A citation-based method for searching scientific literature

L Pegoraro, A Palumbo, J Erikson, M Falda, B Giovanazzo, B S Emanuel, G Rovera, P C Nowell, C M Croce. Proc Natl Acad Sci U S A 1984
Times Cited: 233

List of co-cited articles
843 articles co-cited >1

Times Cited
  Times     Co-cited

An inhibitor of Bcl-2 family proteins induces regression of solid tumours.
Tilman Oltersdorf, Steven W Elmore, Alexander R Shoemaker, Robert C Armstrong, David J Augeri, Barbara A Belli, Milan Bruncko, Thomas L Deckwerth, Jurgen Dinges, Philip J Hajduk,[...]. Nature 2005

The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.
Mark F van Delft, Andrew H Wei, Kylie D Mason, Cassandra J Vandenberg, Lin Chen, Peter E Czabotar, Simon N Willis, Clare L Scott, Catherine L Day, Suzanne Cory,[...]. Cancer Cell 2006

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death.
D Hockenbery, G Nuñez, C Milliman, R D Schreiber, S J Korsmeyer. Nature 1990

ABT-263: a potent and orally bioavailable Bcl-2 family inhibitor.
Christin Tse, Alexander R Shoemaker, Jessica Adickes, Mark G Anderson, Jun Chen, Sha Jin, Eric F Johnson, Kennan C Marsh, Michael J Mitten, Paul Nimmer,[...]. Cancer Res 2008

Clinical, morphologic, and cytogenetic characteristics of patients with lymphoid malignancies characterized by both t(14;18)(q32;q21) and t(8;14)(q24;q32) or t(8;22)(q24;q11).
M Thangavelu, O Olopade, E Beckman, J W Vardiman, R A Larson, T W McKeithan, M M Le Beau, J D Rowley. Genes Chromosomes Cancer 1990

bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation.
T J McDonnell, N Deane, F M Platt, G Nunez, U Jaeger, J P McKearn, S J Korsmeyer. Cell 1989

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics.
Anthony Letai, Michael C Bassik, Loren D Walensky, Mia D Sorcinelli, Solly Weiler, Stanley J Korsmeyer. Cancer Cell 2002

ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets.
Andrew J Souers, Joel D Leverson, Erwin R Boghaert, Scott L Ackler, Nathaniel D Catron, Jun Chen, Brian D Dayton, Hong Ding, Sari H Enschede, Wayne J Fairbrother,[...]. Nat Med 2013

The BCL-2 protein family: opposing activities that mediate cell death.
Richard J Youle, Andreas Strasser. Nat Rev Mol Cell Biol 2008

Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members.
Michael Certo, Victoria Del Gaizo Moore, Mari Nishino, Guo Wei, Stanley Korsmeyer, Scott A Armstrong, Anthony Letai. Cancer Cell 2006

C-MYC translocations in de novo B-cell lineage acute leukemias with t(14;18)(cell lines Karpas 231 and 353).
E Nacheva, M J Dyer, P Fischer, G Stranks, J M Heward, R E Marcus, C Grace, A Karpas. Blood 1993

Acute lymphoblastic leukemia with the (8;14)(q24;q32) translocation and FAB L3 morphology associated with a B-precursor immunophenotype: the Pediatric Oncology Group experience.
F Navid, A D Mosijczuk, D R Head, M J Borowitz, A J Carroll, J M Brandt, M P Link, M K Rozans, G A Thomas, M R Schwenn,[...]. Leukemia 1999

Simultaneous occurrence of t(14;18) and t(8;22) common acute lymphoblastic leukemia.
C Marosi, P Bettelheim, A Chott, U Köller, G Kreiner, G Steger, U Jäger, H Pirc-Danoewinata, K Lechner. Ann Hematol 1992

The Bcl2 family: regulators of the cellular life-or-death switch.
Suzanne Cory, Jerry M Adams. Nat Rev Cancer 2002

Involvement of the bcl-2 gene in human follicular lymphoma.
Y Tsujimoto, J Cossman, E Jaffe, C M Croce. Science 1985

Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia.
Marina Konopleva, Rooha Contractor, Twee Tsao, Ismael Samudio, Peter P Ruvolo, Shinichi Kitada, Xingming Deng, Dayong Zhai, Yue-Xi Shi, Thomas Sneed,[...]. Cancer Cell 2006

Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak.
Simon N Willis, Jamie I Fletcher, Thomas Kaufmann, Mark F van Delft, Lin Chen, Peter E Czabotar, Helen Ierino, Erinna F Lee, W Douglas Fairlie, Philippe Bouillet,[...]. Science 2007

Navitoclax, a targeted high-affinity inhibitor of BCL-2, in lymphoid malignancies: a phase 1 dose-escalation study of safety, pharmacokinetics, pharmacodynamics, and antitumour activity.
Wyndham H Wilson, Owen A O'Connor, Myron S Czuczman, Ann S LaCasce, John F Gerecitano, John P Leonard, Anil Tulpule, Kieron Dunleavy, Hao Xiong, Yi-Lin Chiu,[...]. Lancet Oncol 2010

Phase I study of Navitoclax (ABT-263), a novel Bcl-2 family inhibitor, in patients with small-cell lung cancer and other solid tumors.
Leena Gandhi, D Ross Camidge, Moacyr Ribeiro de Oliveira, Philip Bonomi, David Gandara, Divis Khaira, Christine L Hann, Evelyn M McKeegan, Elizabeth Litvinovich, Philip M Hemken,[...]. J Clin Oncol 2011

De novo acute B-cell leukemia with translocation t(14;18): an entity with a poor prognosis.
M H Kramer, S Raghoebier, G C Beverstock, D de Jong, P M Kluin, J C Kluin-Nelemans. Leukemia 1991

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death.
L H Boise, M González-García, C E Postema, L Ding, T Lindsten, L A Turka, X Mao, G Nuñez, C B Thompson. Cell 1993

Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around JH on chromosome 14 and near a transcriptional unit on 18.
A Bakhshi, J P Jensen, P Goldman, J J Wright, O W McBride, A L Epstein, S J Korsmeyer. Cell 1985

BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly.
Tomomi Kuwana, Lisa Bouchier-Hayes, Jerry E Chipuk, Christine Bonzon, Barbara A Sullivan, Douglas R Green, Donald D Newmeyer. Mol Cell 2005

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function.
Lin Chen, Simon N Willis, Andrew Wei, Brian J Smith, Jamie I Fletcher, Mark G Hinds, Peter M Colman, Catherine L Day, Jerry M Adams, David C S Huang. Mol Cell 2005

Substantial susceptibility of chronic lymphocytic leukemia to BCL2 inhibition: results of a phase I study of navitoclax in patients with relapsed or refractory disease.
Andrew W Roberts, John F Seymour, Jennifer R Brown, William G Wierda, Thomas J Kipps, Seong Lin Khaw, Dennis A Carney, Simon Z He, David C S Huang, Hao Xiong,[...]. J Clin Oncol 2012

De novo acute B cell leukemia/lymphoma with t(14;18).
A Stamatoullas, G Buchonnet, S Lepretre, P Lenain, B Lenormand, C Duval, M P Callat, P Gaulard, C Bastard, H Tilly. Leukemia 2000

A new B-cell line showing a complex translocation (8;14;18) and BCL2 rearrangement.
R B van Ooteghem, E M Smit, A Beishuizen, A C Lambrechts, M vd Blij-Philipsen, T J Smilde, A Hagemeijer. Cancer Genet Cytogenet 1994

The hallmarks of cancer.
D Hanahan, R A Weinberg. Cell 2000

Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane.
Tomomi Kuwana, Mason R Mackey, Guy Perkins, Mark H Ellisman, Martin Latterich, Roger Schneiter, Douglas R Green, Donald D Newmeyer. Cell 2002

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death.
S W Muchmore, M Sattler, H Liang, R P Meadows, J E Harlan, H S Yoon, D Nettesheim, B S Chang, C B Thompson, S L Wong,[...]. Nature 1996

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice.
N Motoyama, F Wang, K A Roth, H Sawa, K Nakayama, K Nakayama, I Negishi, S Senju, Q Zhang, S Fujii. Science 1995

miR-15 and miR-16 induce apoptosis by targeting BCL2.
Amelia Cimmino, George Adrian Calin, Muller Fabbri, Marilena V Iorio, Manuela Ferracin, Masayoshi Shimizu, Sylwia E Wojcik, Rami I Aqeilan, Simona Zupo, Mariella Dono,[...]. Proc Natl Acad Sci U S A 2005

Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis.
Mai Nguyen, Richard C Marcellus, Anne Roulston, Mark Watson, Lucile Serfass, S R Murthy Madiraju, Daniel Goulet, Jean Viallet, Laurent Bélec, Xavier Billot,[...]. Proc Natl Acad Sci U S A 2007

Lymphomas with concurrent BCL2 and MYC translocations: the critical factors associated with survival.
Nathalie A Johnson, Kerry J Savage, Olga Ludkovski, Susana Ben-Neriah, Ryan Woods, Christian Steidl, Martin J S Dyer, Reiner Siebert, John Kuruvilla, Richard Klasa,[...]. Blood 2009

Programmed anuclear cell death delimits platelet life span.
Kylie D Mason, Marina R Carpinelli, Jamie I Fletcher, Janelle E Collinge, Adrienne A Hilton, Sarah Ellis, Priscilla N Kelly, Paul G Ekert, Donald Metcalf, Andrew W Roberts,[...]. Cell 2007

Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy.
Triona Ni Chonghaile, Kristopher A Sarosiek, Thanh-Trang Vo, Jeremy A Ryan, Anupama Tammareddi, Victoria Del Gaizo Moore, Jing Deng, Kenneth C Anderson, Paul Richardson, Yu-Tzu Tai,[...]. Science 2011

Activation of the c-myc oncogene in a precursor-B-cell blast crisis of follicular lymphoma, presenting as composite lymphoma.
D De Jong, B M Voetdijk, G C Beverstock, G J van Ommen, R Willemze, P M Kluin. N Engl J Med 1988

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis.
M Sattler, H Liang, D Nettesheim, R P Meadows, J E Harlan, M Eberstadt, H S Yoon, S B Shuker, B S Chang, A J Minn,[...]. Science 1997

The t(14;18) defines a unique subset of diffuse large B-cell lymphoma with a germinal center B-cell gene expression profile.
James Z Huang, Warren G Sanger, Timothy C Greiner, Louis M Staudt, Dennis D Weisenburger, Diane L Pickering, James C Lynch, James O Armitage, Roger A Warnke, Ash A Alizadeh,[...]. Blood 2002

Translocations t(14;18) and t(8;14) with rearranged bcl-2 and c-myc in a case presenting as B-ALL (L3).
V Brito-Babapulle, A Crawford, T Khokhar, M Laffan, E Matutes, S Fairhead, D Catovsky. Leukemia 1991

MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2.
K M Kozopas, T Yang, H L Buchan, P Zhou, R W Craig. Proc Natl Acad Sci U S A 1993

Lymphoid neoplasms associated with concurrent t(14;18) and 8q24/c-MYC translocation generally have a poor prognosis.
Anuradha Kanungo, L Jeffrey Medeiros, Lynne V Abruzzo, Pei Lin. Mod Pathol 2006

Different forms of cell death induced by putative BCL2 inhibitors.
M Vogler, K Weber, D Dinsdale, I Schmitz, K Schulze-Osthoff, M J S Dyer, G M Cohen. Cell Death Differ 2009

Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.