John A Lupisella, Pravin S Shirude, Nicholas R Wurtz, Ricardo A Garcia. Semin Immunol 2022
Times Cited: 3
Times Cited: 3
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Formyl peptide receptor type 2 agonists to kick-start resolution pharmacology.
Mauro Perretti, Catherine Godson. Br J Pharmacol 2020
Mauro Perretti, Catherine Godson. Br J Pharmacol 2020
100
Recent advances in the design and development of formyl peptide receptor 2 (FPR2/ALX) agonists as pro-resolving agents with diverse therapeutic potential.
Monika Maciuszek, Antonino Cacace, Eoin Brennan, Catherine Godson, Timothy M Chapman. Eur J Med Chem 2021
Monika Maciuszek, Antonino Cacace, Eoin Brennan, Catherine Godson, Timothy M Chapman. Eur J Med Chem 2021
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Discovery of BMS-986235/LAR-1219: A Potent Formyl Peptide Receptor 2 (FPR2) Selective Agonist for the Prevention of Heart Failure.
Yoshikazu Asahina, Nicholas R Wurtz, Kazuto Arakawa, Nancy Carson, Kiyoshi Fujii, Kazunori Fukuchi, Ricardo Garcia, Mei-Yin Hsu, Junichi Ishiyama, Bruce Ito,[...]. J Med Chem 2020
Yoshikazu Asahina, Nicholas R Wurtz, Kazuto Arakawa, Nancy Carson, Kiyoshi Fujii, Kazunori Fukuchi, Ricardo Garcia, Mei-Yin Hsu, Junichi Ishiyama, Bruce Ito,[...]. J Med Chem 2020
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Resolvin E1 promotes mucosal surface clearance of neutrophils: a new paradigm for inflammatory resolution.
Eric L Campbell, Nancy A Louis, Sarah E Tomassetti, Geraldine O Canny, Makoto Arita, Charles N Serhan, Sean P Colgan. FASEB J 2007
Eric L Campbell, Nancy A Louis, Sarah E Tomassetti, Geraldine O Canny, Makoto Arita, Charles N Serhan, Sean P Colgan. FASEB J 2007
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Preservation of Post-Infarction Cardiac Structure and Function via Long-Term Oral Formyl Peptide Receptor Agonist Treatment.
Ricardo A García, Bruce R Ito, John A Lupisella, Nancy A Carson, Mei-Yin Hsu, Gayani Fernando, Madeleine Heroux, Michel Bouvier, Elizabeth Dierks, Ellen K Kick,[...]. JACC Basic Transl Sci 2019
Ricardo A García, Bruce R Ito, John A Lupisella, Nancy A Carson, Mei-Yin Hsu, Gayani Fernando, Madeleine Heroux, Michel Bouvier, Elizabeth Dierks, Ellen K Kick,[...]. JACC Basic Transl Sci 2019
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Small-molecule-biased formyl peptide receptor agonist compound 17b protects against myocardial ischaemia-reperfusion injury in mice.
Cheng Xue Qin, Lauren T May, Renming Li, Nga Cao, Sarah Rosli, Minh Deo, Amy E Alexander, Duncan Horlock, Jane E Bourke, Yuan H Yang,[...]. Nat Commun 2017
Cheng Xue Qin, Lauren T May, Renming Li, Nga Cao, Sarah Rosli, Minh Deo, Amy E Alexander, Duncan Horlock, Jane E Bourke, Yuan H Yang,[...]. Nat Commun 2017
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Resolvin D1 binds human phagocytes with evidence for proresolving receptors.
Sriram Krishnamoorthy, Antonio Recchiuti, Nan Chiang, Stephanie Yacoubian, Chih-Hao Lee, Rong Yang, Nicos A Petasis, Charles N Serhan. Proc Natl Acad Sci U S A 2010
Sriram Krishnamoorthy, Antonio Recchiuti, Nan Chiang, Stephanie Yacoubian, Chih-Hao Lee, Rong Yang, Nicos A Petasis, Charles N Serhan. Proc Natl Acad Sci U S A 2010
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Resolution of inflammation: the beginning programs the end.
Charles N Serhan, John Savill. Nat Immunol 2005
Charles N Serhan, John Savill. Nat Immunol 2005
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Resolvin E1 and protectin D1 activate inflammation-resolution programmes.
Jan M Schwab, Nan Chiang, Makoto Arita, Charles N Serhan. Nature 2007
Jan M Schwab, Nan Chiang, Makoto Arita, Charles N Serhan. Nature 2007
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Cutting edge: lipoxins rapidly stimulate nonphlogistic phagocytosis of apoptotic neutrophils by monocyte-derived macrophages.
C Godson, S Mitchell, K Harvey, N A Petasis, N Hogg, H R Brady. J Immunol 2000
C Godson, S Mitchell, K Harvey, N A Petasis, N Hogg, H R Brady. J Immunol 2000
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Biomarker-guided clinical development of the first-in-class anti-inflammatory FPR2/ALX agonist ACT-389949.
Anna K Stalder, Dominik Lott, Daniel S Strasser, Hans G Cruz, Andreas Krause, Peter M A Groenen, Jasper Dingemanse. Br J Clin Pharmacol 2017
Anna K Stalder, Dominik Lott, Daniel S Strasser, Hans G Cruz, Andreas Krause, Peter M A Groenen, Jasper Dingemanse. Br J Clin Pharmacol 2017
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Total synthesis and bioactivity of resolvin E2.
Seiji Ogawa, Daisuke Urabe, Yoshiyuki Yokokura, Hiroyuki Arai, Makoto Arita, Masayuki Inoue. Org Lett 2009
Seiji Ogawa, Daisuke Urabe, Yoshiyuki Yokokura, Hiroyuki Arai, Makoto Arita, Masayuki Inoue. Org Lett 2009
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Lipid mediator class switching during acute inflammation: signals in resolution.
B D Levy, C B Clish, B Schmidt, K Gronert, C N Serhan. Nat Immunol 2001
B D Levy, C B Clish, B Schmidt, K Gronert, C N Serhan. Nat Immunol 2001
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Lipoxins: revelations on resolution.
B McMahon, S Mitchell, H R Brady, C Godson. Trends Pharmacol Sci 2001
B McMahon, S Mitchell, H R Brady, C Godson. Trends Pharmacol Sci 2001
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Arachidonic acid promotes phosphorylation of 5-lipoxygenase at Ser-271 by MAPK-activated protein kinase 2 (MK2).
Oliver Werz, Dagmar Szellas, Dieter Steinhilber, Olof Rådmark. J Biol Chem 2002
Oliver Werz, Dagmar Szellas, Dieter Steinhilber, Olof Rådmark. J Biol Chem 2002
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Nikolai N. Anitschkow and the lipid hypothesis of atherosclerosis.
L Maximilian Buja. Cardiovasc Pathol 2014
L Maximilian Buja. Cardiovasc Pathol 2014
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Lipoxin A4: a new class of ligand for the Ah receptor.
C M Schaldach, J Riby, L F Bjeldanes. Biochemistry 1999
C M Schaldach, J Riby, L F Bjeldanes. Biochemistry 1999
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The resolution of inflammation: New mechanisms in patho-physiology open opportunities for pharmacology.
Mauro Perretti. Semin Immunol 2015
Mauro Perretti. Semin Immunol 2015
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Diversity of macrophage phenotypes and responses in atherosclerosis.
Hiroyuki Jinnouchi, Liang Guo, Atsushi Sakamoto, Sho Torii, Yu Sato, Anne Cornelissen, Salome Kuntz, Ka Hyun Paek, Raquel Fernandez, Daniela Fuller,[...]. Cell Mol Life Sci 2020
Hiroyuki Jinnouchi, Liang Guo, Atsushi Sakamoto, Sho Torii, Yu Sato, Anne Cornelissen, Salome Kuntz, Ka Hyun Paek, Raquel Fernandez, Daniela Fuller,[...]. Cell Mol Life Sci 2020
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Lipoxin and resolvin biosynthesis is dependent on 5-lipoxygenase activating protein.
Christoph Lehmann, Julia Homann, Ann-Katrin Ball, René Blöcher, Thea K Kleinschmidt, Devaraj Basavarajappa, Carlo Angioni, Nerea Ferreirós, Ann-Kathrin Häfner, Olof Rådmark,[...]. FASEB J 2015
Christoph Lehmann, Julia Homann, Ann-Katrin Ball, René Blöcher, Thea K Kleinschmidt, Devaraj Basavarajappa, Carlo Angioni, Nerea Ferreirós, Ann-Kathrin Häfner, Olof Rådmark,[...]. FASEB J 2015
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Atherosclerosis.
Peter Libby, Julie E Buring, Lina Badimon, Göran K Hansson, John Deanfield, Márcio Sommer Bittencourt, Lale Tokgözoğlu, Eldrin F Lewis. Nat Rev Dis Primers 2019
Peter Libby, Julie E Buring, Lina Badimon, Göran K Hansson, John Deanfield, Márcio Sommer Bittencourt, Lale Tokgözoğlu, Eldrin F Lewis. Nat Rev Dis Primers 2019
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The resolution code of acute inflammation: Novel pro-resolving lipid mediators in resolution.
Charles N Serhan, Nan Chiang, Jesmond Dalli. Semin Immunol 2015
Charles N Serhan, Nan Chiang, Jesmond Dalli. Semin Immunol 2015
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Dysfunctional Vascular Endothelium as a Driver of Atherosclerosis: Emerging Insights Into Pathogenesis and Treatment.
Steven R Botts, Jason E Fish, Kathryn L Howe. Front Pharmacol 2021
Steven R Botts, Jason E Fish, Kathryn L Howe. Front Pharmacol 2021
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Resolvin D1 Ameliorates Nicotinamide-streptozotocin-induced Type 2 Diabetes Mellitus by its Anti-inflammatory Action and Modulating PI3K/Akt/mTOR Pathway in the Brain.
Siresha Bathina, Naveen K V Gundala, Poorani Rhenghachar, Sailaja Polavarapu, Anasuya D Hari, Monika Sadananda, Undurti N Das. Arch Med Res 2020
Siresha Bathina, Naveen K V Gundala, Poorani Rhenghachar, Sailaja Polavarapu, Anasuya D Hari, Monika Sadananda, Undurti N Das. Arch Med Res 2020
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Lipoxin and Resolvin Receptors Transducing the Resolution of Inflammation in Cardiovascular Disease.
John Pirault, Magnus Bäck. Front Pharmacol 2018
John Pirault, Magnus Bäck. Front Pharmacol 2018
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5-Lipoxygenase, a key enzyme for leukotriene biosynthesis in health and disease.
Olof Rådmark, Oliver Werz, Dieter Steinhilber, Bengt Samuelsson. Biochim Biophys Acta 2015
Olof Rådmark, Oliver Werz, Dieter Steinhilber, Bengt Samuelsson. Biochim Biophys Acta 2015
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Synthesis, biological evaluation, molecular modeling, and structural analysis of new pyrazole and pyrazolone derivatives as N-formyl peptide receptors agonists.
Claudia Vergelli, Andrei I Khlebnikov, Letizia Crocetti, Gabriella Guerrini, Niccolò Cantini, Liliya N Kirpotina, Igor A Schepetkin, Agostino Cilibrizzi, Mark T Quinn, Patrizia Rossi,[...]. Chem Biol Drug Des 2021
Claudia Vergelli, Andrei I Khlebnikov, Letizia Crocetti, Gabriella Guerrini, Niccolò Cantini, Liliya N Kirpotina, Igor A Schepetkin, Agostino Cilibrizzi, Mark T Quinn, Patrizia Rossi,[...]. Chem Biol Drug Des 2021
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Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing.
C N Serhan, C B Clish, J Brannon, S P Colgan, N Chiang, K Gronert. J Exp Med 2000
C N Serhan, C B Clish, J Brannon, S P Colgan, N Chiang, K Gronert. J Exp Med 2000
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Protectins and maresins: New pro-resolving families of mediators in acute inflammation and resolution bioactive metabolome.
Charles N Serhan, Jesmond Dalli, Romain A Colas, Jeremy W Winkler, Nan Chiang. Biochim Biophys Acta 2015
Charles N Serhan, Jesmond Dalli, Romain A Colas, Jeremy W Winkler, Nan Chiang. Biochim Biophys Acta 2015
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Resolution of Inflammation Through the Lipoxin and ALX/FPR2 Receptor Pathway Protects Against Abdominal Aortic Aneurysms.
Marcelo H Petri, Silke Thul, Teodora Andonova, Moritz Lindquist-Liljeqvist, Hong Jin, Nikolaos-Taxiarchis Skenteris, Hildur Arnardottir, Lars Maegdefessel, Kenneth Caidahl, Mauro Perretti,[...]. JACC Basic Transl Sci 2018
Marcelo H Petri, Silke Thul, Teodora Andonova, Moritz Lindquist-Liljeqvist, Hong Jin, Nikolaos-Taxiarchis Skenteris, Hildur Arnardottir, Lars Maegdefessel, Kenneth Caidahl, Mauro Perretti,[...]. JACC Basic Transl Sci 2018
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Discovery and Early Clinical Development of an Inhibitor of 5-Lipoxygenase Activating Protein (AZD5718) for Treatment of Coronary Artery Disease.
Daniel Pettersen, Johan Broddefalk, Hans Emtenäs, Martin A Hayes, Malin Lemurell, Marianne Swanson, Johan Ulander, Carl Whatling, Carl Amilon, Hans Ericsson,[...]. J Med Chem 2019
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Molecular circuits of resolution: formation and actions of resolvins and protectins.
Gerard L Bannenberg, Nan Chiang, Amiram Ariel, Makoto Arita, Eric Tjonahen, Katherine H Gotlinger, Song Hong, Charles N Serhan. J Immunol 2005
Gerard L Bannenberg, Nan Chiang, Amiram Ariel, Makoto Arita, Eric Tjonahen, Katherine H Gotlinger, Song Hong, Charles N Serhan. J Immunol 2005
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High prevalence of COPD in atherosclerosis patients.
Izabela Tuleta, Tarik Farrag, Laura Busse, Carmen Pizarro, Christian Schaefer, Simon Pingel, Georg Nickenig, Dirk Skowasch, Nadjib Schahab. Int J Chron Obstruct Pulmon Dis 2017
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The resolvin D1 analogue controls maturation of dendritic cells and suppresses alloimmunity in corneal transplantation.
Jing Hua, Yiping Jin, Yihe Chen, Takenori Inomata, HyunSoo Lee, Sunil K Chauhan, Nicos A Petasis, Charles N Serhan, Reza Dana. Invest Ophthalmol Vis Sci 2014
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Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators.
Charles N Serhan, Nan Chiang, Thomas E Van Dyke. Nat Rev Immunol 2008
Charles N Serhan, Nan Chiang, Thomas E Van Dyke. Nat Rev Immunol 2008
33
Protectin DX, a double lipoxygenase product of DHA, inhibits both ROS production in human neutrophils and cyclooxygenase activities.
Miao Liu, Tarek Boussetta, Karama Makni-Maalej, Michèle Fay, Fathi Driss, Jamel El-Benna, Michel Lagarde, Michel Guichardant. Lipids 2014
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Phosphorylation by protein kinase a inhibits nuclear import of 5-lipoxygenase.
Ming Luo, Sandra M Jones, Nicolas Flamand, David M Aronoff, Marc Peters-Golden, Thomas G Brock. J Biol Chem 2005
Ming Luo, Sandra M Jones, Nicolas Flamand, David M Aronoff, Marc Peters-Golden, Thomas G Brock. J Biol Chem 2005
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Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: assignments of dihydroxy-containing docosatrienes.
Charles N Serhan, Katherine Gotlinger, Song Hong, Yan Lu, Jeffrey Siegelman, Tamara Baer, Rong Yang, Sean P Colgan, Nicos A Petasis. J Immunol 2006
Charles N Serhan, Katherine Gotlinger, Song Hong, Yan Lu, Jeffrey Siegelman, Tamara Baer, Rong Yang, Sean P Colgan, Nicos A Petasis. J Immunol 2006
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Resolvins and protectins in inflammation resolution.
Charles N Serhan, Nicos A Petasis. Chem Rev 2011
Charles N Serhan, Nicos A Petasis. Chem Rev 2011
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BAY X1005, a new inhibitor of leukotriene synthesis: in vivo inflammation pharmacology and pharmacokinetics.
R Müller-Peddinghaus, C Kohlsdorfer, P Theisen-Popp, R Fruchtmann, E Perzborn, B Beckermann, K Bühner, H J Ahr, K H Mohrs. J Pharmacol Exp Ther 1993
R Müller-Peddinghaus, C Kohlsdorfer, P Theisen-Popp, R Fruchtmann, E Perzborn, B Beckermann, K Bühner, H J Ahr, K H Mohrs. J Pharmacol Exp Ther 1993
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Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions.
Charles N Serhan, Rong Yang, Kimberly Martinod, Kie Kasuga, Padmini S Pillai, Timothy F Porter, Sungwhan F Oh, Matthew Spite. J Exp Med 2009
Charles N Serhan, Rong Yang, Kimberly Martinod, Kie Kasuga, Padmini S Pillai, Timothy F Porter, Sungwhan F Oh, Matthew Spite. J Exp Med 2009
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Stereoselective Synthesis of Maresin-like Lipid Mediators.
Song Hong, Yan Lu, Masao Morita, Shun Saito, Yuichi Kobayashi, Bokkyoo Jun, Nicolas G Bazan, Xiaoming Xu, Yapin Wang. Synlett 2019
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Atherosclerosis Vascular Endothelial Secretion Dysfunction and Smooth Muscle Cell Proliferation.
Junxi Li, Xinying Fu, Renyi Yang, Wei Zhang. J Healthc Eng 2022
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Maresin 1 Mitigates Inflammatory Response and Protects Mice from Sepsis.
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Neuroprotectin D1 (NPD1): a DHA-derived mediator that protects brain and retina against cell injury-induced oxidative stress.
Nicolas G Bazan. Brain Pathol 2005
Nicolas G Bazan. Brain Pathol 2005
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Insights into the Activation Mechanism of the ALX/FPR2 Receptor.
Vinicius Schmitz Nunes, Alexandre P Rogério, Odonírio Abrahão. J Phys Chem Lett 2020
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Experimental modeling of cornea wound healing in diabetes: clinical applications and beyond.
Yashan Bu, Kendrick Co Shih, Sum Sum Kwok, Yau Kei Chan, Amy Cheuk-Yin Lo, Tommy Chung Yan Chan, Vishal Jhanji, Louis Tong. BMJ Open Diabetes Res Care 2019
Yashan Bu, Kendrick Co Shih, Sum Sum Kwok, Yau Kei Chan, Amy Cheuk-Yin Lo, Tommy Chung Yan Chan, Vishal Jhanji, Louis Tong. BMJ Open Diabetes Res Care 2019
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The novel 13S,14S-epoxy-maresin is converted by human macrophages to maresin 1 (MaR1), inhibits leukotriene A4 hydrolase (LTA4H), and shifts macrophage phenotype.
Jesmond Dalli, Min Zhu, Nikita A Vlasenko, Bin Deng, Jesper Z Haeggström, Nicos A Petasis, Charles N Serhan. FASEB J 2013
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The lipoxin receptor ALX: potent ligand-specific and stereoselective actions in vivo.
Nan Chiang, Charles N Serhan, Sven-Erik Dahlén, Jeffrey M Drazen, Douglas W P Hay, G Enrico Rovati, Takao Shimizu, Takehiko Yokomizo, Charles Brink. Pharmacol Rev 2006
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.