A citation-based method for searching scientific literature

Inga V Hochheiser, Michael Pilsl, Gregor Hagelueken, Jonas Moecking, Michael Marleaux, Rebecca Brinkschulte, Eicke Latz, Christoph Engel, Matthias Geyer. Nature 2022
Times Cited: 26







List of co-cited articles
298 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation.
Liudmila Andreeva, Liron David, Shaun Rawson, Chen Shen, Teerithveen Pasricha, Pablo Pelegrin, Hao Wu. Cell 2021
34
69

Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome.
Humayun Sharif, Li Wang, Wei Li Wang, Venkat Giri Magupalli, Liudmila Andreeva, Qi Qiao, Arthur V Hauenstein, Zhaolong Wu, Gabriel Núñez, Youdong Mao,[...]. Nature 2019
270
65

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.
Rebecca C Coll, Avril A B Robertson, Jae Jin Chae, Sarah C Higgins, Raúl Muñoz-Planillo, Marco C Inserra, Irina Vetter, Lara S Dungan, Brian G Monks, Andrea Stutz,[...]. Nat Med 2015
53

Crystal Structure of NLRP3 NACHT Domain With an Inhibitor Defines Mechanism of Inflammasome Inhibition.
Carien Dekker, Henri Mattes, Michael Wright, Andreas Boettcher, Alexandra Hinniger, Nicola Hughes, Sandra Kapps-Fouthier, Jörg Eder, Paulus Erbel, Nikolaus Stiefl,[...]. J Mol Biol 2021
20
65

MCC950 closes the active conformation of NLRP3 to an inactive state.
Ana Tapia-Abellán, Diego Angosto-Bazarra, Helios Martínez-Banaclocha, Carlos de Torre-Minguela, Jose P Cerón-Carrasco, Horacio Pérez-Sánchez, Juan I Arostegui, Pablo Pelegrin. Nat Chem Biol 2019
167
46

MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition.
Rebecca C Coll, James R Hill, Christopher J Day, Alina Zamoshnikova, Dave Boucher, Nicholas L Massey, Jessica L Chitty, James A Fraser, Michael P Jennings, Avril A B Robertson,[...]. Nat Chem Biol 2019
337
46


NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux.
Yuan He, Melody Y Zeng, Dahai Yang, Benny Motro, Gabriel Núñez. Nature 2016
593
42

NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component.
Hexin Shi, Ying Wang, Xiaohong Li, Xiaoming Zhan, Miao Tang, Maggy Fina, Lijing Su, David Pratt, Chun Hui Bu, Sara Hildebrand,[...]. Nat Immunol 2016
389
38

Gout-associated uric acid crystals activate the NALP3 inflammasome.
Fabio Martinon, Virginie Pétrilli, Annick Mayor, Aubry Tardivel, Jürg Tschopp. Nature 2006
38

The NLRP3 inflammasome: molecular activation and regulation to therapeutics.
Karen V Swanson, Meng Deng, Jenny P-Y Ting. Nat Rev Immunol 2019
38

Targeting the NLRP3 inflammasome in inflammatory diseases.
Matthew S J Mangan, Edward J Olhava, William R Roush, H Martin Seidel, Gary D Glick, Eicke Latz. Nat Rev Drug Discov 2018
618
34

A Genome-wide CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) Screen Identifies NEK7 as an Essential Component of NLRP3 Inflammasome Activation.
Jonathan L Schmid-Burgk, Dhruv Chauhan, Tobias Schmidt, Thomas S Ebert, Julia Reinhardt, Elmar Endl, Veit Hornung. J Biol Chem 2016
263
30


Sensing low intracellular potassium by NLRP3 results in a stable open structure that promotes inflammasome activation.
Ana Tapia-Abellán, Diego Angosto-Bazarra, Cristina Alarcón-Vila, María C Baños, Iva Hafner-Bratkovič, Baldomero Oliva, Pablo Pelegrín. Sci Adv 2021
18
38

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.
Nobuhiko Kayagaki, Irma B Stowe, Bettina L Lee, Karen O'Rourke, Keith Anderson, Søren Warming, Trinna Cuellar, Benjamin Haley, Merone Roose-Girma, Qui T Phung,[...]. Nature 2015
26

K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter.
Raúl Muñoz-Planillo, Peter Kuffa, Giovanny Martínez-Colón, Brenna L Smith, Thekkelnaycke M Rajendiran, Gabriel Núñez. Immunity 2013
26

Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.
Franz G Bauernfeind, Gabor Horvath, Andrea Stutz, Emad S Alnemri, Kelly MacDonald, David Speert, Teresa Fernandes-Alnemri, Jianghong Wu, Brian G Monks, Katherine A Fitzgerald,[...]. J Immunol 2009
26

Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders.
Hua Jiang, Hongbin He, Yun Chen, Wei Huang, Jinbo Cheng, Jin Ye, Aoli Wang, Jinhui Tao, Chao Wang, Qingsong Liu,[...]. J Exp Med 2017
318
26

Structural basis for the oligomerization-mediated regulation of NLRP3 inflammasome activation.
Umeharu Ohto, Yukie Kamitsukasa, Hanako Ishida, Zhikuan Zhang, Karin Murakami, Chie Hirama, Sakiko Maekawa, Toshiyuki Shimizu. Proc Natl Acad Sci U S A 2022
9
77

Inflammasomes: mechanism of assembly, regulation and signalling.
Petr Broz, Vishva M Dixit. Nat Rev Immunol 2016
23

Human NLRP1 is a sensor for double-stranded RNA.
Stefan Bauernfried, Matthias J Scherr, Andreas Pichlmair, Karl E Duderstadt, Veit Hornung. Science 2021
90
23

N-terminal degradation activates the NLRP1B inflammasome.
Ashley J Chui, Marian C Okondo, Sahana D Rao, Kuo Gai, Andrew R Griswold, Darren C Johnson, Daniel P Ball, Cornelius Y Taabazuing, Elizabeth L Orth, Brooke A Vittimberga,[...]. Science 2019
140
23

Diverse viral proteases activate the NLRP1 inflammasome.
Brian V Tsu, Christopher Beierschmitt, Andrew P Ryan, Rimjhim Agarwal, Patrick S Mitchell, Matthew D Daugherty. Elife 2021
48
23

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Jianjin Shi, Yue Zhao, Kun Wang, Xuyan Shi, Yue Wang, Huanwei Huang, Yinghua Zhuang, Tao Cai, Fengchao Wang, Feng Shao. Nature 2015
23

OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation.
Carlo Marchetti, Benjamin Swartzwelter, Fabia Gamboni, Charles P Neff, Katrin Richter, Tania Azam, Sonia Carta, Isak Tengesdal, Travis Nemkov, Angelo D'Alessandro,[...]. Proc Natl Acad Sci U S A 2018
225
23

Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization.
Liman Zhang, Shuobing Chen, Jianbin Ruan, Jiayi Wu, Alexander B Tong, Qian Yin, Yang Li, Liron David, Alvin Lu, Wei Li Wang,[...]. Science 2015
242
23

Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes.
Alvin Lu, Venkat Giri Magupalli, Jianbin Ruan, Qian Yin, Maninjay K Atianand, Matthijn R Vos, Gunnar F Schröder, Katherine A Fitzgerald, Hao Wu, Edward H Egelman. Cell 2014
759
23

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization.
Veit Hornung, Franz Bauernfeind, Annett Halle, Eivind O Samstad, Hajime Kono, Kenneth L Rock, Katherine A Fitzgerald, Eicke Latz. Nat Immunol 2008
23

NLRP3 inflammasome assembly is regulated by phosphorylation of the pyrin domain.
Andrea Stutz, Carl-Christian Kolbe, Rainer Stahl, Gabor L Horvath, Bernardo S Franklin, Olivia van Ray, Rebecca Brinkschulte, Matthias Geyer, Felix Meissner, Eicke Latz. J Exp Med 2017
185
19

HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation.
Venkat Giri Magupalli, Roberto Negro, Yuzi Tian, Arthur V Hauenstein, Giuseppe Di Caprio, Wesley Skillern, Qiufang Deng, Pontus Orning, Hasan B Alam, Zoltan Maliga,[...]. Science 2020
104
19

Targeting the NLRP3 inflammasome in inflammatory diseases.
Matthew S J Mangan, Edward J Olhava, William R Roush, H Martin Seidel, Gary D Glick, Eicke Latz. Nat Rev Drug Discov 2018
178
19

Pharmacological Inhibitors of the NLRP3 Inflammasome.
Ayesha Zahid, Bofeng Li, Arnaud John Kombe Kombe, Tengchuan Jin, Jinhui Tao. Front Immunol 2019
268
19

NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.
Michael T Heneka, Markus P Kummer, Andrea Stutz, Andrea Delekate, Stephanie Schwartz, Ana Vieira-Saecker, Angelika Griep, Daisy Axt, Anita Remus, Te-Chen Tzeng,[...]. Nature 2013
19

The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation.
Nathan Kelley, Devon Jeltema, Yanhui Duan, Yuan He. Int J Mol Sci 2019
926
19

Mechanisms and functions of inflammasomes.
Mohamed Lamkanfi, Vishva M Dixit. Cell 2014
19

NLRP3 Phosphorylation Is an Essential Priming Event for Inflammasome Activation.
Nan Song, Zhao-Shan Liu, Wen Xue, Zhao-Fang Bai, Qian-Yi Wang, Jiang Dai, Xin Liu, Yi-Jiao Huang, Hong Cai, Xiao-Yan Zhan,[...]. Mol Cell 2017
228
19

Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation.
Christine Juliana, Teresa Fernandes-Alnemri, Seokwon Kang, Andrew Farias, Fengsong Qin, Emad S Alnemri. J Biol Chem 2012
469
19

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Peter Duewell, Hajime Kono, Katey J Rayner, Cherilyn M Sirois, Gregory Vladimer, Franz G Bauernfeind, George S Abela, Luigi Franchi, Gabriel Nuñez, Max Schnurr,[...]. Nature 2010
19

MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition.
Lieselotte Vande Walle, Irma B Stowe, Pavel Šácha, Bettina L Lee, Dieter Demon, Amelie Fossoul, Filip Van Hauwermeiren, Pedro H V Saavedra, Petr Šimon, Vladimír Šubrt,[...]. PLoS Biol 2019
61
19

Gasdermin D pore structure reveals preferential release of mature interleukin-1.
Shiyu Xia, Zhibin Zhang, Venkat Giri Magupalli, Juan Lorenzo Pablo, Ying Dong, Setu M Vora, Longfei Wang, Tian-Min Fu, Matthew P Jacobson, Anna Greka,[...]. Nature 2021
109
19

Functional degradation: A mechanism of NLRP1 inflammasome activation by diverse pathogen enzymes.
Andrew Sandstrom, Patrick S Mitchell, Lisa Goers, Edward W Mu, Cammie F Lesser, Russell E Vance. Science 2019
167
19

Enteroviral 3C protease activates the human NLRP1 inflammasome in airway epithelia.
Kim S Robinson, Daniel Eng Thiam Teo, Kai Sen Tan, Gee Ann Toh, Hsiao Hui Ong, Chrissie Kaishi Lim, Kenneth Lay, Bijin Veonice Au, Tian Sheng Lew, Justin Jang Hann Chu,[...]. Science 2020
69
19

Tranilast directly targets NLRP3 to treat inflammasome-driven diseases.
Yi Huang, Hua Jiang, Yun Chen, Xiaqiong Wang, Yanqing Yang, Jinhui Tao, Xianming Deng, Gaolin Liang, Huafeng Zhang, Wei Jiang,[...]. EMBO Mol Med 2018
212
19

Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity.
Hongbin He, Hua Jiang, Yun Chen, Jin Ye, Aoli Wang, Chao Wang, Qingsong Liu, Gaolin Liang, Xianming Deng, Wei Jiang,[...]. Nat Commun 2018
263
19

Structural and biochemical basis for induced self-propagation of NLRC4.
Zehan Hu, Qiang Zhou, Chenlu Zhang, Shilong Fan, Wei Cheng, Yue Zhao, Feng Shao, Hong-Wei Wang, Sen-Fang Sui, Jijie Chai. Science 2015
220
19

The inflammasomes.
Kate Schroder, Jurg Tschopp. Cell 2010
15

Inflammasomes: mechanism of action, role in disease, and therapeutics.
Haitao Guo, Justin B Callaway, Jenny P-Y Ting. Nat Med 2015
15

The NALP3 inflammasome is involved in the innate immune response to amyloid-beta.
Annett Halle, Veit Hornung, Gabor C Petzold, Cameron R Stewart, Brian G Monks, Thomas Reinheckel, Katherine A Fitzgerald, Eicke Latz, Kathryn J Moore, Douglas T Golenbock. Nat Immunol 2008
15

Crystal structure of NLRC4 reveals its autoinhibition mechanism.
Zehan Hu, Chuangye Yan, Peiyuan Liu, Zhiwei Huang, Rui Ma, Chenlu Zhang, Ruiyong Wang, Yueteng Zhang, Fabio Martinon, Di Miao,[...]. Science 2013
252
15


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.