Alessandro Sette, Shane Crotty. Immunol Rev 2022
Times Cited: 25
Times Cited: 25
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SARS-CoV-2 vaccination induces immunological T cell memory able to cross-recognize variants from Alpha to Omicron.
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T cell responses to SARS-CoV-2 spike cross-recognize Omicron.
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Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection.
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Early induction of functional SARS-CoV-2-specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients.
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mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern.
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Cross-reactive CD4+ T cells enhance SARS-CoV-2 immune responses upon infection and vaccination.
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Ancestral SARS-CoV-2-specific T cells cross-recognize the Omicron variant.
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Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine.
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BNT162b2 vaccination induces durable SARS-CoV-2-specific T cells with a stem cell memory phenotype.
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Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals.
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SARS-CoV-2 mRNA vaccination elicits a robust and persistent T follicular helper cell response in humans.
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Vaccines elicit highly conserved cellular immunity to SARS-CoV-2 Omicron.
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SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls.
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Correlates of protection against SARS-CoV-2 infection and COVID-19 disease.
David Goldblatt, Galit Alter, Shane Crotty, Stanley A Plotkin. Immunol Rev 2022
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SARS-CoV-2 mRNA vaccines induce persistent human germinal centre responses.
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Highly functional virus-specific cellular immune response in asymptomatic SARS-CoV-2 infection.
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Rapid and stable mobilization of CD8+ T cells by SARS-CoV-2 mRNA vaccine.
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Recent endemic coronavirus infection is associated with less-severe COVID-19.
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Low-dose mRNA-1273 COVID-19 vaccine generates durable memory enhanced by cross-reactive T cells.
Jose Mateus, Jennifer M Dan, Zeli Zhang, Carolyn Rydyznski Moderbacher, Marshall Lammers, Benjamin Goodwin, Alessandro Sette, Shane Crotty, Daniela Weiskopf. Science 2021
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Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans.
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Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19.
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Impact of SARS-CoV-2 variants on the total CD4+ and CD8+ T cell reactivity in infected or vaccinated individuals.
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T cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all individuals.
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Longitudinal analysis shows durable and broad immune memory after SARS-CoV-2 infection with persisting antibody responses and memory B and T cells.
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Mechanisms of SARS-CoV-2 entry into cells.
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COVID-19: consider cytokine storm syndromes and immunosuppression.
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Spike-specific circulating T follicular helper cell and cross-neutralizing antibody responses in COVID-19-convalescent individuals.
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SARS-CoV-2 mutations in MHC-I-restricted epitopes evade CD8+ T cell responses.
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Effects of Previous Infection and Vaccination on Symptomatic Omicron Infections.
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Understanding T cell responses to COVID-19 is essential for informing public health strategies.
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Pre-existing polymerase-specific T cells expand in abortive seronegative SARS-CoV-2.
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SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19.
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Clonal analysis of immunodominance and cross-reactivity of the CD4 T cell response to SARS-CoV-2.
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COVID-19 immune signatures reveal stable antiviral T cell function despite declining humoral responses.
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