Irfan Khan, Marcel O Schmidt, Bhaskar Kallakury, Sidharth Jain, Shaunt Mehdikhani, Moshe Levi, Margarida Mendonca, William Welch, Anna T Riegel, Christopher S Wilcox, Anton Wellstein. Front Cell Dev Biol 2021
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Vascular endothelial senescence: from mechanisms to pathophysiology.
Jorge D Erusalimsky. J Appl Physiol (1985) 2009
Jorge D Erusalimsky. J Appl Physiol (1985) 2009
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Increased monocytic adhesion by senescence in human umbilical vein endothelial cells.
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SIRT1 promotes proliferation and prevents senescence through targeting LKB1 in primary porcine aortic endothelial cells.
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100
Ionizing radiation promotes the acquisition of a senescence-associated secretory phenotype and impairs angiogenic capacity in cerebromicrovascular endothelial cells: role of increased DNA damage and decreased DNA repair capacity in microvascular radiosensitivity.
Zoltan Ungvari, Andrej Podlutsky, Danuta Sosnowska, Zsuzsanna Tucsek, Peter Toth, Ferenc Deak, Tripti Gautam, Anna Csiszar, William E Sonntag. J Gerontol A Biol Sci Med Sci 2013
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Senescence and apoptosis: dueling or complementary cell fates?
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Decreased B16F10 melanoma growth and impaired vascularization in telomerase-deficient mice with critically short telomeres.
Sonia Franco, Inmaculada Segura, Hans H Riese, María A Blasco. Cancer Res 2002
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Sirt1 modulates premature senescence-like phenotype in human endothelial cells.
Hidetaka Ota, Masahiro Akishita, Masato Eto, Katsuya Iijima, Masao Kaneki, Yasuyoshi Ouchi. J Mol Cell Cardiol 2007
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Telomere uncapping and vascular aging.
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Cellular and molecular biology of aging endothelial cells.
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Endothelial Regeneration of Large Vessels Is a Biphasic Process Driven by Local Cells with Distinct Proliferative Capacities.
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Senescence and senolytics in cardiovascular disease: Promise and potential pitfalls.
W Andrew Owens, Anna Walaszczyk, Ioakim Spyridopoulos, Emily Dookun, Gavin D Richardson. Mech Ageing Dev 2021
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Nitric oxide inhibits vascular smooth muscle cell proliferation and neointimal hyperplasia by increasing the ubiquitination and degradation of UbcH10.
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Endothelial p53 deletion improves angiogenesis and prevents cardiac fibrosis and heart failure induced by pressure overload in mice.
Rajinikanth Gogiraju, Xingbo Xu, Magdalena L Bochenek, Julia H Steinbrecher, Stephan E Lehnart, Philip Wenzel, Michael Kessel, Elisabeth M Zeisberg, Matthias Dobbelstein, Katrin Schäfer. J Am Heart Assoc 2015
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Telomere attrition and accumulation of senescent cells in cultured human endothelial cells.
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Caveolae control the anti-inflammatory phenotype of senescent endothelial cells.
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TNFα-senescence initiates a STAT-dependent positive feedback loop, leading to a sustained interferon signature, DNA damage, and cytokine secretion.
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Endothelial cellular senescence is inhibited by nitric oxide: implications in atherosclerosis associated with menopause and diabetes.
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Mitochondrial Deacetylase Sirt3 Reduces Vascular Dysfunction and Hypertension While Sirt3 Depletion in Essential Hypertension Is Linked to Vascular Inflammation and Oxidative Stress.
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Vascular endothelial cells senescence is associated with NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome activation via reactive oxygen species (ROS)/thioredoxin-interacting protein (TXNIP) pathway.
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Mice deficient in telomerase activity develop hypertension because of an excess of endothelin production.
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Nitric oxide and endothelial cellular senescence.
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Ionizing radiation induces long-term senescence in endothelial cells through mitochondrial respiratory complex II dysfunction and superoxide generation.
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New agents that target senescent cells: the flavone, fisetin, and the BCL-XL inhibitors, A1331852 and A1155463.
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Inflammation and endothelial dysfunction during aging: role of NF-kappaB.
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Glomerular endothelial cell senescence drives age-related kidney disease through PAI-1.
Camille Cohen, Océane Le Goff, Frédéric Soysouvanh, Florence Vasseur, Marine Tanou, Clément Nguyen, Lucile Amrouche, Julien Le Guen, Oriana Saltel-Fulero, Tanguy Meunier,[...]. EMBO Mol Med 2021
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Patterns of Early p21 Dynamics Determine Proliferation-Senescence Cell Fate after Chemotherapy.
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Does fasting plasma insulin increase by age in the general elderly population?
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.