Steven J Middleton, Jimena Perez-Sanchez, John M Dawes. J Anat 2022
Times Cited: 3
Times Cited: 3
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Molecular identification of rapidly adapting mechanoreceptors and their developmental dependence on ret signaling.
Wenqin Luo, Hideki Enomoto, Frank L Rice, Jeffrey Milbrandt, David D Ginty. Neuron 2009
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Tiling and somatotopic alignment of mammalian low-threshold mechanoreceptors.
Emily D Kuehn, Shan Meltzer, Victoria E Abraira, Cheng-Ying Ho, David D Ginty. Proc Natl Acad Sci U S A 2019
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The structure and organization of lanceolate mechanosensory complexes at mouse hair follicles.
Lishi Li, David D Ginty. Elife 2014
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The functional organization of cutaneous low-threshold mechanosensory neurons.
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Meissner corpuscles and their spatially intermingled afferents underlie gentle touch perception.
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The cellular and molecular basis of direction selectivity of Aδ-LTMRs.
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Lumbar sympathectomy failed to reverse mechanical allodynia- and hyperalgesia-like behavior in rats with L5 spinal nerve injury.
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Sprouting of A beta fibers into lamina II of the rat dorsal horn in peripheral neuropathy.
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Ablation of TrpV1 neurons reveals their selective role in thermal pain sensation.
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Chronic neuronal activation increases dynamic microtubules to enhance functional axon regeneration after dorsal root crush injury.
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A Functional Topographic Map for Spinal Sensorimotor Reflexes.
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Presynaptic GABAergic inhibition regulated by BDNF contributes to neuropathic pain induction.
Jeremy Tsung-chieh Chen, Da Guo, Dario Campanelli, Flavia Frattini, Florian Mayer, Luming Zhou, Rohini Kuner, Paul A Heppenstall, Marlies Knipper, Jing Hu. Nat Commun 2014
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Dorsal root potentials and dorsal root reflexes: a double-edged sword.
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Dorsal horn neurons presynaptic to lamina I spinoparabrachial neurons revealed by transynaptic labeling.
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The Role of BDNF in Peripheral Nerve Regeneration: Activity-Dependent Treatments and Val66Met.
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Silencing the Kir4.1 potassium channel subunit in satellite glial cells of the rat trigeminal ganglion results in pain-like behavior in the absence of nerve injury.
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Control of mechanical pain hypersensitivity in mice through ligand-targeted photoablation of TrkB-positive sensory neurons.
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Increased excitability and spontaneous activity of rat sensory neurons following in vitro stimulation of sympathetic fiber sprouts in the isolated dorsal root ganglion.
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A simulation of action potentials in synaptic boutons during presynaptic inhibition.
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The Role of Voltage-Gated Sodium Channels in Pain Signaling.
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Pain without nociceptors? Nav1.7-independent pain mechanisms.
Michael S Minett, Sarah Falk, Sonia Santana-Varela, Yury D Bogdanov, Mohammed A Nassar, Anne-Marie Heegaard, John N Wood. Cell Rep 2014
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Deconstructing the neuropathic pain phenotype to reveal neural mechanisms.
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Branching points of primary afferent fibers are vital for the modulation of fiber excitability by epidural DC polarization and by GABA in the rat spinal cord.
Yaqing Li, Krishnapriya Hari, Ana M Lucas-Osma, Keith K Fenrich, David J Bennett, Ingela Hammar, Elzbieta Jankowska. J Neurophysiol 2020
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Sensory afferents regenerated into dorsal columns after spinal cord injury remain in a chronic pathophysiological state.
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Temperature-dependent double spikes in C-nociceptors of neuropathic pain patients.
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DC-Evoked Modulation of Excitability of Myelinated Nerve Fibers and Their Terminal Branches; Differences in Sustained Effects of DC.
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Morton's neuroma: review of anatomy, pathomechanism, and imaging.
M S Mak, R Chowdhury, R Johnson. Clin Radiol 2021
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The neurotrophins NGF and NT-3 reduce sensory neuronal loss in adult rat after peripheral nerve lesion.
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Spike propagation through the dorsal root ganglia in an unmyelinated sensory neuron: a modeling study.
Danielle Sundt, Nikita Gamper, David B Jaffe. J Neurophysiol 2015
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Computation of action potential propagation and presynaptic bouton activation in terminal arborizations of different geometries.
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Transient loss of terminals from non-peptidergic nociceptive fibers in the substantia gelatinosa of spinal cord following chronic constriction injury of the sciatic nerve.
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The specialized junctions between Merkel cell and neurite: an electron microscopic study.
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Normal and abnormal coding of somatosensory stimuli causing pain.
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Small fibre impairment predicts neuropathic pain in Guillain-Barré syndrome.
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Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors.
Rebecca P Seal, Xidao Wang, Yun Guan, Srinivasa N Raja, C Jeffery Woodbury, Allan I Basbaum, Robert H Edwards. Nature 2009
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Homozygous mutation in the Neurofascin gene affecting the glial isoform of Neurofascin causes severe neurodevelopment disorder with hypotonia, amimia and areflexia.
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Surgical interventions for the treatment of painful neuroma: a comparative meta-analysis.
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Aberrant Axo-Axonic Synaptic Reorganization in the Phosphorylated L1-CAM/Calcium Channel Subunit α2δ-1-Containing Central Terminals of Injured c-Fibers in the Spinal Cord of a Neuropathic Pain Model.
Hiroki Yamanaka, Masamichi Okubo, Kimiko Kobayashi, Koichi Noguchi. eNeuro 2021
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Primary sensory neurons and satellite cells after peripheral axotomy in the adult rat: timecourse of cell death and elimination.
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Neuromas and postamputation pain.
Nina Stockfleth Buch, Erisela Qerama, Nanna Brix Finnerup, Lone Nikolajsen. Pain 2020
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Demise of nociceptive Schwann cells causes nerve retraction and pain hyperalgesia.
Puneet Rinwa, Laura Calvo-Enrique, Ming-Dong Zhang, Jens Randel Nyengaard, Páll Karlsson, Patrik Ernfors. Pain 2021
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USH2A is a Meissner's corpuscle protein necessary for normal vibration sensing in mice and humans.
Fred Schwaller, Valérie Bégay, Gema García-García, Francisco J Taberner, Rabih Moshourab, Brennan McDonald, Trevor Docter, Johannes Kühnemund, Julia Ojeda-Alonso, Ricardo Paricio-Montesinos,[...]. Nat Neurosci 2021
Fred Schwaller, Valérie Bégay, Gema García-García, Francisco J Taberner, Rabih Moshourab, Brennan McDonald, Trevor Docter, Johannes Kühnemund, Julia Ojeda-Alonso, Ricardo Paricio-Montesinos,[...]. Nat Neurosci 2021
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Using an engineered glutamate-gated chloride channel to silence sensory neurons and treat neuropathic pain at the source.
Greg A Weir, Steven J Middleton, Alex J Clark, Tarun Daniel, Nikita Khovanov, Stephen B McMahon, David L Bennett. Brain 2017
Greg A Weir, Steven J Middleton, Alex J Clark, Tarun Daniel, Nikita Khovanov, Stephen B McMahon, David L Bennett. Brain 2017
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Internodes can nearly double in length with gradual elongation of the adult rat sciatic nerve.
Ichiro Abe, Naoyuki Ochiai, Harumitsu Ichimura, Akihito Tsujino, Jia Sun, Yuki Hara. J Orthop Res 2004
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Failure of action potential propagation in sensory neurons: mechanisms and loss of afferent filtering in C-type units after painful nerve injury.
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Reducing CXCR4-mediated nociceptor hyperexcitability reverses painful diabetic neuropathy.
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Intraepidermal nerve fibers are indicators of small-fiber neuropathy in both diabetic and nondiabetic patients.
Gary L Pittenger, Madhumita Ray, Niculina I Burcus, Patricia McNulty, Baher Basta, Aaron I Vinik. Diabetes Care 2004
Gary L Pittenger, Madhumita Ray, Niculina I Burcus, Patricia McNulty, Baher Basta, Aaron I Vinik. Diabetes Care 2004
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Skin biopsies in myelin-related neuropathies: bringing molecular pathology to the bedside.
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