T Takahashi, M Tanaka, C I Brannan, N A Jenkins, N G Copeland, T Suda, S Nagata. Cell 1994
Times Cited: 1470
Times Cited: 1470
Times Cited
Times Co-cited
Similarity
Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis.
R Watanabe-Fukunaga, C I Brannan, N G Copeland, N A Jenkins, S Nagata. Nature 1992
R Watanabe-Fukunaga, C I Brannan, N G Copeland, N A Jenkins, S Nagata. Nature 1992
42
Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome.
G H Fisher, F J Rosenberg, S E Straus, J K Dale, L A Middleton, A Y Lin, W Strober, M J Lenardo, J M Puck. Cell 1995
G H Fisher, F J Rosenberg, S E Straus, J K Dale, L A Middleton, A Y Lin, W Strober, M J Lenardo, J M Puck. Cell 1995
22
Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity.
F Rieux-Laucat, F Le Deist, C Hivroz, I A Roberts, K M Debatin, A Fischer, J P de Villartay. Science 1995
F Rieux-Laucat, F Le Deist, C Hivroz, I A Roberts, K M Debatin, A Fischer, J P de Villartay. Science 1995
21
Membrane-bound Fas ligand only is essential for Fas-induced apoptosis.
Lorraine A O' Reilly, Lin Tai, Lily Lee, Elizabeth A Kruse, Stephanie Grabow, W Douglas Fairlie, Nicole M Haynes, David M Tarlinton, Jian-Guo Zhang, Gabrielle T Belz,[...]. Nature 2009
Lorraine A O' Reilly, Lin Tai, Lily Lee, Elizabeth A Kruse, Stephanie Grabow, W Douglas Fairlie, Nicole M Haynes, David M Tarlinton, Jian-Guo Zhang, Gabrielle T Belz,[...]. Nature 2009
14
Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family.
T Suda, T Takahashi, P Golstein, S Nagata. Cell 1993
T Suda, T Takahashi, P Golstein, S Nagata. Cell 1993
13
Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation.
S T Ju, D J Panka, H Cui, R Ettinger, M el-Khatib, D H Sherr, B Z Stanger, A Marshak-Rothstein. Nature 1995
S T Ju, D J Panka, H Cui, R Ettinger, M el-Khatib, D H Sherr, B Z Stanger, A Marshak-Rothstein. Nature 1995
13
The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis.
N Itoh, S Yonehara, A Ishii, M Yonehara, S Mizushima, M Sameshima, A Hase, Y Seto, S Nagata. Cell 1991
N Itoh, S Yonehara, A Ishii, M Yonehara, S Mizushima, M Sameshima, A Hase, Y Seto, S Nagata. Cell 1991
12
Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease.
J Wu, J Wilson, J He, L Xiang, P H Schur, J D Mountz. J Clin Invest 1996
J Wu, J Wilson, J He, L Xiang, P H Schur, J D Mountz. J Clin Invest 1996
12
A novel lymphoproliferative/autoimmune syndrome resembling murine lpr/gld disease.
M C Sneller, S E Straus, E S Jaffe, J S Jaffe, T A Fleisher, M Stetler-Stevenson, W Strober. J Clin Invest 1992
M C Sneller, S E Straus, E S Jaffe, J S Jaffe, T A Fleisher, M Stetler-Stevenson, W Strober. J Clin Invest 1992
11
Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity.
P Schneider, N Holler, J L Bodmer, M Hahne, K Frei, A Fontana, J Tschopp. J Exp Med 1998
P Schneider, N Holler, J L Bodmer, M Hahne, K Frei, A Fontana, J Tschopp. J Exp Med 1998
11
The many roles of FAS receptor signaling in the immune system.
Andreas Strasser, Philipp J Jost, Shigekazu Nagata. Immunity 2009
Andreas Strasser, Philipp J Jost, Shigekazu Nagata. Immunity 2009
10
The mouse Fas-ligand gene is mutated in gld mice and is part of a TNF family gene cluster.
D H Lynch, M L Watson, M R Alderson, P R Baum, R E Miller, T Tough, M Gibson, T Davis-Smith, C A Smith, K Hunter. Immunity 1994
D H Lynch, M L Watson, M R Alderson, P R Baum, R E Miller, T Tough, M Gibson, T Davis-Smith, C A Smith, K Hunter. Immunity 1994
10
Elimination of antigen-presenting cells and autoreactive T cells by Fas contributes to prevention of autoimmunity.
Peter B Stranges, Jessica Watson, Cristie J Cooper, Caroline-Morgane Choisy-Rossi, Austin C Stonebraker, Ryan A Beighton, Heather Hartig, John P Sundberg, Stein Servick, Gunnar Kaufmann,[...]. Immunity 2007
Peter B Stranges, Jessica Watson, Cristie J Cooper, Caroline-Morgane Choisy-Rossi, Austin C Stonebraker, Ryan A Beighton, Heather Hartig, John P Sundberg, Stein Servick, Gunnar Kaufmann,[...]. Immunity 2007
9
Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas.
T Brunner, R J Mogil, D LaFace, N J Yoo, A Mahboubi, F Echeverri, S J Martin, W R Force, D H Lynch, C F Ware. Nature 1995
T Brunner, R J Mogil, D LaFace, N J Yoo, A Mahboubi, F Echeverri, S J Martin, W R Force, D H Lynch, C F Ware. Nature 1995
9
The naturally processed CD95L elicits a c-yes/calcium/PI3K-driven cell migration pathway.
Sébastien Tauzin, Benjamin Chaigne-Delalande, Eric Selva, Nadine Khadra, Sophie Daburon, Cécile Contin-Bordes, Patrick Blanco, Jacques Le Seyec, Thomas Ducret, Laurent Counillon,[...]. PLoS Biol 2011
Sébastien Tauzin, Benjamin Chaigne-Delalande, Eric Selva, Nadine Khadra, Sophie Daburon, Cécile Contin-Bordes, Patrick Blanco, Jacques Le Seyec, Thomas Ducret, Laurent Counillon,[...]. PLoS Biol 2011
12
Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor.
F C Kischkel, S Hellbardt, I Behrmann, M Germer, M Pawlita, P H Krammer, M E Peter. EMBO J 1995
F C Kischkel, S Hellbardt, I Behrmann, M Germer, M Pawlita, P H Krammer, M E Peter. EMBO J 1995
9
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation.
Young Sik Cho, Sreerupa Challa, David Moquin, Ryan Genga, Tathagat Dutta Ray, Melissa Guildford, Francis Ka-Ming Chan. Cell 2009
Young Sik Cho, Sreerupa Challa, David Moquin, Ryan Genga, Tathagat Dutta Ray, Melissa Guildford, Francis Ka-Ming Chan. Cell 2009
9
A new mutation, gld, that produces lymphoproliferation and autoimmunity in C3H/HeJ mice.
J B Roths, E D Murphy, E M Eicher. J Exp Med 1984
J B Roths, E D Murphy, E M Eicher. J Exp Med 1984
9
Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease.
P L Cohen, R A Eisenberg. Annu Rev Immunol 1991
P L Cohen, R A Eisenberg. Annu Rev Immunol 1991
9
Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase.
Liming Sun, Huayi Wang, Zhigao Wang, Sudan He, She Chen, Daohong Liao, Lai Wang, Jiacong Yan, Weilong Liu, Xiaoguang Lei,[...]. Cell 2012
Liming Sun, Huayi Wang, Zhigao Wang, Sudan He, She Chen, Daohong Liao, Lai Wang, Jiacong Yan, Weilong Liu, Xiaoguang Lei,[...]. Cell 2012
9
Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity.
Peter D Hughes, Gabrielle T Belz, Karen A Fortner, Ralph C Budd, Andreas Strasser, Philippe Bouillet. Immunity 2008
Peter D Hughes, Gabrielle T Belz, Karen A Fortner, Ralph C Budd, Andreas Strasser, Philippe Bouillet. Immunity 2008
8
Yes and PI3K bind CD95 to signal invasion of glioblastoma.
Susanne Kleber, Ignacio Sancho-Martinez, Benedict Wiestler, Alexandra Beisel, Christian Gieffers, Oliver Hill, Meinolf Thiemann, Wolf Mueller, Jaromir Sykora, Andreas Kuhn,[...]. Cancer Cell 2008
Susanne Kleber, Ignacio Sancho-Martinez, Benedict Wiestler, Alexandra Beisel, Christian Gieffers, Oliver Hill, Meinolf Thiemann, Wolf Mueller, Jaromir Sykora, Andreas Kuhn,[...]. Cancer Cell 2008
8
Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis.
Andrew Oberst, Christopher P Dillon, Ricardo Weinlich, Laura L McCormick, Patrick Fitzgerald, Cristina Pop, Razq Hakem, Guy S Salvesen, Douglas R Green. Nature 2011
Andrew Oberst, Christopher P Dillon, Ricardo Weinlich, Laura L McCormick, Patrick Fitzgerald, Cristina Pop, Razq Hakem, Guy S Salvesen, Douglas R Green. Nature 2011
8
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury.
Alexei Degterev, Zhihong Huang, Michael Boyce, Yaqiao Li, Prakash Jagtap, Noboru Mizushima, Gregory D Cuny, Timothy J Mitchison, Michael A Moskowitz, Junying Yuan. Nat Chem Biol 2005
Alexei Degterev, Zhihong Huang, Michael Boyce, Yaqiao Li, Prakash Jagtap, Noboru Mizushima, Gregory D Cuny, Timothy J Mitchison, Michael A Moskowitz, Junying Yuan. Nat Chem Biol 2005
8
Identification of RIP1 kinase as a specific cellular target of necrostatins.
Alexei Degterev, Junichi Hitomi, Megan Germscheid, Irene L Ch'en, Olga Korkina, Xin Teng, Derek Abbott, Gregory D Cuny, Chengye Yuan, Gerhard Wagner,[...]. Nat Chem Biol 2008
Alexei Degterev, Junichi Hitomi, Megan Germscheid, Irene L Ch'en, Olga Korkina, Xin Teng, Derek Abbott, Gregory D Cuny, Chengye Yuan, Gerhard Wagner,[...]. Nat Chem Biol 2008
8
Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains.
B S Andrews, R A Eisenberg, A N Theofilopoulos, S Izui, C B Wilson, P J McConahey, E D Murphy, J B Roths, F J Dixon. J Exp Med 1978
B S Andrews, R A Eisenberg, A N Theofilopoulos, S Izui, C B Wilson, P J McConahey, E D Murphy, J B Roths, F J Dixon. J Exp Med 1978
8
Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)
J Dhein, H Walczak, C Bäumler, K M Debatin, P H Krammer. Nature 1995
J Dhein, H Walczak, C Bäumler, K M Debatin, P H Krammer. Nature 1995
7
Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain.
Shanshan Feng, Yonghui Yang, Yide Mei, Li Ma, De-e Zhu, Naseruddin Hoti, Mark Castanares, Mian Wu. Cell Signal 2007
Shanshan Feng, Yonghui Yang, Yide Mei, Li Ma, De-e Zhu, Naseruddin Hoti, Mark Castanares, Mian Wu. Cell Signal 2007
7
Identification of novel matrix metalloproteinase-7 (matrilysin) cleavage sites in murine and human Fas ligand.
Tracy Vargo-Gogola, Howard C Crawford, Barbara Fingleton, Lynn M Matrisian. Arch Biochem Biophys 2002
Tracy Vargo-Gogola, Howard C Crawford, Barbara Fingleton, Lynn M Matrisian. Arch Biochem Biophys 2002
7
RIP3 mediates the embryonic lethality of caspase-8-deficient mice.
William J Kaiser, Jason W Upton, Alyssa B Long, Devon Livingston-Rosanoff, Lisa P Daley-Bauer, Razqallah Hakem, Tamara Caspary, Edward S Mocarski. Nature 2011
William J Kaiser, Jason W Upton, Alyssa B Long, Devon Livingston-Rosanoff, Lisa P Daley-Bauer, Razqallah Hakem, Tamara Caspary, Edward S Mocarski. Nature 2011
7
Fas ligand-induced apoptosis as a mechanism of immune privilege.
T S Griffith, T Brunner, S M Fletcher, D R Green, T A Ferguson. Science 1995
T S Griffith, T Brunner, S M Fletcher, D R Green, T A Ferguson. Science 1995
7
Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule.
N Holler, R Zaru, O Micheau, M Thome, A Attinger, S Valitutti, J L Bodmer, P Schneider, B Seed, J Tschopp. Nat Immunol 2000
N Holler, R Zaru, O Micheau, M Thome, A Attinger, S Valitutti, J L Bodmer, P Schneider, B Seed, J Tschopp. Nat Immunol 2000
7
The development of lymphomas in families with autoimmune lymphoproliferative syndrome with germline Fas mutations and defective lymphocyte apoptosis.
S E Straus, E S Jaffe, J M Puck, J K Dale, K B Elkon, A Rösen-Wolff, A M Peters, M C Sneller, C W Hallahan, J Wang,[...]. Blood 2001
S E Straus, E S Jaffe, J M Puck, J K Dale, K B Elkon, A Rösen-Wolff, A M Peters, M C Sneller, C W Hallahan, J Wang,[...]. Blood 2001
7
Membrane Fas ligand kills human peripheral blood T lymphocytes, and soluble Fas ligand blocks the killing.
T Suda, H Hashimoto, M Tanaka, T Ochi, S Nagata. J Exp Med 1997
T Suda, H Hashimoto, M Tanaka, T Ochi, S Nagata. J Exp Med 1997
7
FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis.
A M Chinnaiyan, K O'Rourke, M Tewari, V M Dixit. Cell 1995
A M Chinnaiyan, K O'Rourke, M Tewari, V M Dixit. Cell 1995
7
Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.
E E Varfolomeev, M Schuchmann, V Luria, N Chiannilkulchai, J S Beckmann, I L Mett, D Rebrikov, V M Brodianski, O C Kemper, O Kollet,[...]. Immunity 1998
E E Varfolomeev, M Schuchmann, V Luria, N Chiannilkulchai, J S Beckmann, I L Mett, D Rebrikov, V M Brodianski, O C Kemper, O Kollet,[...]. Immunity 1998
7
Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity.
P Bouillet, D Metcalf, D C Huang, D M Tarlinton, T W Kay, F Köntgen, J M Adams, A Strasser. Science 1999
P Bouillet, D Metcalf, D C Huang, D M Tarlinton, T W Kay, F Köntgen, J M Adams, A Strasser. Science 1999
7
CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+ T cells.
J C Rathmell, M P Cooke, W Y Ho, J Grein, S E Townsend, M M Davis, C C Goodnow. Nature 1995
J C Rathmell, M P Cooke, W Y Ho, J Grein, S E Townsend, M M Davis, C C Goodnow. Nature 1995
7
CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice.
Amanda Poissonnier, Doriane Sanséau, Matthieu Le Gallo, Marine Malleter, Nicolas Levoin, Roselyne Viel, Lucie Morere, Aubin Penna, Patrick Blanco, Alain Dupuy,[...]. Immunity 2016
Amanda Poissonnier, Doriane Sanséau, Matthieu Le Gallo, Marine Malleter, Nicolas Levoin, Roselyne Viel, Lucie Morere, Aubin Penna, Patrick Blanco, Alain Dupuy,[...]. Immunity 2016
14
Apoptosis regulators Bim and Fas function concurrently to control autoimmunity and CD8+ T cell contraction.
Ashley E Weant, Ryan D Michalek, Islam U Khan, Beth C Holbrook, Mark C Willingham, Jason M Grayson. Immunity 2008
Ashley E Weant, Ryan D Michalek, Islam U Khan, Beth C Holbrook, Mark C Willingham, Jason M Grayson. Immunity 2008
6
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex.
M Muzio, A M Chinnaiyan, F C Kischkel, K O'Rourke, A Shevchenko, J Ni, C Scaffidi, J D Bretz, M Zhang, R Gentz,[...]. Cell 1996
M Muzio, A M Chinnaiyan, F C Kischkel, K O'Rourke, A Shevchenko, J Ni, C Scaffidi, J D Bretz, M Zhang, R Gentz,[...]. Cell 1996
6
6
Fas (CD95) induces proinflammatory cytokine responses by human monocytes and monocyte-derived macrophages.
David R Park, Anni R Thomsen, Charles W Frevert, Uyenvy Pham, Shawn J Skerrett, Peter A Kiener, W Conrad Liles. J Immunol 2003
David R Park, Anni R Thomsen, Charles W Frevert, Uyenvy Pham, Shawn J Skerrett, Peter A Kiener, W Conrad Liles. J Immunol 2003
6
Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations.
R M Siegel, J K Frederiksen, D A Zacharias, F K Chan, M Johnson, D Lynch, R Y Tsien, M J Lenardo. Science 2000
R M Siegel, J K Frederiksen, D A Zacharias, F K Chan, M Johnson, D Lynch, R Y Tsien, M J Lenardo. Science 2000
6
Monoclonal antibody-mediated tumor regression by induction of apoptosis.
B C Trauth, C Klas, A M Peters, S Matzku, P Möller, W Falk, K M Debatin, P H Krammer. Science 1989
B C Trauth, C Klas, A M Peters, S Matzku, P Möller, W Falk, K M Debatin, P H Krammer. Science 1989
6
Inhibition of death receptor signals by cellular FLIP.
M Irmler, M Thome, M Hahne, P Schneider, K Hofmann, V Steiner, J L Bodmer, M Schröter, K Burns, C Mattmann,[...]. Nature 1997
M Irmler, M Thome, M Hahne, P Schneider, K Hofmann, V Steiner, J L Bodmer, M Schröter, K Burns, C Mattmann,[...]. Nature 1997
6
Linear ubiquitination prevents inflammation and regulates immune signalling.
Björn Gerlach, Stefanie M Cordier, Anna C Schmukle, Christoph H Emmerich, Eva Rieser, Tobias L Haas, Andrew I Webb, James A Rickard, Holly Anderton, Wendy W-L Wong,[...]. Nature 2011
Björn Gerlach, Stefanie M Cordier, Anna C Schmukle, Christoph H Emmerich, Eva Rieser, Tobias L Haas, Andrew I Webb, James A Rickard, Holly Anderton, Wendy W-L Wong,[...]. Nature 2011
6
CD95L cell surface cleavage triggers a prometastatic signaling pathway in triple-negative breast cancer.
Marine Malleter, Sébastien Tauzin, Alban Bessede, Rémy Castellano, Armelle Goubard, Florence Godey, Jean Levêque, Pascal Jézéquel, Loic Campion, Mario Campone,[...]. Cancer Res 2013
Marine Malleter, Sébastien Tauzin, Alban Bessede, Rémy Castellano, Armelle Goubard, Florence Godey, Jean Levêque, Pascal Jézéquel, Loic Campion, Mario Campone,[...]. Cancer Res 2013
10
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.