Sonja Blumenstock, Elena Katharina Schulz-Trieglaff, Kerstin Voelkl, Anna-Lena Bolender, Paul Lapios, Jana Lindner, Mark S Hipp, F Ulrich Hartl, Rüdiger Klein, Irina Dudanova. EMBO J 2021
Times Cited: 5
Times Cited: 5
Times Cited
Times Co-cited
Similarity
The biology of proteostasis in aging and disease.
Johnathan Labbadia, Richard I Morimoto. Annu Rev Biochem 2015
Johnathan Labbadia, Richard I Morimoto. Annu Rev Biochem 2015
80
Firefly luciferase mutants as sensors of proteome stress.
Rajat Gupta, Prasad Kasturi, Andreas Bracher, Christian Loew, Min Zheng, Adriana Villella, Dan Garza, F Ulrich Hartl, Swasti Raychaudhuri. Nat Methods 2011
Rajat Gupta, Prasad Kasturi, Andreas Bracher, Christian Loew, Min Zheng, Adriana Villella, Dan Garza, F Ulrich Hartl, Swasti Raychaudhuri. Nat Methods 2011
80
A chaperome subnetwork safeguards proteostasis in aging and neurodegenerative disease.
Marc Brehme, Cindy Voisine, Thomas Rolland, Shinichiro Wachi, James H Soper, Yitan Zhu, Kai Orton, Adriana Villella, Dan Garza, Marc Vidal,[...]. Cell Rep 2014
Marc Brehme, Cindy Voisine, Thomas Rolland, Shinichiro Wachi, James H Soper, Yitan Zhu, Kai Orton, Adriana Villella, Dan Garza, Marc Vidal,[...]. Cell Rep 2014
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The proteostasis network and its decline in ageing.
Mark S Hipp, Prasad Kasturi, F Ulrich Hartl. Nat Rev Mol Cell Biol 2019
Mark S Hipp, Prasad Kasturi, F Ulrich Hartl. Nat Rev Mol Cell Biol 2019
60
Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging.
Anat Ben-Zvi, Elizabeth A Miller, Richard I Morimoto. Proc Natl Acad Sci U S A 2009
Anat Ben-Zvi, Elizabeth A Miller, Richard I Morimoto. Proc Natl Acad Sci U S A 2009
60
The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans.
James F Morley, Heather R Brignull, Jill J Weyers, Richard I Morimoto. Proc Natl Acad Sci U S A 2002
James F Morley, Heather R Brignull, Jill J Weyers, Richard I Morimoto. Proc Natl Acad Sci U S A 2002
60
The nucleolus functions as a phase-separated protein quality control compartment.
F Frottin, F Schueder, S Tiwary, R Gupta, R Körner, T Schlichthaerle, J Cox, R Jungmann, F U Hartl, M S Hipp. Science 2019
F Frottin, F Schueder, S Tiwary, R Gupta, R Körner, T Schlichthaerle, J Cox, R Jungmann, F U Hartl, M S Hipp. Science 2019
40
Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions.
Heidi Olzscha, Sonya M Schermann, Andreas C Woerner, Stefan Pinkert, Michael H Hecht, Gian G Tartaglia, Michele Vendruscolo, Manajit Hayer-Hartl, F Ulrich Hartl, R Martin Vabulas. Cell 2011
Heidi Olzscha, Sonya M Schermann, Andreas C Woerner, Stefan Pinkert, Michael H Hecht, Gian G Tartaglia, Michele Vendruscolo, Manajit Hayer-Hartl, F Ulrich Hartl, R Martin Vabulas. Cell 2011
40
The heat shock response: systems biology of proteotoxic stress in aging and disease.
Richard I Morimoto. Cold Spring Harb Symp Quant Biol 2011
Richard I Morimoto. Cold Spring Harb Symp Quant Biol 2011
40
Pathways of cellular proteostasis in aging and disease.
Courtney L Klaips, Gopal Gunanathan Jayaraj, F Ulrich Hartl. J Cell Biol 2018
Courtney L Klaips, Gopal Gunanathan Jayaraj, F Ulrich Hartl. J Cell Biol 2018
40
HSF1 deficiency and impaired HSP90-dependent protein folding are hallmarks of aneuploid human cells.
Neysan Donnelly, Verena Passerini, Milena Dürrbaum, Silvia Stingele, Zuzana Storchová. EMBO J 2014
Neysan Donnelly, Verena Passerini, Milena Dürrbaum, Silvia Stingele, Zuzana Storchová. EMBO J 2014
40
In vivo aspects of protein folding and quality control.
David Balchin, Manajit Hayer-Hartl, F Ulrich Hartl. Science 2016
David Balchin, Manajit Hayer-Hartl, F Ulrich Hartl. Science 2016
40
A transgenic mouse model of the ubiquitin/proteasome system.
Kristina Lindsten, Victoria Menéndez-Benito, Maria G Masucci, Nico P Dantuma. Nat Biotechnol 2003
Kristina Lindsten, Victoria Menéndez-Benito, Maria G Masucci, Nico P Dantuma. Nat Biotechnol 2003
40
Molecular chaperones and neuronal proteostasis.
Heather L Smith, Wenwen Li, Michael E Cheetham. Semin Cell Dev Biol 2015
Heather L Smith, Wenwen Li, Michael E Cheetham. Semin Cell Dev Biol 2015
40
AgHalo: A Facile Fluorogenic Sensor to Detect Drug-Induced Proteome Stress.
Yu Liu, Matthew Fares, Noah P Dunham, Zi Gao, Kun Miao, Xueyuan Jiang, Samuel S Bollinger, Amie K Boal, Xin Zhang. Angew Chem Int Ed Engl 2017
Yu Liu, Matthew Fares, Noah P Dunham, Zi Gao, Kun Miao, Xueyuan Jiang, Samuel S Bollinger, Amie K Boal, Xin Zhang. Angew Chem Int Ed Engl 2017
40
A Fluorescence-Based Sensor Assay that Monitors General Protein Aggregation in Human Cells.
Marisa Pereira, Diogo Tomé, Ana S Domingues, Ana S Varanda, Cristiana Paulo, Manuel A S Santos, Ana R Soares. Biotechnol J 2018
Marisa Pereira, Diogo Tomé, Ana S Domingues, Ana S Varanda, Cristiana Paulo, Manuel A S Santos, Ana R Soares. Biotechnol J 2018
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A thiol probe for measuring unfolded protein load and proteostasis in cells.
Moore Z Chen, Nagaraj S Moily, Jessica L Bridgford, Rebecca J Wood, Mona Radwan, Trevor A Smith, Zhegang Song, Ben Zhong Tang, Leann Tilley, Xiaohong Xu,[...]. Nat Commun 2017
Moore Z Chen, Nagaraj S Moily, Jessica L Bridgford, Rebecca J Wood, Mona Radwan, Trevor A Smith, Zhegang Song, Ben Zhong Tang, Leann Tilley, Xiaohong Xu,[...]. Nat Commun 2017
40
A Molecular Chameleon for Mapping Subcellular Polarity in an Unfolded Proteome Environment.
Tze Cin Owyong, Pramod Subedi, Jieru Deng, Elizabeth Hinde, Jason J Paxman, Jonathan M White, Weisan Chen, Begoña Heras, Wallace W H Wong, Yuning Hong. Angew Chem Int Ed Engl 2020
Tze Cin Owyong, Pramod Subedi, Jieru Deng, Elizabeth Hinde, Jason J Paxman, Jonathan M White, Weisan Chen, Begoña Heras, Wallace W H Wong, Yuning Hong. Angew Chem Int Ed Engl 2020
40
A biosensor-based framework to measure latent proteostasis capacity.
Rebecca J Wood, Angelique R Ormsby, Mona Radwan, Dezerae Cox, Abhishek Sharma, Tobias Vöpel, Simon Ebbinghaus, Mikael Oliveberg, Gavin E Reid, Alex Dickson,[...]. Nat Commun 2018
Rebecca J Wood, Angelique R Ormsby, Mona Radwan, Dezerae Cox, Abhishek Sharma, Tobias Vöpel, Simon Ebbinghaus, Mikael Oliveberg, Gavin E Reid, Alex Dickson,[...]. Nat Commun 2018
40
Fast Fluorescence Lifetime Imaging Reveals the Aggregation Processes of α-Synuclein and Polyglutamine in Aging Caenorhabditis elegans.
Romain F Laine, Tessa Sinnige, Kai Yu Ma, Amanda J Haack, Chetan Poudel, Peter Gaida, Nathan Curry, Michele Perni, Ellen A A Nollen, Christopher M Dobson,[...]. ACS Chem Biol 2019
Romain F Laine, Tessa Sinnige, Kai Yu Ma, Amanda J Haack, Chetan Poudel, Peter Gaida, Nathan Curry, Michele Perni, Ellen A A Nollen, Christopher M Dobson,[...]. ACS Chem Biol 2019
40
Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones.
James F Morley, Richard I Morimoto. Mol Biol Cell 2004
James F Morley, Richard I Morimoto. Mol Biol Cell 2004
40
Progressive disruption of cellular protein folding in models of polyglutamine diseases.
Tali Gidalevitz, Anat Ben-Zvi, Kim H Ho, Heather R Brignull, Richard I Morimoto. Science 2006
Tali Gidalevitz, Anat Ben-Zvi, Kim H Ho, Heather R Brignull, Richard I Morimoto. Science 2006
40
Regulation of organismal proteostasis by transcellular chaperone signaling.
Patricija van Oosten-Hawle, Robert S Porter, Richard I Morimoto. Cell 2013
Patricija van Oosten-Hawle, Robert S Porter, Richard I Morimoto. Cell 2013
40
Identification of a tissue-selective heat shock response regulatory network.
Eric Guisbert, Daniel M Czyz, Klaus Richter, Patrick D McMullen, Richard I Morimoto. PLoS Genet 2013
Eric Guisbert, Daniel M Czyz, Klaus Richter, Patrick D McMullen, Richard I Morimoto. PLoS Genet 2013
40
Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade.
Fabrizio Chiti, Christopher M Dobson. Annu Rev Biochem 2017
Fabrizio Chiti, Christopher M Dobson. Annu Rev Biochem 2017
40
A genetic screening strategy identifies novel regulators of the proteostasis network.
M Catarina Silva, Susan Fox, Monica Beam, Happy Thakkar, Margarida D Amaral, Richard I Morimoto. PLoS Genet 2011
M Catarina Silva, Susan Fox, Monica Beam, Happy Thakkar, Margarida D Amaral, Richard I Morimoto. PLoS Genet 2011
40
Widespread Proteome Remodeling and Aggregation in Aging C. elegans.
Dirk M Walther, Prasad Kasturi, Min Zheng, Stefan Pinkert, Giulia Vecchi, Prajwal Ciryam, Richard I Morimoto, Christopher M Dobson, Michele Vendruscolo, Matthias Mann,[...]. Cell 2015
Dirk M Walther, Prasad Kasturi, Min Zheng, Stefan Pinkert, Giulia Vecchi, Prajwal Ciryam, Richard I Morimoto, Christopher M Dobson, Michele Vendruscolo, Matthias Mann,[...]. Cell 2015
40
Repression of the Heat Shock Response Is a Programmed Event at the Onset of Reproduction.
Johnathan Labbadia, Richard I Morimoto. Mol Cell 2015
Johnathan Labbadia, Richard I Morimoto. Mol Cell 2015
40
Disease-associated prion protein oligomers inhibit the 26S proteasome.
Mark Kristiansen, Pelagia Deriziotis, Derek E Dimcheff, Graham S Jackson, Huib Ovaa, Heike Naumann, Anthony R Clarke, Fijs W B van Leeuwen, Victoria Menéndez-Benito, Nico P Dantuma,[...]. Mol Cell 2007
Mark Kristiansen, Pelagia Deriziotis, Derek E Dimcheff, Graham S Jackson, Huib Ovaa, Heike Naumann, Anthony R Clarke, Fijs W B van Leeuwen, Victoria Menéndez-Benito, Nico P Dantuma,[...]. Mol Cell 2007
20
Proteasome inhibition and Parkinson's disease modeling.
Jordi Bové, Chun Zhou, Vernice Jackson-Lewis, Julie Taylor, Yaping Chu, Hardy J Rideout, Du-Chu Wu, Jeffrey H Kordower, Leonard Petrucelli, Serge Przedborski. Ann Neurol 2006
Jordi Bové, Chun Zhou, Vernice Jackson-Lewis, Julie Taylor, Yaping Chu, Hardy J Rideout, Du-Chu Wu, Jeffrey H Kordower, Leonard Petrucelli, Serge Przedborski. Ann Neurol 2006
20
Polyglutamine-Expanded Huntingtin Exacerbates Age-Related Disruption of Nuclear Integrity and Nucleocytoplasmic Transport.
Fatima Gasset-Rosa, Carlos Chillon-Marinas, Alexander Goginashvili, Ranjit Singh Atwal, Jonathan W Artates, Ricardos Tabet, Vanessa C Wheeler, Anne G Bang, Don W Cleveland, Clotilde Lagier-Tourenne. Neuron 2017
Fatima Gasset-Rosa, Carlos Chillon-Marinas, Alexander Goginashvili, Ranjit Singh Atwal, Jonathan W Artates, Ricardos Tabet, Vanessa C Wheeler, Anne G Bang, Don W Cleveland, Clotilde Lagier-Tourenne. Neuron 2017
20
Cortical circuit alterations precede motor impairments in Huntington's disease mice.
Johanna Burgold, Elena Katharina Schulz-Trieglaff, Kerstin Voelkl, Sara Gutiérrez-Ángel, Jakob Maximilian Bader, Fabian Hosp, Matthias Mann, Thomas Arzberger, Rüdiger Klein, Sabine Liebscher,[...]. Sci Rep 2019
Johanna Burgold, Elena Katharina Schulz-Trieglaff, Kerstin Voelkl, Sara Gutiérrez-Ángel, Jakob Maximilian Bader, Fabian Hosp, Matthias Mann, Thomas Arzberger, Rüdiger Klein, Sabine Liebscher,[...]. Sci Rep 2019
20
Small heat shock proteins protect against alpha-synuclein-induced toxicity and aggregation.
Tiago Fleming Outeiro, Jochen Klucken, Katherine E Strathearn, Fang Liu, Paul Nguyen, Jean-Christophe Rochet, Bradley T Hyman, Pamela J McLean. Biochem Biophys Res Commun 2006
Tiago Fleming Outeiro, Jochen Klucken, Katherine E Strathearn, Fang Liu, Paul Nguyen, Jean-Christophe Rochet, Bradley T Hyman, Pamela J McLean. Biochem Biophys Res Commun 2006
20
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
20
Functional alterations of the ubiquitin-proteasome system in motor neurons of a mouse model of familial amyotrophic lateral sclerosis.
Cristina Cheroni, Marianna Marino, Massimo Tortarolo, Pietro Veglianese, Silvia De Biasi, Elena Fontana, Laura Vitellaro Zuccarello, Christa J Maynard, Nico P Dantuma, Caterina Bendotti. Hum Mol Genet 2009
Cristina Cheroni, Marianna Marino, Massimo Tortarolo, Pietro Veglianese, Silvia De Biasi, Elena Fontana, Laura Vitellaro Zuccarello, Christa J Maynard, Nico P Dantuma, Caterina Bendotti. Hum Mol Genet 2009
20
Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease.
A Yamamoto, J J Lucas, R Hen. Cell 2000
A Yamamoto, J J Lucas, R Hen. Cell 2000
20
Embryonic Mutant Huntingtin Aggregate Formation in Mouse Models of Huntington's Disease.
Alexander P Osmand, Terry Jo Bichell, Aaron B Bowman, Gillian P Bates. J Huntingtons Dis 2016
Alexander P Osmand, Terry Jo Bichell, Aaron B Bowman, Gillian P Bates. J Huntingtons Dis 2016
20
Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila.
Shermali Gunawardena, Lu-Shiun Her, Richard G Brusch, Robert A Laymon, Ingrid R Niesman, Beth Gordesky-Gold, Louis Sintasath, Nancy M Bonini, Lawrence S B Goldstein. Neuron 2003
Shermali Gunawardena, Lu-Shiun Her, Richard G Brusch, Robert A Laymon, Ingrid R Niesman, Beth Gordesky-Gold, Louis Sintasath, Nancy M Bonini, Lawrence S B Goldstein. Neuron 2003
20
Neural differentiation and the attenuated heat shock response.
Jingxian Yang, Jay Oza, Kristen Bridges, Kuang Yu Chen, Alice Y-C Liu. Brain Res 2008
Jingxian Yang, Jay Oza, Kristen Bridges, Kuang Yu Chen, Alice Y-C Liu. Brain Res 2008
20
A DNAJB chaperone subfamily with HDAC-dependent activities suppresses toxic protein aggregation.
Jurre Hageman, Maria A Rujano, Maria A W H van Waarde, Vaishali Kakkar, Ron P Dirks, Natalia Govorukhina, Henderika M J Oosterveld-Hut, Nicolette H Lubsen, Harm H Kampinga. Mol Cell 2010
Jurre Hageman, Maria A Rujano, Maria A W H van Waarde, Vaishali Kakkar, Ron P Dirks, Natalia Govorukhina, Henderika M J Oosterveld-Hut, Nicolette H Lubsen, Harm H Kampinga. Mol Cell 2010
20
Overexpression of heat shock protein 70 in R6/2 Huntington's disease mice has only modest effects on disease progression.
Oskar Hansson, Jesper Nylandsted, Roger F Castilho, Marcel Leist, Marja Jäättelä, Patrik Brundin. Brain Res 2003
Oskar Hansson, Jesper Nylandsted, Roger F Castilho, Marcel Leist, Marja Jäättelä, Patrik Brundin. Brain Res 2003
20
Acute polyglutamine expression in inducible mouse model unravels ubiquitin/proteasome system impairment and permanent recovery attributable to aggregate formation.
Zaira Ortega, Miguel Díaz-Hernández, Christa J Maynard, Félix Hernández, Nico P Dantuma, José J Lucas. J Neurosci 2010
Zaira Ortega, Miguel Díaz-Hernández, Christa J Maynard, Félix Hernández, Nico P Dantuma, José J Lucas. J Neurosci 2010
20
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
20
Over-expression of Hsp27 does not influence disease in the mutant SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
Jyothsna Krishnan, Kayleen Vannuvel, Maria Andries, Etienne Waelkens, Wim Robberecht, Ludo Van Den Bosch. J Neurochem 2008
Jyothsna Krishnan, Kayleen Vannuvel, Maria Andries, Etienne Waelkens, Wim Robberecht, Ludo Van Den Bosch. J Neurochem 2008
20
HSPB7 is the most potent polyQ aggregation suppressor within the HSPB family of molecular chaperones.
Michel J Vos, Marianne P Zijlstra, Bart Kanon, Maria A W H van Waarde-Verhagen, Ewout R P Brunt, Hendrika M J Oosterveld-Hut, Serena Carra, Ody C M Sibon, Harm H Kampinga. Hum Mol Genet 2010
Michel J Vos, Marianne P Zijlstra, Bart Kanon, Maria A W H van Waarde-Verhagen, Ewout R P Brunt, Hendrika M J Oosterveld-Hut, Serena Carra, Ody C M Sibon, Harm H Kampinga. Hum Mol Genet 2010
20
Indirect inhibition of 26S proteasome activity in a cellular model of Huntington's disease.
Mark S Hipp, Chetan N Patel, Kirill Bersuker, Brigit E Riley, Stephen E Kaiser, Thomas A Shaler, Michael Brandeis, Ron R Kopito. J Cell Biol 2012
Mark S Hipp, Chetan N Patel, Kirill Bersuker, Brigit E Riley, Stephen E Kaiser, Thomas A Shaler, Michael Brandeis, Ron R Kopito. J Cell Biol 2012
20
Heat shock treatment reduces beta amyloid toxicity in vivo by diminishing oligomers.
Yanjue Wu, Zhiming Cao, William L Klein, Yuan Luo. Neurobiol Aging 2010
Yanjue Wu, Zhiming Cao, William L Klein, Yuan Luo. Neurobiol Aging 2010
20
Distinct proteostasis circuits cooperate in nuclear and cytoplasmic protein quality control.
Rahul S Samant, Christine M Livingston, Emily M Sontag, Judith Frydman. Nature 2018
Rahul S Samant, Christine M Livingston, Emily M Sontag, Judith Frydman. Nature 2018
20
Protective effects of heat shock protein 27 in a model of ALS occur in the early stages of disease progression.
Paul S Sharp, Mohammed T Akbar, Sonia Bouri, Atsushi Senda, Kieran Joshi, Han-Jou Chen, David S Latchman, Dominic J Wells, Jacqueline de Belleroche. Neurobiol Dis 2008
Paul S Sharp, Mohammed T Akbar, Sonia Bouri, Atsushi Senda, Kieran Joshi, Han-Jou Chen, David S Latchman, Dominic J Wells, Jacqueline de Belleroche. Neurobiol Dis 2008
20
Cellular localization and development of neuronal intranuclear inclusions in striatal and cortical neurons in R6/2 transgenic mice.
Christopher A Meade, Yun-Ping Deng, Francesca R Fusco, Nobel Del Mar, Steven Hersch, Dan Goldowitz, Anton Reiner. J Comp Neurol 2002
Christopher A Meade, Yun-Ping Deng, Francesca R Fusco, Nobel Del Mar, Steven Hersch, Dan Goldowitz, Anton Reiner. J Comp Neurol 2002
20
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.