A citation-based method for searching scientific literature

C Nüsslein-Volhard, E Wieschaus. Nature 1980
Times Cited: 2871







List of co-cited articles
788 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


The mechanisms of Hedgehog signalling and its roles in development and disease.
James Briscoe, Pascal P Thérond. Nat Rev Mol Cell Biol 2013
945
11


The role of the Hedgehog signaling pathway in cancer: A comprehensive review.
Ana Marija Skoda, Dora Simovic, Valentina Karin, Vedran Kardum, Semir Vranic, Ljiljana Serman. Bosn J Basic Med Sci 2018
160
9

Hedgehog: functions and mechanisms.
Markku Varjosalo, Jussi Taipale. Genes Dev 2008
819
9

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity.
Y Echelard, D J Epstein, B St-Jacques, L Shen, J Mohler, J A McMahon, A P McMahon. Cell 1993
8


Patched1 regulates hedgehog signaling at the primary cilium.
Rajat Rohatgi, Ljiljana Milenkovic, Matthew P Scott. Science 2007
942
8


Efficacy and safety of vismodegib in advanced basal-cell carcinoma.
Aleksandar Sekulic, Michael R Migden, Anthony E Oro, Luc Dirix, Karl D Lewis, John D Hainsworth, James A Solomon, Simon Yoo, Sarah T Arron, Philip A Friedlander,[...]. N Engl J Med 2012
816
7

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function.
C Chiang, Y Litingtung, E Lee, K E Young, J L Corden, H Westphal, P A Beachy. Nature 1996
7

Dispatched and scube mediate the efficient secretion of the cholesterol-modified hedgehog ligand.
Hanna Tukachinsky, Ryan P Kuzmickas, Cindy Y Jao, Jing Liu, Adrian Salic. Cell Rep 2012
124
7


Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways.
Barbara Stecca, Christophe Mas, Virginie Clement, Marie Zbinden, Rafael Correa, Vincent Piguet, Friedrich Beermann, Ariel Ruiz i Altaba. Proc Natl Acad Sci U S A 2007
382
6

Wnt/beta-catenin signaling: components, mechanisms, and diseases.
Bryan T MacDonald, Keiko Tamai, Xi He. Dev Cell 2009
6

A pair-rule gene circuit defines segments sequentially in the short-germ insect Tribolium castaneum.
Chong Pyo Choe, Sherry C Miller, Susan J Brown. Proc Natl Acad Sci U S A 2006
132
6

Desert Hedgehog/Patched 1 signaling specifies fetal Leydig cell fate in testis organogenesis.
Humphrey Hung-Chang Yao, Wendy Whoriskey, Blanche Capel. Genes Dev 2002
320
6


Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3.
P Dai, H Akimaru, Y Tanaka, T Maekawa, M Nakafuku, S Ishii. J Biol Chem 1999
419
6


Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling.
Pengxiang Huang, Daniel Nedelcu, Miyako Watanabe, Cindy Jao, Youngchang Kim, Jing Liu, Adrian Salic. Cell 2016
187
6

Structures of human Patched and its complex with native palmitoylated sonic hedgehog.
Xiaofeng Qi, Philip Schmiege, Elias Coutavas, Jiawei Wang, Xiaochun Li. Nature 2018
89
6

A highlight on Sonic hedgehog pathway.
Gabriela Basile Carballo, Jéssica Ribeiro Honorato, Giselle Pinto Farias de Lopes, Tania Cristina Leite de Sampaio E Spohr. Cell Commun Signal 2018
104
6

Vertebrate Smoothened functions at the primary cilium.
Kevin C Corbit, Pia Aanstad, Veena Singla, Andrew R Norman, Didier Y R Stainier, Jeremy F Reiter. Nature 2005
993
6

Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord.
H Roelink, A Augsburger, J Heemskerk, V Korzh, S Norlin, A Ruiz i Altaba, Y Tanabe, M Placzek, T Edlund, T M Jessell. Cell 1994
743
5

Activating Smoothened mutations in sporadic basal-cell carcinoma.
J Xie, M Murone, S M Luoh, A Ryan, Q Gu, C Zhang, J M Bonifas, C W Lam, M Hynes, A Goddard,[...]. Nature 1998
982
5

The Hedgehog response network: sensors, switches, and routers.
Lawrence Lum, Philip A Beachy. Science 2004
614
5

Roles for Hedgehog signaling in adult organ homeostasis and repair.
Ralitsa Petrova, Alexandra L Joyner. Development 2014
197
5


Targeting the Hedgehog pathway in cancer.
Sachin Gupta, Naoko Takebe, Patricia Lorusso. Ther Adv Med Oncol 2010
173
5

Gene regulatory logic for reading the Sonic Hedgehog signaling gradient in the vertebrate neural tube.
Nikolaos Balaskas, Ana Ribeiro, Jasmina Panovska, Eric Dessaud, Noriaki Sasai, Karen M Page, James Briscoe, Vanessa Ribes. Cell 2012
273
5


Developmental roles and clinical significance of hedgehog signaling.
Andrew P McMahon, Philip W Ingham, Clifford J Tabin. Curr Top Dev Biol 2003
657
5

The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins.
Eric W Humke, Karolin V Dorn, Ljiljana Milenkovic, Matthew P Scott, Rajat Rohatgi. Genes Dev 2010
303
5


Dynamic control of positional information in the early Drosophila embryo.
Johannes Jaeger, Svetlana Surkova, Maxim Blagov, Hilde Janssens, David Kosman, Konstantin N Kozlov, Manu, Ekaterina Myasnikova, Carlos E Vanario-Alonso, Maria Samsonova,[...]. Nature 2004
359
5

Sertoli cell signaling by Desert hedgehog regulates the male germline.
M J Bitgood, L Shen, A P McMahon. Curr Biol 1996
460
5

Structural basis for the recognition of Sonic Hedgehog by human Patched1.
Xin Gong, Hongwu Qian, Pingping Cao, Xin Zhao, Qiang Zhou, Jianlin Lei, Nieng Yan. Science 2018
99
5

Biochemical mechanisms of vertebrate hedgehog signaling.
Jennifer H Kong, Christian Siebold, Rajat Rohatgi. Development 2019
76
6

Gli protein activity is controlled by multisite phosphorylation in vertebrate Hedgehog signaling.
Pawel Niewiadomski, Jennifer H Kong, Robert Ahrends, Yan Ma, Eric W Humke, Sohini Khan, Mary N Teruel, Bennett G Novitch, Rajat Rohatgi. Cell Rep 2014
133
5



Gli Proteins: Regulation in Development and Cancer.
Paweł Niewiadomski, Sylwia M Niedziółka, Łukasz Markiewicz, Tomasz Uśpieński, Brygida Baran, Katarzyna Chojnowska. Cells 2019
43
11

Primary Cilia and Mammalian Hedgehog Signaling.
Fiona Bangs, Kathryn V Anderson. Cold Spring Harb Perspect Biol 2017
225
5

Hedgehog signalling in the mouse requires intraflagellar transport proteins.
Danwei Huangfu, Aimin Liu, Andrew S Rakeman, Noel S Murcia, Lee Niswander, Kathryn V Anderson. Nature 2003
957
5

Human homolog of patched, a candidate gene for the basal cell nevus syndrome.
R L Johnson, A L Rothman, J Xie, L V Goodrich, J W Bare, J M Bonifas, A G Quinn, R M Myers, D R Cox, E H Epstein,[...]. Science 1996
4


Products, genetic linkage and limb patterning activity of a murine hedgehog gene.
D T Chang, A López, D P von Kessler, C Chiang, B K Simandl, R Zhao, M F Seldin, J F Fallon, P A Beachy. Development 1994
243
4

A theory of biological pattern formation.
A Gierer, H Meinhardt. Kybernetik 1972
4

The Wnt signaling pathway in development and disease.
Catriona Y Logan, Roel Nusse. Annu Rev Cell Dev Biol 2004
4

Targeting the Hedgehog pathway in cancer.
Lee L Rubin, Frederic J de Sauvage. Nat Rev Drug Discov 2006
572
4


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.