J Caldwell, I Gardner, N Swales. Toxicol Pathol 1995
Times Cited: 40
Times Cited: 40
Times Cited
Times Co-cited
Similarity
Quantitative structure-property relationships in pharmaceutical research - Part 2.
Grover, Singh, Bakshi. 2000
Grover, Singh, Bakshi. 2000
6
Prediction of drug absorption using multivariate statistics.
W J Egan, K M Merz, J J Baldwin. J. Med. Chem. 2000
W J Egan, K M Merz, J J Baldwin. J. Med. Chem. 2000
5
High-throughput screening in drug metabolism and pharmacokinetic support of drug discovery.
R E White. Annu. Rev. Pharmacol. Toxicol. 2000
R E White. Annu. Rev. Pharmacol. Toxicol. 2000
5
Advances in molecular toxicology-towards understanding idiosyncratic drug toxicity.
B K Park, N R Kitteringham, H Powell, M Pirmohamed. Toxicology 2000
B K Park, N R Kitteringham, H Powell, M Pirmohamed. Toxicology 2000
5
Present and future in vitro approaches for drug metabolism.
S Ekins, B J Ring, J Grace, D J McRobie-Belle, S A Wrighton. J Pharmacol Toxicol Methods 2000
S Ekins, B J Ring, J Grace, D J McRobie-Belle, S A Wrighton. J Pharmacol Toxicol Methods 2000
5
Recent advances in the applications of radioisotopes in drug metabolism, toxicology and pharmacokinetics.
D Dalvie. Curr. Pharm. Des. 2000
D Dalvie. Curr. Pharm. Des. 2000
10
ADMET in silico modelling: towards prediction paradise?
Han van de Waterbeemd, Eric Gifford. Nat Rev Drug Discov 2003
Han van de Waterbeemd, Eric Gifford. Nat Rev Drug Discov 2003
5
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings.
C A Lipinski, F Lombardo, B W Dominy, P J Feeney. Adv. Drug Deliv. Rev. 2001
C A Lipinski, F Lombardo, B W Dominy, P J Feeney. Adv. Drug Deliv. Rev. 2001
5
Molecular properties that influence the oral bioavailability of drug candidates.
Daniel F Veber, Stephen R Johnson, Hung-Yuan Cheng, Brian R Smith, Keith W Ward, Kenneth D Kopple. J. Med. Chem. 2002
Daniel F Veber, Stephen R Johnson, Hung-Yuan Cheng, Brian R Smith, Keith W Ward, Kenneth D Kopple. J. Med. Chem. 2002
5
Cachexia: a new definition.
William J Evans, John E Morley, Josep Argilés, Connie Bales, Vickie Baracos, Denis Guttridge, Aminah Jatoi, Kamyar Kalantar-Zadeh, Herbert Lochs, Giovanni Mantovani,[...]. Clin Nutr 2008
William J Evans, John E Morley, Josep Argilés, Connie Bales, Vickie Baracos, Denis Guttridge, Aminah Jatoi, Kamyar Kalantar-Zadeh, Herbert Lochs, Giovanni Mantovani,[...]. Clin Nutr 2008
5
Cachexia as a major underestimated and unmet medical need: facts and numbers.
Stephan von Haehling, Stefan D Anker. J Cachexia Sarcopenia Muscle 2010
Stephan von Haehling, Stefan D Anker. J Cachexia Sarcopenia Muscle 2010
5
Influence of clinicopathological variables on CYP protein expression in human liver.
J George, K Byth, G C Farrell. J. Gastroenterol. Hepatol. 1996
J George, K Byth, G C Farrell. J. Gastroenterol. Hepatol. 1996
10
Pharmacokinetics of methotrexate in Indian children and its relationship to nutritional status.
R V Kumar, S V Gokhale, R Y Ambaye, P A Shetty. Chemotherapy 1987
R V Kumar, S V Gokhale, R Y Ambaye, P A Shetty. Chemotherapy 1987
40
Lean body mass as a predictor of drug dosage. Implications for drug therapy.
D J Morgan, K M Bray. Clin Pharmacokinet 1994
D J Morgan, K M Bray. Clin Pharmacokinet 1994
5
Altered intestinal function in patients with chronic heart failure.
Anja Sandek, Juergen Bauditz, Alexander Swidsinski, Sabine Buhner, Jutta Weber-Eibel, Stephan von Haehling, Wieland Schroedl, Tim Karhausen, Wolfram Doehner, Mathias Rauchhaus,[...]. J. Am. Coll. Cardiol. 2007
Anja Sandek, Juergen Bauditz, Alexander Swidsinski, Sabine Buhner, Jutta Weber-Eibel, Stephan von Haehling, Wieland Schroedl, Tim Karhausen, Wolfram Doehner, Mathias Rauchhaus,[...]. J. Am. Coll. Cardiol. 2007
5
Consensus definition of sarcopenia, cachexia and pre-cachexia: joint document elaborated by Special Interest Groups (SIG) "cachexia-anorexia in chronic wasting diseases" and "nutrition in geriatrics".
M Muscaritoli, S D Anker, J Argilés, Z Aversa, J M Bauer, G Biolo, Y Boirie, I Bosaeus, T Cederholm, P Costelli,[...]. Clin Nutr 2010
M Muscaritoli, S D Anker, J Argilés, Z Aversa, J M Bauer, G Biolo, Y Boirie, I Bosaeus, T Cederholm, P Costelli,[...]. Clin Nutr 2010
5
Body composition measurements during wasting diseases.
C Pichard, U G Kyle. Curr Opin Clin Nutr Metab Care 1998
C Pichard, U G Kyle. Curr Opin Clin Nutr Metab Care 1998
7
A systematic review of pharmacokinetics studies in children with protein-energy malnutrition.
Kazeem A Oshikoya, Helen M Sammons, Imti Choonara. Eur. J. Clin. Pharmacol. 2010
Kazeem A Oshikoya, Helen M Sammons, Imti Choonara. Eur. J. Clin. Pharmacol. 2010
5
Fast, efficient generation of high-quality atomic charges. AM1-BCC model: II. Parameterization and validation.
Araz Jakalian, David B Jack, Christopher I Bayly. J Comput Chem 2002
Araz Jakalian, David B Jack, Christopher I Bayly. J Comput Chem 2002
5
Computation of the binding affinities of catechol-O-methyltransferase inhibitors: multisubstate relative free energy calculations.
P Nuno Palma, Maria João Bonifácio, Ana Isabel Loureiro, Patrício Soares-da-Silva. J Comput Chem 2012
P Nuno Palma, Maria João Bonifácio, Ana Isabel Loureiro, Patrício Soares-da-Silva. J Comput Chem 2012
6
Synthesis, isolation and identification of glucuronides and mercapturic acids of a novel antiparasitic agent, licochalcone A.
L Nadelmann, J Tjørnelund, S H Hansen, C Cornett, U G Sidelmann, U Braumann, E Christensen, S B Christensen. Xenobiotica 1997
L Nadelmann, J Tjørnelund, S H Hansen, C Cornett, U G Sidelmann, U Braumann, E Christensen, S B Christensen. Xenobiotica 1997
33
Effect of silymarin (milk thistle) on liver disease in patients with chronic hepatitis C unsuccessfully treated with interferon therapy: a randomized controlled trial.
Michael W Fried, Victor J Navarro, Nezam Afdhal, Steven H Belle, Abdus S Wahed, Roy L Hawke, Edward Doo, Catherine M Meyers, K Rajender Reddy. JAMA 2012
Michael W Fried, Victor J Navarro, Nezam Afdhal, Steven H Belle, Abdus S Wahed, Roy L Hawke, Edward Doo, Catherine M Meyers, K Rajender Reddy. JAMA 2012
5
Chemical analysis of the Chinese herbal medicine Gan-Cao (licorice).
Qingying Zhang, Min Ye. J Chromatogr A 2009
Qingying Zhang, Min Ye. J Chromatogr A 2009
5
In vitro antimycobacterial and antilegionella activity of licochalcone A from Chinese licorice roots.
Alice Friis-Møller, Ming Chen, Kurt Fuursted, Søren Brøgger Christensen, Arsalan Kharazmi. Planta Med. 2002
Alice Friis-Møller, Ming Chen, Kurt Fuursted, Søren Brøgger Christensen, Arsalan Kharazmi. Planta Med. 2002
5
Phase II drug metabolizing enzymes.
Petra Jancova, Pavel Anzenbacher, Eva Anzenbacherova. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2010
Petra Jancova, Pavel Anzenbacher, Eva Anzenbacherova. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2010
5
Application of the high-performance liquid chromatographic method for separation, purification and characterisation of p-bromophenylacetylurea and its metabolites.
J Xu, J H Lamb, R Jukes, W M Purcell, D E Ray. J. Chromatogr. B Biomed. Sci. Appl. 1999
J Xu, J H Lamb, R Jukes, W M Purcell, D E Ray. J. Chromatogr. B Biomed. Sci. Appl. 1999
100
Synaptophysin immunoreactive axonal swelling in p-bromophenylacetylurea-induced neuropathy.
B S Jortner, K Dyer, A Walton, M Ehrich. Neurotoxicology 1997
B S Jortner, K Dyer, A Walton, M Ehrich. Neurotoxicology 1997
20
Neurotoxic potentiation is related to a metabolic interaction between p-bromophenylacetylurea and phenylmethanesulfonyl fluoride.
J Xu, T Lister, W M Purcell, D E Ray. Toxicol. Appl. Pharmacol. 1999
J Xu, T Lister, W M Purcell, D E Ray. Toxicol. Appl. Pharmacol. 1999
50
Neurotoxicity of halogenated phenylacetylureas is linked to abnormal onset of rapid axonal transport.
H Nagata, S Brimijoin. Brain Res. 1986
H Nagata, S Brimijoin. Brain Res. 1986
11
The experimental neuropathy in rats caused by p-bromophenylacetylurea.
J B Cavanagh, F C Chen, M H Kyu, A Ridley. J. Neurol. Neurosurg. Psychiatry 1968
J B Cavanagh, F C Chen, M H Kyu, A Ridley. J. Neurol. Neurosurg. Psychiatry 1968
3
Slow axonal transport in experimental hypoxia and in neuropathy induced by p-bromophenylacetylurea.
H Nagata, S Brimijoin, P Low, J D Schmelzer. Brain Res. 1987
H Nagata, S Brimijoin, P Low, J D Schmelzer. Brain Res. 1987
10
Theoretical calculation and prediction of brain-blood partitioning of organic solutes using MolSurf parametrization and PLS statistics.
U Norinder, P Sjöberg, T Osterberg. J Pharm Sci 1998
U Norinder, P Sjöberg, T Osterberg. J Pharm Sci 1998
2
A geometric approach to macromolecule-ligand interactions.
I D Kuntz, J M Blaney, S J Oatley, R Langridge, T E Ferrin. J. Mol. Biol. 1982
I D Kuntz, J M Blaney, S J Oatley, R Langridge, T E Ferrin. J. Mol. Biol. 1982
2
Pharmacokinetics and metabolism in early drug discovery.
D A Smith, H van de Waterbeemd. Curr Opin Chem Biol 1999
D A Smith, H van de Waterbeemd. Curr Opin Chem Biol 1999
2
Evaluation of the FLEXX incremental construction algorithm for protein-ligand docking.
B Kramer, M Rarey, T Lengauer. Proteins 1999
B Kramer, M Rarey, T Lengauer. Proteins 1999
2
Feature trees: a new molecular similarity measure based on tree matching.
M Rarey, J S Dixon. J. Comput. Aided Mol. Des. 1998
M Rarey, J S Dixon. J. Comput. Aided Mol. Des. 1998
2
Fast calculation of molecular polar surface area as a sum of fragment-based contributions and its application to the prediction of drug transport properties.
P Ertl, B Rohde, P Selzer. J. Med. Chem. 2000
P Ertl, B Rohde, P Selzer. J. Med. Chem. 2000
2
Preclinical drug metabolism in the age of high-throughput screening: an industrial perspective.
A D Rodrigues. Pharm. Res. 1997
A D Rodrigues. Pharm. Res. 1997
2
Computer design of bioactive molecules: a method for receptor-based de novo ligand design.
J B Moon, W J Howe. Proteins 1991
J B Moon, W J Howe. Proteins 1991
2
Protease inhibitors: current status and future prospects.
D Leung, G Abbenante, D P Fairlie. J. Med. Chem. 2000
D Leung, G Abbenante, D P Fairlie. J. Med. Chem. 2000
2
A general method applicable to the search for similarities in the amino acid sequence of two proteins.
S B Needleman, C D Wunsch. J. Mol. Biol. 1970
S B Needleman, C D Wunsch. J. Mol. Biol. 1970
2
Prediction of the brain-blood distribution of a large set of drugs from structurally derived descriptors using partial least-squares (PLS) modeling.
J M Luco. J Chem Inf Comput Sci 1999
J M Luco. J Chem Inf Comput Sci 1999
2
The characterization of chemical structures using molecular properties. A survey
Livingstone. J Chem Inf Comput Sci 2000
Livingstone. J Chem Inf Comput Sci 2000
2
Can we learn to distinguish between "drug-like" and "nondrug-like" molecules?
A Ajay, W P Walters, M A Murcko. J. Med. Chem. 1998
A Ajay, W P Walters, M A Murcko. J. Med. Chem. 1998
2
Complex synthetic chemical libraries indexed with molecular tags.
M H Ohlmeyer, R N Swanson, L W Dillard, J C Reader, G Asouline, R Kobayashi, M Wigler, W C Still. Proc. Natl. Acad. Sci. U.S.A. 1993
M H Ohlmeyer, R N Swanson, L W Dillard, J C Reader, G Asouline, R Kobayashi, M Wigler, W C Still. Proc. Natl. Acad. Sci. U.S.A. 1993
2
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.