B Garvik, M Carson, L Hartwell. Mol Cell Biol 1995
Times Cited: 545
Times Cited: 545
Times Cited
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Ten1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13.
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Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13.
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Everything you ever wanted to know about Saccharomyces cerevisiae telomeres: beginning to end.
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The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase alpha and the telomerase-associated est1 protein.
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The Saccharomyces CDC13 protein is a single-strand TG1-3 telomeric DNA-binding protein in vitro that affects telomere behavior in vivo.
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J J Lin, V A Zakian. Proc Natl Acad Sci U S A 1996
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Human CST promotes telomere duplex replication and general replication restart after fork stalling.
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A mutant with a defect in telomere elongation leads to senescence in yeast.
V Lundblad, J W Szostak. Cell 1989
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Cdc13 both positively and negatively regulates telomere replication.
A Chandra, T R Hughes, C I Nugent, V Lundblad. Genes Dev 2001
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EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutants.
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Cdc13 delivers separate complexes to the telomere for end protection and replication.
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E Pennock, K Buckley, V Lundblad. Cell 2001
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Pol12, the B subunit of DNA polymerase alpha, functions in both telomere capping and length regulation.
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Exo1 and Rad24 differentially regulate generation of ssDNA at telomeres of Saccharomyces cerevisiae cdc13-1 mutants.
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The generation of proper constitutive G-tails on yeast telomeres is dependent on the MRX complex.
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Stn1-Ten1 is an Rpa2-Rpa3-like complex at telomeres.
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Telomere length homeostasis is achieved via a switch between telomerase- extendible and -nonextendible states.
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Protection of telomeres by a conserved Stn1-Ten1 complex.
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Telomerase and Tel1p preferentially associate with short telomeres in S. cerevisiae.
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The human CST complex is a terminator of telomerase activity.
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Evolution of CST function in telomere maintenance.
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Saccharomyces telomeres acquire single-strand TG1-3 tails late in S phase.
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An alternative pathway for yeast telomere maintenance rescues est1- senescence.
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Cdk1-dependent phosphorylation of Cdc13 coordinates telomere elongation during cell-cycle progression.
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DNA degradation at unprotected telomeres in yeast is regulated by the CDK1 (Cdc28/Clb) cell-cycle kinase.
Momchil D Vodenicharov, Raymund J Wellinger. Mol Cell 2006
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Telomere capping in non-dividing yeast cells requires Yku and Rap1.
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Identification of the single-strand telomeric DNA binding domain of the Saccharomyces cerevisiae Cdc13 protein.
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Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase α.
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Mammalian telomeres end in a large duplex loop.
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Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiae.
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S C Teng, V A Zakian. Mol Cell Biol 1999
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Multiple pathways regulate 3' overhang generation at S. cerevisiae telomeres.
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CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion.
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Quantitative amplification of single-stranded DNA (QAOS) demonstrates that cdc13-1 mutants generate ssDNA in a telomere to centromere direction.
C Booth, E Griffith, G Brady, D Lydall. Nucleic Acids Res 2001
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Yeast checkpoint genes in DNA damage processing: implications for repair and arrest.
D Lydall, T Weinert. Science 1995
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Distinct roles for yeast Stn1 in telomere capping and telomerase inhibition.
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Est1p as a cell cycle-regulated activator of telomere-bound telomerase.
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Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication.
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CST meets shelterin to keep telomeres in check.
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TLC1: template RNA component of Saccharomyces cerevisiae telomerase.
M S Singer, D E Gottschling. Science 1994
M S Singer, D E Gottschling. Science 1994
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A novel Rap1p-interacting factor, Rif2p, cooperates with Rif1p to regulate telomere length in Saccharomyces cerevisiae.
D Wotton, D Shore. Genes Dev 1997
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Identification of a specific telomere terminal transferase activity in Tetrahymena extracts.
C W Greider, E H Blackburn. Cell 1985
C W Greider, E H Blackburn. Cell 1985
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.