A citation-based method for searching scientific literature

J F Gusella, N S Wexler, P M Conneally, S L Naylor, M A Anderson, R E Tanzi, P C Watkins, K Ottina, M R Wallace, A Y Sakaguchi. Nature 1983
Times Cited: 1718







List of co-cited articles
910 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity



The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease.
S E Andrew, Y P Goldberg, B Kremer, H Telenius, J Theilmann, S Adam, E Starr, F Squitieri, B Lin, M A Kalchman. Nat Genet 1993
778
19


Huntington's disease: from molecular pathogenesis to clinical treatment.
Christopher A Ross, Sarah J Tabrizi. Lancet Neurol 2011
851
16

Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset.
Nancy S Wexler, Judith Lorimer, Julie Porter, Fidela Gomez, Carol Moskowitz, Edith Shackell, Karen Marder, Graciela Penchaszadeh, Simone A Roberts, Javier Gayán,[...]. Proc Natl Acad Sci U S A 2004
468
14

Huntington disease: natural history, biomarkers and prospects for therapeutics.
Christopher A Ross, Elizabeth H Aylward, Edward J Wild, Douglas R Langbehn, Jeffrey D Long, John H Warner, Rachael I Scahill, Blair R Leavitt, Julie C Stout, Jane S Paulsen,[...]. Nat Rev Neurol 2014
493
12

Trinucleotide repeat length instability and age of onset in Huntington's disease.
M Duyao, C Ambrose, R Myers, A Novelletto, F Persichetti, M Frontali, S Folstein, C Ross, M Franz, M Abbott. Nat Genet 1993
797
11

Neuropathological classification of Huntington's disease.
J P Vonsattel, R H Myers, T J Stevens, R J Ferrante, E D Bird, E P Richardson. J Neuropathol Exp Neurol 1985
11

Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease.
R G Snell, J C MacMillan, J P Cheadle, I Fenton, L P Lazarou, P Davies, M E MacDonald, J F Gusella, P S Harper, D J Shaw. Nat Genet 1993
577
10

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
10

CAG size-specific risk estimates for intermediate allele repeat instability in Huntington disease.
Alicia Semaka, Chris Kay, Crystal Doty, Jennifer A Collins, Emilia K Bijlsma, Fiona Richards, Y Paul Goldberg, Michael R Hayden. J Med Genet 2013
42
21

Initial sequencing and analysis of the human genome.
E S Lander, L M Linton, B Birren, C Nusbaum, M C Zody, J Baldwin, K Devon, K Dewar, M Doyle, W FitzHugh,[...]. Nature 2001
9

Huntington's disease: a clinical review.
Raymund A C Roos. Orphanet J Rare Dis 2010
384
9

The incidence and prevalence of Huntington's disease: a systematic review and meta-analysis.
Tamara Pringsheim, Katie Wiltshire, Lundy Day, Jonathan Dykeman, Thomas Steeves, Nathalie Jette. Mov Disord 2012
254
9

Huntington disease.
Gillian P Bates, Ray Dorsey, James F Gusella, Michael R Hayden, Chris Kay, Blair R Leavitt, Martha Nance, Christopher A Ross, Rachael I Scahill, Ronald Wetzel,[...]. Nat Rev Dis Primers 2015
503
9

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
9

Detection of Huntington's disease decades before diagnosis: the Predict-HD study.
J S Paulsen, D R Langbehn, J C Stout, E Aylward, C A Ross, M Nance, M Guttman, S Johnson, M MacDonald, L J Beglinger,[...]. J Neurol Neurosurg Psychiatry 2008
514
8

CAG expansion in the Huntington disease gene is associated with a specific and targetable predisposing haplogroup.
Simon C Warby, Alexandre Montpetit, Anna R Hayden, Jeffrey B Carroll, Stefanie L Butland, Henk Visscher, Jennifer A Collins, Alicia Semaka, Thomas J Hudson, Michael R Hayden. Am J Hum Genet 2009
131
8

Genetic modifiers of Huntington's disease.
James F Gusella, Marcy E MacDonald, Jong-Min Lee. Mov Disord 2014
63
12

Phenotypic characterization of individuals with 30-40 CAG repeats in the Huntington disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals with 36-39 repeats.
D C Rubinsztein, J Leggo, R Coles, E Almqvist, V Biancalana, J J Cassiman, K Chotai, M Connarty, D Crauford, A Curtis,[...]. Am J Hum Genet 1996
339
8

Predictors of phenotypic progression and disease onset in premanifest and early-stage Huntington's disease in the TRACK-HD study: analysis of 36-month observational data.
Sarah J Tabrizi, Rachael I Scahill, Gail Owen, Alexandra Durr, Blair R Leavitt, Raymund A Roos, Beth Borowsky, Bernhard Landwehrmeyer, Chris Frost, Hans Johnson,[...]. Lancet Neurol 2013
464
8

A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease.
Maria Björkqvist, Edward J Wild, Jenny Thiele, Aurelio Silvestroni, Ralph Andre, Nayana Lahiri, Elsa Raibon, Richard V Lee, Caroline L Benn, Denis Soulet,[...]. J Exp Med 2008
358
8

The role of tau in the pathological process and clinical expression of Huntington's disease.
Romina Vuono, Sophie Winder-Rhodes, Rohan de Silva, Giulia Cisbani, Janelle Drouin-Ouellet, Maria G Spillantini, Francesca Cicchetti, Roger A Barker. Brain 2015
67
11



CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion.
J-M Lee, E M Ramos, J-H Lee, T Gillis, J S Mysore, M R Hayden, S C Warby, P Morrison, M Nance, C A Ross,[...]. Neurology 2012
182
7



Huntington disease.
J P Vonsattel, M DiFiglia. J Neuropathol Exp Neurol 1998
7

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease.
M H Polymeropoulos, C Lavedan, E Leroy, S E Ide, A Dehejia, A Dutra, B Pike, H Root, J Rubenstein, R Boyer,[...]. Science 1997
7

Prevalence of adult Huntington's disease in the UK based on diagnoses recorded in general practice records.
Stephen J W Evans, Ian Douglas, Michael D Rawlins, Nancy S Wexler, Sarah J Tabrizi, Liam Smeeth. J Neurol Neurosurg Psychiatry 2013
96
7

Sustained therapeutic reversal of Huntington's disease by transient repression of huntingtin synthesis.
Holly B Kordasiewicz, Lisa M Stanek, Edward V Wancewicz, Curt Mazur, Melissa M McAlonis, Kimberly A Pytel, Jonathan W Artates, Andreas Weiss, Seng H Cheng, Lamya S Shihabuddin,[...]. Neuron 2012
433
7

Huntington's disease.
Francis O Walker. Lancet 2007
7

Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS.
Mariely DeJesus-Hernandez, Ian R Mackenzie, Bradley F Boeve, Adam L Boxer, Matt Baker, Nicola J Rutherford, Alexandra M Nicholson, NiCole A Finch, Heather Flynn, Jennifer Adamson,[...]. Neuron 2011
7

C9orf72 expansions are the most common genetic cause of Huntington disease phenocopies.
Davina J Hensman Moss, Mark Poulter, Jon Beck, Jason Hehir, James M Polke, Tracy Campbell, Garry Adamson, Ese Mudanohwo, Peter McColgan, Andrea Haworth,[...]. Neurology 2014
124
7

Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors.
Andrea Crotti, Christopher Benner, Bilal E Kerman, David Gosselin, Clotilde Lagier-Tourenne, Chiara Zuccato, Elena Cattaneo, Fred H Gage, Don W Cleveland, Christopher K Glass. Nat Neurosci 2014
166
7

Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington's disease patients.
Edward J Wild, Roberto Boggio, Douglas Langbehn, Nicola Robertson, Salman Haider, James R C Miller, Henrik Zetterberg, Blair R Leavitt, Rainer Kuhn, Sarah J Tabrizi,[...]. J Clin Invest 2015
112
7

The Biology of Huntingtin.
Frédéric Saudou, Sandrine Humbert. Neuron 2016
320
7

The likelihood of being affected with Huntington disease by a particular age, for a specific CAG size.
R R Brinkman, M M Mezei, J Theilmann, E Almqvist, M R Hayden. Am J Hum Genet 1997
252
6

High frequency of intermediate alleles on Huntington disease-associated haplotypes in British Columbia's general population.
Alicia Semaka, Chris Kay, Crystal N Doty, Jennifer A Collins, Natalie Tam, Michael R Hayden. Am J Med Genet B Neuropsychiatr Genet 2013
29
20

Finding the missing heritability of complex diseases.
Teri A Manolio, Francis S Collins, Nancy J Cox, David B Goldstein, Lucia A Hindorff, David J Hunter, Mark I McCarthy, Erin M Ramos, Lon R Cardon, Aravinda Chakravarti,[...]. Nature 2009
6

A global reference for human genetic variation.
Adam Auton, Lisa D Brooks, Richard M Durbin, Erik P Garrison, Hyun Min Kang, Jan O Korbel, Jonathan L Marchini, Shane McCarthy, Gil A McVean, Gonçalo R Abecasis. Nature 2015
6

Common SNP-based haplotype analysis of the 4p16.3 Huntington disease gene region.
Jong-Min Lee, Tammy Gillis, Jayalakshmi Srinidhi Mysore, Eliana Marisa Ramos, Richard H Myers, Michael R Hayden, Patrick J Morrison, Martha Nance, Christopher A Ross, Russell L Margolis,[...]. Am J Hum Genet 2012
41
14

Analysis of protein-coding genetic variation in 60,706 humans.
Monkol Lek, Konrad J Karczewski, Eric V Minikel, Kaitlin E Samocha, Eric Banks, Timothy Fennell, Anne H O'Donnell-Luria, James S Ware, Andrew J Hill, Beryl B Cummings,[...]. Nature 2016
6

Diagnostic criteria for Huntington's disease based on natural history.
Ralf Reilmann, Blair R Leavitt, Christopher A Ross. Mov Disord 2014
94
6

Mutant huntingtin is present in neuronal grafts in Huntington disease patients.
Francesca Cicchetti, Steve Lacroix, Giulia Cisbani, Nicolas Vallières, Martine Saint-Pierre, Isabelle St-Amour, Ranna Tolouei, Jeremy N Skepper, Robert A Hauser, Diego Mantovani,[...]. Ann Neurol 2014
110
6

Intergenerational and striatal CAG repeat instability in Huntington's disease knock-in mice involve different DNA repair genes.
Ella Dragileva, Audrey Hendricks, Allison Teed, Tammy Gillis, Edith T Lopez, Errol C Friedberg, Raju Kucherlapati, Winfried Edelmann, Kathryn L Lunetta, Marcy E MacDonald,[...]. Neurobiol Dis 2009
132
6

Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion.
J K White, W Auerbach, M P Duyao, J P Vonsattel, J F Gusella, A L Joyner, M E MacDonald. Nat Genet 1997
364
6

Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy.
A R La Spada, E M Wilson, D B Lubahn, A E Harding, K H Fischbeck. Nature 1991
6

RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model.
Scott Q Harper, Patrick D Staber, Xiaohua He, Steven L Eliason, Inês H Martins, Qinwen Mao, Linda Yang, Robert M Kotin, Henry L Paulson, Beverly L Davidson. Proc Natl Acad Sci U S A 2005
487
6


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.