Vivek Garg, Junji Suzuki, Ishan Paranjpe, Tiffany Unsulangi, Liron Boyman, Lorin S Milescu, W Jonathan Lederer, Yuriy Kirichok. Elife 2021
Times Cited: 9
Times Cited: 9
Times Cited
Times Co-cited
Similarity
Structure and mechanism of the mitochondrial Ca2+ uniporter holocomplex.
Minrui Fan, Jinru Zhang, Chen-Wei Tsai, Benjamin J Orlando, Madison Rodriguez, Yan Xu, Maofu Liao, Ming-Feng Tsai, Liang Feng. Nature 2020
Minrui Fan, Jinru Zhang, Chen-Wei Tsai, Benjamin J Orlando, Madison Rodriguez, Yan Xu, Maofu Liao, Ming-Feng Tsai, Liang Feng. Nature 2020
55
Structures reveal gatekeeping of the mitochondrial Ca2+ uniporter by MICU1-MICU2.
Chongyuan Wang, Agata Jacewicz, Bryce D Delgado, Rozbeh Baradaran, Stephen Barstow Long. Elife 2020
Chongyuan Wang, Agata Jacewicz, Bryce D Delgado, Rozbeh Baradaran, Stephen Barstow Long. Elife 2020
55
EMRE is an essential component of the mitochondrial calcium uniporter complex.
Yasemin Sancak, Andrew L Markhard, Toshimori Kitami, Erika Kovács-Bogdán, Kimberli J Kamer, Namrata D Udeshi, Steven A Carr, Dipayan Chaudhuri, David E Clapham, Andrew A Li,[...]. Science 2013
Yasemin Sancak, Andrew L Markhard, Toshimori Kitami, Erika Kovács-Bogdán, Kimberli J Kamer, Namrata D Udeshi, Steven A Carr, Dipayan Chaudhuri, David E Clapham, Andrew A Li,[...]. Science 2013
44
MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2+) uptake that regulates cell survival.
Karthik Mallilankaraman, Patrick Doonan, César Cárdenas, Harish C Chandramoorthy, Marioly Müller, Russell Miller, Nicholas E Hoffman, Rajesh Kumar Gandhirajan, Jordi Molgó, Morris J Birnbaum,[...]. Cell 2012
Karthik Mallilankaraman, Patrick Doonan, César Cárdenas, Harish C Chandramoorthy, Marioly Müller, Russell Miller, Nicholas E Hoffman, Rajesh Kumar Gandhirajan, Jordi Molgó, Morris J Birnbaum,[...]. Cell 2012
44
MICU1 encodes a mitochondrial EF hand protein required for Ca(2+) uptake.
Fabiana Perocchi, Vishal M Gohil, Hany S Girgis, X Robert Bao, Janet E McCombs, Amy E Palmer, Vamsi K Mootha. Nature 2010
Fabiana Perocchi, Vishal M Gohil, Hany S Girgis, X Robert Bao, Janet E McCombs, Amy E Palmer, Vamsi K Mootha. Nature 2010
44
The molecular era of the mitochondrial calcium uniporter.
Kimberli J Kamer, Vamsi K Mootha. Nat Rev Mol Cell Biol 2015
Kimberli J Kamer, Vamsi K Mootha. Nat Rev Mol Cell Biol 2015
44
Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter.
Joshua M Baughman, Fabiana Perocchi, Hany S Girgis, Molly Plovanich, Casey A Belcher-Timme, Yasemin Sancak, X Robert Bao, Laura Strittmatter, Olga Goldberger, Roman L Bogorad,[...]. Nature 2011
Joshua M Baughman, Fabiana Perocchi, Hany S Girgis, Molly Plovanich, Casey A Belcher-Timme, Yasemin Sancak, X Robert Bao, Laura Strittmatter, Olga Goldberger, Roman L Bogorad,[...]. Nature 2011
44
The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter.
Xin Pan, Jie Liu, Tiffany Nguyen, Chengyu Liu, Junhui Sun, Yanjie Teng, Maria M Fergusson, Ilsa I Rovira, Michele Allen, Danielle A Springer,[...]. Nat Cell Biol 2013
Xin Pan, Jie Liu, Tiffany Nguyen, Chengyu Liu, Junhui Sun, Yanjie Teng, Maria M Fergusson, Ilsa I Rovira, Michele Allen, Danielle A Springer,[...]. Nat Cell Biol 2013
33
High-affinity cooperative Ca2+ binding by MICU1-MICU2 serves as an on-off switch for the uniporter.
Kimberli J Kamer, Zenon Grabarek, Vamsi K Mootha. EMBO Rep 2017
Kimberli J Kamer, Zenon Grabarek, Vamsi K Mootha. EMBO Rep 2017
33
Structure of intact human MCU supercomplex with the auxiliary MICU subunits.
Wei Zhuo, Heng Zhou, Runyu Guo, Jingbo Yi, Laixing Zhang, Lei Yu, Yinqiang Sui, Wenwen Zeng, Peiyi Wang, Maojun Yang. Protein Cell 2021
Wei Zhuo, Heng Zhou, Runyu Guo, Jingbo Yi, Laixing Zhang, Lei Yu, Yinqiang Sui, Wenwen Zeng, Peiyi Wang, Maojun Yang. Protein Cell 2021
33
NCLX is an essential component of mitochondrial Na+/Ca2+ exchange.
Raz Palty, William F Silverman, Michal Hershfinkel, Teresa Caporale, Stefano L Sensi, Julia Parnis, Christiane Nolte, Daniel Fishman, Varda Shoshan-Barmatz, Sharon Herrmann,[...]. Proc Natl Acad Sci U S A 2010
Raz Palty, William F Silverman, Michal Hershfinkel, Teresa Caporale, Stefano L Sensi, Julia Parnis, Christiane Nolte, Daniel Fishman, Varda Shoshan-Barmatz, Sharon Herrmann,[...]. Proc Natl Acad Sci U S A 2010
33
MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism.
Karthik Mallilankaraman, César Cárdenas, Patrick J Doonan, Harish C Chandramoorthy, Krishna M Irrinki, Tünde Golenár, György Csordás, Priyanka Madireddi, Jun Yang, Marioly Müller,[...]. Nat Cell Biol 2012
Karthik Mallilankaraman, César Cárdenas, Patrick J Doonan, Harish C Chandramoorthy, Krishna M Irrinki, Tünde Golenár, György Csordás, Priyanka Madireddi, Jun Yang, Marioly Müller,[...]. Nat Cell Biol 2012
33
Rearrangement of MICU1 multimers for activation of MCU is solely controlled by cytosolic Ca(2.).
Markus Waldeck-Weiermair, Roland Malli, Warisara Parichatikanond, Benjamin Gottschalk, Corina T Madreiter-Sokolowski, Christiane Klec, Rene Rost, Wolfgang F Graier. Sci Rep 2015
Markus Waldeck-Weiermair, Roland Malli, Warisara Parichatikanond, Benjamin Gottschalk, Corina T Madreiter-Sokolowski, Christiane Klec, Rene Rost, Wolfgang F Graier. Sci Rep 2015
33
PRMT1-mediated methylation of MICU1 determines the UCP2/3 dependency of mitochondrial Ca(2+) uptake in immortalized cells.
Corina T Madreiter-Sokolowski, Christiane Klec, Warisara Parichatikanond, Sarah Stryeck, Benjamin Gottschalk, Sergio Pulido, Rene Rost, Emrah Eroglu, Nicole A Hofmann, Alexander I Bondarenko,[...]. Nat Commun 2016
Corina T Madreiter-Sokolowski, Christiane Klec, Warisara Parichatikanond, Sarah Stryeck, Benjamin Gottschalk, Sergio Pulido, Rene Rost, Emrah Eroglu, Nicole A Hofmann, Alexander I Bondarenko,[...]. Nat Commun 2016
33
MICU1 regulation of mitochondrial Ca(2+) uptake dictates survival and tissue regeneration.
Anil Noronha Antony, Melanie Paillard, Cynthia Moffat, Egle Juskeviciute, Jason Correnti, Brad Bolon, Emanuel Rubin, György Csordás, Erin L Seifert, Jan B Hoek,[...]. Nat Commun 2016
Anil Noronha Antony, Melanie Paillard, Cynthia Moffat, Egle Juskeviciute, Jason Correnti, Brad Bolon, Emanuel Rubin, György Csordás, Erin L Seifert, Jan B Hoek,[...]. Nat Commun 2016
33
OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion.
Christian Frezza, Sara Cipolat, Olga Martins de Brito, Massimo Micaroni, Galina V Beznoussenko, Tomasz Rudka, Davide Bartoli, Roman S Polishuck, Nika N Danial, Bart De Strooper,[...]. Cell 2006
Christian Frezza, Sara Cipolat, Olga Martins de Brito, Massimo Micaroni, Galina V Beznoussenko, Tomasz Rudka, Davide Bartoli, Roman S Polishuck, Nika N Danial, Bart De Strooper,[...]. Cell 2006
33
MICU3 is a tissue-specific enhancer of mitochondrial calcium uptake.
Maria Patron, Veronica Granatiero, Javier Espino, Rosario Rizzuto, Diego De Stefani. Cell Death Differ 2019
Maria Patron, Veronica Granatiero, Javier Espino, Rosario Rizzuto, Diego De Stefani. Cell Death Differ 2019
22
The versatility and universality of calcium signalling.
M J Berridge, P Lipp, M D Bootman. Nat Rev Mol Cell Biol 2000
M J Berridge, P Lipp, M D Bootman. Nat Rev Mol Cell Biol 2000
22
Akt-mediated phosphorylation of MICU1 regulates mitochondrial Ca2+ levels and tumor growth.
Saverio Marchi, Mariangela Corricelli, Alessio Branchini, Veronica Angela Maria Vitto, Sonia Missiroli, Giampaolo Morciano, Mariasole Perrone, Mattia Ferrarese, Carlotta Giorgi, Mirko Pinotti,[...]. EMBO J 2019
Saverio Marchi, Mariangela Corricelli, Alessio Branchini, Veronica Angela Maria Vitto, Sonia Missiroli, Giampaolo Morciano, Mariasole Perrone, Mattia Ferrarese, Carlotta Giorgi, Mirko Pinotti,[...]. EMBO J 2019
22
CCDC90A (MCUR1) is a cytochrome c oxidase assembly factor and not a regulator of the mitochondrial calcium uniporter.
Vincent Paupe, Julien Prudent, Emmanuel P Dassa, Olga Zurita Rendon, Eric A Shoubridge. Cell Metab 2015
Vincent Paupe, Julien Prudent, Emmanuel P Dassa, Olga Zurita Rendon, Eric A Shoubridge. Cell Metab 2015
22
Structure and function of the mitochondrial calcium uniporter complex.
Diego De Stefani, Maria Patron, Rosario Rizzuto. Biochim Biophys Acta 2015
Diego De Stefani, Maria Patron, Rosario Rizzuto. Biochim Biophys Acta 2015
22
MAM (mitochondria-associated membranes) in mammalian cells: lipids and beyond.
Jean E Vance. Biochim Biophys Acta 2014
Jean E Vance. Biochim Biophys Acta 2014
22
Structure of the MICU1-MICU2 heterodimer provides insights into the gatekeeping threshold shift.
Jongseo Park, Youngjin Lee, Taein Park, Jung Youn Kang, Sang A Mun, Minwoo Jin, Jihyeong Yang, Soo Hyun Eom. IUCrJ 2020
Jongseo Park, Youngjin Lee, Taein Park, Jung Youn Kang, Sang A Mun, Minwoo Jin, Jihyeong Yang, Soo Hyun Eom. IUCrJ 2020
22
Molecular regulation of MCU: Implications in physiology and disease.
Neeharika Nemani, Santhanam Shanmughapriya, Muniswamy Madesh. Cell Calcium 2018
Neeharika Nemani, Santhanam Shanmughapriya, Muniswamy Madesh. Cell Calcium 2018
22
Mitochondrial permeability transition pore: sensitivity to opening and mechanistic dependence on substrate availability.
Thomas Briston, Malcolm Roberts, Sian Lewis, Ben Powney, James M Staddon, Gyorgy Szabadkai, Michael R Duchen. Sci Rep 2017
Thomas Briston, Malcolm Roberts, Sian Lewis, Ben Powney, James M Staddon, Gyorgy Szabadkai, Michael R Duchen. Sci Rep 2017
22
Microdomains with high Ca2+ close to IP3-sensitive channels that are sensed by neighboring mitochondria.
R Rizzuto, M Brini, M Murgia, T Pozzan. Science 1993
R Rizzuto, M Brini, M Murgia, T Pozzan. Science 1993
22
Uncoupling proteins 2 and 3 are fundamental for mitochondrial Ca2+ uniport.
Michael Trenker, Roland Malli, Ismene Fertschai, Sanja Levak-Frank, Wolfgang F Graier. Nat Cell Biol 2007
Michael Trenker, Roland Malli, Ismene Fertschai, Sanja Levak-Frank, Wolfgang F Graier. Nat Cell Biol 2007
22
MICU1 Interacts with the D-Ring of the MCU Pore to Control Its Ca2+ Flux and Sensitivity to Ru360.
Melanie Paillard, György Csordás, Kai-Ting Huang, Peter Várnai, Suresh K Joseph, György Hajnóczky. Mol Cell 2018
Melanie Paillard, György Csordás, Kai-Ting Huang, Peter Várnai, Suresh K Joseph, György Hajnóczky. Mol Cell 2018
22
Dual functions of a small regulatory subunit in the mitochondrial calcium uniporter complex.
Ming-Feng Tsai, Charles B Phillips, Matthew Ranaghan, Chen-Wei Tsai, Yujiao Wu, Carole Willliams, Christopher Miller. Elife 2016
Ming-Feng Tsai, Charles B Phillips, Matthew Ranaghan, Chen-Wei Tsai, Yujiao Wu, Carole Willliams, Christopher Miller. Elife 2016
22
MCUB Regulates the Molecular Composition of the Mitochondrial Calcium Uniporter Channel to Limit Mitochondrial Calcium Overload During Stress.
Jonathan P Lambert, Timothy S Luongo, Dhanendra Tomar, Pooja Jadiya, Erhe Gao, Xueqian Zhang, Anna Maria Lucchese, Devin W Kolmetzky, Neil S Shah, John W Elrod. Circulation 2019
Jonathan P Lambert, Timothy S Luongo, Dhanendra Tomar, Pooja Jadiya, Erhe Gao, Xueqian Zhang, Anna Maria Lucchese, Devin W Kolmetzky, Neil S Shah, John W Elrod. Circulation 2019
22
Mitochondrial calcium signalling and cell death: approaches for assessing the role of mitochondrial Ca2+ uptake in apoptosis.
György Hajnóczky, György Csordás, Sudipto Das, Cecilia Garcia-Perez, Masao Saotome, Soumya Sinha Roy, Muqing Yi. Cell Calcium 2006
György Hajnóczky, György Csordás, Sudipto Das, Cecilia Garcia-Perez, Masao Saotome, Soumya Sinha Roy, Muqing Yi. Cell Calcium 2006
22
MCUR1 Is a Scaffold Factor for the MCU Complex Function and Promotes Mitochondrial Bioenergetics.
Dhanendra Tomar, Zhiwei Dong, Santhanam Shanmughapriya, Diana A Koch, Toby Thomas, Nicholas E Hoffman, Shrishiv A Timbalia, Samuel J Goldman, Sarah L Breves, Daniel P Corbally,[...]. Cell Rep 2016
Dhanendra Tomar, Zhiwei Dong, Santhanam Shanmughapriya, Diana A Koch, Toby Thomas, Nicholas E Hoffman, Shrishiv A Timbalia, Samuel J Goldman, Sarah L Breves, Daniel P Corbally,[...]. Cell Rep 2016
22
A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter.
Diego De Stefani, Anna Raffaello, Enrico Teardo, Ildikò Szabò, Rosario Rizzuto. Nature 2011
Diego De Stefani, Anna Raffaello, Enrico Teardo, Ildikò Szabò, Rosario Rizzuto. Nature 2011
22
The mitochondrial calcium uniporter is a multimer that can include a dominant-negative pore-forming subunit.
Anna Raffaello, Diego De Stefani, Davide Sabbadin, Enrico Teardo, Giulia Merli, Anne Picard, Vanessa Checchetto, Stefano Moro, Ildikò Szabò, Rosario Rizzuto. EMBO J 2013
Anna Raffaello, Diego De Stefani, Davide Sabbadin, Enrico Teardo, Giulia Merli, Anne Picard, Vanessa Checchetto, Stefano Moro, Ildikò Szabò, Rosario Rizzuto. EMBO J 2013
22
A MICU1 Splice Variant Confers High Sensitivity to the Mitochondrial Ca2+ Uptake Machinery of Skeletal Muscle.
Denis Vecellio Reane, Francesca Vallese, Vanessa Checchetto, Laura Acquasaliente, Gaia Butera, Vincenzo De Filippis, Ildikò Szabò, Giuseppe Zanotti, Rosario Rizzuto, Anna Raffaello. Mol Cell 2016
Denis Vecellio Reane, Francesca Vallese, Vanessa Checchetto, Laura Acquasaliente, Gaia Butera, Vincenzo De Filippis, Ildikò Szabò, Giuseppe Zanotti, Rosario Rizzuto, Anna Raffaello. Mol Cell 2016
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Tissue-Specific Mitochondrial Decoding of Cytoplasmic Ca2+ Signals Is Controlled by the Stoichiometry of MICU1/2 and MCU.
Melanie Paillard, György Csordás, Gergö Szanda, Tünde Golenár, Valentina Debattisti, Adam Bartok, Nadan Wang, Cynthia Moffat, Erin L Seifert, András Spät,[...]. Cell Rep 2017
Melanie Paillard, György Csordás, Gergö Szanda, Tünde Golenár, Valentina Debattisti, Adam Bartok, Nadan Wang, Cynthia Moffat, Erin L Seifert, András Spät,[...]. Cell Rep 2017
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Ca2+ shuttling between endoplasmic reticulum and mitochondria underlying Ca2+ oscillations.
Kiyoaki Ishii, Kenzo Hirose, Masamitsu Iino. EMBO Rep 2006
Kiyoaki Ishii, Kenzo Hirose, Masamitsu Iino. EMBO Rep 2006
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SLC25A23 augments mitochondrial Ca²⁺ uptake, interacts with MCU, and induces oxidative stress-mediated cell death.
Nicholas E Hoffman, Harish C Chandramoorthy, Santhanam Shanmughapriya, Xueqian Q Zhang, Sandhya Vallem, Patrick J Doonan, Karthik Malliankaraman, Shuchi Guo, Sudarsan Rajan, John W Elrod,[...]. Mol Biol Cell 2014
Nicholas E Hoffman, Harish C Chandramoorthy, Santhanam Shanmughapriya, Xueqian Q Zhang, Sandhya Vallem, Patrick J Doonan, Karthik Malliankaraman, Shuchi Guo, Sudarsan Rajan, John W Elrod,[...]. Mol Biol Cell 2014
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The mitochondrial calcium uniporter is a highly selective ion channel.
Yuriy Kirichok, Grigory Krapivinsky, David E Clapham. Nature 2004
Yuriy Kirichok, Grigory Krapivinsky, David E Clapham. Nature 2004
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MICU2, a paralog of MICU1, resides within the mitochondrial uniporter complex to regulate calcium handling.
Molly Plovanich, Roman L Bogorad, Yasemin Sancak, Kimberli J Kamer, Laura Strittmatter, Andrew A Li, Hany S Girgis, Satya Kuchimanchi, Jack De Groot, Lauren Speciner,[...]. PLoS One 2013
Molly Plovanich, Roman L Bogorad, Yasemin Sancak, Kimberli J Kamer, Laura Strittmatter, Andrew A Li, Hany S Girgis, Satya Kuchimanchi, Jack De Groot, Lauren Speciner,[...]. PLoS One 2013
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The contribution of uncoupling protein 2 to mitochondrial Ca2+ homeostasis in health and disease - A short revisit.
Zhanat Koshenov, Furkan E Oflaz, Martin Hirtl, Olaf A Bachkoenig, Rene Rost, Karin Osibow, Benjamin Gottschalk, Corina T Madreiter-Sokolowski, Markus Waldeck-Weiermair, Roland Malli,[...]. Mitochondrion 2020
Zhanat Koshenov, Furkan E Oflaz, Martin Hirtl, Olaf A Bachkoenig, Rene Rost, Karin Osibow, Benjamin Gottschalk, Corina T Madreiter-Sokolowski, Markus Waldeck-Weiermair, Roland Malli,[...]. Mitochondrion 2020
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Mitochondrial Ca2+ uptake 1 (MICU1) and mitochondrial ca2+ uniporter (MCU) contribute to metabolism-secretion coupling in clonal pancreatic β-cells.
Muhammad Rizwan Alam, Lukas N Groschner, Warisara Parichatikanond, Liang Kuo, Alexander I Bondarenko, Rene Rost, Markus Waldeck-Weiermair, Roland Malli, Wolfgang F Graier. J Biol Chem 2012
Muhammad Rizwan Alam, Lukas N Groschner, Warisara Parichatikanond, Liang Kuo, Alexander I Bondarenko, Rene Rost, Markus Waldeck-Weiermair, Roland Malli, Wolfgang F Graier. J Biol Chem 2012
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MICU1 and MICU2 play nonredundant roles in the regulation of the mitochondrial calcium uniporter.
Kimberli J Kamer, Vamsi K Mootha. EMBO Rep 2014
Kimberli J Kamer, Vamsi K Mootha. EMBO Rep 2014
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X-ray and cryo-EM structures of the mitochondrial calcium uniporter.
Chao Fan, Minrui Fan, Benjamin J Orlando, Nathan M Fastman, Jinru Zhang, Yan Xu, Melissa G Chambers, Xiaofang Xu, Kay Perry, Maofu Liao,[...]. Nature 2018
Chao Fan, Minrui Fan, Benjamin J Orlando, Nathan M Fastman, Jinru Zhang, Yan Xu, Melissa G Chambers, Xiaofang Xu, Kay Perry, Maofu Liao,[...]. Nature 2018
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Structural Mechanism of EMRE-Dependent Gating of the Human Mitochondrial Calcium Uniporter.
Yan Wang, Nam X Nguyen, Ji She, Weizhong Zeng, Yi Yang, Xiao-Chen Bai, Youxing Jiang. Cell 2019
Yan Wang, Nam X Nguyen, Ji She, Weizhong Zeng, Yi Yang, Xiao-Chen Bai, Youxing Jiang. Cell 2019
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MICU1 controls both the threshold and cooperative activation of the mitochondrial Ca²⁺ uniporter.
György Csordás, Tünde Golenár, Erin L Seifert, Kimberli J Kamer, Yasemin Sancak, Fabiana Perocchi, Cynthia Moffat, David Weaver, Sergio de la Fuente Perez, Roman Bogorad,[...]. Cell Metab 2013
György Csordás, Tünde Golenár, Erin L Seifert, Kimberli J Kamer, Yasemin Sancak, Fabiana Perocchi, Cynthia Moffat, David Weaver, Sergio de la Fuente Perez, Roman Bogorad,[...]. Cell Metab 2013
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Mitochondrial Ca2+ Uniporter Is a Mitochondrial Luminal Redox Sensor that Augments MCU Channel Activity.
Zhiwei Dong, Santhanam Shanmughapriya, Dhanendra Tomar, Naveed Siddiqui, Solomon Lynch, Neeharika Nemani, Sarah L Breves, Xueqian Zhang, Aparna Tripathi, Palaniappan Palaniappan,[...]. Mol Cell 2017
Zhiwei Dong, Santhanam Shanmughapriya, Dhanendra Tomar, Naveed Siddiqui, Solomon Lynch, Neeharika Nemani, Sarah L Breves, Xueqian Zhang, Aparna Tripathi, Palaniappan Palaniappan,[...]. Mol Cell 2017
22
Calcium Signaling and Reactive Oxygen Species in Mitochondria.
Edoardo Bertero, Christoph Maack. Circ Res 2018
Edoardo Bertero, Christoph Maack. Circ Res 2018
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.