Nanxin Liu, Xiaoxiao Pang, Hua Zhang, Ping Ji. Front Immunol 2022
Times Cited: 5
Times Cited: 5
Times Cited
Times Co-cited
Similarity
Molecular mechanisms and cellular functions of cGAS-STING signalling.
Karl-Peter Hopfner, Veit Hornung. Nat Rev Mol Cell Biol 2020
Karl-Peter Hopfner, Veit Hornung. Nat Rev Mol Cell Biol 2020
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The cGAS-STING pathway as a therapeutic target in inflammatory diseases.
Alexiane Decout, Jason D Katz, Shankar Venkatraman, Andrea Ablasser. Nat Rev Immunol 2021
Alexiane Decout, Jason D Katz, Shankar Venkatraman, Andrea Ablasser. Nat Rev Immunol 2021
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Autophagy induction via STING trafficking is a primordial function of the cGAS pathway.
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STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity.
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TRIM30α Is a Negative-Feedback Regulator of the Intracellular DNA and DNA Virus-Triggered Response by Targeting STING.
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The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA.
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Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling.
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Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation.
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DNA sensing by the cGAS-STING pathway in health and disease.
Mona Motwani, Scott Pesiridis, Katherine A Fitzgerald. Nat Rev Genet 2019
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Targeting STING with covalent small-molecule inhibitors.
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Cyclic dinucleotides trigger ULK1 (ATG1) phosphorylation of STING to prevent sustained innate immune signaling.
Hiroyasu Konno, Keiko Konno, Glen N Barber. Cell 2013
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The Cytosolic DNA-Sensing cGAS-STING Pathway in Cancer.
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Analysis of Drosophila STING Reveals an Evolutionarily Conserved Antimicrobial Function.
Marina Martin, Aoi Hiroyasu, R Marena Guzman, Steven A Roberts, Alan G Goodman. Cell Rep 2018
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STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling.
Hiroki Ishikawa, Glen N Barber. Nature 2008
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40
The Ca2+ sensor STIM1 regulates the type I interferon response by retaining the signaling adaptor STING at the endoplasmic reticulum.
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cGAS in action: Expanding roles in immunity and inflammation.
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Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy.
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Microglia-specific overexpression of α-synuclein leads to severe dopaminergic neurodegeneration by phagocytic exhaustion and oxidative toxicity.
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CD4 T cells mediate brain inflammation and neurodegeneration in a mouse model of Parkinson's disease.
Gregory P Williams, Aubrey M Schonhoff, Asta Jurkuvenaite, Nicole J Gallups, David G Standaert, Ashley S Harms. Brain 2021
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Innate and adaptive immune responses in Parkinson's disease.
Aubrey M Schonhoff, Gregory P Williams, Zachary D Wallen, David G Standaert, Ashley S Harms. Prog Brain Res 2020
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20
Impact of monomeric, oligomeric and fibrillar alpha-synuclein on astrocyte reactivity and toxicity to neurons.
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Cecilia Chavarría, Sebastián Rodríguez-Bottero, Celia Quijano, Patricia Cassina, José M Souza. Biochem J 2018
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Mitochondrial damage-associated inflammation highlights biomarkers in PRKN/PINK1 parkinsonism.
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20
STING mediates neurodegeneration and neuroinflammation in nigrostriatal α-synucleinopathy.
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T cell infiltration in both human multiple system atrophy and a novel mouse model of the disease.
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Gregory P Williams, David J Marmion, Aubrey M Schonhoff, Asta Jurkuvenaite, Woong-Jai Won, David G Standaert, Jeffrey H Kordower, Ashley S Harms. Acta Neuropathol 2020
20
The stimulator of interferon genes (STING) pathway is upregulated in striatal astrocytes of patients with multiple system atrophy.
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20
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Treg cell numbers and function in patients with antibiotic-refractory or antibiotic-responsive Lyme arthritis.
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