Daniel I Brierley, Guillaume de Lartigue. Br J Pharmacol 2022
Times Cited: 11
Times Cited: 11
Times Cited
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Glucagon-like peptide 1 (GLP-1).
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Semaglutide lowers body weight in rodents via distributed neural pathways.
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Once-Weekly Semaglutide in Adults with Overweight or Obesity.
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A role for glucagon-like peptide-1 in the central regulation of feeding.
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Central and peripheral GLP-1 systems independently suppress eating.
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The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss.
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Glucagon-like peptide-1-(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine.
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The diverse effects of brain glucagon-like peptide 1 receptors on ingestive behaviour.
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Brain GLP-1 and the regulation of food intake: GLP-1 action in the brain and its implications for GLP-1 receptor agonists in obesity treatment.
Stefan Trapp, Daniel I Brierley. Br J Pharmacol 2022
Stefan Trapp, Daniel I Brierley. Br J Pharmacol 2022
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A recombinant human glucagon-like peptide (GLP)-1-albumin protein (albugon) mimics peptidergic activation of GLP-1 receptor-dependent pathways coupled with satiety, gastrointestinal motility, and glucose homeostasis.
Laurie L Baggio, Qingling Huang, Theodore J Brown, Daniel J Drucker. Diabetes 2004
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Enhanced AMPA Receptor Trafficking Mediates the Anorexigenic Effect of Endogenous Glucagon-like Peptide-1 in the Paraventricular Hypothalamus.
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Preproglucagon Neurons in the Nucleus of the Solitary Tract Are the Main Source of Brain GLP-1, Mediate Stress-Induced Hypophagia, and Limit Unusually Large Intakes of Food.
Marie K Holt, James E Richards, Daniel R Cook, Daniel I Brierley, Diana L Williams, Frank Reimann, Fiona M Gribble, Stefan Trapp. Diabetes 2019
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2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans.
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Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1.
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Neuronal GLP1R mediates liraglutide's anorectic but not glucose-lowering effect.
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Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans.
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Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes.
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Evaluation of the incretin effect in humans using GIP and GLP-1 receptor antagonists.
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Physiology of the Incretin Hormones, GIP and GLP-1-Regulation of Release and Posttranslational Modifications.
Jens J Holst, Nicolai J Wewer Albrechtsen, Mette M Rosenkilde, Carolyn F Deacon. Compr Physiol 2019
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Actions of glucagon-like peptide-1 receptor ligands in the gut.
Jens Juul Holst, Daniel Bjørklund Andersen, Kaare Villum Grunddal. Br J Pharmacol 2022
Jens Juul Holst, Daniel Bjørklund Andersen, Kaare Villum Grunddal. Br J Pharmacol 2022
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Glucagon-like peptide-1 inhibits gastric emptying via vagal afferent-mediated central mechanisms.
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Intestinal glucagon-like peptide-1 effects on food intake: Physiological relevance and emerging mechanisms.
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Vascular, but not luminal, activation of FFAR1 (GPR40) stimulates GLP-1 secretion from isolated perfused rat small intestine.
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Hindbrain glucagon-like peptide-1 neurons track intake volume and contribute to injection stress-induced hypophagia in meal-entrained rats.
Alison D Kreisler, Linda Rinaman. Am J Physiol Regul Integr Comp Physiol 2016
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Synaptic Inputs to the Mouse Dorsal Vagal Complex and Its Resident Preproglucagon Neurons.
Marie K Holt, Lisa E Pomeranz, Kevin T Beier, Frank Reimann, Fiona M Gribble, Linda Rinaman. J Neurosci 2019
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Receptor gene expression of glucagon-like peptide-1, but not glucose-dependent insulinotropic polypeptide, in rat nodose ganglion cells.
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GLP-1 neurons form a local synaptic circuit within the rodent nucleus of the solitary tract.
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Knockdown of GLP-1 Receptors in Vagal Afferents Affects Normal Food Intake and Glycemia.
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The impact of short-chain fatty acids on GLP-1 and PYY secretion from the isolated perfused rat colon.
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Sensory Neurons that Detect Stretch and Nutrients in the Digestive System.
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Glucagon-like peptide-1 (GLP-1) receptors expressed on nerve terminals in the portal vein mediate the effects of endogenous GLP-1 on glucose tolerance in rats.
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Activation of murine pre-proglucagon-producing neurons reduces food intake and body weight.
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Glucagon-like peptide-1-responsive catecholamine neurons in the area postrema link peripheral glucagon-like peptide-1 with central autonomic control sites.
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Gut-Proglucagon-Derived Peptides Are Essential for Regulating Glucose Homeostasis in Mice.
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The effect of exogenous GLP-1 on food intake is lost in male truncally vagotomized subjects with pyloroplasty.
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Interoceptive stress activates glucagon-like peptide-1 neurons that project to the hypothalamus.
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Distribution of pre-pro-glucagon and glucagon-like peptide-1 receptor messenger RNAs in the rat central nervous system.
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Preproglucagon neurons project widely to autonomic control areas in the mouse brain.
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Revisiting the Complexity of GLP-1 Action from Sites of Synthesis to Receptor Activation.
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The inhibitory effects of peripheral administration of peptide YY(3-36) and glucagon-like peptide-1 on food intake are attenuated by ablation of the vagal-brainstem-hypothalamic pathway.
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Pharmacology, physiology, and mechanisms of incretin hormone action.
Jonathan E Campbell, Daniel J Drucker. Cell Metab 2013
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Evidence that intestinal glucagon-like peptide-1 plays a physiological role in satiety.
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