D J Cosens, A Manning. Nature 1969
Times Cited: 386
Times Cited: 386
Times Cited
Times Co-cited
Similarity
Molecular characterization of the Drosophila trp locus: a putative integral membrane protein required for phototransduction.
C Montell, G M Rubin. Neuron 1989
C Montell, G M Rubin. Neuron 1989
46
The capsaicin receptor: a heat-activated ion channel in the pain pathway.
M J Caterina, M A Schumacher, M Tominaga, T A Rosen, J D Levine, D Julius. Nature 1997
M J Caterina, M A Schumacher, M Tominaga, T A Rosen, J D Levine, D Julius. Nature 1997
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TRPC1, a human homolog of a Drosophila store-operated channel.
P D Wes, J Chevesich, A Jeromin, C Rosenberg, G Stetten, C Montell. Proc Natl Acad Sci U S A 1995
P D Wes, J Chevesich, A Jeromin, C Rosenberg, G Stetten, C Montell. Proc Natl Acad Sci U S A 1995
31
Structure of the TRPV1 ion channel determined by electron cryo-microscopy.
Maofu Liao, Erhu Cao, David Julius, Yifan Cheng. Nature 2013
Maofu Liao, Erhu Cao, David Julius, Yifan Cheng. Nature 2013
24
ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures.
Gina M Story, Andrea M Peier, Alison J Reeve, Samer R Eid, Johannes Mosbacher, Todd R Hricik, Taryn J Earley, Anne C Hergarden, David A Andersson, Sun Wook Hwang,[...]. Cell 2003
Gina M Story, Andrea M Peier, Alison J Reeve, Samer R Eid, Johannes Mosbacher, Todd R Hricik, Taryn J Earley, Anne C Hergarden, David A Andersson, Sun Wook Hwang,[...]. Cell 2003
24
The trp gene is essential for a light-activated Ca2+ channel in Drosophila photoreceptors.
R C Hardie, B Minke. Neuron 1992
R C Hardie, B Minke. Neuron 1992
22
An introduction to TRP channels.
I Scott Ramsey, Markus Delling, David E Clapham. Annu Rev Physiol 2006
I Scott Ramsey, Markus Delling, David E Clapham. Annu Rev Physiol 2006
21
The transient receptor potential family of ion channels.
Bernd Nilius, Grzegorz Owsianik. Genome Biol 2011
Bernd Nilius, Grzegorz Owsianik. Genome Biol 2011
20
Molecular cloning of a widely expressed human homologue for the Drosophila trp gene.
X Zhu, P B Chu, M Peyton, L Birnbaumer. FEBS Lett 1995
X Zhu, P B Chu, M Peyton, L Birnbaumer. FEBS Lett 1995
19
TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents.
Diana M Bautista, Sven-Eric Jordt, Tetsuro Nikai, Pamela R Tsuruda, Andrew J Read, Jeannie Poblete, Ebenezer N Yamoah, Allan I Basbaum, David Julius. Cell 2006
Diana M Bautista, Sven-Eric Jordt, Tetsuro Nikai, Pamela R Tsuruda, Andrew J Read, Jeannie Poblete, Ebenezer N Yamoah, Allan I Basbaum, David Julius. Cell 2006
18
Impaired nociception and pain sensation in mice lacking the capsaicin receptor.
M J Caterina, A Leffler, A B Malmberg, W J Martin, J Trafton, K R Petersen-Zeitz, M Koltzenburg, A I Basbaum, D Julius. Science 2000
M J Caterina, A Leffler, A B Malmberg, W J Martin, J Trafton, K R Petersen-Zeitz, M Koltzenburg, A I Basbaum, D Julius. Science 2000
18
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1.
Sven-Eric Jordt, Diana M Bautista, Huai-Hu Chuang, David D McKemy, Peter M Zygmunt, Edward D Högestätt, Ian D Meng, David Julius. Nature 2004
Sven-Eric Jordt, Diana M Bautista, Huai-Hu Chuang, David D McKemy, Peter M Zygmunt, Edward D Högestätt, Ian D Meng, David Julius. Nature 2004
17
TRPV1 structures in distinct conformations reveal activation mechanisms.
Erhu Cao, Maofu Liao, Yifan Cheng, David Julius. Nature 2013
Erhu Cao, Maofu Liao, Yifan Cheng, David Julius. Nature 2013
17
Transient receptor potential cation channels in disease.
Bernd Nilius, Grzegorz Owsianik, Thomas Voets, John A Peters. Physiol Rev 2007
Bernd Nilius, Grzegorz Owsianik, Thomas Voets, John A Peters. Physiol Rev 2007
17
TRP channel activation by reversible covalent modification.
Andrew Hinman, Huai-Hu Chuang, Diana M Bautista, David Julius. Proc Natl Acad Sci U S A 2006
Andrew Hinman, Huai-Hu Chuang, Diana M Bautista, David Julius. Proc Natl Acad Sci U S A 2006
17
Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor.
W Liedtke, Y Choe, M A Martí-Renom, A M Bell, C S Denis, A Sali, A J Hudspeth, J M Friedman, S Heller. Cell 2000
W Liedtke, Y Choe, M A Martí-Renom, A M Bell, C S Denis, A Sali, A J Hudspeth, J M Friedman, S Heller. Cell 2000
16
ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology.
A L Perraud, A Fleig, C A Dunn, L A Bagley, P Launay, C Schmitz, A J Stokes, Q Zhu, M J Bessman, R Penner,[...]. Nature 2001
A L Perraud, A Fleig, C A Dunn, L A Bagley, P Launay, C Schmitz, A J Stokes, Q Zhu, M J Bessman, R Penner,[...]. Nature 2001
15
TRPA1 mediates formalin-induced pain.
Colleen R McNamara, Josh Mandel-Brehm, Diana M Bautista, Jan Siemens, Kari L Deranian, Michael Zhao, Neil J Hayward, Jayhong A Chong, David Julius, Magdalene M Moran,[...]. Proc Natl Acad Sci U S A 2007
Colleen R McNamara, Josh Mandel-Brehm, Diana M Bautista, Jan Siemens, Kari L Deranian, Michael Zhao, Neil J Hayward, Jayhong A Chong, David Julius, Magdalene M Moran,[...]. Proc Natl Acad Sci U S A 2007
15
Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin.
Michael Bandell, Gina M Story, Sun Wook Hwang, Veena Viswanath, Samer R Eid, Matt J Petrus, Taryn J Earley, Ardem Patapoutian. Neuron 2004
Michael Bandell, Gina M Story, Sun Wook Hwang, Veena Viswanath, Samer R Eid, Matt J Petrus, Taryn J Earley, Ardem Patapoutian. Neuron 2004
15
A TRP channel trio mediates acute noxious heat sensing.
Ine Vandewauw, Katrien De Clercq, Marie Mulier, Katharina Held, Silvia Pinto, Nele Van Ranst, Andrei Segal, Thierry Voet, Rudi Vennekens, Katharina Zimmermann,[...]. Nature 2018
Ine Vandewauw, Katrien De Clercq, Marie Mulier, Katharina Held, Silvia Pinto, Nele Van Ranst, Andrei Segal, Thierry Voet, Rudi Vennekens, Katharina Zimmermann,[...]. Nature 2018
15
Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia.
J B Davis, J Gray, M J Gunthorpe, J P Hatcher, P T Davey, P Overend, M H Harries, J Latcham, C Clapham, K Atkinson,[...]. Nature 2000
J B Davis, J Gray, M J Gunthorpe, J P Hatcher, P T Davey, P Overend, M H Harries, J Latcham, C Clapham, K Atkinson,[...]. Nature 2000
14
Identification of a cold receptor reveals a general role for TRP channels in thermosensation.
David D McKemy, Werner M Neuhausser, David Julius. Nature 2002
David D McKemy, Werner M Neuhausser, David Julius. Nature 2002
14
A capsaicin-receptor homologue with a high threshold for noxious heat.
M J Caterina, T A Rosen, M Tominaga, A J Brake, D Julius. Nature 1999
M J Caterina, T A Rosen, M Tominaga, A J Brake, D Julius. Nature 1999
14
Cryo-electron microscopy structure of the TRPV2 ion channel.
Lejla Zubcevic, Mark A Herzik, Ben C Chung, Zhirui Liu, Gabriel C Lander, Seok-Yong Lee. Nat Struct Mol Biol 2016
Lejla Zubcevic, Mark A Herzik, Ben C Chung, Zhirui Liu, Gabriel C Lander, Seok-Yong Lee. Nat Struct Mol Biol 2016
14
Induction of photoreceptor voltage noise in the dark in Drosophila mutant.
B Minke, C Wu, W L Pak. Nature 1975
B Minke, C Wu, W L Pak. Nature 1975
14
Transient receptor potential A1 is a sensory receptor for multiple products of oxidative stress.
David A Andersson, Clive Gentry, Sian Moss, Stuart Bevan. J Neurosci 2008
David A Andersson, Clive Gentry, Sian Moss, Stuart Bevan. J Neurosci 2008
13
Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol.
T Hofmann, A G Obukhov, M Schaefer, C Harteneck, T Gudermann, G Schultz. Nature 1999
T Hofmann, A G Obukhov, M Schaefer, C Harteneck, T Gudermann, G Schultz. Nature 1999
13
Identification of a Drosophila gene encoding a calmodulin-binding protein with homology to the trp phototransduction gene.
A M Phillips, A Bull, L E Kelly. Neuron 1992
A M Phillips, A Bull, L E Kelly. Neuron 1992
13
Transient receptor potential channels as drug targets: from the science of basic research to the art of medicine.
Bernd Nilius, Arpad Szallasi. Pharmacol Rev 2014
Bernd Nilius, Arpad Szallasi. Pharmacol Rev 2014
13
Structure of the mouse TRPC4 ion channel.
Jingjing Duan, Jian Li, Bo Zeng, Gui-Lan Chen, Xiaogang Peng, Yixing Zhang, Jianbin Wang, David E Clapham, Zongli Li, Jin Zhang. Nat Commun 2018
Jingjing Duan, Jian Li, Bo Zeng, Gui-Lan Chen, Xiaogang Peng, Yixing Zhang, Jianbin Wang, David E Clapham, Zongli Li, Jin Zhang. Nat Commun 2018
19
The TRP channels, a remarkably functional family.
Craig Montell, Lutz Birnbaumer, Veit Flockerzi. Cell 2002
Craig Montell, Lutz Birnbaumer, Veit Flockerzi. Cell 2002
12
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action.
Yuan Gao, Erhu Cao, David Julius, Yifan Cheng. Nature 2016
Yuan Gao, Erhu Cao, David Julius, Yifan Cheng. Nature 2016
12
OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity.
R Strotmann, C Harteneck, K Nunnenmacher, G Schultz, T D Plant. Nat Cell Biol 2000
R Strotmann, C Harteneck, K Nunnenmacher, G Schultz, T D Plant. Nat Cell Biol 2000
12
Structure of the TRPA1 ion channel suggests regulatory mechanisms.
Candice E Paulsen, Jean-Paul Armache, Yuan Gao, Yifan Cheng, David Julius. Nature 2015
Candice E Paulsen, Jean-Paul Armache, Yuan Gao, Yifan Cheng, David Julius. Nature 2015
12
Structure of the receptor-activated human TRPC6 and TRPC3 ion channels.
Qinglin Tang, Wenjun Guo, Li Zheng, Jing-Xiang Wu, Meng Liu, Xindi Zhou, Xiaolin Zhang, Lei Chen. Cell Res 2018
Qinglin Tang, Wenjun Guo, Li Zheng, Jing-Xiang Wu, Meng Liu, Xindi Zhou, Xiaolin Zhang, Lei Chen. Cell Res 2018
14
Regulation of canonical transient receptor potential (TRPC) channel function by diacylglycerol and protein kinase C.
Kartik Venkatachalam, Fei Zheng, Donald L Gill. J Biol Chem 2003
Kartik Venkatachalam, Fei Zheng, Donald L Gill. J Biol Chem 2003
11
Heat-evoked activation of TRPV4 channels in a HEK293 cell expression system and in native mouse aorta endothelial cells.
Hiroyuki Watanabe, Joris Vriens, Suk H Suh, Christopher D Benham, Guy Droogmans, Bernd Nilius. J Biol Chem 2002
Hiroyuki Watanabe, Joris Vriens, Suk H Suh, Christopher D Benham, Guy Droogmans, Bernd Nilius. J Biol Chem 2002
11
Heat-evoked activation of the ion channel, TRPV4.
Ali Deniz Güler, Hyosang Lee, Tohko Iida, Isao Shimizu, Makoto Tominaga, Michael Caterina. J Neurosci 2002
Ali Deniz Güler, Hyosang Lee, Tohko Iida, Isao Shimizu, Makoto Tominaga, Michael Caterina. J Neurosci 2002
11
Crystal structure of the epithelial calcium channel TRPV6.
Kei Saotome, Appu K Singh, Maria V Yelshanskaya, Alexander I Sobolevsky. Nature 2016
Kei Saotome, Appu K Singh, Maria V Yelshanskaya, Alexander I Sobolevsky. Nature 2016
11
Structure of the full-length TRPV2 channel by cryo-EM.
Kevin W Huynh, Matthew R Cohen, Jiansen Jiang, Amrita Samanta, David T Lodowski, Z Hong Zhou, Vera Y Moiseenkova-Bell. Nat Commun 2016
Kevin W Huynh, Matthew R Cohen, Jiansen Jiang, Amrita Samanta, David T Lodowski, Z Hong Zhou, Vera Y Moiseenkova-Bell. Nat Commun 2016
11
TRPC1 and TRPC5 form a novel cation channel in mammalian brain.
C Strübing, G Krapivinsky, L Krapivinsky, D E Clapham. Neuron 2001
C Strübing, G Krapivinsky, L Krapivinsky, D E Clapham. Neuron 2001
11
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1.
Marcello Trevisani, Jan Siemens, Serena Materazzi, Diana M Bautista, Romina Nassini, Barbara Campi, Noritaka Imamachi, Eunice Andrè, Riccardo Patacchini, Graeme S Cottrell,[...]. Proc Natl Acad Sci U S A 2007
Marcello Trevisani, Jan Siemens, Serena Materazzi, Diana M Bautista, Romina Nassini, Barbara Campi, Noritaka Imamachi, Eunice Andrè, Riccardo Patacchini, Graeme S Cottrell,[...]. Proc Natl Acad Sci U S A 2007
11
TRPV3 is a calcium-permeable temperature-sensitive cation channel.
Haoxing Xu, I Scott Ramsey, Suhas A Kotecha, Magdalene M Moran, Jayhong A Chong, Deborah Lawson, Pei Ge, Jeremiah Lilly, Inmaculada Silos-Santiago, Yu Xie,[...]. Nature 2002
Haoxing Xu, I Scott Ramsey, Suhas A Kotecha, Magdalene M Moran, Jayhong A Chong, Deborah Lawson, Pei Ge, Jeremiah Lilly, Inmaculada Silos-Santiago, Yu Xie,[...]. Nature 2002
10
TRPV3 is a temperature-sensitive vanilloid receptor-like protein.
G D Smith, M J Gunthorpe, R E Kelsell, P D Hayes, P Reilly, P Facer, J E Wright, J C Jerman, J-P Walhin, L Ooi,[...]. Nature 2002
G D Smith, M J Gunthorpe, R E Kelsell, P D Hayes, P Reilly, P Facer, J E Wright, J C Jerman, J-P Walhin, L Ooi,[...]. Nature 2002
10
Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives.
Hiroyuki Watanabe, John B Davis, Darren Smart, Jeff C Jerman, Graham D Smith, Phil Hayes, Joris Vriens, William Cairns, Ullrich Wissenbach, Jean Prenen,[...]. J Biol Chem 2002
Hiroyuki Watanabe, John B Davis, Darren Smart, Jeff C Jerman, Graham D Smith, Phil Hayes, Joris Vriens, William Cairns, Ullrich Wissenbach, Jean Prenen,[...]. J Biol Chem 2002
10
Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels.
Hiroyuki Watanabe, Joris Vriens, Jean Prenen, Guy Droogmans, Thomas Voets, Bernd Nilius. Nature 2003
Hiroyuki Watanabe, Joris Vriens, Jean Prenen, Guy Droogmans, Thomas Voets, Bernd Nilius. Nature 2003
10
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.