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A novel machine learning-based approach for the computational functional assessment of pharmacogenomic variants.
Maria-Theodora Pandi, Maria Koromina, Iordanis Tsafaridis, Sotirios Patsilinakos, Evangelos Christoforou, Peter J van der Spek, George P Patrinos. Hum Genomics 2021
Times Cited: 6






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List of co-cited articles
32 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Rare genetic variants in cellular transporters, metabolic enzymes, and nuclear receptors can be important determinants of interindividual differences in drug response.
Mikael Kozyra, Magnus Ingelman-Sundberg, Volker M Lauschke. Genet Med 2017
142
4
66

Key challenges for next-generation pharmacogenomics: Science & Society series on Science and Drugs.
Kostas Kampourakis, Effy Vayena, Christina Mitropoulou, Ron H van Schaik, David N Cooper, Joseph Borg, George P Patrinos. EMBO Rep 2014
30
3
50

Integrating rare genetic variants into pharmacogenetic drug response predictions.
Magnus Ingelman-Sundberg, Souren Mkrtchian, Yitian Zhou, Volker M Lauschke. Hum Genomics 2018
105
3
50

Rare genetic variability in human drug target genes modulates drug response and can guide precision medicine.
Yitian Zhou, Gabriel Herras Arribas, Ainoleena Turku, Tuuli Jürgenson, Souren Mkrtchian, Kristi Krebs, Yi Wang, Barbora Svobodova, Lili Milani, Gunnar Schulte,[...]. Sci Adv 2021
8
3
50

Population-scale predictions of DPD and TPMT phenotypes using a quantitative pharmacogene-specific ensemble classifier.
Yitian Zhou, Carolina Dagli Hernandez, Volker M Lauschke. Br J Cancer 2020
17
3
50

Computational Methods for the Pharmacogenetic Interpretation of Next Generation Sequencing Data.
Yitian Zhou, Kohei Fujikura, Souren Mkrtchian, Volker M Lauschke. Front Pharmacol 2018
42
3
50

Computational Tools to Assess the Functional Consequences of Rare and Noncoding Pharmacogenetic Variability.
Yitian Zhou, Volker M Lauschke. Clin Pharmacol Ther 2021
10
3
50

An optimized prediction framework to assess the functional impact of pharmacogenetic variants.
Yitian Zhou, Souren Mkrtchian, Masaki Kumondai, Masahiro Hiratsuka, Volker M Lauschke. Pharmacogenomics J 2019
67
3
50

The Ensembl Variant Effect Predictor.
William McLaren, Laurent Gil, Sarah E Hunt, Harpreet Singh Riat, Graham R S Ritchie, Anja Thormann, Paul Flicek, Fiona Cunningham. Genome Biol 2016
2832
2
33

Prevalence of pharmacogenomic variants in 100 pharmacogenes among Southeast Asian populations under the collaboration of the Southeast Asian Pharmacogenomics Research Network (SEAPharm).
Chakkaphan Runcharoen, Koya Fukunaga, Insee Sensorn, Nareenart Iemwimangsa, Sommon Klumsathian, Hang Tong, Nam Sy Vo, Ly Le, Tin Maung Hlaing, Myo Thant,[...]. Hum Genome Var 2021
13
2
33

Unveiling the guidance heterogeneity for genome-informed drug treatment interventions among regulatory bodies and research consortia.
Stefania Koutsilieri, Foteini Tzioufa, Despoina-Christina Sismanoglou, George P Patrinos. Pharmacol Res 2020
20
2
33

Pharmacogenomics of GPCR Drug Targets.
Alexander S Hauser, Sreenivas Chavali, Ikuo Masuho, Leonie J Jahn, Kirill A Martemyanov, David E Gloriam, M Madan Babu. Cell 2018
299
2
33

A method and server for predicting damaging missense mutations.
Ivan A Adzhubei, Steffen Schmidt, Leonid Peshkin, Vasily E Ramensky, Anna Gerasimova, Peer Bork, Alexey S Kondrashov, Shamil R Sunyaev. Nat Methods 2010
9088
2
33

Clinical implementation of drug metabolizing gene-based therapeutic interventions worldwide.
Evangelia Eirini Tsermpini, Zeina N Al-Mahayri, Bassam R Ali, George P Patrinos. Hum Genet 2022
4
2
50

Emerging strategies to bridge the gap between pharmacogenomic research and its clinical implementation.
Volker M Lauschke, Magnus Ingelman-Sundberg. NPJ Genom Med 2020
24
2
33

Population pharmacogenomics: an update on ethnogeographic differences and opportunities for precision public health.
Yitian Zhou, Volker M Lauschke. Hum Genet 2022
4
2
50

Pharmacogenetics Guidelines: Overview and Comparison of the DPWG, CPIC, CPNDS, and RNPGx Guidelines.
Heshu Abdullah-Koolmees, Antonius M van Keulen, Marga Nijenhuis, Vera H M Deneer. Front Pharmacol 2021
39
2
33

Analysis of population-specific pharmacogenomic variants using next-generation sequencing data.
Eunyong Ahn, Taesung Park. Sci Rep 2017
16
2
33

The genetic landscape of the human solute carrier (SLC) transporter superfamily.
Lena Schaller, Volker M Lauschke. Hum Genet 2019
57
2
33

The global spectrum of protein-coding pharmacogenomic diversity.
G E B Wright, B Carleton, M R Hayden, C J D Ross. Pharmacogenomics J 2018
51
2
33

Pharmacogenomic Biomarkers for Improved Drug Therapy-Recent Progress and Future Developments.
Volker M Lauschke, Lili Milani, Magnus Ingelman-Sundberg. AAPS J 2017
78
2
33

Genetic variability and population diversity of the human SLCO (OATP) transporter family.
Boyao Zhang, Volker M Lauschke. Pharmacol Res 2019
25
2
33

Heritability of metoprolol and torsemide pharmacokinetics.
J Matthaei, J Brockmöller, M V Tzvetkov, D Sehrt, C Sachse-Seeboth, J B Hjelmborg, S Möller, U Halekoh, U Hofmann, M Schwab,[...]. Clin Pharmacol Ther 2015
41
2
33

Toward predicting CYP2D6-mediated variable drug response from CYP2D6 gene sequencing data.
Maaike van der Lee, William G Allard, Rolf H A M Vossen, Renée F Baak-Pablo, Roberta Menafra, Birgit A L M Deiman, Maarten J Deenen, Patrick Neven, Inger Johansson, Stefano Gastaldello,[...]. Sci Transl Med 2021
19
2
33

Transfer learning enables prediction of CYP2D6 haplotype function.
Gregory McInnes, Rachel Dalton, Katrin Sangkuhl, Michelle Whirl-Carrillo, Seung-Been Lee, Philip S Tsao, Andrea Gaedigk, Russ B Altman, Erica L Woodahl. PLoS Comput Biol 2020
18
2
33

Long-read human genome sequencing and its applications.
Glennis A Logsdon, Mitchell R Vollger, Evan E Eichler. Nat Rev Genet 2020
224
2
33

An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people.
Matthew R Nelson, Daniel Wegmann, Margaret G Ehm, Darren Kessner, Pamela St Jean, Claudio Verzilli, Judong Shen, Zhengzheng Tang, Silviu-Alin Bacanu, Dana Fraser,[...]. Science 2012
468
2
33

Ethnogeographic and inter-individual variability of human ABC transporters.
Qingyang Xiao, Yitian Zhou, Volker M Lauschke. Hum Genet 2020
28
2
33

Worldwide Distribution of Cytochrome P450 Alleles: A Meta-analysis of Population-scale Sequencing Projects.
Y Zhou, M Ingelman-Sundberg, V M Lauschke. Clin Pharmacol Ther 2017
303
2
33

Genetic variation in human drug-related genes.
Charlotta Pauline Irmgard Schärfe, Roman Tremmel, Matthias Schwab, Oliver Kohlbacher, Debora Susan Marks. Genome Med 2017
62
2
33

Gene-Specific Variant Classifier (DPYD-Varifier) to Identify Deleterious Alleles of Dihydropyrimidine Dehydrogenase.
Shikshya Shrestha, Cheng Zhang, Calvin R Jerde, Qian Nie, Hu Li, Steven M Offer, Robert B Diasio. Clin Pharmacol Ther 2018
30
2
33

Evaluation of Current Regulation and Guidelines of Pharmacogenomic Drug Labels: Opportunities for Improvements.
Rawan Shekhani, Linda Steinacher, Jesse J Swen, Magnus Ingelman-Sundberg. Clin Pharmacol Ther 2020
35
2
33

Genomics and Pharmacogenomics Knowledge, Attitude and Practice of Pharmacists Working in United Arab Emirates: Findings from Focus Group Discussions-A Qualitative Study.
Azhar T Rahma, Iffat Elbarazi, Bassam R Ali, George P Patrinos, Luai A Ahmed, Fatma Al Maskari. J Pers Med 2020
11
1
16

A quantitative analysis of the mass media coverage of genomics medicine in China: a call for science journalism in the developing world.
Feifei Zhao, Yan Chen, Siqi Ge, Xinwei Yu, Shuang Shao, Michael Black, Youxin Wang, Jie Zhang, Manshu Song, Wei Wang. OMICS 2014
13
1
16

Realities and expectations of pharmacogenomics and personalized medicine: impact of translating genetic knowledge into clinical practice.
Alessio Squassina, Mirko Manchia, Vangelis G Manolopoulos, Mehmet Artac, Christina Lappa-Manakou, Sophia Karkabouna, Konstantinos Mitropoulos, Maria Del Zompo, George P Patrinos. Pharmacogenomics 2010
84
1
16

Critical appraisal of the views of healthcare professionals with respect to pharmacogenomics and personalized medicine in Greece.
Yuan Mai, Christina Mitropoulou, Xanthi E Papadopoulou, Athanassios Vozikis, David N Cooper, Ron H van Schaik, George P Patrinos. Per Med 2014
27
1
16

Genetics, genomics and society: the responsibilities of scientists for science communication and education.
Thomas Ac Reydon, Kostas Kampourakis, George P Patrinos. Per Med 2012
15
1
16

Ascertainment and critical assessment of the views of the general public and healthcare professionals on nutrigenomics in Greece.
Cristiana Pavlidis, Angeliki Karamitri, Aglaia Barakou, David N Cooper, Konstantinos Poulas, Stavros Topouzis, George P Patrinos. Per Med 2012
16
1
16

Genetic tests obtainable through pharmacies: the good, the bad, and the ugly.
George P Patrinos, Darrol J Baker, Fahd Al-Mulla, Vasilis Vasiliou, David N Cooper. Hum Genomics 2013
26
1
16

Whole genome sequencing in pharmacogenomics.
Theodora Katsila, George P Patrinos. Front Pharmacol 2015
27
1
16

Comparisons between protocols and publications of case-control studies: analysis of potential causes of non-reproducibility and recommendations for enhancing the quality of personalization in healthcare.
Haifeng Hou, Guoyong Ding, Xuan Zhao, Zixiu Meng, Jiangmin Xu, Zheng Guo, Yulu Zheng, Dong Li, Wei Wang. EPMA J 2019
1
1
100

Nutrigenomics: A controversy.
Cristiana Pavlidis, George P Patrinos, Theodora Katsila. Appl Transl Genom 2015
9
1
16

Assessment of the pharmacogenomics educational environment in Southeast Europe.
Claudia Pisanu, Evangelia-Eirini Tsermpini, Eirini Mavroidi, Theodora Katsila, George P Patrinos, Alessio Squassina. Public Health Genomics 2014
28
1
16

A critical view of the general public's awareness and physicians' opinion of the trends and potential pitfalls of genetic testing in Greece.
Yuan Mai, Theodora Koromila, Aggeliki Sagia, David N Cooper, Georgios Vlachopoulos, George Lagoumintzis, Panagoula Kollia, Konstantinos Poulas, Vlassios Stathakopoulos, George P Patrinos. Per Med 2011
36
1
16

Impact of biobanks on research outcomes in rare diseases: a systematic review.
Monique Garcia, Jenny Downs, Alyce Russell, Wei Wang. Orphanet J Rare Dis 2018
17
1
16

Current needs for human and medical genomics research infrastructure in low and middle income countries.
Diego A Forero, Ambroise Wonkam, Wei Wang, Paul Laissue, Catalina López-Correa, Juan C Fernández-López, Raja Mugasimangalam, George Perry. J Med Genet 2016
12
1
16

Continuous pharmacogenomics and genomic medicine education for healthcare professionals through electronic educational courses.
Evangelia-Eirini Tsermpini, Theano Stamopoulou, Zoe Kordou, Evaggelia Barba, Stavroula Siamoglou, Andreas Stathoulias, George P Patrinos. Per Med 2019
6
1
16

Precision Medicine and Rare Genetic Variants.
Volker M Lauschke, Magnus Ingelman-Sundberg. Trends Pharmacol Sci 2016
43
1
16

Development and validation of a fast and sensitive UPLC-MS/MS method for the quantification of six probe metabolites for the in vitro determination of cytochrome P450 activity.
Lies De Bock, Koen Boussery, Pieter Colin, Julie De Smet, Huybrecht T'jollyn, Jan Van Bocxlaer. Talanta 2012
31
1
16

How to Consider Rare Genetic Variants in Personalized Drug Therapy.
Volker M Lauschke, Magnus Ingelman-Sundberg. Clin Pharmacol Ther 2018
28
1
16


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.

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