C F Deacon, M A Nauck, M Toft-Nielsen, L Pridal, B Willms, J J Holst. Diabetes 1995
Times Cited: 669
Times Cited: 669
Times Cited
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Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes.
Steven P Marso, Gilbert H Daniels, Kirstine Brown-Frandsen, Peter Kristensen, Johannes F E Mann, Michael A Nauck, Steven E Nissen, Stuart Pocock, Neil R Poulter, Lasse S Ravn,[...]. N Engl J Med 2016
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Glucagon-like peptide-1 7-36: a physiological incretin in man.
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Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes.
Steven P Marso, Stephen C Bain, Agostino Consoli, Freddy G Eliaschewitz, Esteban Jódar, Lawrence A Leiter, Ildiko Lingvay, Julio Rosenstock, Jochen Seufert, Mark L Warren,[...]. N Engl J Med 2016
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Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus.
M A Nauck, M M Heimesaat, C Orskov, J J Holst, R Ebert, W Creutzfeldt. J Clin Invest 1993
M A Nauck, M M Heimesaat, C Orskov, J J Holst, R Ebert, W Creutzfeldt. J Clin Invest 1993
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Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients.
M A Nauck, N Kleine, C Orskov, J J Holst, B Willms, W Creutzfeldt. Diabetologia 1993
M A Nauck, N Kleine, C Orskov, J J Holst, B Willms, W Creutzfeldt. Diabetologia 1993
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A role for glucagon-like peptide-1 in the central regulation of feeding.
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Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV.
T J Kieffer, C H McIntosh, R A Pederson. Endocrinology 1995
T J Kieffer, C H McIntosh, R A Pederson. Endocrinology 1995
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Insulinotropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas.
S Mojsov, G C Weir, J F Habener. J Clin Invest 1987
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Pharmacology, physiology, and mechanisms of incretin hormone action.
Jonathan E Campbell, Daniel J Drucker. Cell Metab 2013
Jonathan E Campbell, Daniel J Drucker. Cell Metab 2013
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The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes.
Daniel J Drucker, Michael A Nauck. Lancet 2006
Daniel J Drucker, Michael A Nauck. Lancet 2006
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The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss.
Anna Secher, Jacob Jelsing, Arian F Baquero, Jacob Hecksher-Sørensen, Michael A Cowley, Louise S Dalbøge, Gitte Hansen, Kevin L Grove, Charles Pyke, Kirsten Raun,[...]. J Clin Invest 2014
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Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo.
C F Deacon, A H Johnsen, J J Holst. J Clin Endocrinol Metab 1995
C F Deacon, A H Johnsen, J J Holst. J Clin Endocrinol Metab 1995
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Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, peptide histidine methionine and is responsible for their degradation in human serum.
R Mentlein, B Gallwitz, W E Schmidt. Eur J Biochem 1993
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Effects of Once-Weekly Exenatide on Cardiovascular Outcomes in Type 2 Diabetes.
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Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus.
Benjamin M Scirica, Deepak L Bhatt, Eugene Braunwald, P Gabriel Steg, Jaime Davidson, Boaz Hirshberg, Peter Ohman, Robert Frederich, Stephen D Wiviott, Elaine B Hoffman,[...]. N Engl J Med 2013
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Effect of Sitagliptin on Cardiovascular Outcomes in Type 2 Diabetes.
Jennifer B Green, M Angelyn Bethel, Paul W Armstrong, John B Buse, Samuel S Engel, Jyotsna Garg, Robert Josse, Keith D Kaufman, Joerg Koglin, Scott Korn,[...]. N Engl J Med 2015
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Lixisenatide in Patients with Type 2 Diabetes and Acute Coronary Syndrome.
Marc A Pfeffer, Brian Claggett, Rafael Diaz, Kenneth Dickstein, Hertzel C Gerstein, Lars V Køber, Francesca C Lawson, Lin Ping, Xiaodan Wei, Eldrin F Lewis,[...]. N Engl J Med 2015
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Glucagon-like peptide-1-(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine.
L Hansen, C F Deacon, C Orskov, J J Holst. Endocrinology 1999
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Alogliptin after acute coronary syndrome in patients with type 2 diabetes.
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Truncated glucagon-like peptide I, an insulin-releasing hormone from the distal gut.
J J Holst, C Orskov, O V Nielsen, T W Schwartz. FEBS Lett 1987
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Reduced incretin effect in type 2 (non-insulin-dependent) diabetes.
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A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management.
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Distribution of glucagon-like peptide-1 and other preproglucagon-derived peptides in the rat hypothalamus and brainstem.
P J Larsen, M Tang-Christensen, J J Holst, C Orskov. Neuroscience 1997
P J Larsen, M Tang-Christensen, J J Holst, C Orskov. Neuroscience 1997
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Defective amplification of the late phase insulin response to glucose by GIP in obese Type II diabetic patients.
T Vilsbøll, T Krarup, S Madsbad, J J Holst. Diabetologia 2002
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Stimulation of insulin secretion by gastric inhibitory polypeptide in man.
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Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans.
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Incretin effects of increasing glucose loads in man calculated from venous insulin and C-peptide responses.
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Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes.
P V Højberg, T Vilsbøll, R Rabøl, F K Knop, M Bache, T Krarup, J J Holst, S Madsbad. Diabetologia 2009
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Mechanisms of Action and Therapeutic Application of Glucagon-like Peptide-1.
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Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide I in humans.
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Dipeptidyl-peptidase IV (CD26)--role in the inactivation of regulatory peptides.
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Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes.
Bernard Zinman, Christoph Wanner, John M Lachin, David Fitchett, Erich Bluhmki, Stefan Hantel, Michaela Mattheus, Theresa Devins, Odd Erik Johansen, Hans J Woerle,[...]. N Engl J Med 2015
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Hamster preproglucagon contains the sequence of glucagon and two related peptides.
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Neuronal GLP1R mediates liraglutide's anorectic but not glucose-lowering effect.
Stephanie Sisley, Ruth Gutierrez-Aguilar, Michael Scott, David A D'Alessio, Darleen A Sandoval, Randy J Seeley. J Clin Invest 2014
Stephanie Sisley, Ruth Gutierrez-Aguilar, Michael Scott, David A D'Alessio, Darleen A Sandoval, Randy J Seeley. J Clin Invest 2014
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Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial.
Adrian F Hernandez, Jennifer B Green, Salim Janmohamed, Ralph B D'Agostino, Christopher B Granger, Nigel P Jones, Lawrence A Leiter, Anne E Rosenberg, Kristina N Sigmon, Matthew C Somerville,[...]. Lancet 2018
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Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line.
D J Drucker, J Philippe, S Mojsov, W L Chick, J F Habener. Proc Natl Acad Sci U S A 1987
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Glucagon-like peptides GLP-1 and GLP-2, predicted products of the glucagon gene, are secreted separately from pig small intestine but not pancreas.
C Orskov, J J Holst, S Knuhtsen, F G Baldissera, S S Poulsen, O V Nielsen. Endocrinology 1986
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Effect of single oral doses of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on incretin and plasma glucose levels after an oral glucose tolerance test in patients with type 2 diabetes.
Gary A Herman, Arthur Bergman, Catherine Stevens, Paul Kotey, Bingming Yi, Peng Zhao, Bruno Dietrich, George Golor, Andreas Schrodter, Bart Keymeulen,[...]. J Clin Endocrinol Metab 2006
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Comparative review of dipeptidyl peptidase-4 inhibitors and sulphonylureas.
C F Deacon, H E Lebovitz. Diabetes Obes Metab 2016
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Pharmacology, physiology, and mechanisms of action of dipeptidyl peptidase-4 inhibitors.
Erin E Mulvihill, Daniel J Drucker. Endocr Rev 2014
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Quantification of the Contribution of GLP-1 to Mediating Insulinotropic Effects of DPP-4 Inhibition With Vildagliptin in Healthy Subjects and Patients With Type 2 Diabetes Using Exendin [9-39] as a GLP-1 Receptor Antagonist.
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Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide 1 in the anesthetized pig.
C F Deacon, T E Hughes, J J Holst. Diabetes 1998
C F Deacon, T E Hughes, J J Holst. Diabetes 1998
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Reduced postprandial concentrations of intact biologically active glucagon-like peptide 1 in type 2 diabetic patients.
T Vilsbøll, T Krarup, C F Deacon, S Madsbad, J J Holst. Diabetes 2001
T Vilsbøll, T Krarup, C F Deacon, S Madsbad, J J Holst. Diabetes 2001
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Minireview: Glucagon-like peptides regulate cell proliferation and apoptosis in the pancreas, gut, and central nervous system.
P L Brubaker, D J Drucker. Endocrinology 2004
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