Samuel R Witus, Weixing Zhao, Peter S Brzovic, Rachel E Klevit. Trends Biochem Sci 2022
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Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation.
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Impact of amino acid substitutions at secondary structures in the BRCT domains of the tumor suppressor BRCA1: Implications for clinical annotation.
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PTC124 targets genetic disorders caused by nonsense mutations.
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Translational readthrough by the aminoglycoside geneticin (G418) modulates SMN stability in vitro and improves motor function in SMA mice in vivo.
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Readthrough of stop codons by use of aminoglycosides in cells from xeroderma pigmentosum group C patients.
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Restoration of APC gene function in colorectal cancer cells by aminoglycoside- and macrolide-induced read-through of premature termination codons.
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The BRCT Domains of the BRCA1 and BARD1 Tumor Suppressors Differentially Regulate Homology-Directed Repair and Stalled Fork Protection.
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