A citation-based method for searching scientific literature

Yasushi Kondo, Joseph W Paul, Sriram Subramaniam, John Kuriyan. Curr Opin Struct Biol 2021
Times Cited: 2







List of co-cited articles
4 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Cryo-EM structure of a dimeric B-Raf:14-3-3 complex reveals asymmetry in the active sites of B-Raf kinases.
Yasushi Kondo, Jana Ognjenović, Saikat Banerjee, Deepti Karandur, Alan Merk, Kayla Kulhanek, Kathryn Wong, Jeroen P Roose, Sriram Subramaniam, John Kuriyan. Science 2019
71
100

Negative regulation of RAF kinase activity by ATP is overcome by 14-3-3-induced dimerization.
Nicholas P D Liau, Timothy J Wendorff, John G Quinn, Micah Steffek, Wilson Phung, Peter Liu, Jia Tang, Flaviyan J Irudayanathan, Saeed Izadi, Andrey S Shaw,[...]. Nat Struct Mol Biol 2020
37
100

Dimerization Induced by C-Terminal 14-3-3 Binding Is Sufficient for BRAF Kinase Activation.
Nicholas P D Liau, Avinashnarayan Venkatanarayan, John G Quinn, Wilson Phung, Shiva Malek, Sarah G Hymowitz, Jawahar Sudhamsu. Biochemistry 2020
14
100

Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes.
Eunyoung Park, Shaun Rawson, Kunhua Li, Byeong-Won Kim, Scott B Ficarro, Gonzalo Gonzalez-Del Pino, Humayun Sharif, Jarrod A Marto, Hyesung Jeon, Michael J Eck. Nature 2019
111
100

A Raf-induced allosteric transition of KSR stimulates phosphorylation of MEK.
Damian F Brennan, Arvin C Dar, Nicholas T Hertz, William C H Chao, Alma L Burlingame, Kevan M Shokat, David Barford. Nature 2011
187
50


Regulation of RAF protein kinases in ERK signalling.
Hugo Lavoie, Marc Therrien. Nat Rev Mol Cell Biol 2015
354
50

A CC-SAM, for coiled coil-sterile α motif, domain targets the scaffold KSR-1 to specific sites in the plasma membrane.
Dorothy Koveal, Natasha Schuh-Nuhfer, Daniel Ritt, Rebecca Page, Deborah K Morrison, Wolfgang Peti. Sci Signal 2012
27
50

The drug-target residence time model: a 10-year retrospective.
Robert A Copeland. Nat Rev Drug Discov 2016
362
50

KSR: a MAPK scaffold of the Ras pathway?
D K Morrison. J Cell Sci 2001
175
50

Deficiency of kinase suppressor of Ras1 prevents oncogenic ras signaling in mice.
José Lozano, Rosie Xing, Zhenzi Cai, Heather L Jensen, Carol Trempus, Willie Mark, Ron Cannon, Richard Kolesnick. Cancer Res 2003
98
50

Signal transduction: hanging on a scaffold.
W R Burack, A S Shaw. Curr Opin Cell Biol 2000
260
50

Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization.
S Stewart, M Sundaram, Y Zhang, J Lee, M Han, K L Guan. Mol Cell Biol 1999
174
50

Crystal structures of MEK1 binary and ternary complexes with nucleotides and inhibitors.
Thierry O Fischmann, Catherine K Smith, Todd W Mayhood, Joseph E Myers, Paul Reichert, Anthony Mannarino, Donna Carr, Hugh Zhu, Jesse Wong, Rong-Sheng Yang,[...]. Biochemistry 2009
125
50

Disruption of CRAF-mediated MEK activation is required for effective MEK inhibition in KRAS mutant tumors.
Piro Lito, Anna Saborowski, Jingyin Yue, Martha Solomon, Eric Joseph, Sunyana Gadal, Michael Saborowski, Edward Kastenhuber, Christof Fellmann, Kazuhiro Ohara,[...]. Cancer Cell 2014
190
50

Functional interrogation of the kinome using nucleotide acyl phosphates.
Matthew P Patricelli, A Katrin Szardenings, Marek Liyanage, Tyzoon K Nomanbhoy, Min Wu, Helge Weissig, Arwin Aban, Doris Chun, Stephen Tanner, John W Kozarich. Biochemistry 2007
309
50


Towards automated crystallographic structure refinement with phenix.refine.
Pavel V Afonine, Ralf W Grosse-Kunstleve, Nathaniel Echols, Jeffrey J Headd, Nigel W Moriarty, Marat Mustyakimov, Thomas C Terwilliger, Alexandre Urzhumtsev, Peter H Zwart, Paul D Adams. Acta Crystallogr D Biol Crystallogr 2012
50

Mutant-selective degradation by BRAF-targeting PROTACs.
Shanique Alabi, Saul Jaime-Figueroa, Zhan Yao, Yijun Gao, John Hines, Kusal T G Samarasinghe, Lea Vogt, Neal Rosen, Craig M Crews. Nat Commun 2021
31
50

Structural basis for the action of the drug trametinib at KSR-bound MEK.
Zaigham M Khan, Alexander M Real, William M Marsiglia, Arthur Chow, Mary E Duffy, Jayasudhan R Yerabolu, Alex P Scopton, Arvin C Dar. Nature 2020
42
50

A structural model of a Ras-Raf signalosome.
Venkatesh P Mysore, Zhi-Wei Zhou, Chiara Ambrogio, Lianbo Li, Jonas N Kapp, Chunya Lu, Qi Wang, Maxwell R Tucker, Jeffrey J Okoro, Gabriela Nagy-Davidescu,[...]. Nat Struct Mol Biol 2021
16
50

Allosteric activation of functionally asymmetric RAF kinase dimers.
Jiancheng Hu, Edward C Stites, Haiyang Yu, Elizabeth A Germino, Hiruy S Meharena, Philip J S Stork, Alexandr P Kornev, Susan S Taylor, Andrey S Shaw. Cell 2013
188
50

C-TAK1 regulates Ras signaling by phosphorylating the MAPK scaffold, KSR1.
J Müller, S Ory, T Copeland, H Piwnica-Worms, D K Morrison. Mol Cell 2001
228
50


KSR stimulates Raf-1 activity in a kinase-independent manner.
N R Michaud, M Therrien, A Cacace, L C Edsall, S Spiegel, G M Rubin, D K Morrison. Proc Natl Acad Sci U S A 1997
139
50

Homozygous KSR1 deletion attenuates morbidity but does not prevent tumor development in a mouse model of RAS-driven pancreatic cancer.
Elizabeth A Germino, Joseph P Miller, Lauri Diehl, Carter J Swanson, Steffen Durinck, Zora Modrusan, Jeffrey H Miner, Andrey S Shaw. PLoS One 2018
2
50

KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation.
Timothy H Tran, Albert H Chan, Lucy C Young, Lakshman Bindu, Chris Neale, Simon Messing, Srisathiyanarayanan Dharmaiah, Troy Taylor, John-Paul Denson, Dominic Esposito,[...]. Nat Commun 2021
45
50

Type II Binders Targeting the "GLR-Out" Conformation of the Pseudokinase STRADα.
Ryan H B Smith, Zaigham M Khan, Peter Man-Un Ung, Alex P Scopton, Lisa Silber, Seshat M Mack, Alexander M Real, Avner Schlessinger, Arvin C Dar. Biochemistry 2021
6
50

Enhanced inhibition of ERK signaling by a novel allosteric MEK inhibitor, CH5126766, that suppresses feedback reactivation of RAF activity.
Nobuya Ishii, Naoki Harada, Eric W Joseph, Kazuhiro Ohara, Takaaki Miura, Hiroshi Sakamoto, Yutaka Matsuda, Yasushi Tomii, Yukako Tachibana-Kondo, Hitoshi Iikura,[...]. Cancer Res 2013
104
50

Mutation that blocks ATP binding creates a pseudokinase stabilizing the scaffolding function of kinase suppressor of Ras, CRAF and BRAF.
Jiancheng Hu, Haiyang Yu, Alexandr P Kornev, Jianping Zhao, Erin L Filbert, Susan S Taylor, Andrey S Shaw. Proc Natl Acad Sci U S A 2011
101
50

KSR modulates signal propagation within the MAPK cascade.
M Therrien, N R Michaud, G M Rubin, D K Morrison. Genes Dev 1996
211
50

The molecular scaffold kinase suppressor of Ras 1 is a modifier of RasV12-induced and replicative senescence.
Robert L Kortum, Heidi J Johnson, Diane L Costanzo, Deanna J Volle, Gina L Razidlo, Angela M Fusello, Andrey S Shaw, Robert E Lewis. Mol Cell Biol 2006
38
50

XDS.
Wolfgang Kabsch. Acta Crystallogr D Biol Crystallogr 2010
50

Functional characterization of a PROTAC directed against BRAF mutant V600E.
Ganna Posternak, Xiaojing Tang, Pierre Maisonneuve, Ting Jin, Hugo Lavoie, Salima Daou, Stephen Orlicky, Theo Goullet de Rugy, Lauren Caldwell, Kin Chan,[...]. Nat Chem Biol 2020
41
50

Mutation of position 52 in ERK2 creates a nonproductive binding mode for adenosine 5'-triphosphate.
M J Robinson, P C Harkins, J Zhang, R Baer, J W Haycock, M H Cobb, E J Goldsmith. Biochemistry 1996
130
50

Discovery of a First-in-Class Mitogen-Activated Protein Kinase Kinase 1/2 Degrader.
Jieli Wei, Jianping Hu, Li Wang, Ling Xie, Margaret S Jin, Xian Chen, Jing Liu, Jian Jin. J Med Chem 2019
28
50

Allosteric MEK inhibitors act on BRAF/MEK complexes to block MEK activation.
Gonzalo L Gonzalez-Del Pino, Kunhua Li, Eunyoung Park, Anna M Schmoker, Byung Hak Ha, Michael J Eck. Proc Natl Acad Sci U S A 2021
8
50

Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF.
Paul T C Wan, Mathew J Garnett, S Mark Roe, Sharlene Lee, Dan Niculescu-Duvaz, Valerie M Good, C Michael Jones, Christopher J Marshall, Caroline J Springer, David Barford,[...]. Cell 2004
50


Targeting Alterations in the RAF-MEK Pathway.
Rona Yaeger, Ryan B Corcoran. Cancer Discov 2019
170
50

In situ kinase profiling reveals functionally relevant properties of native kinases.
Matthew P Patricelli, Tyzoon K Nomanbhoy, Jiangyue Wu, Heidi Brown, David Zhou, Jianming Zhang, Subadhra Jagannathan, Arwin Aban, Eric Okerberg, Chris Herring,[...]. Chem Biol 2011
238
50


Complex formation between RAS and RAF and other protein kinases.
L Van Aelst, M Barr, S Marcus, A Polverino, M Wigler. Proc Natl Acad Sci U S A 1993
577
50

A screen for genes that function downstream of Ras1 during Drosophila eye development.
F D Karim, H C Chang, M Therrien, D A Wassarman, T Laverty, G M Rubin. Genetics 1996
200
50

KSR2 is an essential regulator of AMP kinase, energy expenditure, and insulin sensitivity.
Diane L Costanzo-Garvey, Paul T Pfluger, Michele K Dougherty, Jeffery L Stock, Matthew Boehm, Oleg Chaika, Mario R Fernandez, Kurt Fisher, Robert L Kortum, Eun-Gyoung Hong,[...]. Cell Metab 2009
107
50


Crystal structure of a BRAF kinase domain monomer explains basis for allosteric regulation.
Neroshan Thevakumaran, Hugo Lavoie, David A Critton, Andrew Tebben, Anne Marinier, Frank Sicheri, Marc Therrien. Nat Struct Mol Biol 2015
95
50


Active Ras induces heterodimerization of cRaf and BRaf.
C K Weber, J R Slupsky, H A Kalmes, U R Rapp. Cancer Res 2001
235
50

The protein kinase KSR interacts with 14-3-3 protein and Raf.
H Xing, K Kornfeld, A J Muslin. Curr Biol 1997
150
50


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.