Wing-Yu Fu, Nancy Y Ip. Semin Cell Dev Biol 2023
Times Cited: 2
Times Cited: 2
Times Cited
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Synapse pathology in Alzheimer's disease.
Jessica Griffiths, Seth G N Grant. Semin Cell Dev Biol 2023
Jessica Griffiths, Seth G N Grant. Semin Cell Dev Biol 2023
100
Presubiculum principal cells are preserved from degeneration in knock-in APP/TAU mouse models of Alzheimer's disease.
Anam Islam, Takashi Saito, Takaomi Saido, Afia B Ali. Semin Cell Dev Biol 2023
Anam Islam, Takashi Saito, Takaomi Saido, Afia B Ali. Semin Cell Dev Biol 2023
50
Novel approaches to increase synaptic resilience as potential treatments for Alzheimer's disease.
Andrew Q Pham, Kim Dore. Semin Cell Dev Biol 2023
Andrew Q Pham, Kim Dore. Semin Cell Dev Biol 2023
100
HEBP1 - An early trigger for neuronal cell death and circuit dysfunction in Alzheimer's disease.
John Jia En Chua. Semin Cell Dev Biol 2023
John Jia En Chua. Semin Cell Dev Biol 2023
100
Inhibition of Nogo-A rescues synaptic plasticity and associativity in APP/PS1 animal model of Alzheimer's disease.
Maria Vazquez Pavon, Sheeja Navakkode, Lik-Wei Wong, Sreedharan Sajikumar. Semin Cell Dev Biol 2023
Maria Vazquez Pavon, Sheeja Navakkode, Lik-Wei Wong, Sreedharan Sajikumar. Semin Cell Dev Biol 2023
50
Pinpointing the locus of GABAergic vulnerability in Alzheimer's disease.
Leire Melgosa-Ecenarro, Nazanin Doostdar, Carola I Radulescu, Johanna S Jackson, Samuel J Barnes. Semin Cell Dev Biol 2023
Leire Melgosa-Ecenarro, Nazanin Doostdar, Carola I Radulescu, Johanna S Jackson, Samuel J Barnes. Semin Cell Dev Biol 2023
100
The therapeutic potential of the neuroactive peptides of soluble amyloid precursor protein-alpha in Alzheimer's disease and related neurological disorders.
Bruce G Mockett, Margaret M Ryan. Semin Cell Dev Biol 2023
Bruce G Mockett, Margaret M Ryan. Semin Cell Dev Biol 2023
100
Revealing cell vulnerability in Alzheimer's disease by single-cell transcriptomics.
Carlos A Saura, Angel Deprada, Maria Dolores Capilla-López, Arnaldo Parra-Damas. Semin Cell Dev Biol 2023
Carlos A Saura, Angel Deprada, Maria Dolores Capilla-López, Arnaldo Parra-Damas. Semin Cell Dev Biol 2023
50
Impairments of glutamatergic synaptic transmission in Alzheimer's disease.
Benedikt Zott, Arthur Konnerth. Semin Cell Dev Biol 2023
Benedikt Zott, Arthur Konnerth. Semin Cell Dev Biol 2023
100
A multimodal RAGE-specific inhibitor reduces amyloid β-mediated brain disorder in a mouse model of Alzheimer disease.
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Rashid Deane, Itender Singh, Abhay P Sagare, Robert D Bell, Nathan T Ross, Barbra LaRue, Rachal Love, Sheldon Perry, Nicole Paquette, Richard J Deane,[...]. J Clin Invest 2012
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Aggregation of vascular risk factors and risk of incident Alzheimer disease.
J A Luchsinger, C Reitz, L S Honig, M X Tang, Steven Shea, R Mayeux. Neurology 2005
J A Luchsinger, C Reitz, L S Honig, M X Tang, Steven Shea, R Mayeux. Neurology 2005
50
Cannabinoids for the treatment of dementia.
Dina Bosnjak Kuharic, Domagoj Markovic, Tonci Brkovic, Milka Jeric Kegalj, Zana Rubic, Ana Vuica Vukasovic, Ana Jeroncic, Livia Puljak. Cochrane Database Syst Rev 2021
Dina Bosnjak Kuharic, Domagoj Markovic, Tonci Brkovic, Milka Jeric Kegalj, Zana Rubic, Ana Vuica Vukasovic, Ana Jeroncic, Livia Puljak. Cochrane Database Syst Rev 2021
50
Donanemab detects a minor fraction of amyloid-β plaques in post-mortem brain tissue of patients with Alzheimer's disease and Down syndrome.
Yvonne Bouter, Hendrik Liekefeld, Steffen Pichlo, Anna Celine Westhoff, Lydia Fenn, Preeti Bakrania, Thomas A Bayer. Acta Neuropathol 2022
Yvonne Bouter, Hendrik Liekefeld, Steffen Pichlo, Anna Celine Westhoff, Lydia Fenn, Preeti Bakrania, Thomas A Bayer. Acta Neuropathol 2022
50
Mitochondria in Alzheimer's disease and their potential role in Alzheimer's proteostasis.
Ian W Weidling, Russell H Swerdlow. Exp Neurol 2020
Ian W Weidling, Russell H Swerdlow. Exp Neurol 2020
50
Omics sciences for systems biology in Alzheimer's disease: State-of-the-art of the evidence.
Harald Hampel, Robert Nisticò, Nicholas T Seyfried, Allan I Levey, Erica Modeste, Pablo Lemercier, Filippo Baldacci, Nicola Toschi, Francesco Garaci, George Perry,[...]. Ageing Res Rev 2021
Harald Hampel, Robert Nisticò, Nicholas T Seyfried, Allan I Levey, Erica Modeste, Pablo Lemercier, Filippo Baldacci, Nicola Toschi, Francesco Garaci, George Perry,[...]. Ageing Res Rev 2021
50
Mitochondrial dysfunctions in neurodegenerative diseases: relevance to Alzheimer's disease.
Jana Hroudová, Namrata Singh, Zdeněk Fišar. Biomed Res Int 2014
Jana Hroudová, Namrata Singh, Zdeněk Fišar. Biomed Res Int 2014
50
Neuropathologic Changes Provide Insights into Key Mechanisms of Alzheimer Disease and Related Dementia.
Germán Plascencia-Villa, George Perry. Am J Pathol 2022
Germán Plascencia-Villa, George Perry. Am J Pathol 2022
50
50
Do glia drive synaptic and cognitive impairment in disease?
Won-Suk Chung, Christina A Welsh, Ben A Barres, Beth Stevens. Nat Neurosci 2015
Won-Suk Chung, Christina A Welsh, Ben A Barres, Beth Stevens. Nat Neurosci 2015
50
Synaptic basis of Alzheimer's disease: Focus on synaptic amyloid beta, P-tau and mitochondria.
Albin John, P Hemachandra Reddy. Ageing Res Rev 2021
Albin John, P Hemachandra Reddy. Ageing Res Rev 2021
50
Solving neurodegeneration: common mechanisms and strategies for new treatments.
Lauren K Wareham, Shane A Liddelow, Sally Temple, Larry I Benowitz, Adriana Di Polo, Cheryl Wellington, Jeffrey L Goldberg, Zhigang He, Xin Duan, Guojun Bu,[...]. Mol Neurodegener 2022
Lauren K Wareham, Shane A Liddelow, Sally Temple, Larry I Benowitz, Adriana Di Polo, Cheryl Wellington, Jeffrey L Goldberg, Zhigang He, Xin Duan, Guojun Bu,[...]. Mol Neurodegener 2022
50
The spirostenol (22R, 25R)-20alpha-spirost-5-en-3beta-yl hexanoate blocks mitochondrial uptake of Abeta in neuronal cells and prevents Abeta-induced impairment of mitochondrial function.
Laurent Tillement, Laurent Lecanu, Wenguo Yao, Janet Greeson, Vassilios Papadopoulos. Steroids 2006
Laurent Tillement, Laurent Lecanu, Wenguo Yao, Janet Greeson, Vassilios Papadopoulos. Steroids 2006
50
Effect of amyloid beta-peptide on permeability transition pore: a comparative study.
Paula I Moreira, Maria S Santos, António Moreno, A Cristina Rego, Catarina Oliveira. J Neurosci Res 2002
Paula I Moreira, Maria S Santos, António Moreno, A Cristina Rego, Catarina Oliveira. J Neurosci Res 2002
50
Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice.
Faith M Harris, Walter J Brecht, Qin Xu, Ina Tesseur, Lisa Kekonius, Tony Wyss-Coray, Jo Dee Fish, Eliezer Masliah, Paul C Hopkins, Kimberly Scearce-Levie,[...]. Proc Natl Acad Sci U S A 2003
Faith M Harris, Walter J Brecht, Qin Xu, Ina Tesseur, Lisa Kekonius, Tony Wyss-Coray, Jo Dee Fish, Eliezer Masliah, Paul C Hopkins, Kimberly Scearce-Levie,[...]. Proc Natl Acad Sci U S A 2003
50
ACU193: An Immunotherapeutic Poised to Test the Amyloid β Oligomer Hypothesis of Alzheimer's Disease.
Grant A Krafft, Jasna Jerecic, Eric Siemers, Erika N Cline. Front Neurosci 2022
Grant A Krafft, Jasna Jerecic, Eric Siemers, Erika N Cline. Front Neurosci 2022
50
Roles of amyloid beta-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer's disease and mild cognitive impairment.
D Allan Butterfield, Tanea Reed, Shelley F Newman, Rukhsana Sultana. Free Radic Biol Med 2007
D Allan Butterfield, Tanea Reed, Shelley F Newman, Rukhsana Sultana. Free Radic Biol Med 2007
50
Proteostasis Failure in Neurodegenerative Diseases: Focus on Oxidative Stress.
Annika Höhn, Antonella Tramutola, Roberta Cascella. Oxid Med Cell Longev 2020
Annika Höhn, Antonella Tramutola, Roberta Cascella. Oxid Med Cell Longev 2020
50
50
Neuropathological stageing of Alzheimer-related changes.
H Braak, E Braak. Acta Neuropathol 1991
H Braak, E Braak. Acta Neuropathol 1991
50
Small molecule therapeutics for tauopathy in Alzheimer's disease: Walking on the path of most resistance.
Lisha Wang, Bharti, Rajnish Kumar, Pavel F Pavlov, Bengt Winblad. Eur J Med Chem 2021
Lisha Wang, Bharti, Rajnish Kumar, Pavel F Pavlov, Bengt Winblad. Eur J Med Chem 2021
50
Human wild-type full-length tau accumulation disrupts mitochondrial dynamics and the functions via increasing mitofusins.
Xia-Chun Li, Yu Hu, Zhi-hao Wang, Yu Luo, Yao Zhang, Xiu-Ping Liu, Qiong Feng, Qun Wang, Keqiang Ye, Gong-Ping Liu,[...]. Sci Rep 2016
Xia-Chun Li, Yu Hu, Zhi-hao Wang, Yu Luo, Yao Zhang, Xiu-Ping Liu, Qiong Feng, Qun Wang, Keqiang Ye, Gong-Ping Liu,[...]. Sci Rep 2016
50
Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease.
Randall J Bateman, Paul S Aisen, Bart De Strooper, Nick C Fox, Cynthia A Lemere, John M Ringman, Stephen Salloway, Reisa A Sperling, Manfred Windisch, Chengjie Xiong. Alzheimers Res Ther 2011
Randall J Bateman, Paul S Aisen, Bart De Strooper, Nick C Fox, Cynthia A Lemere, John M Ringman, Stephen Salloway, Reisa A Sperling, Manfred Windisch, Chengjie Xiong. Alzheimers Res Ther 2011
50
Emerging Pathophysiological Mechanisms Linking Diabetes Mellitus and Alzheimer's Disease: An Old Wine in a New Bottle.
Vishvas N Patel, Mehul R Chorawala, Maitri B Shah, Kashvi C Shah, Bhavarth P Dave, Manal P Shah, Tanvi M Patel. J Alzheimers Dis Rep 2022
Vishvas N Patel, Mehul R Chorawala, Maitri B Shah, Kashvi C Shah, Bhavarth P Dave, Manal P Shah, Tanvi M Patel. J Alzheimers Dis Rep 2022
50
Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia.
Eric M Reiman, Kewei Chen, Gene E Alexander, Richard J Caselli, Daniel Bandy, David Osborne, Ann M Saunders, John Hardy. Proc Natl Acad Sci U S A 2004
Eric M Reiman, Kewei Chen, Gene E Alexander, Richard J Caselli, Daniel Bandy, David Osborne, Ann M Saunders, John Hardy. Proc Natl Acad Sci U S A 2004
50
Noradrenergic Add-on Therapy with Extended-Release Guanfacine in Alzheimer's Disease (NorAD): study protocol for a randomised clinical trial and COVID-19 amendments.
Karen Hoang, Hilary Watt, Mara Golemme, Richard J Perry, Craig Ritchie, Danielle Wilson, James Pickett, Chris Fox, Robert Howard, Paresh A Malhotra. Trials 2022
Karen Hoang, Hilary Watt, Mara Golemme, Richard J Perry, Craig Ritchie, Danielle Wilson, James Pickett, Chris Fox, Robert Howard, Paresh A Malhotra. Trials 2022
50
Plasma biomarkers of Alzheimer's disease improve prediction of cognitive decline in cognitively unimpaired elderly populations.
Nicholas C Cullen, Antoine Leuzy, Shorena Janelidze, Sebastian Palmqvist, Anna L Svenningsson, Erik Stomrud, Jeffrey L Dage, Niklas Mattsson-Carlgren, Oskar Hansson. Nat Commun 2021
Nicholas C Cullen, Antoine Leuzy, Shorena Janelidze, Sebastian Palmqvist, Anna L Svenningsson, Erik Stomrud, Jeffrey L Dage, Niklas Mattsson-Carlgren, Oskar Hansson. Nat Commun 2021
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Amyloid β oligomers in Alzheimer's disease pathogenesis, treatment, and diagnosis.
Kirsten L Viola, William L Klein. Acta Neuropathol 2015
Kirsten L Viola, William L Klein. Acta Neuropathol 2015
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A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers.
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Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
Iris E Jansen, Jeanne E Savage, Kyoko Watanabe, Julien Bryois, Dylan M Williams, Stacy Steinberg, Julia Sealock, Ida K Karlsson, Sara Hägg, Lavinia Athanasiu,[...]. Nat Genet 2019
Iris E Jansen, Jeanne E Savage, Kyoko Watanabe, Julien Bryois, Dylan M Williams, Stacy Steinberg, Julia Sealock, Ida K Karlsson, Sara Hägg, Lavinia Athanasiu,[...]. Nat Genet 2019
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Linking Abeta and tau in late-onset Alzheimer's disease: a dual pathway hypothesis.
Scott A Small, Karen Duff. Neuron 2008
Scott A Small, Karen Duff. Neuron 2008
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Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study.
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Victor L Villemagne, Samantha Burnham, Pierrick Bourgeat, Belinda Brown, Kathryn A Ellis, Olivier Salvado, Cassandra Szoeke, S Lance Macaulay, Ralph Martins, Paul Maruff,[...]. Lancet Neurol 2013
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The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae.
Camilla A Hansson Petersen, Nyosha Alikhani, Homira Behbahani, Birgitta Wiehager, Pavel F Pavlov, Irina Alafuzoff, Ville Leinonen, Akira Ito, Bengt Winblad, Elzbieta Glaser,[...]. Proc Natl Acad Sci U S A 2008
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High performance plasma amyloid-β biomarkers for Alzheimer's disease.
Akinori Nakamura, Naoki Kaneko, Victor L Villemagne, Takashi Kato, James Doecke, Vincent Doré, Chris Fowler, Qiao-Xin Li, Ralph Martins, Christopher Rowe,[...]. Nature 2018
Akinori Nakamura, Naoki Kaneko, Victor L Villemagne, Takashi Kato, James Doecke, Vincent Doré, Chris Fowler, Qiao-Xin Li, Ralph Martins, Christopher Rowe,[...]. Nature 2018
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PET amyloid-beta imaging in preclinical Alzheimer's disease.
Andrei G Vlassenko, Tammie L S Benzinger, John C Morris. Biochim Biophys Acta 2012
Andrei G Vlassenko, Tammie L S Benzinger, John C Morris. Biochim Biophys Acta 2012
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Multi-functional drugs for various CNS targets in the treatment of neurodegenerative disorders.
Moussa B H Youdim, Jerry J Buccafusco. Trends Pharmacol Sci 2005
Moussa B H Youdim, Jerry J Buccafusco. Trends Pharmacol Sci 2005
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How neurons die in Alzheimer's disease: Implications for neuroinflammation.
Aman Mangalmurti, John R Lukens. Curr Opin Neurobiol 2022
Aman Mangalmurti, John R Lukens. Curr Opin Neurobiol 2022
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Genetics of dementia.
Clement T Loy, Peter R Schofield, Anne M Turner, John B J Kwok. Lancet 2014
Clement T Loy, Peter R Schofield, Anne M Turner, John B J Kwok. Lancet 2014
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Contribution to Alzheimer's disease risk of rare variants in TREM2, SORL1, and ABCA7 in 1779 cases and 1273 controls.
Céline Bellenguez, Camille Charbonnier, Benjamin Grenier-Boley, Olivier Quenez, Kilan Le Guennec, Gaël Nicolas, Ganesh Chauhan, David Wallon, Stéphane Rousseau, Anne Claire Richard,[...]. Neurobiol Aging 2017
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The Role of Exosomes as Mediators of Neuroinflammation in the Pathogenesis and Treatment of Alzheimer's Disease.
Shiting Weng, Qi-Lun Lai, Junjun Wang, Liying Zhuang, Lin Cheng, Yejia Mo, Lu Liu, Zexian Zhao, Ying Zhang, Song Qiao. Front Aging Neurosci 2022
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