D V Reynolds. Science 1969
Times Cited: 936
Times Cited: 936
Times Cited
Times Co-cited
Similarity
Pain relief by electrical stimulation of the central gray matter in humans and its reversal by naloxone.
Y Hosobuchi, J E Adams, R Linchitz. Science 1977
Y Hosobuchi, J E Adams, R Linchitz. Science 1977
21
Descending control of nociception: Specificity, recruitment and plasticity.
M M Heinricher, I Tavares, J L Leith, B M Lumb. Brain Res Rev 2009
M M Heinricher, I Tavares, J L Leith, B M Lumb. Brain Res Rev 2009
20
Endogenous pain control systems: brainstem spinal pathways and endorphin circuitry.
A I Basbaum, H L Fields. Annu Rev Neurosci 1984
A I Basbaum, H L Fields. Annu Rev Neurosci 1984
17
Analgesia from electrical stimulation in the brainstem of the rat.
D J Mayer, T L Wolfle, H Akil, B Carder, J C Liebeskind. Science 1971
D J Mayer, T L Wolfle, H Akil, B Carder, J C Liebeskind. Science 1971
15
Pain reduction by electrical brain stimulation in man. Part 1: Acute administration in periaqueductal and periventricular sites.
D E Richardson, H Akil. J Neurosurg 1977
D E Richardson, H Akil. J Neurosurg 1977
15
15
Evidence that an excitatory connection between the periaqueductal gray and nucleus raphe magnus mediates stimulation produced analgesia.
M M Behbehani, H L Fields. Brain Res 1979
M M Behbehani, H L Fields. Brain Res 1979
14
Midbrain circuits for defensive behaviour.
Philip Tovote, Maria Soledad Esposito, Paolo Botta, Fabrice Chaudun, Jonathan P Fadok, Milica Markovic, Steffen B E Wolff, Charu Ramakrishnan, Lief Fenno, Karl Deisseroth,[...]. Nature 2016
Philip Tovote, Maria Soledad Esposito, Paolo Botta, Fabrice Chaudun, Jonathan P Fadok, Milica Markovic, Steffen B E Wolff, Charu Ramakrishnan, Lief Fenno, Karl Deisseroth,[...]. Nature 2016
13
Evidence for GABA involvement in midbrain control of medullary neurons that modulate nociceptive transmission.
J L Moreau, H L Fields. Brain Res 1986
J L Moreau, H L Fields. Brain Res 1986
11
11
11
Columnar organization in the midbrain periaqueductal gray: modules for emotional expression?
R Bandler, M T Shipley. Trends Neurosci 1994
R Bandler, M T Shipley. Trends Neurosci 1994
10
Neuroimaging of the periaqueductal gray: state of the field.
Clas Linnman, Eric A Moulton, Gabi Barmettler, Lino Becerra, David Borsook. Neuroimage 2012
Clas Linnman, Eric A Moulton, Gabi Barmettler, Lino Becerra, David Borsook. Neuroimage 2012
9
Descending modulation of pain: the GABA disinhibition hypothesis of analgesia.
Benjamin K Lau, Christopher W Vaughan. Curr Opin Neurobiol 2014
Benjamin K Lau, Christopher W Vaughan. Curr Opin Neurobiol 2014
9
Long term results of periventricular gray self-stimulation.
D E Richardson, H Akil. Neurosurgery 1977
D E Richardson, H Akil. Neurosurgery 1977
12
Descending pain modulation and chronification of pain.
Michael H Ossipov, Kozo Morimura, Frank Porreca. Curr Opin Support Palliat Care 2014
Michael H Ossipov, Kozo Morimura, Frank Porreca. Curr Opin Support Palliat Care 2014
8
Pain reduction by focal electrical stimulation of the brain: an anatomical and behavioral analysis.
D J Mayer, J C Liebeskind. Brain Res 1974
D J Mayer, J C Liebeskind. Brain Res 1974
8
Analgesia from electrical stimulation of the periaqueductal gray matter in the cat: behavioral observations and inhibitory effects on spinal cord interneurons.
J C Liebeskind, G Guilbaud, J M Besson, J L Oliveras. Brain Res 1973
J C Liebeskind, G Guilbaud, J M Besson, J L Oliveras. Brain Res 1973
8
Corticostriatal functional connectivity predicts transition to chronic back pain.
Marwan N Baliki, Bogdan Petre, Souraya Torbey, Kristina M Herrmann, Lejian Huang, Thomas J Schnitzer, Howard L Fields, A Vania Apkarian. Nat Neurosci 2012
Marwan N Baliki, Bogdan Petre, Souraya Torbey, Kristina M Herrmann, Lejian Huang, Thomas J Schnitzer, Howard L Fields, A Vania Apkarian. Nat Neurosci 2012
8
Antagonism of stimulation-produced analgesia by naloxone, a narcotic antagonist.
H Akil, D J Mayer, J C Liebeskind. Science 1976
H Akil, D J Mayer, J C Liebeskind. Science 1976
8
The periaqueductal gray and defensive behavior: functional representation and neuronal organization.
P Carrive. Behav Brain Res 1993
P Carrive. Behav Brain Res 1993
8
The cerebral signature for pain perception and its modulation.
Irene Tracey, Patrick W Mantyh. Neuron 2007
Irene Tracey, Patrick W Mantyh. Neuron 2007
8
Divergent Modulation of Nociception by Glutamatergic and GABAergic Neuronal Subpopulations in the Periaqueductal Gray.
Vijay K Samineni, Jose G Grajales-Reyes, Bryan A Copits, Daniel E O'Brien, Sarah L Trigg, Adrian M Gomez, Michael R Bruchas, Robert W Gereau. eNeuro 2017
Vijay K Samineni, Jose G Grajales-Reyes, Bryan A Copits, Daniel E O'Brien, Sarah L Trigg, Adrian M Gomez, Michael R Bruchas, Robert W Gereau. eNeuro 2017
13
T-type channels control the opioidergic descending analgesia at the low threshold-spiking GABAergic neurons in the periaqueductal gray.
Cheongdahm Park, Jong-Hyun Kim, Bo-Eun Yoon, Eui-Ju Choi, C Justin Lee, Hee-Sup Shin. Proc Natl Acad Sci U S A 2010
Cheongdahm Park, Jong-Hyun Kim, Bo-Eun Yoon, Eui-Ju Choi, C Justin Lee, Hee-Sup Shin. Proc Natl Acad Sci U S A 2010
15
The effect of GABA and its antagonists on midbrain periaqueductal gray neurons in the rat.
Michael M Behbehani, Maorong Jiang, Sharon D Chandler, Matthew Ennis. Pain 1990
Michael M Behbehani, Maorong Jiang, Sharon D Chandler, Matthew Ennis. Pain 1990
7
An endocannabinoid mechanism for stress-induced analgesia.
Andrea G Hohmann, Richard L Suplita, Nathan M Bolton, Mark H Neely, Darren Fegley, Regina Mangieri, Jocelyn F Krey, J Michael Walker, Philip V Holmes, Jonathon D Crystal,[...]. Nature 2005
Andrea G Hohmann, Richard L Suplita, Nathan M Bolton, Mark H Neely, Darren Fegley, Regina Mangieri, Jocelyn F Krey, J Michael Walker, Philip V Holmes, Jonathon D Crystal,[...]. Nature 2005
7
Long-term outcomes of deep brain stimulation for neuropathic pain.
Sandra G J Boccard, Erlick A C Pereira, Liz Moir, Tipu Z Aziz, Alexander L Green. Neurosurgery 2013
Sandra G J Boccard, Erlick A C Pereira, Liz Moir, Tipu Z Aziz, Alexander L Green. Neurosurgery 2013
7
Targeting the affective component of chronic pain: a case series of deep brain stimulation of the anterior cingulate cortex.
Sandra G J Boccard, James J Fitzgerald, Erlick A C Pereira, Liz Moir, Tim J Van Hartevelt, Morten L Kringelbach, Alexander L Green, Tipu Z Aziz. Neurosurgery 2014
Sandra G J Boccard, James J Fitzgerald, Erlick A C Pereira, Liz Moir, Tim J Van Hartevelt, Morten L Kringelbach, Alexander L Green, Tipu Z Aziz. Neurosurgery 2014
10
Nucleus raphe magnus inhibition of spinal cord dorsal horn neurons.
H L Fields, A I Basbaum, C H Clanton, S D Anderson. Brain Res 1977
H L Fields, A I Basbaum, C H Clanton, S D Anderson. Brain Res 1977
7
Inhibitory effects evoked from both the lateral and ventrolateral periaqueductal grey are selective for the nociceptive responses of rat dorsal horn neurones.
A J Waters, B M Lumb. Brain Res 1997
A J Waters, B M Lumb. Brain Res 1997
16
Pain reduction by electrical brain stimulation in man. Part 2: Chronic self-administration in the periventricular gray matter.
D E Richardson, H Akil. J Neurosurg 1977
D E Richardson, H Akil. J Neurosurg 1977
7
Pain pathways and parabrachial circuits in the rat.
Caroline Gauriau, Jean-François Bernard. Exp Physiol 2002
Caroline Gauriau, Jean-François Bernard. Exp Physiol 2002
7
The origin of descending pathways in the dorsolateral funiculus of the spinal cord of the cat and rat: further studies on the anatomy of pain modulation.
A I Basbaum, H L Fields. J Comp Neurol 1979
A I Basbaum, H L Fields. J Comp Neurol 1979
7
7
Engagement of descending inhibition from the rostral ventromedial medulla protects against chronic neuropathic pain.
Milena De Felice, Raul Sanoja, Ruizhong Wang, Louis Vera-Portocarrero, Janice Oyarzo, Tamara King, Michael H Ossipov, Todd W Vanderah, Josephine Lai, Gregory O Dussor,[...]. Pain 2011
Milena De Felice, Raul Sanoja, Ruizhong Wang, Louis Vera-Portocarrero, Janice Oyarzo, Tamara King, Michael H Ossipov, Todd W Vanderah, Josephine Lai, Gregory O Dussor,[...]. Pain 2011
7
Concurrent mapping of brain sites for sensitivity to the direct application of morphine and focal electrical stimulation in the production of antinociception in the rat.
Joseph C Yeung, Tony L Yaksh, Thomas A Rudy. Pain 1977
Joseph C Yeung, Tony L Yaksh, Thomas A Rudy. Pain 1977
7
How opioids inhibit GABA-mediated neurotransmission.
C W Vaughan, S L Ingram, M A Connor, M J Christie. Nature 1997
C W Vaughan, S L Ingram, M A Connor, M J Christie. Nature 1997
7
Pain relief produces negative reinforcement through activation of mesolimbic reward-valuation circuitry.
Edita Navratilova, Jennifer Y Xie, Alec Okun, Chaoling Qu, Nathan Eyde, Shuang Ci, Michael H Ossipov, Tamara King, Howard L Fields, Frank Porreca. Proc Natl Acad Sci U S A 2012
Edita Navratilova, Jennifer Y Xie, Alec Okun, Chaoling Qu, Nathan Eyde, Shuang Ci, Michael H Ossipov, Tamara King, Howard L Fields, Frank Porreca. Proc Natl Acad Sci U S A 2012
6
Periaqueductal gray neurons project to spinally projecting GABAergic neurons in the rostral ventromedial medulla.
Michael M Morgan, Kelsey L Whittier, Deborah M Hegarty, Sue A Aicher. Pain 2008
Michael M Morgan, Kelsey L Whittier, Deborah M Hegarty, Sue A Aicher. Pain 2008
6
Autopsy analysis of the safety, efficacy and cartography of electrical stimulation of the central gray in humans.
D S Baskin, W R Mehler, Y Hosobuchi, D E Richardson, J E Adams, M A Flitter. Brain Res 1986
D S Baskin, W R Mehler, Y Hosobuchi, D E Richardson, J E Adams, M A Flitter. Brain Res 1986
9
Activation of the opioidergic descending pain control system underlies placebo analgesia.
Falk Eippert, Ulrike Bingel, Eszter D Schoell, Juliana Yacubian, Regine Klinger, Jürgen Lorenz, Christian Büchel. Neuron 2009
Falk Eippert, Ulrike Bingel, Eszter D Schoell, Juliana Yacubian, Regine Klinger, Jürgen Lorenz, Christian Büchel. Neuron 2009
6
Neurotransmitters in nociceptive modulatory circuits.
H L Fields, M M Heinricher, P Mason. Annu Rev Neurosci 1991
H L Fields, M M Heinricher, P Mason. Annu Rev Neurosci 1991
6
STUDIES ON THE SITE OF ANALGESIC ACTION OF MORPHINE BY INTRACEREBRAL MICRO-INJECTION.
K TSOU, C S JANG. Sci Sin 1964
K TSOU, C S JANG. Sci Sin 1964
6
Mu Opioid Receptor Modulation of Dopamine Neurons in the Periaqueductal Gray/Dorsal Raphe: A Role in Regulation of Pain.
Chia Li, Jonathan A Sugam, Emily G Lowery-Gionta, Zoe A McElligott, Nora M McCall, Alberto J Lopez, Jessica M McKlveen, Kristen E Pleil, Thomas L Kash. Neuropsychopharmacology 2016
Chia Li, Jonathan A Sugam, Emily G Lowery-Gionta, Zoe A McElligott, Nora M McCall, Alberto J Lopez, Jessica M McKlveen, Kristen E Pleil, Thomas L Kash. Neuropsychopharmacology 2016
8
Sex differences in micro-opioid receptor expression in the rat midbrain periaqueductal gray are essential for eliciting sex differences in morphine analgesia.
Dayna R Loyd, Xioaya Wang, Anne Z Murphy. J Neurosci 2008
Dayna R Loyd, Xioaya Wang, Anne Z Murphy. J Neurosci 2008
6
Deep brain stimulation for chronic pain: results of two multicenter trials and a structured review.
R J Coffey. Pain Med 2001
R J Coffey. Pain Med 2001
6
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.