Yasuyuki Kihara, Deepa Jonnalagadda, Yunjiao Zhu, Manisha Ray, Tony Ngo, Carter Palmer, Richard Rivera, Jerold Chun. FASEB J 2022
Times Cited: 5
Times Cited: 5
Times Cited
Times Co-cited
Similarity
FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation.
Ji Woong Choi, Shannon E Gardell, Deron R Herr, Richard Rivera, Chang-Wook Lee, Kyoko Noguchi, Siew Teng Teo, Yun C Yung, Melissa Lu, Grace Kennedy,[...]. Proc Natl Acad Sci U S A 2011
Ji Woong Choi, Shannon E Gardell, Deron R Herr, Richard Rivera, Chang-Wook Lee, Kyoko Noguchi, Siew Teng Teo, Yun C Yung, Melissa Lu, Grace Kennedy,[...]. Proc Natl Acad Sci U S A 2011
60
The selective sphingosine 1-phosphate receptor modulator BAF312 redirects lymphocyte distribution and has species-specific effects on heart rate.
P Gergely, B Nuesslein-Hildesheim, D Guerini, V Brinkmann, M Traebert, C Bruns, S Pan, N S Gray, K Hinterding, N G Cooke,[...]. Br J Pharmacol 2012
P Gergely, B Nuesslein-Hildesheim, D Guerini, V Brinkmann, M Traebert, C Bruns, S Pan, N S Gray, K Hinterding, N G Cooke,[...]. Br J Pharmacol 2012
40
Ponesimod, a selective S1P1 receptor modulator: a potential treatment for multiple sclerosis and other immune-mediated diseases.
Daniele D'Ambrosio, Mark S Freedman, Joerg Prinz. Ther Adv Chronic Dis 2016
Daniele D'Ambrosio, Mark S Freedman, Joerg Prinz. Ther Adv Chronic Dis 2016
40
Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1.
Mehrdad Matloubian, Charles G Lo, Guy Cinamon, Matthew J Lesneski, Ying Xu, Volker Brinkmann, Maria L Allende, Richard L Proia, Jason G Cyster. Nature 2004
Mehrdad Matloubian, Charles G Lo, Guy Cinamon, Matthew J Lesneski, Ying Xu, Volker Brinkmann, Maria L Allende, Richard L Proia, Jason G Cyster. Nature 2004
40
Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study.
Ludwig Kappos, Amit Bar-Or, Bruce A C Cree, Robert J Fox, Gavin Giovannoni, Ralf Gold, Patrick Vermersch, Douglas L Arnold, Sophie Arnould, Tatiana Scherz,[...]. Lancet 2018
Ludwig Kappos, Amit Bar-Or, Bruce A C Cree, Robert J Fox, Gavin Giovannoni, Ralf Gold, Patrick Vermersch, Douglas L Arnold, Sophie Arnould, Tatiana Scherz,[...]. Lancet 2018
40
Sphingosine 1-phosphate Receptor Modulator Therapy for Multiple Sclerosis: Differential Downstream Receptor Signalling and Clinical Profile Effects.
Jerold Chun, Gavin Giovannoni, Samuel F Hunter. Drugs 2021
Jerold Chun, Gavin Giovannoni, Samuel F Hunter. Drugs 2021
40
G-protein-coupled receptor S1P1 acts within endothelial cells to regulate vascular maturation.
Maria L Allende, Tadashi Yamashita, Richard L Proia. Blood 2003
Maria L Allende, Tadashi Yamashita, Richard L Proia. Blood 2003
40
Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation.
Y Liu, R Wada, T Yamashita, Y Mi, C X Deng, J P Hobson, H M Rosenfeldt, V E Nava, S S Chae, M J Lee,[...]. J Clin Invest 2000
Y Liu, R Wada, T Yamashita, Y Mi, C X Deng, J P Hobson, H M Rosenfeldt, V E Nava, S S Chae, M J Lee,[...]. J Clin Invest 2000
40
Deletion of Voltage-Gated Calcium Channels in Astrocytes during Demyelination Reduces Brain Inflammation and Promotes Myelin Regeneration in Mice.
Norma N Zamora, Veronica T Cheli, Diara A Santiago González, Rensheng Wan, Pablo M Paez. J Neurosci 2020
Norma N Zamora, Veronica T Cheli, Diara A Santiago González, Rensheng Wan, Pablo M Paez. J Neurosci 2020
40
Siponimod ameliorates metabolic oligodendrocyte injury via the sphingosine-1 phosphate receptor 5.
Newshan Behrangi, Leo Heinig, Linda Frintrop, Emily Santrau, Jens Kurth, Bernd Krause, Dimitrinka Atanasova, Tim Clarner, Athanassios Fragoulis, Markus Joksch,[...]. Proc Natl Acad Sci U S A 2022
Newshan Behrangi, Leo Heinig, Linda Frintrop, Emily Santrau, Jens Kurth, Bernd Krause, Dimitrinka Atanasova, Tim Clarner, Athanassios Fragoulis, Markus Joksch,[...]. Proc Natl Acad Sci U S A 2022
100
Fingolimod modulates microglial activation to augment markers of remyelination.
Samuel J Jackson, Gavin Giovannoni, David Baker. J Neuroinflammation 2011
Samuel J Jackson, Gavin Giovannoni, David Baker. J Neuroinflammation 2011
40
Increased Remyelination and Proregenerative Microglia Under Siponimod Therapy in Mechanistic Models.
Michael Dietrich, Christina Hecker, Elodie Martin, Dominique Langui, Michael Gliem, Bruno Stankoff, Catherine Lubetzki, Joel Gruchot, Peter Göttle, Andrea Issberner,[...]. Neurol Neuroimmunol Neuroinflamm 2022
Michael Dietrich, Christina Hecker, Elodie Martin, Dominique Langui, Michael Gliem, Bruno Stankoff, Catherine Lubetzki, Joel Gruchot, Peter Göttle, Andrea Issberner,[...]. Neurol Neuroimmunol Neuroinflamm 2022
40
Cellular localization of sphingosine-1-phosphate receptor 1 expression in the human central nervous system.
Hirotake Nishimura, Takashi Akiyama, Isao Irei, Shuji Hamazaki, Yoshito Sadahira. J Histochem Cytochem 2010
Hirotake Nishimura, Takashi Akiyama, Isao Irei, Shuji Hamazaki, Yoshito Sadahira. J Histochem Cytochem 2010
40
Sphingosine 1-phosphate receptor modulators in multiple sclerosis and other conditions.
Marisa P McGinley, Jeffrey A Cohen. Lancet 2021
Marisa P McGinley, Jeffrey A Cohen. Lancet 2021
40
Laquinimod Supports Remyelination in Non-Supportive Environments.
Stella Nyamoya, Julia Steinle, Uta Chrzanowski, Joel Kaye, Christoph Schmitz, Cordian Beyer, Markus Kipp. Cells 2019
Stella Nyamoya, Julia Steinle, Uta Chrzanowski, Joel Kaye, Christoph Schmitz, Cordian Beyer, Markus Kipp. Cells 2019
40
Neurodegeneration Triggers Peripheral Immune Cell Recruitment into the Forebrain.
Miriam Scheld, Bernhard Josef Rüther, René Große-Veldmann, Kim Ohl, Klaus Tenbrock, Daniela Dreymüller, Petra Fallier-Becker, Adib Zendedel, Cordian Beyer, Tim Clarner,[...]. J Neurosci 2016
Miriam Scheld, Bernhard Josef Rüther, René Große-Veldmann, Kim Ohl, Klaus Tenbrock, Daniela Dreymüller, Petra Fallier-Becker, Adib Zendedel, Cordian Beyer, Tim Clarner,[...]. J Neurosci 2016
40
Cuprizone-induced demyelination triggers a CD8-pronounced T cell recruitment.
Hannes Kaddatz, Sarah Joost, Julia Nedelcu, Uta Chrzanowski, Christoph Schmitz, Stefan Gingele, Viktoria Gudi, Martin Stangel, Jiangshan Zhan, Emily Santrau,[...]. Glia 2021
Hannes Kaddatz, Sarah Joost, Julia Nedelcu, Uta Chrzanowski, Christoph Schmitz, Stefan Gingele, Viktoria Gudi, Martin Stangel, Jiangshan Zhan, Emily Santrau,[...]. Glia 2021
40
The dual S1PR1/S1PR5 drug BAF312 (Siponimod) attenuates demyelination in organotypic slice cultures.
Catherine O'Sullivan, Anna Schubart, Anis K Mir, Kumlesh K Dev. J Neuroinflammation 2016
Catherine O'Sullivan, Anna Schubart, Anis K Mir, Kumlesh K Dev. J Neuroinflammation 2016
40
Siponimod (BAF312) prevents synaptic neurodegeneration in experimental multiple sclerosis.
Antonietta Gentile, Alessandra Musella, Silvia Bullitta, Diego Fresegna, Francesca De Vito, Roberta Fantozzi, Eleonora Piras, Francesca Gargano, Giovanna Borsellino, Luca Battistini,[...]. J Neuroinflammation 2016
Antonietta Gentile, Alessandra Musella, Silvia Bullitta, Diego Fresegna, Francesca De Vito, Roberta Fantozzi, Eleonora Piras, Francesca Gargano, Giovanna Borsellino, Luca Battistini,[...]. J Neuroinflammation 2016
40
Activation of sphingosine-1-phosphate receptor S1P5 inhibits oligodendrocyte progenitor migration.
Alexander S Novgorodov, Mazen El-Alwani, Jacek Bielawski, Lina M Obeid, Tatyana I Gudz. FASEB J 2007
Alexander S Novgorodov, Mazen El-Alwani, Jacek Bielawski, Lina M Obeid, Tatyana I Gudz. FASEB J 2007
40
Sphingosine 1-phosphate receptor 1 and 3 are upregulated in multiple sclerosis lesions.
Ruben Van Doorn, Jack Van Horssen, Dennis Verzijl, Maarten Witte, Eric Ronken, Bert Van Het Hof, Kim Lakeman, Christine D Dijkstra, Paul Van Der Valk, Arie Reijerkerk,[...]. Glia 2010
Ruben Van Doorn, Jack Van Horssen, Dennis Verzijl, Maarten Witte, Eric Ronken, Bert Van Het Hof, Kim Lakeman, Christine D Dijkstra, Paul Van Der Valk, Arie Reijerkerk,[...]. Glia 2010
40
Effect of FTY720-phosphate on the expression of inflammation-associated molecules in astrocytes in vitro.
Stefanie Janssen, Caroline Schlegel, Viktoria Gudi, Chittappen Kandiyil Prajeeth, Thomas Skripuletz, Corinna Trebst, Martin Stangel. Mol Med Rep 2015
Stefanie Janssen, Caroline Schlegel, Viktoria Gudi, Chittappen Kandiyil Prajeeth, Thomas Skripuletz, Corinna Trebst, Martin Stangel. Mol Med Rep 2015
40
Cuprizone-induced graded oligodendrocyte vulnerability is regulated by the transcription factor DNA damage-inducible transcript 3.
Felix Fischbach, Julia Nedelcu, Patrizia Leopold, Jiangshan Zhan, Tim Clarner, Lara Nellessen, Christian Beißel, Yasemin van Heuvel, Anand Goswami, Joachim Weis,[...]. Glia 2019
Felix Fischbach, Julia Nedelcu, Patrizia Leopold, Jiangshan Zhan, Tim Clarner, Lara Nellessen, Christian Beißel, Yasemin van Heuvel, Anand Goswami, Joachim Weis,[...]. Glia 2019
40
Neurotoxic reactive astrocytes are induced by activated microglia.
Shane A Liddelow, Kevin A Guttenplan, Laura E Clarke, Frederick C Bennett, Christopher J Bohlen, Lucas Schirmer, Mariko L Bennett, Alexandra E Münch, Won-Suk Chung, Todd C Peterson,[...]. Nature 2017
Shane A Liddelow, Kevin A Guttenplan, Laura E Clarke, Frederick C Bennett, Christopher J Bohlen, Lucas Schirmer, Mariko L Bennett, Alexandra E Münch, Won-Suk Chung, Todd C Peterson,[...]. Nature 2017
20
Fingolimod: direct CNS effects of sphingosine 1-phosphate (S1P) receptor modulation and implications in multiple sclerosis therapy.
Aran Groves, Yasuyuki Kihara, Jerold Chun. J Neurol Sci 2013
Aran Groves, Yasuyuki Kihara, Jerold Chun. J Neurol Sci 2013
20
Cuprizone-induced demyelination in CNP::GFP transgenic mice.
Lucas Silvestroff, Sandra Bartucci, Eduardo Soto, Vittorio Gallo, Juana Pasquini, Paula Franco. J Comp Neurol 2010
Lucas Silvestroff, Sandra Bartucci, Eduardo Soto, Vittorio Gallo, Juana Pasquini, Paula Franco. J Comp Neurol 2010
20
Comprehensive Integration of Single-Cell Data.
Tim Stuart, Andrew Butler, Paul Hoffman, Christoph Hafemeister, Efthymia Papalexi, William M Mauck, Yuhan Hao, Marlon Stoeckius, Peter Smibert, Rahul Satija. Cell 2019
Tim Stuart, Andrew Butler, Paul Hoffman, Christoph Hafemeister, Efthymia Papalexi, William M Mauck, Yuhan Hao, Marlon Stoeckius, Peter Smibert, Rahul Satija. Cell 2019
20
Single-Dose Pharmacokinetics of Ozanimod and its Major Active Metabolites Alone and in Combination with Gemfibrozil, Itraconazole, or Rifampin in Healthy Subjects: A Randomized, Parallel-Group, Open-Label Study.
Jonathan Q Tran, Peijin Zhang, Atalanta Ghosh, Liangang Liu, Mary Syto, Xiaomin Wang, Maria Palmisano. Adv Ther 2020
Jonathan Q Tran, Peijin Zhang, Atalanta Ghosh, Liangang Liu, Mary Syto, Xiaomin Wang, Maria Palmisano. Adv Ther 2020
20
Mechanisms of fingolimod's efficacy and adverse effects in multiple sclerosis.
Jeffrey A Cohen, Jerold Chun. Ann Neurol 2011
Jeffrey A Cohen, Jerold Chun. Ann Neurol 2011
20
Chronic psychosocial stress in mice leads to changes in brain functional connectivity and metabolite levels comparable to human depression.
Joanes Grandjean, Damiano Azzinnari, Aline Seuwen, Hannes Sigrist, Erich Seifritz, Christopher R Pryce, Markus Rudin. Neuroimage 2016
Joanes Grandjean, Damiano Azzinnari, Aline Seuwen, Hannes Sigrist, Erich Seifritz, Christopher R Pryce, Markus Rudin. Neuroimage 2016
20
Early brain pseudoatrophy while on natalizumab therapy is due to white matter volume changes.
Angela Vidal-Jordana, Jaume Sastre-Garriga, Francisco Pérez-Miralles, Carmen Tur, Mar Tintoré, Alejandro Horga, Cristina Auger, Jordi Río, Carlos Nos, Mari C Edo,[...]. Mult Scler 2013
Angela Vidal-Jordana, Jaume Sastre-Garriga, Francisco Pérez-Miralles, Carmen Tur, Mar Tintoré, Alejandro Horga, Cristina Auger, Jordi Río, Carlos Nos, Mari C Edo,[...]. Mult Scler 2013
20
Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists.
Suzanne Mandala, Richard Hajdu, James Bergstrom, Elizabeth Quackenbush, Jenny Xie, James Milligan, Rosemary Thornton, Gan-Ju Shei, Deborah Card, CarolAnn Keohane,[...]. Science 2002
Suzanne Mandala, Richard Hajdu, James Bergstrom, Elizabeth Quackenbush, Jenny Xie, James Milligan, Rosemary Thornton, Gan-Ju Shei, Deborah Card, CarolAnn Keohane,[...]. Science 2002
20
Reactive Astrocytes: Production, Function, and Therapeutic Potential.
Shane A Liddelow, Ben A Barres. Immunity 2017
Shane A Liddelow, Ben A Barres. Immunity 2017
20
Systematic meta-review and quality assessment of the structural brain alterations in schizophrenia.
Alana M Shepherd, Kristin R Laurens, Sandra L Matheson, Vaughan J Carr, Melissa J Green. Neurosci Biobehav Rev 2012
Alana M Shepherd, Kristin R Laurens, Sandra L Matheson, Vaughan J Carr, Melissa J Green. Neurosci Biobehav Rev 2012
20
Mechanism of action of oral fingolimod (FTY720) in multiple sclerosis.
Jerold Chun, Hans-Peter Hartung. Clin Neuropharmacol 2010
Jerold Chun, Hans-Peter Hartung. Clin Neuropharmacol 2010
20
Fingolimod: Lessons Learned and New Opportunities for Treating Multiple Sclerosis and Other Disorders.
Jerold Chun, Yasuyuki Kihara, Deepa Jonnalagadda, Victoria A Blaho. Annu Rev Pharmacol Toxicol 2019
Jerold Chun, Yasuyuki Kihara, Deepa Jonnalagadda, Victoria A Blaho. Annu Rev Pharmacol Toxicol 2019
20
ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks.
Gabriela Bindea, Bernhard Mlecnik, Hubert Hackl, Pornpimol Charoentong, Marie Tosolini, Amos Kirilovsky, Wolf-Herman Fridman, Franck Pagès, Zlatko Trajanoski, Jérôme Galon. Bioinformatics 2009
Gabriela Bindea, Bernhard Mlecnik, Hubert Hackl, Pornpimol Charoentong, Marie Tosolini, Amos Kirilovsky, Wolf-Herman Fridman, Franck Pagès, Zlatko Trajanoski, Jérôme Galon. Bioinformatics 2009
20
A mechanistically novel, first oral therapy for multiple sclerosis: the development of fingolimod (FTY720, Gilenya).
Jerold Chun, Volker Brinkmann. Discov Med 2011
Jerold Chun, Volker Brinkmann. Discov Med 2011
20
Multimodal voxel-based meta-analysis of white matter abnormalities in obsessive-compulsive disorder.
Joaquim Radua, Mar Grau, Odile A van den Heuvel, Michel Thiebaut de Schotten, Dan J Stein, Erick J Canales-Rodríguez, Marco Catani, David Mataix-Cols. Neuropsychopharmacology 2014
Joaquim Radua, Mar Grau, Odile A van den Heuvel, Michel Thiebaut de Schotten, Dan J Stein, Erick J Canales-Rodríguez, Marco Catani, David Mataix-Cols. Neuropsychopharmacology 2014
20
The multifaceted role of astrocytes in regulating myelination.
Hülya Kıray, Susan L Lindsay, Sara Hosseinzadeh, Susan C Barnett. Exp Neurol 2016
Hülya Kıray, Susan L Lindsay, Sara Hosseinzadeh, Susan C Barnett. Exp Neurol 2016
20
Multiple sclerosis: a role for astroglia in active demyelination suggested by class II MHC expression and ultrastructural study.
S C Lee, G R Moore, G Golenwsky, C S Raine. J Neuropathol Exp Neurol 1990
S C Lee, G R Moore, G Golenwsky, C S Raine. J Neuropathol Exp Neurol 1990
20
Are astrocytes central players in the pathophysiology of multiple sclerosis?
Jacques De Keyser, Esther Zeinstra, Elliot Frohman. Arch Neurol 2003
Jacques De Keyser, Esther Zeinstra, Elliot Frohman. Arch Neurol 2003
20
Astrocytes, but not olfactory ensheathing cells or Schwann cells, promote myelination of CNS axons in vitro.
Annette Sorensen, Keith Moffat, Christine Thomson, Susan C Barnett. Glia 2008
Annette Sorensen, Keith Moffat, Christine Thomson, Susan C Barnett. Glia 2008
20
Neural and dopaminergic correlates of fatigue in Parkinson's disease.
Suk Yun Kang, Mirim Bang, Jing Yong Hong, Jungsu Oh, Jae Seung Kim, You Mie Han, Suk Ki Chang, Seun Ah Lee, Uicheul Yoon, Na-Young Shin. J Neural Transm (Vienna) 2020
Suk Yun Kang, Mirim Bang, Jing Yong Hong, Jungsu Oh, Jae Seung Kim, You Mie Han, Suk Ki Chang, Seun Ah Lee, Uicheul Yoon, Na-Young Shin. J Neural Transm (Vienna) 2020
20
Diffusion tensor imaging in autism spectrum disorder: a review.
Brittany G Travers, Nagesh Adluru, Chad Ennis, Do P M Tromp, Dan Destiche, Sam Doran, Erin D Bigler, Nicholas Lange, Janet E Lainhart, Andrew L Alexander. Autism Res 2012
Brittany G Travers, Nagesh Adluru, Chad Ennis, Do P M Tromp, Dan Destiche, Sam Doran, Erin D Bigler, Nicholas Lange, Janet E Lainhart, Andrew L Alexander. Autism Res 2012
20
Lysophospholipid receptors: signaling and biology.
Isao Ishii, Nobuyuki Fukushima, Xiaoqin Ye, Jerold Chun. Annu Rev Biochem 2004
Isao Ishii, Nobuyuki Fukushima, Xiaoqin Ye, Jerold Chun. Annu Rev Biochem 2004
20
The neural basis of fatigue in multiple sclerosis: A multimodal MRI approach.
Ana Margarida Novo, Sonia Batista, Carolina Alves, Otília C d'Almeida, Inês Brás Marques, Carmo Macário, Isabel Santana, Lívia Sousa, Miguel Castelo-Branco, Luís Cunha. Neurol Clin Pract 2018
Ana Margarida Novo, Sonia Batista, Carolina Alves, Otília C d'Almeida, Inês Brás Marques, Carmo Macário, Isabel Santana, Lívia Sousa, Miguel Castelo-Branco, Luís Cunha. Neurol Clin Pract 2018
20
Rapid upregulation of the Pi isoform of glutathione-S-transferase in mouse brains after withdrawal of the neurotoxicant, cuprizone.
F A Tansey, H Zhang, W Cammer. Mol Chem Neuropathol 1997
F A Tansey, H Zhang, W Cammer. Mol Chem Neuropathol 1997
20
MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA sequencing data.
Greg Finak, Andrew McDavid, Masanao Yajima, Jingyuan Deng, Vivian Gersuk, Alex K Shalek, Chloe K Slichter, Hannah W Miller, M Juliana McElrath, Martin Prlic,[...]. Genome Biol 2015
Greg Finak, Andrew McDavid, Masanao Yajima, Jingyuan Deng, Vivian Gersuk, Alex K Shalek, Chloe K Slichter, Hannah W Miller, M Juliana McElrath, Martin Prlic,[...]. Genome Biol 2015
20
Machine Learning Detects Pattern of Differences in Functional Magnetic Resonance Imaging (fMRI) Data between Chronic Fatigue Syndrome (CFS) and Gulf War Illness (GWI).
Destie Provenzano, Stuart D Washington, Yuan J Rao, Murray Loew, James Baraniuk. Brain Sci 2020
Destie Provenzano, Stuart D Washington, Yuan J Rao, Murray Loew, James Baraniuk. Brain Sci 2020
20
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.