Chloé Geoffroy, Pierre Paoletti, Laetitia Mony. J Physiol 2022
Times Cited: 5
Times Cited: 5
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Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function.
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Increased NMDA current and spine density in mice lacking the NMDA receptor subunit NR3A.
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GluN2A NMDA Receptor Enhancement Improves Brain Oscillations, Synchrony, and Cognitive Functions in Dravet Syndrome and Alzheimer's Disease Models.
Jesse E Hanson, Keran Ma, Justin Elstrott, Martin Weber, Sandrine Saillet, Abdullah S Khan, Jeffrey Simms, Benjamin Liu, Thomas A Kim, Gui-Qiu Yu,[...]. Cell Rep 2020
Jesse E Hanson, Keran Ma, Justin Elstrott, Martin Weber, Sandrine Saillet, Abdullah S Khan, Jeffrey Simms, Benjamin Liu, Thomas A Kim, Gui-Qiu Yu,[...]. Cell Rep 2020
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Age-dependent effects on social interaction of NMDA GluN2A receptor subtype-selective antagonism.
Torrian L Green, Jessica A Burket, Stephen I Deutsch. Brain Res Bull 2016
Torrian L Green, Jessica A Burket, Stephen I Deutsch. Brain Res Bull 2016
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GluN2A versus GluN2B: twins, but quite different.
Xiao-Min Zhang, Jian-Hong Luo. Neurosci Bull 2013
Xiao-Min Zhang, Jian-Hong Luo. Neurosci Bull 2013
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Glutamate receptor ion channels: structure, regulation, and function.
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Stephen F Traynelis, Lonnie P Wollmuth, Chris J McBain, Frank S Menniti, Katie M Vance, Kevin K Ogden, Kasper B Hansen, Hongjie Yuan, Scott J Myers, Ray Dingledine. Pharmacol Rev 2010
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NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease.
Pierre Paoletti, Camilla Bellone, Qiang Zhou. Nat Rev Neurosci 2013
Pierre Paoletti, Camilla Bellone, Qiang Zhou. Nat Rev Neurosci 2013
40
Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits.
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Subunit-selective allosteric inhibition of glycine binding to NMDA receptors.
Kasper B Hansen, Kevin K Ogden, Stephen F Traynelis. J Neurosci 2012
Kasper B Hansen, Kevin K Ogden, Stephen F Traynelis. J Neurosci 2012
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NMDARs in Cell Survival and Death: Implications in Stroke Pathogenesis and Treatment.
Yang Ge, Wenlin Chen, Peter Axerio-Cilies, Yu Tian Wang. Trends Mol Med 2020
Yang Ge, Wenlin Chen, Peter Axerio-Cilies, Yu Tian Wang. Trends Mol Med 2020
40
Distinct roles of GRIN2A and GRIN2B variants in neurological conditions.
Scott J Myers, Hongjie Yuan, Jing-Qiong Kang, Francis Chee Kuan Tan, Stephen F Traynelis, Chian-Ming Low. F1000Res 2019
Scott J Myers, Hongjie Yuan, Jing-Qiong Kang, Francis Chee Kuan Tan, Stephen F Traynelis, Chian-Ming Low. F1000Res 2019
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Influence of GluN2 subunit identity on NMDA receptor function.
D J A Wyllie, M R Livesey, G E Hardingham. Neuropharmacology 2013
D J A Wyllie, M R Livesey, G E Hardingham. Neuropharmacology 2013
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Metabotropic functions of the NMDA receptor and an evolving rationale for exploring NR2A-selective positive allosteric modulators for the treatment of autism spectrum disorder.
Jessica A Burket, Stephen I Deutsch. Prog Neuropsychopharmacol Biol Psychiatry 2019
Jessica A Burket, Stephen I Deutsch. Prog Neuropsychopharmacol Biol Psychiatry 2019
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Increasing endogenous activity of NMDARs on GABAergic neurons increases inhibition, alters sensory processing and prevents noise-induced tinnitus.
Di Deng, Samer Masri, Lulu Yao, Xiaoyan Ma, Xuebing Cao, Sungchil Yang, Shaowen Bao, Qiang Zhou. Sci Rep 2020
Di Deng, Samer Masri, Lulu Yao, Xiaoyan Ma, Xuebing Cao, Sungchil Yang, Shaowen Bao, Qiang Zhou. Sci Rep 2020
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NMDA receptor hypofunction, parvalbumin-positive neurons, and cortical gamma oscillations in schizophrenia.
Guillermo Gonzalez-Burgos, David A Lewis. Schizophr Bull 2012
Guillermo Gonzalez-Burgos, David A Lewis. Schizophr Bull 2012
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Higher ambient synaptic glutamate at inhibitory versus excitatory neurons differentially impacts NMDA receptor activity.
Lulu Yao, Teddy Grand, Jesse E Hanson, Pierre Paoletti, Qiang Zhou. Nat Commun 2018
Lulu Yao, Teddy Grand, Jesse E Hanson, Pierre Paoletti, Qiang Zhou. Nat Commun 2018
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Neonatal exposure to epidermal growth factor induces dopamine D2-like receptor supersensitivity in adult sensorimotor gating.
Hidekazu Sotoyama, Hisaaki Namba, Nobuyuki Takei, Hiroyuki Nawa. Psychopharmacology (Berl) 2007
Hidekazu Sotoyama, Hisaaki Namba, Nobuyuki Takei, Hiroyuki Nawa. Psychopharmacology (Berl) 2007
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Dopamine D2 receptor occupancy and clinical effects: a systematic review and pooled analysis.
Hiroyuki Uchida, Hiroyoshi Takeuchi, Ariel Graff-Guerrero, Takefumi Suzuki, Koichiro Watanabe, David C Mamo. J Clin Psychopharmacol 2011
Hiroyuki Uchida, Hiroyoshi Takeuchi, Ariel Graff-Guerrero, Takefumi Suzuki, Koichiro Watanabe, David C Mamo. J Clin Psychopharmacol 2011
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Akathisia and Newer Second-Generation Antipsychotic Drugs: A Review of Current Evidence.
Constance L Chow, Nour K Kadouh, Jolene R Bostwick, Amy M VandenBerg. Pharmacotherapy 2020
Constance L Chow, Nour K Kadouh, Jolene R Bostwick, Amy M VandenBerg. Pharmacotherapy 2020
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Role of dopamine projections from ventral tegmental area to nucleus accumbens and medial prefrontal cortex in reinforcement behaviors assessed using optogenetic manipulation.
Xiao Han, Man-Yi Jing, Tai-Yun Zhao, Ning Wu, Rui Song, Jin Li. Metab Brain Dis 2017
Xiao Han, Man-Yi Jing, Tai-Yun Zhao, Ning Wu, Rui Song, Jin Li. Metab Brain Dis 2017
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Multiple D2 heteroreceptor complexes: new targets for treatment of schizophrenia.
Dasiel O Borroto-Escuela, Julia Pintsuk, Thorsten Schäfer, Kristina Friedland, Luca Ferraro, Sergio Tanganelli, Fang Liu, Kjell Fuxe. Ther Adv Psychopharmacol 2016
Dasiel O Borroto-Escuela, Julia Pintsuk, Thorsten Schäfer, Kristina Friedland, Luca Ferraro, Sergio Tanganelli, Fang Liu, Kjell Fuxe. Ther Adv Psychopharmacol 2016
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Deficits in the extinction of ethanol-seeking behavior following chronic intermittent ethanol exposure are attenuated with positive allosteric modulation of mGlu5.
J T Gass, J T McGonigal, L J Chandler. Neuropharmacology 2017
J T Gass, J T McGonigal, L J Chandler. Neuropharmacology 2017
20
cAMP response element binding protein phosphorylation in nucleus accumbens underlies sustained recovery of sensorimotor gating following repeated D₂-like receptor agonist treatment in rats.
Alison K Berger, Thomas Green, Steven J Siegel, Eric J Nestler, Ronald P Hammer. Biol Psychiatry 2011
Alison K Berger, Thomas Green, Steven J Siegel, Eric J Nestler, Ronald P Hammer. Biol Psychiatry 2011
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Neurocognitive Development of Motivated Behavior: Dynamic Changes across Childhood and Adolescence.
Dylan G Gee, Kevin G Bath, Carolyn M Johnson, Heidi C Meyer, Vishnu P Murty, Wouter van den Bos, Catherine A Hartley. J Neurosci 2018
Dylan G Gee, Kevin G Bath, Carolyn M Johnson, Heidi C Meyer, Vishnu P Murty, Wouter van den Bos, Catherine A Hartley. J Neurosci 2018
20
Subchronic MK-801 treatment during adolescence induces long-term, not permanent, excitatory-inhibitory imbalance in the rat hippocampus.
Yu-Nu Ma, Ya-Xin Sun, Ting Wang, Han Wang, Yue Zhang, Yun-Ai Su, Ji-Tao Li, Tian-Mei Si. Eur J Pharmacol 2020
Yu-Nu Ma, Ya-Xin Sun, Ting Wang, Han Wang, Yue Zhang, Yun-Ai Su, Ji-Tao Li, Tian-Mei Si. Eur J Pharmacol 2020
20
Dose-dependent effect of CDPPB, the mGluR5 positive allosteric modulator, on recognition memory is associated with GluR1 and CREB phosphorylation in the prefrontal cortex and hippocampus.
Jason M Uslaner, Sophie Parmentier-Batteur, Rosemarie B Flick, Nathaniel O Surles, June S H Lam, Caitlyn H McNaughton, Marlene A Jacobson, Pete H Hutson. Neuropharmacology 2009
Jason M Uslaner, Sophie Parmentier-Batteur, Rosemarie B Flick, Nathaniel O Surles, June S H Lam, Caitlyn H McNaughton, Marlene A Jacobson, Pete H Hutson. Neuropharmacology 2009
20
A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral models.
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Cognitive and prepulse inhibition deficits in psychometrically high schizotypal subjects in the general population: relevance to schizophrenia research.
Stella G Giakoumaki. J Int Neuropsychol Soc 2012
Stella G Giakoumaki. J Int Neuropsychol Soc 2012
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Positive allosteric modulators of type 5 metabotropic glutamate receptors (mGluR5) and their therapeutic potential for the treatment of CNS disorders.
Richard M Cleva, M Foster Olive. Molecules 2011
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20
Impaired prepulse inhibition of acoustic startle in obsessive-compulsive disorder.
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Klaus Hoenig, Andrea Hochrein, Boris B Quednow, Wolfgang Maier, Michael Wagner. Biol Psychiatry 2005
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The adenosine A(2A) receptor agonist CGS 21680 alleviates auditory sensorimotor gating deficits and increases in accumbal CREB in rats neonatally treated with quinpirole.
Russell W Brown, Pradeep G Bhide, W Drew Gill, Loren D Peeters. Psychopharmacology (Berl) 2020
Russell W Brown, Pradeep G Bhide, W Drew Gill, Loren D Peeters. Psychopharmacology (Berl) 2020
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Targeting mGlu Receptors for Optimization of Antipsychotic Activity and Disease-Modifying Effect in Schizophrenia.
Ferdinando Nicoletti, Rosamaria Orlando, Luisa Di Menna, Milena Cannella, Serena Notartomaso, Giada Mascio, Luisa Iacovelli, Francesco Matrisciano, Francesco Fazio, Filippo Caraci,[...]. Front Psychiatry 2019
Ferdinando Nicoletti, Rosamaria Orlando, Luisa Di Menna, Milena Cannella, Serena Notartomaso, Giada Mascio, Luisa Iacovelli, Francesco Matrisciano, Francesco Fazio, Filippo Caraci,[...]. Front Psychiatry 2019
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Enhanced CRFR1-Dependent Regulation of a Ventral Tegmental Area to Prelimbic Cortex Projection Establishes Susceptibility to Stress-Induced Cocaine Seeking.
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Discovery of VU0409551/JNJ-46778212: An mGlu5 Positive Allosteric Modulator Clinical Candidate Targeting Schizophrenia.
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Susana Conde-Ceide, Carlos M Martínez-Viturro, Jesús Alcázar, Pedro M Garcia-Barrantes, Hilde Lavreysen, Claire Mackie, Paige N Vinson, Jerri M Rook, Thomas M Bridges, J Scott Daniels,[...]. ACS Med Chem Lett 2015
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Neurodevelopmental animal models of schizophrenia: effects on prepulse inhibition.
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Prepulse inhibition and genetic mouse models of schizophrenia.
Susan B Powell, Xianjin Zhou, Mark A Geyer. Behav Brain Res 2009
Susan B Powell, Xianjin Zhou, Mark A Geyer. Behav Brain Res 2009
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Positive allosteric modulation of mGluR5 receptors facilitates extinction of a cocaine contextual memory.
Justin T Gass, M Foster Olive. Biol Psychiatry 2009
Justin T Gass, M Foster Olive. Biol Psychiatry 2009
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Animal models of deficient sensorimotor gating: what we know, what we think we know, and what we hope to know soon.
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mGluR5 positive allosteric modulation enhances extinction learning following cocaine self-administration.
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Histamine H3 receptor activation reduces the impairment in prepulse inhibition (PPI) of the acoustic startle response and Akt phosphorylation induced by MK-801 (dizocilpine), antagonist at N-Methyl-d-Aspartate (NMDA) receptors.
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Progress towards validating the NMDA receptor hypofunction hypothesis of schizophrenia.
Craig W Lindsley, William D Shipe, Scott E Wolkenberg, Cory R Theberge, David L Williams, Cyrille Sur, Gene G Kinney. Curr Top Med Chem 2006
Craig W Lindsley, William D Shipe, Scott E Wolkenberg, Cory R Theberge, David L Williams, Cyrille Sur, Gene G Kinney. Curr Top Med Chem 2006
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Psychotomimetic effects of different doses of MK-801 and the underlying mechanisms in a selective memory impairment model.
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Neuroimaging Biomarkers in Schizophrenia.
Nina V Kraguljac, William M McDonald, Alik S Widge, Carolyn I Rodriguez, Mauricio Tohen, Charles B Nemeroff. Am J Psychiatry 2021
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The mGluR5 positive allosteric modulator, CDPPB, ameliorates pathology and phenotypic signs of a mouse model of Huntington's disease.
J G Doria, J M de Souza, J N Andrade, H A Rodrigues, I M Guimaraes, T G Carvalho, C Guatimosim, T Dobransky, F M Ribeiro. Neurobiol Dis 2015
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A novel allosteric modulator of the cannabinoid CB1 receptor ameliorates hyperdopaminergia endophenotypes in rodent models.
Catharine A Mielnik, Kim S Sugamori, David B Finlay, Hayley H A Thorpe, Matthieu Schapira, Nirunthan Sivananthan, Chun Kit Li, Vincent M Lam, Sean Harrington, Mostafa H Abdelrahman,[...]. Neuropsychopharmacology 2021
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Adolescent alcohol exposure reduces behavioral flexibility, promotes disinhibition, and increases resistance to extinction of ethanol self-administration in adulthood.
Justin T Gass, William Bailey Glen, Justin T McGonigal, Heather Trantham-Davidson, Marcelo F Lopez, Patrick K Randall, Richard Yaxley, Stan B Floresco, L Judson Chandler. Neuropsychopharmacology 2014
Justin T Gass, William Bailey Glen, Justin T McGonigal, Heather Trantham-Davidson, Marcelo F Lopez, Patrick K Randall, Richard Yaxley, Stan B Floresco, L Judson Chandler. Neuropsychopharmacology 2014
20
Metabotropic glutamate receptors in the basal ganglia motor circuit.
P Jeffrey Conn, Giuseppe Battaglia, Michael J Marino, Ferdinando Nicoletti. Nat Rev Neurosci 2005
P Jeffrey Conn, Giuseppe Battaglia, Michael J Marino, Ferdinando Nicoletti. Nat Rev Neurosci 2005
20
Schizophrenia and substance abuse comorbidity: nicotine addiction and the neonatal quinpirole model.
Russell W Brown, Amanda M Maple, Marla K Perna, A Brianna Sheppard, Zackary A Cope, Richard M Kostrzewa. Dev Neurosci 2012
Russell W Brown, Amanda M Maple, Marla K Perna, A Brianna Sheppard, Zackary A Cope, Richard M Kostrzewa. Dev Neurosci 2012
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N-methyl-D-aspartate antagonists as drug models of schizophrenia: a surprising link to tobacco smoking.
Edward F Domino, Diana Mirzoyan, Hideo Tsukada. Prog Neuropsychopharmacol Biol Psychiatry 2004
Edward F Domino, Diana Mirzoyan, Hideo Tsukada. Prog Neuropsychopharmacol Biol Psychiatry 2004
20
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.