Qian Cai, Dhasarathan Ganesan. Neurobiol Dis 2022
Times Cited: 10
Times Cited: 10
Times Cited
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Exome sequencing reveals VCP mutations as a cause of familial ALS.
Janel O Johnson, Jessica Mandrioli, Michael Benatar, Yevgeniya Abramzon, Vivianna M Van Deerlin, John Q Trojanowski, J Raphael Gibbs, Maura Brunetti, Susan Gronka, Joanne Wuu,[...]. Neuron 2010
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Mutations of optineurin in amyotrophic lateral sclerosis.
Hirofumi Maruyama, Hiroyuki Morino, Hidefumi Ito, Yuishin Izumi, Hidemasa Kato, Yasuhito Watanabe, Yoshimi Kinoshita, Masaki Kamada, Hiroyuki Nodera, Hidenori Suzuki,[...]. Nature 2010
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
Daniel J Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Steffen Abel, Hagai Abeliovich, Marie H Abildgaard, Yakubu Princely Abudu, Abraham Acevedo-Arozena,[...]. Autophagy 2021
Daniel J Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Steffen Abel, Hagai Abeliovich, Marie H Abildgaard, Yakubu Princely Abudu, Abraham Acevedo-Arozena,[...]. Autophagy 2021
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Microautophagy - distinct molecular mechanisms handle cargoes of many sizes.
Sebastian Schuck. J Cell Sci 2020
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An overview of autophagy: morphology, mechanism, and regulation.
Katherine R Parzych, Daniel J Klionsky. Antioxid Redox Signal 2014
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Autophagy fights disease through cellular self-digestion.
Noboru Mizushima, Beth Levine, Ana Maria Cuervo, Daniel J Klionsky. Nature 2008
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Loss of autophagy in the central nervous system causes neurodegeneration in mice.
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VCP-dependent muscle degeneration is linked to defects in a dynamic tubular lysosomal network in vivo.
Alyssa E Johnson, Huidy Shu, Anna G Hauswirth, Amy Tong, Graeme W Davis. Elife 2015
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Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin.
Atsushi Tanaka, Megan M Cleland, Shan Xu, Derek P Narendra, Der-Fen Suen, Mariusz Karbowski, Richard J Youle. J Cell Biol 2010
Atsushi Tanaka, Megan M Cleland, Shan Xu, Derek P Narendra, Der-Fen Suen, Mariusz Karbowski, Richard J Youle. J Cell Biol 2010
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Selective autophagy: ubiquitin-mediated recognition and beyond.
Claudine Kraft, Matthias Peter, Kay Hofmann. Nat Cell Biol 2010
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A Crucial Role for the Protein Quality Control System in Motor Neuron Diseases.
Riccardo Cristofani, Valeria Crippa, Maria Elena Cicardi, Barbara Tedesco, Veronica Ferrari, Marta Chierichetti, Elena Casarotto, Margherita Piccolella, Elio Messi, Mariarita Galbiati,[...]. Front Aging Neurosci 2020
Riccardo Cristofani, Valeria Crippa, Maria Elena Cicardi, Barbara Tedesco, Veronica Ferrari, Marta Chierichetti, Elena Casarotto, Margherita Piccolella, Elio Messi, Mariarita Galbiati,[...]. Front Aging Neurosci 2020
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TDP-43 mediates degeneration in a novel Drosophila model of disease caused by mutations in VCP/p97.
Gillian P Ritson, Sara K Custer, Brian D Freibaum, Jake B Guinto, Dyanna Geffel, Jennifer Moore, Waixing Tang, Matthew J Winton, Manuela Neumann, John Q Trojanowski,[...]. J Neurosci 2010
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HspB8 and Bag3: a new chaperone complex targeting misfolded proteins to macroautophagy.
Serena Carra, Samuel J Seguin, Jacques Landry. Autophagy 2008
Serena Carra, Samuel J Seguin, Jacques Landry. Autophagy 2008
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A gene network regulating lysosomal biogenesis and function.
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Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins.
Eisuke Itakura, Noboru Mizushima. Autophagy 2010
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Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein.
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VCP/p97 regulates Beclin-1-dependent autophagy initiation.
Sandra M Hill, Lidia Wrobel, Avraham Ashkenazi, Marian Fernandez-Estevez, Keith Tan, Roland W Bürli, David C Rubinsztein. Nat Chem Biol 2021
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Autosomal dominant inclusion body myopathy, Paget disease of bone, and frontotemporal dementia.
Virginia E Kimonis, Giles D J Watts. Alzheimer Dis Assoc Disord 2005
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The nutrient-responsive transcription factor TFE3 promotes autophagy, lysosomal biogenesis, and clearance of cellular debris.
José A Martina, Heba I Diab, Li Lishu, Lim Jeong-A, Simona Patange, Nina Raben, Rosa Puertollano. Sci Signal 2014
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Interactions between autophagy receptors and ubiquitin-like proteins form the molecular basis for selective autophagy.
Vladimir Rogov, Volker Dötsch, Terje Johansen, Vladimir Kirkin. Mol Cell 2014
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Delineating the genetic heterogeneity of ALS using targeted high-throughput sequencing.
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Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
Paola Rusmini, Katia Cortese, Valeria Crippa, Riccardo Cristofani, Maria Elena Cicardi, Veronica Ferrari, Giulia Vezzoli, Barbara Tedesco, Marco Meroni, Elio Messi,[...]. Autophagy 2019
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The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks.
Mayura Meerang, Danilo Ritz, Shreya Paliwal, Zuzana Garajova, Matthias Bosshard, Niels Mailand, Pavel Janscak, Ulrich Hübscher, Hemmo Meyer, Kristijan Ramadan. Nat Cell Biol 2011
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Genotype-phenotype studies of VCP-associated inclusion body myopathy with Paget disease of bone and/or frontotemporal dementia.
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Involvement of valosin-containing protein, an ATPase Co-purified with IkappaBalpha and 26 S proteasome, in ubiquitin-proteasome-mediated degradation of IkappaBalpha.
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Specific inhibition of p97/VCP ATPase and kinetic analysis demonstrate interaction between D1 and D2 ATPase domains.
Tsui-Fen Chou, Stacie L Bulfer, Conrad C Weihl, Kelin Li, Lev G Lis, Michael A Walters, Frank J Schoenen, Henry J Lin, Raymond J Deshaies, Michelle R Arkin. J Mol Biol 2014
Tsui-Fen Chou, Stacie L Bulfer, Conrad C Weihl, Kelin Li, Lev G Lis, Michael A Walters, Frank J Schoenen, Henry J Lin, Raymond J Deshaies, Michelle R Arkin. J Mol Biol 2014
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The p97 ATPase associates with EEA1 to regulate the size of early endosomes.
Harish N Ramanathan, Yihong Ye. Cell Res 2012
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Aggrephagy: selective disposal of protein aggregates by macroautophagy.
Trond Lamark, Terje Johansen. Int J Cell Biol 2012
Trond Lamark, Terje Johansen. Int J Cell Biol 2012
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The crystal structure of murine p97/VCP at 3.6A.
Trevor Huyton, Valerie E Pye, Louise C Briggs, Terence C Flynn, Fabienne Beuron, Hisao Kondo, Jianpeng Ma, Xiaodong Zhang, Paul S Freemont. J Struct Biol 2003
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Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex.
Yun Zhong, Qing Jun Wang, Xianting Li, Ying Yan, Jonathan M Backer, Brian T Chait, Nathaniel Heintz, Zhenyu Yue. Nat Cell Biol 2009
Yun Zhong, Qing Jun Wang, Xianting Li, Ying Yan, Jonathan M Backer, Brian T Chait, Nathaniel Heintz, Zhenyu Yue. Nat Cell Biol 2009
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Cdc48/p97 promotes degradation of aberrant nascent polypeptides bound to the ribosome.
Rati Verma, Robert S Oania, Natalie J Kolawa, Raymond J Deshaies. Elife 2013
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Autophagy in major human diseases.
Daniel J Klionsky, Giulia Petroni, Ravi K Amaravadi, Eric H Baehrecke, Andrea Ballabio, Patricia Boya, José Manuel Bravo-San Pedro, Ken Cadwell, Francesco Cecconi, Augustine M K Choi,[...]. EMBO J 2021
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The AAA-ATPase p97 is essential for outer mitochondrial membrane protein turnover.
Shan Xu, Guihong Peng, Yang Wang, Shengyun Fang, Mariusz Karbowski. Mol Biol Cell 2011
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Tyrosine phosphorylation regulates cell cycle-dependent nuclear localization of Cdc48p.
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The formation of Golgi stacks from vesiculated Golgi membranes requires two distinct fusion events.
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HDAC6-p97/VCP controlled polyubiquitin chain turnover.
Cyril Boyault, Benoit Gilquin, Yu Zhang, Vladimir Rybin, Elspeth Garman, Wolfram Meyer-Klaucke, Patrick Matthias, Christoph W Müller, Saadi Khochbin. EMBO J 2006
Cyril Boyault, Benoit Gilquin, Yu Zhang, Vladimir Rybin, Elspeth Garman, Wolfram Meyer-Klaucke, Patrick Matthias, Christoph W Müller, Saadi Khochbin. EMBO J 2006
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Membrane fusion and the cell cycle: Cdc48p participates in the fusion of ER membranes.
M Latterich, K U Fröhlich, R Schekman. Cell 1995
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Use of a cDNA clone to identify a supposed precursor protein containing valosin.
K J Koller, M J Brownstein. Nature 1987
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The role of the N-domain in the ATPase activity of the mammalian AAA ATPase p97/VCP.
Hajime Niwa, Caroline A Ewens, Chun Tsang, Heidi O Yeung, Xiaodong Zhang, Paul S Freemont. J Biol Chem 2012
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VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD.
Emilie Tresse, Florian A Salomons, Jouni Vesa, Laura C Bott, Virginia Kimonis, Tso-Pang Yao, Nico P Dantuma, J Paul Taylor. Autophagy 2010
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Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L.
Kohichi Matsunaga, Eiji Morita, Tatsuya Saitoh, Shizuo Akira, Nicholas T Ktistakis, Tetsuro Izumi, Takeshi Noda, Tamotsu Yoshimori. J Cell Biol 2010
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Molecular pathways: autophagy in cancer--a matter of timing and context.
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Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease.
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VCP maintains lysosomal homeostasis and TFEB activity in differentiated skeletal muscle.
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Key steps in ERAD of luminal ER proteins reconstituted with purified components.
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VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy.
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VCP/p97 in abnormal protein aggregates, cytoplasmic vacuoles, and cell death, phenotypes relevant to neurodegeneration.
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TFEB links autophagy to lysosomal biogenesis.
Carmine Settembre, Chiara Di Malta, Vinicia Assunta Polito, Moises Garcia Arencibia, Francesco Vetrini, Serkan Erdin, Serpil Uckac Erdin, Tuong Huynh, Diego Medina, Pasqualina Colella,[...]. Science 2011
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HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.