A citation-based method for searching scientific literature

Q Chen, A Fischer, J D Reagan, L J Yan, B N Ames. Proc Natl Acad Sci U S A 1995
Times Cited: 423







List of co-cited articles
878 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


A biomarker that identifies senescent human cells in culture and in aging skin in vivo.
G P Dimri, X Lee, G Basile, M Acosta, G Scott, C Roskelley, E E Medrano, M Linskens, I Rubelj, O Pereira-Smith. Proc Natl Acad Sci U S A 1995
36

The serial cultivation of human diploid cell strains.
L HAYFLICK, P S MOORHEAD. Exp Cell Res 1961
34


Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor.
Jean-Philippe Coppé, Christopher K Patil, Francis Rodier, Yu Sun, Denise P Muñoz, Joshua Goldstein, Peter S Nelson, Pierre-Yves Desprez, Judith Campisi. PLoS Biol 2008
25

The role of senescent cells in ageing.
Jan M van Deursen. Nature 2014
926
22

Cellular senescence: when bad things happen to good cells.
Judith Campisi, Fabrizio d'Adda di Fagagna. Nat Rev Mol Cell Biol 2007
21

The senescence-associated secretory phenotype: the dark side of tumor suppression.
Jean-Philippe Coppé, Pierre-Yves Desprez, Ana Krtolica, Judith Campisi. Annu Rev Pathol 2010
20

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders.
Darren J Baker, Tobias Wijshake, Tamar Tchkonia, Nathan K LeBrasseur, Bennett G Childs, Bart van de Sluis, James L Kirkland, Jan M van Deursen. Nature 2011
20

Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts.
Simona Parrinello, Enrique Samper, Ana Krtolica, Joshua Goldstein, Simon Melov, Judith Campisi. Nat Cell Biol 2003
732
19

Chemokine signaling via the CXCR2 receptor reinforces senescence.
Juan C Acosta, Ana O'Loghlen, Ana Banito, Maria V Guijarro, Arnaud Augert, Selina Raguz, Marzia Fumagalli, Marco Da Costa, Celia Brown, Nikolay Popov,[...]. Cell 2008
926
19

An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA.
Marco Demaria, Naoko Ohtani, Sameh A Youssef, Francis Rodier, Wendy Toussaint, James R Mitchell, Remi-Martin Laberge, Jan Vijg, Harry Van Steeg, Martijn E T Dollé,[...]. Dev Cell 2014
647
19

Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan.
Darren J Baker, Bennett G Childs, Matej Durik, Melinde E Wijers, Cynthia J Sieben, Jian Zhong, Rachel A Saltness, Karthik B Jeganathan, Grace Casaclang Verzosa, Abdulmohammad Pezeshki,[...]. Nature 2016
19

Cellular senescence: from physiology to pathology.
Daniel Muñoz-Espín, Manuel Serrano. Nat Rev Mol Cell Biol 2014
972
18


Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints.
Jirina Bartkova, Nousin Rezaei, Michalis Liontos, Panagiotis Karakaidos, Dimitris Kletsas, Natalia Issaeva, Leandros-Vassilios F Vassiliou, Evangelos Kolettas, Katerina Niforou, Vassilis C Zoumpourlis,[...]. Nature 2006
18

Senescence of activated stellate cells limits liver fibrosis.
Valery Krizhanovsky, Monica Yon, Ross A Dickins, Stephen Hearn, Janelle Simon, Cornelius Miething, Herman Yee, Lars Zender, Scott W Lowe. Cell 2008
981
18

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.
Francis Rodier, Jean-Philippe Coppé, Christopher K Patil, Wieteke A M Hoeijmakers, Denise P Muñoz, Saba R Raza, Adam Freund, Eric Campeau, Albert R Davalos, Judith Campisi. Nat Cell Biol 2009
17

A complex secretory program orchestrated by the inflammasome controls paracrine senescence.
Juan Carlos Acosta, Ana Banito, Torsten Wuestefeld, Athena Georgilis, Peggy Janich, Jennifer P Morton, Dimitris Athineos, Tae-Won Kang, Felix Lasitschka, Mindaugas Andrulis,[...]. Nat Cell Biol 2013
755
17

BRAFE600-associated senescence-like cell cycle arrest of human naevi.
Chrysiis Michaloglou, Liesbeth C W Vredeveld, Maria S Soengas, Christophe Denoyelle, Thomas Kuilman, Chantal M A M van der Horst, Donné M Majoor, Jerry W Shay, Wolter J Mooi, Daniel S Peeper. Nature 2005
17

The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.
Yi Zhu, Tamara Tchkonia, Tamar Pirtskhalava, Adam C Gower, Husheng Ding, Nino Giorgadze, Allyson K Palmer, Yuji Ikeno, Gene B Hubbard, Marc Lenburg,[...]. Aging Cell 2015
649
17

Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence.
Masashi Narita, Sabrina Nũnez, Edith Heard, Masako Narita, Athena W Lin, Stephen A Hearn, David L Spector, Gregory J Hannon, Scott W Lowe. Cell 2003
17

Senescence is a developmental mechanism that contributes to embryonic growth and patterning.
Mekayla Storer, Alba Mas, Alexandre Robert-Moreno, Matteo Pecoraro, M Carmen Ortells, Valeria Di Giacomo, Reut Yosef, Noam Pilpel, Valery Krizhanovsky, James Sharpe,[...]. Cell 2013
489
16

Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging.
A Krtolica, S Parrinello, S Lockett, P Y Desprez, J Campisi. Proc Natl Acad Sci U S A 2001
894
16

Four faces of cellular senescence.
Francis Rodier, Judith Campisi. J Cell Biol 2011
16

Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network.
Thomas Kuilman, Chrysiis Michaloglou, Liesbeth C W Vredeveld, Sirith Douma, Remco van Doorn, Christophe J Desmet, Lucien A Aarden, Wolter J Mooi, Daniel S Peeper. Cell 2008
15

Tumour biology: senescence in premalignant tumours.
Manuel Collado, Jesús Gil, Alejo Efeyan, Carmen Guerra, Alberto J Schuhmacher, Marta Barradas, Alberto Benguría, Angel Zaballos, Juana M Flores, Mariano Barbacid,[...]. Nature 2005
943
15

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas.
Wen Xue, Lars Zender, Cornelius Miething, Ross A Dickins, Eva Hernando, Valery Krizhanovsky, Carlos Cordon-Cardo, Scott W Lowe. Nature 2007
15

Programmed cell senescence during mammalian embryonic development.
Daniel Muñoz-Espín, Marta Cañamero, Antonio Maraver, Gonzalo Gómez-López, Julio Contreras, Silvia Murillo-Cuesta, Alfonso Rodríguez-Baeza, Isabel Varela-Nieto, Jesús Ruberte, Manuel Collado,[...]. Cell 2013
590
14

Extension of life-span by introduction of telomerase into normal human cells.
A G Bodnar, M Ouellette, M Frolkis, S E Holt, C P Chiu, G B Morin, C B Harley, J W Shay, S Lichtsteiner, W E Wright. Science 1998
14

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis.
Zhenbang Chen, Lloyd C Trotman, David Shaffer, Hui-Kuan Lin, Zohar A Dotan, Masaru Niki, Jason A Koutcher, Howard I Scher, Thomas Ludwig, William Gerald,[...]. Nature 2005
14

Senescence surveillance of pre-malignant hepatocytes limits liver cancer development.
Tae-Won Kang, Tetyana Yevsa, Norman Woller, Lisa Hoenicke, Torsten Wuestefeld, Daniel Dauch, Anja Hohmeyer, Marcus Gereke, Ramona Rudalska, Anna Potapova,[...]. Nature 2011
705
14

Telomeres shorten during ageing of human fibroblasts.
C B Harley, A B Futcher, C W Greider. Nature 1990
13

Oncogene-induced senescence as an initial barrier in lymphoma development.
Melanie Braig, Soyoung Lee, Christoph Loddenkemper, Cornelia Rudolph, Antoine H F M Peters, Brigitte Schlegelberger, Harald Stein, Bernd Dörken, Thomas Jenuwein, Clemens A Schmitt. Nature 2005
783
13

MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation.
Remi-Martin Laberge, Yu Sun, Arturo V Orjalo, Christopher K Patil, Adam Freund, Lili Zhou, Samuel C Curran, Albert R Davalos, Kathleen A Wilson-Edell, Su Liu,[...]. Nat Cell Biol 2015
433
13

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication.
Raffaella Di Micco, Marzia Fumagalli, Angelo Cicalese, Sara Piccinin, Patrizia Gasparini, Chiara Luise, Catherine Schurra, Massimiliano Garre', Paolo Giovanni Nuciforo, Aaron Bensimon,[...]. Nature 2006
12

Aging, cellular senescence, and cancer.
Judith Campisi. Annu Rev Physiol 2013
12

Feedback between p21 and reactive oxygen production is necessary for cell senescence.
João F Passos, Glyn Nelson, Chunfang Wang, Torsten Richter, Cedric Simillion, Carole J Proctor, Satomi Miwa, Sharon Olijslagers, Jennifer Hallinan, Anil Wipat,[...]. Mol Syst Biol 2010
439
11

The essence of senescence.
Thomas Kuilman, Chrysiis Michaloglou, Wolter J Mooi, Daniel S Peeper. Genes Dev 2010
11

Senescence and apoptosis: dueling or complementary cell fates?
Bennett G Childs, Darren J Baker, James L Kirkland, Judith Campisi, Jan M van Deursen. EMBO Rep 2014
309
11

Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice.
Jianhui Chang, Yingying Wang, Lijian Shao, Remi-Martin Laberge, Marco Demaria, Judith Campisi, Krishnamurthy Janakiraman, Norman E Sharpless, Sheng Ding, Wei Feng,[...]. Nat Med 2016
620
11

Cellular senescence in cancer and aging.
Manuel Collado, Maria A Blasco, Manuel Serrano. Cell 2007
991
10

DNA damage is able to induce senescence in tumor cells in vitro and in vivo.
Robert H te Poele, Andrei L Okorokov, Lesley Jardine, Jeffrey Cummings, Simon P Joel. Cancer Res 2002
409
10

Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity.
Yuchen Chien, Claudio Scuoppo, Xiaowo Wang, Xueping Fang, Brian Balgley, Jessica E Bolden, Prem Premsrirut, Weijun Luo, Agustin Chicas, Cheng S Lee,[...]. Genes Dev 2011
440
10

Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species.
A C Lee, B E Fenster, H Ito, K Takeda, N S Bae, T Hirai, Z X Yu, V J Ferrans, B H Howard, T Finkel. J Biol Chem 1999
425
10


The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
10

Cellular senescence in aging and age-related disease: from mechanisms to therapy.
Bennett G Childs, Matej Durik, Darren J Baker, Jan M van Deursen. Nat Med 2015
691
10

JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age.
Ming Xu, Tamara Tchkonia, Husheng Ding, Mikolaj Ogrodnik, Ellen R Lubbers, Tamar Pirtskhalava, Thomas A White, Kurt O Johnson, Michael B Stout, Vojtech Mezera,[...]. Proc Natl Acad Sci U S A 2015
256
10

Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging.
Marjolein P Baar, Renata M C Brandt, Diana A Putavet, Julian D D Klein, Kasper W J Derks, Benjamin R M Bourgeois, Sarah Stryeck, Yvonne Rijksen, Hester van Willigenburg, Danny A Feijtel,[...]. Cell 2017
463
10



Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.