Lauschke. Hum Genomics 2018
Magnus Ingelman-Sundberg, Souren Mkrtchian, Yitian Zhou, Volker M Lauschke. Hum Genomics 2018
60
Rare genetic variants in cellular transporters, metabolic enzymes, and nuclear receptors can be important determinants of interindividual differences in drug response.
Mikael Kozyra, Magnus Ingelman-Sundberg, Volker M Lauschke. Genet Med 2017
Mikael Kozyra, Magnus Ingelman-Sundberg, Volker M Lauschke. Genet Med 2017
60
An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people.
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Matthew R Nelson, Daniel Wegmann, Margaret G Ehm, Darren Kessner, Pamela St Jean, Claudio Verzilli, Judong Shen, Zhengzheng Tang, Silviu-Alin Bacanu, Dana Fraser,[...]. Science 2012
50
Ethnogeographic and inter-individual variability of human ABC transporters.
Qingyang Xiao, Yitian Zhou, Volker M Lauschke. Hum Genet 2020
Qingyang Xiao, Yitian Zhou, Volker M Lauschke. Hum Genet 2020
50
Heritability of metoprolol and torsemide pharmacokinetics.
J Matthaei, J Brockmöller, M V Tzvetkov, D Sehrt, C Sachse-Seeboth, J B Hjelmborg, S Möller, U Halekoh, U Hofmann, M Schwab,[...]. Clin Pharmacol Ther 2015
J Matthaei, J Brockmöller, M V Tzvetkov, D Sehrt, C Sachse-Seeboth, J B Hjelmborg, S Möller, U Halekoh, U Hofmann, M Schwab,[...]. Clin Pharmacol Ther 2015
50
Population-scale predictions of DPD and TPMT phenotypes using a quantitative pharmacogene-specific ensemble classifier.
Yitian Zhou, Carolina Dagli Hernandez, Volker M Lauschke. Br J Cancer 2020
Yitian Zhou, Carolina Dagli Hernandez, Volker M Lauschke. Br J Cancer 2020
50
An optimized prediction framework to assess the functional impact of pharmacogenetic variants.
Yitian Zhou, Souren Mkrtchian, Masaki Kumondai, Masahiro Hiratsuka, Volker M Lauschke. Pharmacogenomics J 2019
Yitian Zhou, Souren Mkrtchian, Masaki Kumondai, Masahiro Hiratsuka, Volker M Lauschke. Pharmacogenomics J 2019
50
Pharmacogenomics of GPCR Drug Targets.
Alexander S Hauser, Sreenivas Chavali, Ikuo Masuho, Leonie J Jahn, Kirill A Martemyanov, David E Gloriam, M Madan Babu. Cell 2018
Alexander S Hauser, Sreenivas Chavali, Ikuo Masuho, Leonie J Jahn, Kirill A Martemyanov, David E Gloriam, M Madan Babu. Cell 2018
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Emerging strategies to bridge the gap between pharmacogenomic research and its clinical implementation.
Volker M Lauschke, Magnus Ingelman-Sundberg. NPJ Genom Med 2020
Volker M Lauschke, Magnus Ingelman-Sundberg. NPJ Genom Med 2020
40
Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation.
Ulrich M Zanger, Matthias Schwab. Pharmacol Ther 2013
Ulrich M Zanger, Matthias Schwab. Pharmacol Ther 2013
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Genetic variation in human drug-related genes.
Charlotta Pauline Irmgard Schärfe, Roman Tremmel, Matthias Schwab, Oliver Kohlbacher, Debora Susan Marks. Genome Med 2017
Charlotta Pauline Irmgard Schärfe, Roman Tremmel, Matthias Schwab, Oliver Kohlbacher, Debora Susan Marks. Genome Med 2017
40
The genetic landscape of the human solute carrier (SLC) transporter superfamily.
Lena Schaller, Volker M Lauschke. Hum Genet 2019
Lena Schaller, Volker M Lauschke. Hum Genet 2019
40
Genetic variability and population diversity of the human SLCO (OATP) transporter family.
Boyao Zhang, Volker M Lauschke. Pharmacol Res 2019
Boyao Zhang, Volker M Lauschke. Pharmacol Res 2019
40
Rare genetic variability in human drug target genes modulates drug response and can guide precision medicine.
Yitian Zhou, Gabriel Herras Arribas, Ainoleena Turku, Tuuli Jürgenson, Souren Mkrtchian, Kristi Krebs, Yi Wang, Barbora Svobodova, Lili Milani, Gunnar Schulte,[...]. Sci Adv 2021
Yitian Zhou, Gabriel Herras Arribas, Ainoleena Turku, Tuuli Jürgenson, Souren Mkrtchian, Kristi Krebs, Yi Wang, Barbora Svobodova, Lili Milani, Gunnar Schulte,[...]. Sci Adv 2021
50
Worldwide Distribution of Cytochrome P450 Alleles: A Meta-analysis of Population-scale Sequencing Projects.
Y Zhou, M Ingelman-Sundberg, V M Lauschke. Clin Pharmacol Ther 2017
Y Zhou, M Ingelman-Sundberg, V M Lauschke. Clin Pharmacol Ther 2017
40
Gene-Specific Variant Classifier (DPYD-Varifier) to Identify Deleterious Alleles of Dihydropyrimidine Dehydrogenase.
Shikshya Shrestha, Cheng Zhang, Calvin R Jerde, Qian Nie, Hu Li, Steven M Offer, Robert B Diasio. Clin Pharmacol Ther 2018
Shikshya Shrestha, Cheng Zhang, Calvin R Jerde, Qian Nie, Hu Li, Steven M Offer, Robert B Diasio. Clin Pharmacol Ther 2018
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The mutational constraint spectrum quantified from variation in 141,456 humans.
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30
A method and server for predicting damaging missense mutations.
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A novel machine learning-based approach for the computational functional assessment of pharmacogenomic variants.
Maria-Theodora Pandi, Maria Koromina, Iordanis Tsafaridis, Sotirios Patsilinakos, Evangelos Christoforou, Peter J van der Spek, George P Patrinos. Hum Genomics 2021
Maria-Theodora Pandi, Maria Koromina, Iordanis Tsafaridis, Sotirios Patsilinakos, Evangelos Christoforou, Peter J van der Spek, George P Patrinos. Hum Genomics 2021
50
The Pharmacogene Variation (PharmVar) Consortium: Incorporation of the Human Cytochrome P450 (CYP) Allele Nomenclature Database.
Andrea Gaedigk, Magnus Ingelman-Sundberg, Neil A Miller, J Steven Leeder, Michelle Whirl-Carrillo, Teri E Klein. Clin Pharmacol Ther 2018
Andrea Gaedigk, Magnus Ingelman-Sundberg, Neil A Miller, J Steven Leeder, Michelle Whirl-Carrillo, Teri E Klein. Clin Pharmacol Ther 2018
30
Genetic variation in the human cytochrome P450 supergene family.
Kohei Fujikura, Magnus Ingelman-Sundberg, Volker M Lauschke. Pharmacogenet Genomics 2015
Kohei Fujikura, Magnus Ingelman-Sundberg, Volker M Lauschke. Pharmacogenet Genomics 2015
30
The global spectrum of protein-coding pharmacogenomic diversity.
G E B Wright, B Carleton, M R Hayden, C J D Ross. Pharmacogenomics J 2018
G E B Wright, B Carleton, M R Hayden, C J D Ross. Pharmacogenomics J 2018
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Pharmacogenomic Biomarkers for Improved Drug Therapy-Recent Progress and Future Developments.
Volker M Lauschke, Lili Milani, Magnus Ingelman-Sundberg. AAPS J 2017
Volker M Lauschke, Lili Milani, Magnus Ingelman-Sundberg. AAPS J 2017
30
Long-read human genome sequencing and its applications.
Glennis A Logsdon, Mitchell R Vollger, Evan E Eichler. Nat Rev Genet 2020
Glennis A Logsdon, Mitchell R Vollger, Evan E Eichler. Nat Rev Genet 2020
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Prediction of drug response and adverse drug reactions: From twin studies to Next Generation Sequencing.
Volker M Lauschke, Magnus Ingelman-Sundberg. Eur J Pharm Sci 2019
Volker M Lauschke, Magnus Ingelman-Sundberg. Eur J Pharm Sci 2019
30
Translating genotype data of 44,000 biobank participants into clinical pharmacogenetic recommendations: challenges and solutions.
Sulev Reisberg, Kristi Krebs, Maarja Lepamets, Mart Kals, Reedik Mägi, Kristjan Metsalu, Volker M Lauschke, Jaak Vilo, Lili Milani. Genet Med 2019
Sulev Reisberg, Kristi Krebs, Maarja Lepamets, Mart Kals, Reedik Mägi, Kristjan Metsalu, Volker M Lauschke, Jaak Vilo, Lili Milani. Genet Med 2019
20
Germline variant burden in multidrug resistance transporters is a therapy-specific predictor of survival in breast cancer patients.
Qingyang Xiao, Yitian Zhou, Stefan Winter, Florian Büttner, Elke Schaeffeler, Matthias Schwab, Volker M Lauschke. Int J Cancer 2020
Qingyang Xiao, Yitian Zhou, Stefan Winter, Florian Büttner, Elke Schaeffeler, Matthias Schwab, Volker M Lauschke. Int J Cancer 2020
20
Towards precision medicine: advances in computational approaches for the analysis of human variants.
Thomas A Peterson, Emily Doughty, Maricel G Kann. J Mol Biol 2013
Thomas A Peterson, Emily Doughty, Maricel G Kann. J Mol Biol 2013
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Analysis of protein-coding genetic variation in 60,706 humans.
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20
A model-based cost-effectiveness analysis of pharmacogenomic panel testing in cardiovascular disease management: preemptive, reactive, or none?
Ye Zhu, James P Moriarty, Kristi M Swanson, Paul Y Takahashi, Suzette J Bielinski, Richard Weinshilboum, Liewei Wang, Bijan J Borah. Genet Med 2021
Ye Zhu, James P Moriarty, Kristi M Swanson, Paul Y Takahashi, Suzette J Bielinski, Richard Weinshilboum, Liewei Wang, Bijan J Borah. Genet Med 2021
20
Unveiling the guidance heterogeneity for genome-informed drug treatment interventions among regulatory bodies and research consortia.
Stefania Koutsilieri, Foteini Tzioufa, Despoina-Christina Sismanoglou, George P Patrinos. Pharmacol Res 2020
Stefania Koutsilieri, Foteini Tzioufa, Despoina-Christina Sismanoglou, George P Patrinos. Pharmacol Res 2020
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CADD-Splice-improving genome-wide variant effect prediction using deep learning-derived splice scores.
Philipp Rentzsch, Max Schubach, Jay Shendure, Martin Kircher. Genome Med 2021
Philipp Rentzsch, Max Schubach, Jay Shendure, Martin Kircher. Genome Med 2021
20
Pharmacogenomic Next-Generation DNA Sequencing: Lessons from the Identification and Functional Characterization of Variants of Unknown Significance in CYP2C9 and CYP2C19.
Sandhya Devarajan, Irene Moon, Ming-Fen Ho, Nicholas B Larson, Drew R Neavin, Ann M Moyer, John L Black, Suzette J Bielinski, Steven E Scherer, Liewei Wang,[...]. Drug Metab Dispos 2019
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A spectral approach integrating functional genomic annotations for coding and noncoding variants.
Iuliana Ionita-Laza, Kenneth McCallum, Bin Xu, Joseph D Buxbaum. Nat Genet 2016
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The Clinical Pharmacogenetics Implementation Consortium: 10 Years Later.
Mary V Relling, Teri E Klein, Roseann S Gammal, Michelle Whirl-Carrillo, James M Hoffman, Kelly E Caudle. Clin Pharmacol Ther 2020
Mary V Relling, Teri E Klein, Roseann S Gammal, Michelle Whirl-Carrillo, James M Hoffman, Kelly E Caudle. Clin Pharmacol Ther 2020
20
Pharmacogenetics Guidelines: Overview and Comparison of the DPWG, CPIC, CPNDS, and RNPGx Guidelines.
Heshu Abdullah-Koolmees, Antonius M van Keulen, Marga Nijenhuis, Vera H M Deneer. Front Pharmacol 2021
Heshu Abdullah-Koolmees, Antonius M van Keulen, Marga Nijenhuis, Vera H M Deneer. Front Pharmacol 2021
20
Pharmacogenetic allele nomenclature: International workgroup recommendations for test result reporting.
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20
PharmVar GeneFocus: CYP2B6.
Zeruesenay Desta, Ahmed El-Boraie, Li Gong, Andrew A Somogyi, Volker M Lauschke, Collet Dandara, Kathrin Klein, Neil A Miller, Teri E Klein, Rachel F Tyndale,[...]. Clin Pharmacol Ther 2021
Zeruesenay Desta, Ahmed El-Boraie, Li Gong, Andrew A Somogyi, Volker M Lauschke, Collet Dandara, Kathrin Klein, Neil A Miller, Teri E Klein, Rachel F Tyndale,[...]. Clin Pharmacol Ther 2021
20
Cyrius: accurate CYP2D6 genotyping using whole-genome sequencing data.
Xiao Chen, Fei Shen, Nina Gonzaludo, Alka Malhotra, Cande Rogert, Ryan J Taft, David R Bentley, Michael A Eberle. Pharmacogenomics J 2021
Xiao Chen, Fei Shen, Nina Gonzaludo, Alka Malhotra, Cande Rogert, Ryan J Taft, David R Bentley, Michael A Eberle. Pharmacogenomics J 2021
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PharmVar GeneFocus: CYP2D6.
Charity Nofziger, Amy J Turner, Katrin Sangkuhl, Michelle Whirl-Carrillo, José A G Agúndez, John L Black, Henry M Dunnenberger, Gualberto Ruano, Martin A Kennedy, Michael S Phillips,[...]. Clin Pharmacol Ther 2020
Charity Nofziger, Amy J Turner, Katrin Sangkuhl, Michelle Whirl-Carrillo, José A G Agúndez, John L Black, Henry M Dunnenberger, Gualberto Ruano, Martin A Kennedy, Michael S Phillips,[...]. Clin Pharmacol Ther 2020
20
Allelic decomposition and exact genotyping of highly polymorphic and structurally variant genes.
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DNA sequencing at 40: past, present and future.
Jay Shendure, Shankar Balasubramanian, George M Church, Walter Gilbert, Jane Rogers, Jeffery A Schloss, Robert H Waterston. Nature 2017
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Towards population-scale long-read sequencing.
Wouter De Coster, Matthias H Weissensteiner, Fritz J Sedlazeck. Nat Rev Genet 2021
Wouter De Coster, Matthias H Weissensteiner, Fritz J Sedlazeck. Nat Rev Genet 2021
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The evaluation of tools used to predict the impact of missense variants is hindered by two types of circularity.
Dominik G Grimm, Chloé-Agathe Azencott, Fabian Aicheler, Udo Gieraths, Daniel G MacArthur, Kaitlin E Samocha, David N Cooper, Peter D Stenson, Mark J Daly, Jordan W Smoller,[...]. Hum Mutat 2015
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The ethnogeographic variability of genetic factors underlying G6PD deficiency.
Maria Koromina, Maria Theodora Pandi, Peter J van der Spek, George P Patrinos, Volker M Lauschke. Pharmacol Res 2021
Maria Koromina, Maria Theodora Pandi, Peter J van der Spek, George P Patrinos, Volker M Lauschke. Pharmacol Res 2021
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Cost-effectiveness of pharmacogenetic-guided treatment: are we there yet?
M Verbelen, M E Weale, C M Lewis. Pharmacogenomics J 2017
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Requirements for comprehensive pharmacogenetic genotyping platforms.
Volker M Lauschke, Magnus Ingelman-Sundberg. Pharmacogenomics 2016
Volker M Lauschke, Magnus Ingelman-Sundberg. Pharmacogenomics 2016
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CYP2C9 and CYP2C19: Deep Mutational Scanning and Functional Characterization of Genomic Missense Variants.
Lingxin Zhang, Vivekananda Sarangi, Irene Moon, Jia Yu, Duan Liu, Sandhya Devarajan, Joel M Reid, Krishna R Kalari, Liewei Wang, Richard Weinshilboum. Clin Transl Sci 2020
Lingxin Zhang, Vivekananda Sarangi, Irene Moon, Jia Yu, Duan Liu, Sandhya Devarajan, Joel M Reid, Krishna R Kalari, Liewei Wang, Richard Weinshilboum. Clin Transl Sci 2020
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Massively parallel characterization of CYP2C9 variant enzyme activity and abundance.
Clara J Amorosi, Melissa A Chiasson, Matthew G McDonald, Lai Hong Wong, Katherine A Sitko, Gabriel Boyle, John P Kowalski, Allan E Rettie, Douglas M Fowler, Maitreya J Dunham. Am J Hum Genet 2021
Clara J Amorosi, Melissa A Chiasson, Matthew G McDonald, Lai Hong Wong, Katherine A Sitko, Gabriel Boyle, John P Kowalski, Allan E Rettie, Douglas M Fowler, Maitreya J Dunham. Am J Hum Genet 2021
20
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.