M Maes, S Scharpé, H Y Meltzer, E Bosmans, E Suy, J Calabrese, P Cosyns. Psychiatry Res 1993
Times Cited: 318
Times Cited: 318
Times Cited
Times Co-cited
Similarity
A meta-analysis of cytokines in major depression.
Yekta Dowlati, Nathan Herrmann, Walter Swardfager, Helena Liu, Lauren Sham, Elyse K Reim, Krista L Lanctôt. Biol Psychiatry 2010
Yekta Dowlati, Nathan Herrmann, Walter Swardfager, Helena Liu, Lauren Sham, Elyse K Reim, Krista L Lanctôt. Biol Psychiatry 2010
48
From inflammation to sickness and depression: when the immune system subjugates the brain.
Robert Dantzer, Jason C O'Connor, Gregory G Freund, Rodney W Johnson, Keith W Kelley. Nat Rev Neurosci 2008
Robert Dantzer, Jason C O'Connor, Gregory G Freund, Rodney W Johnson, Keith W Kelley. Nat Rev Neurosci 2008
34
Associations of depression with C-reactive protein, IL-1, and IL-6: a meta-analysis.
M Bryant Howren, Donald M Lamkin, Jerry Suls. Psychosom Med 2009
M Bryant Howren, Donald M Lamkin, Jerry Suls. Psychosom Med 2009
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Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression.
Andrew H Miller, Vladimir Maletic, Charles L Raison. Biol Psychiatry 2009
Andrew H Miller, Vladimir Maletic, Charles L Raison. Biol Psychiatry 2009
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Interleukin (IL)-6, tumour necrosis factor alpha (TNF-α) and soluble interleukin-2 receptors (sIL-2R) are elevated in patients with major depressive disorder: a meta-analysis and meta-regression.
Yang Liu, Roger Chun-Man Ho, Anselm Mak. J Affect Disord 2012
Yang Liu, Roger Chun-Man Ho, Anselm Mak. J Affect Disord 2012
20
Cytokines sing the blues: inflammation and the pathogenesis of depression.
Charles L Raison, Lucile Capuron, Andrew H Miller. Trends Immunol 2006
Charles L Raison, Lucile Capuron, Andrew H Miller. Trends Immunol 2006
20
Increased serum IL-6 and IL-1 receptor antagonist concentrations in major depression and treatment resistant depression.
M Maes, E Bosmans, R De Jongh, G Kenis, E Vandoolaeghe, H Neels. Cytokine 1997
M Maes, E Bosmans, R De Jongh, G Kenis, E Vandoolaeghe, H Neels. Cytokine 1997
19
Evidence for an immune response in major depression: a review and hypothesis.
M Maes. Prog Neuropsychopharmacol Biol Psychiatry 1995
M Maes. Prog Neuropsychopharmacol Biol Psychiatry 1995
17
The new '5-HT' hypothesis of depression: cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression.
M Maes, B E Leonard, A M Myint, M Kubera, R Verkerk. Prog Neuropsychopharmacol Biol Psychiatry 2011
M Maes, B E Leonard, A M Myint, M Kubera, R Verkerk. Prog Neuropsychopharmacol Biol Psychiatry 2011
15
Cytokine production and treatment response in major depressive disorder.
S Lanquillon, J C Krieg, U Bening-Abu-Shach, H Vedder. Neuropsychopharmacology 2000
S Lanquillon, J C Krieg, U Bening-Abu-Shach, H Vedder. Neuropsychopharmacology 2000
15
Interleukin-1 beta: a putative mediator of HPA axis hyperactivity in major depression?
M Maes, E Bosmans, H Y Meltzer, S Scharpé, E Suy. Am J Psychiatry 1993
M Maes, E Bosmans, H Y Meltzer, S Scharpé, E Suy. Am J Psychiatry 1993
15
Depression is an inflammatory disease, but cell-mediated immune activation is the key component of depression.
Michael Maes. Prog Neuropsychopharmacol Biol Psychiatry 2011
Michael Maes. Prog Neuropsychopharmacol Biol Psychiatry 2011
14
Immune disturbances during major depression: upregulated expression of interleukin-2 receptors.
M Maes, E Bosmans, E Suy, C Vandervorst, C De Jonckheere, J Raus. Neuropsychobiology 1990
M Maes, E Bosmans, E Suy, C Vandervorst, C De Jonckheere, J Raus. Neuropsychobiology 1990
14
Depression-related disturbances in mitogen-induced lymphocyte responses and interleukin-1 beta and soluble interleukin-2 receptor production.
M Maes, E Bosmans, E Suy, C Vandervorst, C DeJonckheere, J Raus. Acta Psychiatr Scand 1991
M Maes, E Bosmans, E Suy, C Vandervorst, C DeJonckheere, J Raus. Acta Psychiatr Scand 1991
14
The cyclooxygenase-2 inhibitor celecoxib has therapeutic effects in major depression: results of a double-blind, randomized, placebo controlled, add-on pilot study to reboxetine.
N Müller, M J Schwarz, S Dehning, A Douhe, A Cerovecki, B Goldstein-Müller, I Spellmann, G Hetzel, K Maino, N Kleindienst,[...]. Mol Psychiatry 2006
N Müller, M J Schwarz, S Dehning, A Douhe, A Cerovecki, B Goldstein-Müller, I Spellmann, G Hetzel, K Maino, N Kleindienst,[...]. Mol Psychiatry 2006
13
Associations of C-reactive protein and interleukin-6 with cognitive symptoms of depression: 12-year follow-up of the Whitehall II study.
D Gimeno, M Kivimäki, E J Brunner, M Elovainio, R De Vogli, A Steptoe, M Kumari, G D O Lowe, A Rumley, M G Marmot,[...]. Psychol Med 2009
D Gimeno, M Kivimäki, E J Brunner, M Elovainio, R De Vogli, A Steptoe, M Kumari, G D O Lowe, A Rumley, M G Marmot,[...]. Psychol Med 2009
13
Mechanistic explanations how cell-mediated immune activation, inflammation and oxidative and nitrosative stress pathways and their sequels and concomitants play a role in the pathophysiology of unipolar depression.
Brian Leonard, Michael Maes. Neurosci Biobehav Rev 2012
Brian Leonard, Michael Maes. Neurosci Biobehav Rev 2012
13
A randomized controlled trial of the tumor necrosis factor antagonist infliximab for treatment-resistant depression: the role of baseline inflammatory biomarkers.
Charles L Raison, Robin E Rutherford, Bobbi J Woolwine, Chen Shuo, Pamela Schettler, Daniel F Drake, Ebrahim Haroon, Andrew H Miller. JAMA Psychiatry 2013
Charles L Raison, Robin E Rutherford, Bobbi J Woolwine, Chen Shuo, Pamela Schettler, Daniel F Drake, Ebrahim Haroon, Andrew H Miller. JAMA Psychiatry 2013
13
A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro)degenerative processes in that illness.
Michael Maes, Piotr Galecki, Yong Seun Chang, Michael Berk. Prog Neuropsychopharmacol Biol Psychiatry 2011
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12
Increased plasma concentrations of interleukin-6, soluble interleukin-6, soluble interleukin-2 and transferrin receptor in major depression.
M Maes, H Y Meltzer, E Bosmans, R Bergmans, E Vandoolaeghe, R Ranjan, R Desnyder. J Affect Disord 1995
M Maes, H Y Meltzer, E Bosmans, R Bergmans, E Vandoolaeghe, R Ranjan, R Desnyder. J Affect Disord 1995
12
CRP, IL-6 and depression: a systematic review and meta-analysis of longitudinal studies.
Vyara Valkanova, Klaus P Ebmeier, Charlotte L Allan. J Affect Disord 2013
Vyara Valkanova, Klaus P Ebmeier, Charlotte L Allan. J Affect Disord 2013
12
Paroxetine for the prevention of depression induced by high-dose interferon alfa.
D L Musselman, D H Lawson, J F Gumnick, A K Manatunga, S Penna, R S Goodkin, K Greiner, C B Nemeroff, A H Miller. N Engl J Med 2001
D L Musselman, D H Lawson, J F Gumnick, A K Manatunga, S Penna, R S Goodkin, K Greiner, C B Nemeroff, A H Miller. N Engl J Med 2001
11
Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: evidence for an immune-modulated glutamatergic neurotransmission?
Johann Steiner, Martin Walter, Tomasz Gos, Gilles J Guillemin, Hans-Gert Bernstein, Zoltán Sarnyai, Christian Mawrin, Ralf Brisch, Hendrik Bielau, Louise Meyer zu Schwabedissen,[...]. J Neuroinflammation 2011
Johann Steiner, Martin Walter, Tomasz Gos, Gilles J Guillemin, Hans-Gert Bernstein, Zoltán Sarnyai, Christian Mawrin, Ralf Brisch, Hendrik Bielau, Louise Meyer zu Schwabedissen,[...]. J Neuroinflammation 2011
11
The effect of antidepressant medication treatment on serum levels of inflammatory cytokines: a meta-analysis.
Jonas Hannestad, Nicole DellaGioia, Michael Bloch. Neuropsychopharmacology 2011
Jonas Hannestad, Nicole DellaGioia, Michael Bloch. Neuropsychopharmacology 2011
11
Evidence for a systemic immune activation during depression: results of leukocyte enumeration by flow cytometry in conjunction with monoclonal antibody staining.
M Maes, J Lambrechts, E Bosmans, J Jacobs, E Suy, C Vandervorst, C de Jonckheere, B Minner, J Raus. Psychol Med 1992
M Maes, J Lambrechts, E Bosmans, J Jacobs, E Suy, C Vandervorst, C de Jonckheere, B Minner, J Raus. Psychol Med 1992
11
Evidence for a differential role of HPA-axis function, inflammation and metabolic syndrome in melancholic versus atypical depression.
F Lamers, N Vogelzangs, K R Merikangas, P de Jonge, A T F Beekman, B W J H Penninx. Mol Psychiatry 2013
F Lamers, N Vogelzangs, K R Merikangas, P de Jonge, A T F Beekman, B W J H Penninx. Mol Psychiatry 2013
11
The role of inflammation in depression: from evolutionary imperative to modern treatment target.
Andrew H Miller, Charles L Raison. Nat Rev Immunol 2016
Andrew H Miller, Charles L Raison. Nat Rev Immunol 2016
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The relationship of depression and stressors to immunological assays: a meta-analytic review.
E P Zorrilla, L Luborsky, J R McKay, R Rosenthal, A Houldin, A Tax, R McCorkle, D A Seligman, K Schmidt. Brain Behav Immun 2001
E P Zorrilla, L Luborsky, J R McKay, R Rosenthal, A Houldin, A Tax, R McCorkle, D A Seligman, K Schmidt. Brain Behav Immun 2001
10
Etanercept and clinical outcomes, fatigue, and depression in psoriasis: double-blind placebo-controlled randomised phase III trial.
Stephen Tyring, Alice Gottlieb, Kim Papp, Ken Gordon, Craig Leonardi, Andrea Wang, Deepa Lalla, Michael Woolley, Angelika Jahreis, Ralph Zitnik,[...]. Lancet 2006
Stephen Tyring, Alice Gottlieb, Kim Papp, Ken Gordon, Craig Leonardi, Andrea Wang, Deepa Lalla, Michael Woolley, Angelika Jahreis, Ralph Zitnik,[...]. Lancet 2006
10
When not enough is too much: the role of insufficient glucocorticoid signaling in the pathophysiology of stress-related disorders.
Charles L Raison, Andrew H Miller. Am J Psychiatry 2003
Charles L Raison, Andrew H Miller. Am J Psychiatry 2003
10
The HPA axis in major depression: classical theories and new developments.
Carmine M Pariante, Stafford L Lightman. Trends Neurosci 2008
Carmine M Pariante, Stafford L Lightman. Trends Neurosci 2008
10
Activation of cell-mediated immunity in depression: association with inflammation, melancholia, clinical staging and the fatigue and somatic symptom cluster of depression.
Michael Maes, Ivana Mihaylova, Marta Kubera, Karl Ringel. Prog Neuropsychopharmacol Biol Psychiatry 2012
Michael Maes, Ivana Mihaylova, Marta Kubera, Karl Ringel. Prog Neuropsychopharmacol Biol Psychiatry 2012
10
Cytokine-associated emotional and cognitive disturbances in humans.
A Reichenberg, R Yirmiya, A Schuld, T Kraus, M Haack, A Morag, T Pollmächer. Arch Gen Psychiatry 2001
A Reichenberg, R Yirmiya, A Schuld, T Kraus, M Haack, A Morag, T Pollmächer. Arch Gen Psychiatry 2001
10
Melancholic and atypical major depression--connection between cytokines, psychopathology and treatment.
Bojana Dunjic-Kostic, Maja Ivkovic, Nevena V Radonjic, Natasa D Petronijevic, Maja Pantovic, Aleksandar Damjanovic, Sanja Totic Poznanovic, Aleksandar Jovanovic, Tanja Nikolic, Miroslava Jasovic-Gasic. Prog Neuropsychopharmacol Biol Psychiatry 2013
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Association of serum interleukin 6 and C-reactive protein in childhood with depression and psychosis in young adult life: a population-based longitudinal study.
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Golam M Khandaker, Rebecca M Pearson, Stanley Zammit, Glyn Lewis, Peter B Jones. JAMA Psychiatry 2014
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Cytokines and major depression.
Olga J G Schiepers, Marieke C Wichers, Michael Maes. Prog Neuropsychopharmacol Biol Psychiatry 2005
Olga J G Schiepers, Marieke C Wichers, Michael Maes. Prog Neuropsychopharmacol Biol Psychiatry 2005
9
A prospective evaluation of the directionality of the depression-inflammation relationship.
Jesse C Stewart, Kevin L Rand, Matthew F Muldoon, Thomas W Kamarck. Brain Behav Immun 2009
Jesse C Stewart, Kevin L Rand, Matthew F Muldoon, Thomas W Kamarck. Brain Behav Immun 2009
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The proinflammatory cytokines interleukin-1beta and tumor necrosis factor-alpha activate serotonin transporters.
Chong-Bin Zhu, Randy D Blakely, William A Hewlett. Neuropsychopharmacology 2006
Chong-Bin Zhu, Randy D Blakely, William A Hewlett. Neuropsychopharmacology 2006
9
Pathways underlying neuroprogression in bipolar disorder: focus on inflammation, oxidative stress and neurotrophic factors.
M Berk, F Kapczinski, A C Andreazza, O M Dean, F Giorlando, M Maes, M Yücel, C S Gama, S Dodd, B Dean,[...]. Neurosci Biobehav Rev 2011
M Berk, F Kapczinski, A C Andreazza, O M Dean, F Giorlando, M Maes, M Yücel, C S Gama, S Dodd, B Dean,[...]. Neurosci Biobehav Rev 2011
9
9
Indicators of immune activation in major depression.
A Sluzewska, J Rybakowski, E Bosmans, M Sobieska, R Berghmans, M Maes, K Wiktorowicz. Psychiatry Res 1996
A Sluzewska, J Rybakowski, E Bosmans, M Sobieska, R Berghmans, M Maes, K Wiktorowicz. Psychiatry Res 1996
9
Relationships between lower plasma L-tryptophan levels and immune-inflammatory variables in depression.
M Maes, H Y Meltzer, S Scharpé, E Bosmans, E Suy, I De Meester, J Calabrese, P Cosyns. Psychiatry Res 1993
M Maes, H Y Meltzer, S Scharpé, E Bosmans, E Suy, I De Meester, J Calabrese, P Cosyns. Psychiatry Res 1993
9
Serum concentrations of CRP, IL-6, TNF-α and cortisol in major depressive disorder with melancholic or atypical features.
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9
Role of translocator protein density, a marker of neuroinflammation, in the brain during major depressive episodes.
Elaine Setiawan, Alan A Wilson, Romina Mizrahi, Pablo M Rusjan, Laura Miler, Grazyna Rajkowska, Ivonne Suridjan, James L Kennedy, P Vivien Rekkas, Sylvain Houle,[...]. JAMA Psychiatry 2015
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9
Clinical trial of adjunctive celecoxib treatment in patients with major depression: a double blind and placebo controlled trial.
Shahin Akhondzadeh, Sara Jafari, Firoozeh Raisi, Abbas Ali Nasehi, Aboulfazl Ghoreishi, Bahman Salehi, Soodeh Mohebbi-Rasa, Maedeh Raznahan, Abbas Kamalipour. Depress Anxiety 2009
Shahin Akhondzadeh, Sara Jafari, Firoozeh Raisi, Abbas Ali Nasehi, Aboulfazl Ghoreishi, Bahman Salehi, Soodeh Mohebbi-Rasa, Maedeh Raznahan, Abbas Kamalipour. Depress Anxiety 2009
8
Glucocorticoids, cytokines and brain abnormalities in depression.
Patricia A Zunszain, Christoph Anacker, Annamaria Cattaneo, Livia A Carvalho, Carmine M Pariante. Prog Neuropsychopharmacol Biol Psychiatry 2011
Patricia A Zunszain, Christoph Anacker, Annamaria Cattaneo, Livia A Carvalho, Carmine M Pariante. Prog Neuropsychopharmacol Biol Psychiatry 2011
8
Increased autoimmune activity against 5-HT: a key component of depression that is associated with inflammation and activation of cell-mediated immunity, and with severity and staging of depression.
Michael Maes, Karl Ringel, Marta Kubera, Michael Berk, Janusz Rybakowski. J Affect Disord 2012
Michael Maes, Karl Ringel, Marta Kubera, Michael Berk, Janusz Rybakowski. J Affect Disord 2012
11
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