A citation-based method for searching scientific literature

Madeleine Bossaert, Angélique Pipier, Jean-Francois Riou, Céline Noirot, Linh-Trang Nguyên, Remy-Felix Serre, Olivier Bouchez, Eric Defrancq, Patrick Calsou, Sébastien Britton, Dennis Gomez. Elife 2021
Times Cited: 15







List of co-cited articles
175 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours.
Hong Xu, Marco Di Antonio, Steven McKinney, Veena Mathew, Brandon Ho, Nigel J O'Neil, Nancy Dos Santos, Jennifer Silvester, Vivien Wei, Jessica Garcia,[...]. Nat Commun 2017
246
66

The primary mechanism of cytotoxicity of the chemotherapeutic agent CX-5461 is topoisomerase II poisoning.
Peter M Bruno, Mengrou Lu, Kady A Dennis, Haider Inam, Connor J Moore, John Sheehe, Stephen J Elledge, Michael T Hemann, Justin R Pritchard. Proc Natl Acad Sci U S A 2020
49
60

A Genetic Map of the Response to DNA Damage in Human Cells.
Michele Olivieri, Tiffany Cho, Alejandro Álvarez-Quilón, Kejiao Li, Matthew J Schellenberg, Michal Zimmermann, Nicole Hustedt, Silvia Emma Rossi, Salomé Adam, Henrique Melo,[...]. Cell 2020
131
46

First-in-Human RNA Polymerase I Transcription Inhibitor CX-5461 in Patients with Advanced Hematologic Cancers: Results of a Phase I Dose-Escalation Study.
Amit Khot, Natalie Brajanovski, Donald P Cameron, Nadine Hein, Kylee H Maclachlan, Elaine Sanij, John Lim, John Soong, Emma Link, Piers Blombery,[...]. Cancer Discov 2019
70
40

Discovery of CX-5461, the First Direct and Selective Inhibitor of RNA Polymerase I, for Cancer Therapeutics.
Mustapha Haddach, Michael K Schwaebe, Jerome Michaux, Johnny Nagasawa, Sean E O'Brien, Jeffrey P Whitten, Fabrice Pierre, Pauline Kerdoncuff, Levan Darjania, Ryan Stansfield,[...]. ACS Med Chem Lett 2012
71
40

CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer.
Elaine Sanij, Katherine M Hannan, Jiachen Xuan, Shunfei Yan, Jessica E Ahern, Anna S Trigos, Natalie Brajanovski, Jinbae Son, Keefe T Chan, Olga Kondrashova,[...]. Nat Commun 2020
51
33

Targeting RNA polymerase I with an oral small molecule CX-5461 inhibits ribosomal RNA synthesis and solid tumor growth.
Denis Drygin, Amy Lin, Josh Bliesath, Caroline B Ho, Sean E O'Brien, Chris Proffitt, Mayuko Omori, Mustapha Haddach, Michael K Schwaebe, Adam Siddiqui-Jain,[...]. Cancer Res 2011
348
33

DNA double-strand break repair-pathway choice in somatic mammalian cells.
Ralph Scully, Arvind Panday, Rajula Elango, Nicholas A Willis. Nat Rev Mol Cell Biol 2019
401
26

DNA damage and genome instability by G-quadruplex ligands are mediated by R loops in human cancer cells.
Alessio De Magis, Stefano G Manzo, Marco Russo, Jessica Marinello, Rita Morigi, Olivier Sordet, Giovanni Capranico. Proc Natl Acad Sci U S A 2019
120
26

Roles of eukaryotic topoisomerases in transcription, replication and genomic stability.
Yves Pommier, Yilun Sun, Shar-Yin N Huang, John L Nitiss. Nat Rev Mol Cell Biol 2016
436
26



Anticancer activity of CX-3543: a direct inhibitor of rRNA biogenesis.
Denis Drygin, Adam Siddiqui-Jain, Sean O'Brien, Michael Schwaebe, Amy Lin, Josh Bliesath, Caroline B Ho, Chris Proffitt, Katy Trent, Jeffrey P Whitten,[...]. Cancer Res 2009
351
26

Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription.
Sandie Tuduri, Laure Crabbé, Chiara Conti, Hélène Tourrière, Heidi Holtgreve-Grez, Anna Jauch, Véronique Pantesco, John De Vos, Aubin Thomas, Charles Theillet,[...]. Nat Cell Biol 2009
342
20

DNA-RNA hybrids: the risks of DNA breakage during transcription.
Andrés Aguilera, Belén Gómez-González. Nat Struct Mol Biol 2017
84
20

Targeting the DNA Damage Response in Cancer.
Mark J O'Connor. Mol Cell 2015
729
20

The DNA Damaging Revolution: PARP Inhibitors and Beyond.
Timothy A Yap, Ruth Plummer, Nilofer S Azad, Thomas Helleday. Am Soc Clin Oncol Educ Book 2019
91
20

BRCA1 recruitment to transcriptional pause sites is required for R-loop-driven DNA damage repair.
Elodie Hatchi, Konstantina Skourti-Stathaki, Steffen Ventz, Luca Pinello, Angela Yen, Kinga Kamieniarz-Gdula, Stoil Dimitrov, Shailja Pathania, Kristine M McKinney, Matthew L Eaton,[...]. Mol Cell 2015
241
20

Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect.
Erica Salvati, Carlo Leonetti, Angela Rizzo, Marco Scarsella, Marcella Mottolese, Rossella Galati, Isabella Sperduti, Malcolm F G Stevens, Maurizio D'Incalci, Maria Blasco,[...]. J Clin Invest 2007
179
20

R Loops: From Physiological to Pathological Roles.
Tatiana García-Muse, Andrés Aguilera. Cell 2019
183
20

Chemotherapeutic drugs inhibit ribosome biogenesis at various levels.
Kaspar Burger, Bastian Mühl, Thomas Harasim, Michaela Rohrmoser, Anastassia Malamoussi, Mathias Orban, Markus Kellner, Anita Gruber-Eber, Elisabeth Kremmer, Michael Hölzel,[...]. J Biol Chem 2010
264
20

R-loop formation is a distinctive characteristic of unmethylated human CpG island promoters.
Paul A Ginno, Paul L Lott, Holly C Christensen, Ian Korf, Frédéric Chédin. Mol Cell 2012
471
20

The Dual Inhibition of RNA Pol I Transcription and PIM Kinase as a New Therapeutic Approach to Treat Advanced Prostate Cancer.
Richard J Rebello, Eric Kusnadi, Donald P Cameron, Helen B Pearson, Analia Lesmana, Jennifer R Devlin, Denis Drygin, Ashlee K Clark, Laura Porter, John Pedersen,[...]. Clin Cancer Res 2016
47
20

Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53.
Megan J Bywater, Gretchen Poortinga, Elaine Sanij, Nadine Hein, Abigail Peck, Carleen Cullinane, Meaghan Wall, Leonie Cluse, Denis Drygin, Kenna Anderes,[...]. Cancer Cell 2012
369
20


Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
20

Targeting the RNA Polymerase I Transcription for Cancer Therapy Comes of Age.
Rita Ferreira, John S Schneekloth, Konstantin I Panov, Katherine M Hannan, Ross D Hannan. Cells 2020
52
20

A targeting modality for destruction of RNA polymerase I that possesses anticancer activity.
Karita Peltonen, Laureen Colis, Hester Liu, Rishi Trivedi, Michael S Moubarek, Henna M Moore, Baoyan Bai, Michelle A Rudek, Charles J Bieberich, Marikki Laiho. Cancer Cell 2014
161
20

Transcriptional suppression of ribosomal DNA with phase separation.
Satoru Ide, Ryosuke Imai, Hiroko Ochi, Kazuhiro Maeshima. Sci Adv 2020
21
20

Inhibition of RNA polymerase I transcription initiation by CX-5461 activates non-canonical ATM/ATR signaling.
Jaclyn Quin, Keefe T Chan, Jennifer R Devlin, Donald P Cameron, Jeannine Diesch, Carleen Cullinane, Jessica Ahern, Amit Khot, Nadine Hein, Amee J George,[...]. Oncotarget 2016
61
20

Targeting the nucleolus for cancer intervention.
Jaclyn E Quin, Jennifer R Devlin, Donald Cameron, Kate M Hannan, Richard B Pearson, Ross D Hannan. Biochim Biophys Acta 2014
151
20

The RNA polymerase I transcription inhibitor CX-5461 cooperates with topoisomerase 1 inhibition by enhancing the DNA damage response in homologous recombination-proficient high-grade serous ovarian cancer.
Shunfei Yan, Jiachen Xuan, Natalie Brajanovski, Madeleine R C Tancock, Piyush B Madhamshettiwar, Kaylene J Simpson, Sarah Ellis, Jian Kang, Carleen Cullinane, Karen E Sheppard,[...]. Br J Cancer 2021
15
20

R-Loops as Cellular Regulators and Genomic Threats.
Madzia P Crossley, Michael Bocek, Karlene A Cimprich. Mol Cell 2019
259
20

G-quadruplexes and their regulatory roles in biology.
Daniela Rhodes, Hans J Lipps. Nucleic Acids Res 2015
761
20

G-quadruplex DNA drives genomic instability and represents a targetable molecular abnormality in ATRX-deficient malignant glioma.
Yuxiang Wang, Jie Yang, Aaron T Wild, Wei H Wu, Rachna Shah, Carla Danussi, Gregory J Riggins, Kasthuri Kannan, Erik P Sulman, Timothy A Chan,[...]. Nat Commun 2019
76
20

Topoisomerases as anticancer targets.
Justine L Delgado, Chao-Ming Hsieh, Nei-Li Chan, Hiroshi Hiasa. Biochem J 2018
155
20

G-quadruplex DNA as a molecular target for induced synthetic lethality in cancer cells.
Keith I E McLuckie, Marco Di Antonio, Heather Zecchini, Jian Xian, Carlos Caldas, Ben-Fillippo Krippendorff, David Tannahill, Christopher Lowe, Shankar Balasubramanian. J Am Chem Soc 2013
93
20

Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds.
Jutta Zimmer, Eliana M C Tacconi, Cecilia Folio, Sophie Badie, Manuela Porru, Kerstin Klare, Manuela Tumiati, Enni Markkanen, Swagata Halder, Anderson Ryan,[...]. Mol Cell 2016
126
20

A novel small molecule that alters shelterin integrity and triggers a DNA-damage response at telomeres.
Raphaël Rodriguez, Sebastian Müller, Justin A Yeoman, Chantal Trentesaux, Jean-François Riou, Shankar Balasubramanian. J Am Chem Soc 2008
266
20

The DNA-damage response in human biology and disease.
Stephen P Jackson, Jiri Bartek. Nature 2009
20

DNA secondary structures: stability and function of G-quadruplex structures.
Matthew L Bochman, Katrin Paeschke, Virginia A Zakian. Nat Rev Genet 2012
795
20


GammaH2AX and cancer.
William M Bonner, Christophe E Redon, Jennifer S Dickey, Asako J Nakamura, Olga A Sedelnikova, Stéphanie Solier, Yves Pommier. Nat Rev Cancer 2008
20

Small-molecule-induced DNA damage identifies alternative DNA structures in human genes.
Raphaël Rodriguez, Kyle M Miller, Josep V Forment, Charles R Bradshaw, Mehran Nikan, Sébastien Britton, Tobias Oelschlaegel, Blerta Xhemalce, Shankar Balasubramanian, Stephen P Jackson. Nat Chem Biol 2012
425
20

The Structure and Function of DNA G-Quadruplexes.
Jochen Spiegel, Santosh Adhikari, Shankar Balasubramanian. Trends Chem 2020
204
20


G-quadruplex-induced instability during leading-strand replication.
Judith Lopes, Aurèle Piazza, Rodrigo Bermejo, Barry Kriegsman, Arianna Colosio, Marie-Paule Teulade-Fichou, Marco Foiani, Alain Nicolas. EMBO J 2011
216
20

TOP2B: The First Thirty Years.
Caroline A Austin, Ka C Lee, Rebecca L Swan, Mushtaq M Khazeem, Catriona M Manville, Peter Cridland, Achim Treumann, Andrew Porter, Nick J Morris, Ian G Cowell. Int J Mol Sci 2018
46
20

A rapid and sensitive assay for DNA-protein covalent complexes in living cells.
Kostantin Kiianitsa, Nancy Maizels. Nucleic Acids Res 2013
62
20

Crystal structure of parallel quadruplexes from human telomeric DNA.
Gary N Parkinson, Michael P H Lee, Stephen Neidle. Nature 2002
13


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.