C Robert, K D Lewis, R Gutzmer, D Stroyakovskiy, H Gogas, S Protsenko, R P Pereira, T Eigentler, P Rutkowski, L Demidov, I Caro, H Forbes, K Shah, Y Yan, H Li, G A McArthur, P A Ascierto. Ann Oncol 2022
Times Cited: 2
Times Cited: 2
Times Cited
Times Co-cited
Similarity
Randomized Phase III Trial Evaluating Spartalizumab Plus Dabrafenib and Trametinib for BRAF V600-Mutant Unresectable or Metastatic Melanoma.
Reinhard Dummer, Georgina V Long, Caroline Robert, Hussein A Tawbi, Keith T Flaherty, Paolo A Ascierto, Paul D Nathan, Piotr Rutkowski, Oleg Leonov, Caroline Dutriaux,[...]. J Clin Oncol 2022
Reinhard Dummer, Georgina V Long, Caroline Robert, Hussein A Tawbi, Keith T Flaherty, Paolo A Ascierto, Paul D Nathan, Piotr Rutkowski, Oleg Leonov, Caroline Dutriaux,[...]. J Clin Oncol 2022
100
KEYNOTE-022 part 3: a randomized, double-blind, phase 2 study of pembrolizumab, dabrafenib, and trametinib in BRAF-mutant melanoma.
Pier Francesco Ferrucci, Anna Maria Di Giacomo, Michele Del Vecchio, Victoria Atkinson, Henrik Schmidt, Jacob Schachter, Paola Queirolo, Georgina V Long, Rosalie Stephens, Inge Marie Svane,[...]. J Immunother Cancer 2020
Pier Francesco Ferrucci, Anna Maria Di Giacomo, Michele Del Vecchio, Victoria Atkinson, Henrik Schmidt, Jacob Schachter, Paola Queirolo, Georgina V Long, Rosalie Stephens, Inge Marie Svane,[...]. J Immunother Cancer 2020
100
Adjuvant dabrafenib plus trametinib versus placebo in patients with resected, BRAFV600-mutant, stage III melanoma (COMBI-AD): exploratory biomarker analyses from a randomised, phase 3 trial.
Reinhard Dummer, Jan C Brase, James Garrett, Catarina D Campbell, Eduard Gasal, Matthew Squires, Daniel Gusenleitner, Mario Santinami, Victoria Atkinson, Mario Mandalà,[...]. Lancet Oncol 2020
Reinhard Dummer, Jan C Brase, James Garrett, Catarina D Campbell, Eduard Gasal, Matthew Squires, Daniel Gusenleitner, Mario Santinami, Victoria Atkinson, Mario Mandalà,[...]. Lancet Oncol 2020
100
Pembrolizumab versus ipilimumab in advanced melanoma (KEYNOTE-006): post-hoc 5-year results from an open-label, multicentre, randomised, controlled, phase 3 study.
Caroline Robert, Antoni Ribas, Jacob Schachter, Ana Arance, Jean-Jacques Grob, Laurent Mortier, Adil Daud, Matteo S Carlino, Catriona M McNeil, Michal Lotem,[...]. Lancet Oncol 2019
Caroline Robert, Antoni Ribas, Jacob Schachter, Ana Arance, Jean-Jacques Grob, Laurent Mortier, Adil Daud, Matteo S Carlino, Catriona M McNeil, Michal Lotem,[...]. Lancet Oncol 2019
100
BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma.
Dennie T Frederick, Adriano Piris, Alexandria P Cogdill, Zachary A Cooper, Cecilia Lezcano, Cristina R Ferrone, Devarati Mitra, Andrea Boni, Lindsay P Newton, Chengwen Liu,[...]. Clin Cancer Res 2013
Dennie T Frederick, Adriano Piris, Alexandria P Cogdill, Zachary A Cooper, Cecilia Lezcano, Cristina R Ferrone, Devarati Mitra, Andrea Boni, Lindsay P Newton, Chengwen Liu,[...]. Clin Cancer Res 2013
100
Atezolizumab, vemurafenib, and cobimetinib as first-line treatment for unresectable advanced BRAFV600 mutation-positive melanoma (IMspire150): primary analysis of the randomised, double-blind, placebo-controlled, phase 3 trial.
Ralf Gutzmer, Daniil Stroyakovskiy, Helen Gogas, Caroline Robert, Karl Lewis, Svetlana Protsenko, Rodrigo P Pereira, Thomas Eigentler, Piotr Rutkowski, Lev Demidov,[...]. Lancet 2020
Ralf Gutzmer, Daniil Stroyakovskiy, Helen Gogas, Caroline Robert, Karl Lewis, Svetlana Protsenko, Rodrigo P Pereira, Thomas Eigentler, Piotr Rutkowski, Lev Demidov,[...]. Lancet 2020
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Update on tolerability and overall survival in COLUMBUS: landmark analysis of a randomised phase 3 trial of encorafenib plus binimetinib vs vemurafenib or encorafenib in patients with BRAF V600-mutant melanoma.
Paolo A Ascierto, Reinhard Dummer, Helen J Gogas, Keith T Flaherty, Ana Arance, Mario Mandala, Gabriella Liszkay, Claus Garbe, Dirk Schadendorf, Ivana Krajsova,[...]. Eur J Cancer 2020
Paolo A Ascierto, Reinhard Dummer, Helen J Gogas, Keith T Flaherty, Ana Arance, Mario Mandala, Gabriella Liszkay, Claus Garbe, Dirk Schadendorf, Ivana Krajsova,[...]. Eur J Cancer 2020
100
An Altered Ratio of CD4+ And CD8+ T Lymphocytes in Cervical Cancer Tissues and Peripheral Blood – A Prognostic Clue?
Diptimoy Das, Basab Sarkar, Sandip Mukhopadhyay, Chandranath Banerjee, Supreeti Biswas Mondal. Asian Pac J Cancer Prev 2018
Diptimoy Das, Basab Sarkar, Sandip Mukhopadhyay, Chandranath Banerjee, Supreeti Biswas Mondal. Asian Pac J Cancer Prev 2018
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Predictive and prognostic value of circulating blood lymphocyte subsets in metastatic breast cancer.
Jian Yang, Junnan Xu, Ying E, Tao Sun. Cancer Med 2019
Jian Yang, Junnan Xu, Ying E, Tao Sun. Cancer Med 2019
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CD4/CD8 ratio is a prognostic factor in IgG nonresponders among peptide vaccine-treated ovarian cancer patients.
Kayoko Waki, Kouichiro Kawano, Naotake Tsuda, Nobukazu Komatsu, Akira Yamada. Cancer Sci 2020
Kayoko Waki, Kouichiro Kawano, Naotake Tsuda, Nobukazu Komatsu, Akira Yamada. Cancer Sci 2020
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TMB and Inflammatory Gene Expression Associated with Clinical Outcomes following Immunotherapy in Advanced Melanoma.
F Stephen Hodi, Jedd D Wolchok, Dirk Schadendorf, James Larkin, Georgina V Long, Xiaozhong Qian, Abdel Saci, Tina C Young, Sujaya Srinivasan, Han Chang,[...]. Cancer Immunol Res 2021
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50
Selective BRAF inhibitors induce marked T-cell infiltration into human metastatic melanoma.
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Immunological effects of BRAF+MEK inhibition.
Paolo A Ascierto, Reinhard Dummer. Oncoimmunology 2018
Paolo A Ascierto, Reinhard Dummer. Oncoimmunology 2018
50
Pan-tumor genomic biomarkers for PD-1 checkpoint blockade-based immunotherapy.
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Distinct Molecular Profiles and Immunotherapy Treatment Outcomes of V600E and V600K BRAF-Mutant Melanoma.
Inês Pires da Silva, Kevin Y X Wang, James S Wilmott, Jeff Holst, Matteo S Carlino, John J Park, Camelia Quek, Matthew Wongchenko, Yibing Yan, Graham Mann,[...]. Clin Cancer Res 2019
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50
Programmed Death-Ligand 1 Expression and Response to the Anti-Programmed Death 1 Antibody Pembrolizumab in Melanoma.
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Circulating tumour DNA predicts response to anti-PD1 antibodies in metastatic melanoma.
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Robust Antitumor Responses Result from Local Chemotherapy and CTLA-4 Blockade.
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The Molecular Signatures Database (MSigDB) hallmark gene set collection.
Arthur Liberzon, Chet Birger, Helga Thorvaldsdóttir, Mahmoud Ghandi, Jill P Mesirov, Pablo Tamayo. Cell Syst 2015
Arthur Liberzon, Chet Birger, Helga Thorvaldsdóttir, Mahmoud Ghandi, Jill P Mesirov, Pablo Tamayo. Cell Syst 2015
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T-cell invigoration to tumour burden ratio associated with anti-PD-1 response.
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Five-Year Outcomes with Dabrafenib plus Trametinib in Metastatic Melanoma.
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Ipilimumab with Stereotactic Ablative Radiation Therapy: Phase I Results and Immunologic Correlates from Peripheral T Cells.
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50
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.
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Circulating tumour DNA in patients with advanced melanoma treated with dabrafenib or dabrafenib plus trametinib: a clinical validation study.
Mahrukh M Syeda, Jennifer M Wiggins, Broderick C Corless, Georgina V Long, Keith T Flaherty, Dirk Schadendorf, Paul D Nathan, Caroline Robert, Antoni Ribas, Michael A Davies,[...]. Lancet Oncol 2021
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50
Correlation of BRAF Mutation Status in Circulating-Free DNA and Tumor and Association with Clinical Outcome across Four BRAFi and MEKi Clinical Trials.
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50
Five-Year Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma.
James Larkin, Vanna Chiarion-Sileni, Rene Gonzalez, Jean-Jacques Grob, Piotr Rutkowski, Christopher D Lao, C Lance Cowey, Dirk Schadendorf, John Wagstaff, Reinhard Dummer,[...]. N Engl J Med 2019
James Larkin, Vanna Chiarion-Sileni, Rene Gonzalez, Jean-Jacques Grob, Piotr Rutkowski, Christopher D Lao, C Lance Cowey, Dirk Schadendorf, John Wagstaff, Reinhard Dummer,[...]. N Engl J Med 2019
50
5-Year Outcomes with Cobimetinib plus Vemurafenib in BRAFV600 Mutation-Positive Advanced Melanoma: Extended Follow-up of the coBRIM Study.
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50
Combined PD-1, BRAF and MEK inhibition in advanced BRAF-mutant melanoma: safety run-in and biomarker cohorts of COMBI-i.
Reinhard Dummer, Celeste Lebbé, Victoria Atkinson, Mario Mandalà, Paul D Nathan, Ana Arance, Erika Richtig, Naoya Yamazaki, Caroline Robert, Dirk Schadendorf,[...]. Nat Med 2020
Reinhard Dummer, Celeste Lebbé, Victoria Atkinson, Mario Mandalà, Paul D Nathan, Ana Arance, Erika Richtig, Naoya Yamazaki, Caroline Robert, Dirk Schadendorf,[...]. Nat Med 2020
50
PI3K Inhibitors in Cancer: Clinical Implications and Adverse Effects.
Rosalin Mishra, Hima Patel, Samar Alanazi, Mary Kate Kilroy, Joan T Garrett. Int J Mol Sci 2021
Rosalin Mishra, Hima Patel, Samar Alanazi, Mary Kate Kilroy, Joan T Garrett. Int J Mol Sci 2021
50
Intermittent administration of MEK inhibitor GDC-0973 plus PI3K inhibitor GDC-0941 triggers robust apoptosis and tumor growth inhibition.
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Klaus P Hoeflich, Mark Merchant, Christine Orr, Jocelyn Chan, Doug Den Otter, Leanne Berry, Ian Kasman, Hartmut Koeppen, Ken Rice, Nai-Ying Yang,[...]. Cancer Res 2012
50
Hiding in the dark: pan-cancer characterization of expression and clinical relevance of CD40 to immune checkpoint blockade therapy.
Chi Yan, Ann Richmond. Mol Cancer 2021
Chi Yan, Ann Richmond. Mol Cancer 2021
50
Targeting BMK1 Impairs the Drug Resistance to Combined Inhibition of BRAF and MEK1/2 in Melanoma.
Chengli Song, Lina Wang, Qiang Xu, Kai Wang, Dan Xie, Zhe Yu, Kui Jiang, Lujian Liao, John R Yates, Jiing-Dwan Lee,[...]. Sci Rep 2017
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50
The Role of PI3K Inhibition in the Treatment of Breast Cancer, Alone or Combined With Immune Checkpoint Inhibitors.
Zhizhu Zhang, Ann Richmond. Front Mol Biosci 2021
Zhizhu Zhang, Ann Richmond. Front Mol Biosci 2021
50
Suppression of insulin feedback enhances the efficacy of PI3K inhibitors.
Benjamin D Hopkins, Chantal Pauli, Xing Du, Diana G Wang, Xiang Li, David Wu, Solomon C Amadiume, Marcus D Goncalves, Cindy Hodakoski, Mark R Lundquist,[...]. Nature 2018
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Targeting the MAPK and PI3K pathways in combination with PD1 blockade in melanoma.
Marcel A Deken, Jules Gadiot, Ekaterina S Jordanova, Ruben Lacroix, Melissa van Gool, Paula Kroon, Cristina Pineda, Marnix H Geukes Foppen, Richard Scolyer, Ji-Ying Song,[...]. Oncoimmunology 2016
Marcel A Deken, Jules Gadiot, Ekaterina S Jordanova, Ruben Lacroix, Melissa van Gool, Paula Kroon, Cristina Pineda, Marnix H Geukes Foppen, Richard Scolyer, Ji-Ying Song,[...]. Oncoimmunology 2016
50
At a crossroads: how to translate the roles of PI3K in oncogenic and metabolic signalling into improvements in cancer therapy.
Neil Vasan, Lewis C Cantley. Nat Rev Clin Oncol 2022
Neil Vasan, Lewis C Cantley. Nat Rev Clin Oncol 2022
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AKT Degradation Selectively Inhibits the Growth of PI3K/PTEN Pathway-Mutant Cancers with Wild-Type KRAS and BRAF by Destabilizing Aurora Kinase B.
Jia Xu, Xufen Yu, Tiphaine C Martin, Ankita Bansal, Kakit Cheung, Abigail Lubin, Elias Stratikopoulos, Kaitlyn M Cahuzac, Li Wang, Ling Xie,[...]. Cancer Discov 2021
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50
Activation of IGF1R/p110β/AKT/mTOR confers resistance to α-specific PI3K inhibition.
Cedric Leroy, Pedro Ramos, Karen Cornille, Debora Bonenfant, Christine Fritsch, Hans Voshol, Mohamed Bentires-Alj. Breast Cancer Res 2016
Cedric Leroy, Pedro Ramos, Karen Cornille, Debora Bonenfant, Christine Fritsch, Hans Voshol, Mohamed Bentires-Alj. Breast Cancer Res 2016
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mTOR kinase inhibition causes feedback-dependent biphasic regulation of AKT signaling.
Vanessa S Rodrik-Outmezguine, Sarat Chandarlapaty, Nen C Pagano, Poulikos I Poulikakos, Maurizio Scaltriti, Elizabeth Moskatel, José Baselga, Sylvie Guichard, Neal Rosen. Cancer Discov 2011
Vanessa S Rodrik-Outmezguine, Sarat Chandarlapaty, Nen C Pagano, Poulikos I Poulikakos, Maurizio Scaltriti, Elizabeth Moskatel, José Baselga, Sylvie Guichard, Neal Rosen. Cancer Discov 2011
50
Alpelisib plus fulvestrant for PIK3CA-mutated, hormone receptor-positive, human epidermal growth factor receptor-2-negative advanced breast cancer: final overall survival results from SOLAR-1.
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How Compensatory Mechanisms and Adaptive Rewiring Have Shaped Our Understanding of Therapeutic Resistance in Cancer.
Johann S Bergholz, Jean J Zhao. Cancer Res 2021
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Acquired resistance to anti-MAPK targeted therapy confers an immune-evasive tumor microenvironment and cross-resistance to immunotherapy in melanoma.
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Skp2-dependent reactivation of AKT drives resistance to PI3K inhibitors.
Emilie Clement, Hiroyuki Inuzuka, Naoe T Nihira, Wenyi Wei, Alex Toker. Sci Signal 2018
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Host immunity contributes to the anti-melanoma activity of BRAF inhibitors.
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Novel induction of CD40 expression by tumor cells with RAS/RAF/PI3K pathway inhibition augments response to checkpoint blockade.
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A phase Ib dose-escalation and expansion study of the oral MEK inhibitor pimasertib and PI3K/MTOR inhibitor voxtalisib in patients with advanced solid tumours.
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Mammalian target of rapamycin inhibitors activate the AKT kinase in multiple myeloma cells by up-regulating the insulin-like growth factor receptor/insulin receptor substrate-1/phosphatidylinositol 3-kinase cascade.
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A dual pathway inhibition strategy using BKM120 combined with vemurafenib is poorly tolerated in BRAF V600E/K mutant advanced melanoma.
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Inhibitors of HSP90 block p95-HER2 signaling in Trastuzumab-resistant tumors and suppress their growth.
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50
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.