H Hsu, J Xiong, D V Goeddel. Cell 1995
Times Cited: 1675
Times Cited: 1675
Times Cited
Times Co-cited
Similarity
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes.
Olivier Micheau, Jürg Tschopp. Cell 2003
Olivier Micheau, Jürg Tschopp. Cell 2003
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TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex.
H Hsu, J Huang, H B Shu, V Baichwal, D V Goeddel. Immunity 1996
H Hsu, J Huang, H B Shu, V Baichwal, D V Goeddel. Immunity 1996
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Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction.
Tobias L Haas, Christoph H Emmerich, Björn Gerlach, Anna C Schmukle, Stefanie M Cordier, Eva Rieser, Rebecca Feltham, James Vince, Uwe Warnken, Till Wenger,[...]. Mol Cell 2009
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TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways.
H Hsu, H B Shu, M G Pan, D V Goeddel. Cell 1996
H Hsu, H B Shu, M G Pan, D V Goeddel. Cell 1996
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cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination.
Mathieu J M Bertrand, Snezana Milutinovic, Kathleen M Dickson, Wai Chi Ho, Alain Boudreault, Jon Durkin, John W Gillard, James B Jaquith, Stephen J Morris, Philip A Barker. Mol Cell 2008
Mathieu J M Bertrand, Snezana Milutinovic, Kathleen M Dickson, Wai Chi Ho, Alain Boudreault, Jon Durkin, John W Gillard, James B Jaquith, Stephen J Morris, Philip A Barker. Mol Cell 2008
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Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase.
Liming Sun, Huayi Wang, Zhigao Wang, Sudan He, She Chen, Daohong Liao, Lai Wang, Jiacong Yan, Weilong Liu, Xiaoguang Lei,[...]. Cell 2012
Liming Sun, Huayi Wang, Zhigao Wang, Sudan He, She Chen, Daohong Liao, Lai Wang, Jiacong Yan, Weilong Liu, Xiaoguang Lei,[...]. Cell 2012
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TNF-alpha induces two distinct caspase-8 activation pathways.
Lai Wang, Fenghe Du, Xiaodong Wang. Cell 2008
Lai Wang, Fenghe Du, Xiaodong Wang. Cell 2008
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Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha.
Sudan He, Lai Wang, Lin Miao, Tao Wang, Fenghe Du, Liping Zhao, Xiaodong Wang. Cell 2009
Sudan He, Lai Wang, Lin Miao, Tao Wang, Fenghe Du, Liping Zhao, Xiaodong Wang. Cell 2009
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Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO.
Chee-Kwee Ea, Li Deng, Zong-Ping Xia, Gabriel Pineda, Zhijian J Chen. Mol Cell 2006
Chee-Kwee Ea, Li Deng, Zong-Ping Xia, Gabriel Pineda, Zhijian J Chen. Mol Cell 2006
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Linear ubiquitination prevents inflammation and regulates immune signalling.
Björn Gerlach, Stefanie M Cordier, Anna C Schmukle, Christoph H Emmerich, Eva Rieser, Tobias L Haas, Andrew I Webb, James A Rickard, Holly Anderton, Wendy W-L Wong,[...]. Nature 2011
Björn Gerlach, Stefanie M Cordier, Anna C Schmukle, Christoph H Emmerich, Eva Rieser, Tobias L Haas, Andrew I Webb, James A Rickard, Holly Anderton, Wendy W-L Wong,[...]. Nature 2011
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Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation.
Young Sik Cho, Sreerupa Challa, David Moquin, Ryan Genga, Tathagat Dutta Ray, Melissa Guildford, Francis Ka-Ming Chan. Cell 2009
Young Sik Cho, Sreerupa Challa, David Moquin, Ryan Genga, Tathagat Dutta Ray, Melissa Guildford, Francis Ka-Ming Chan. Cell 2009
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A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells.
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R M Locksley, N Killeen, M J Lenardo. Cell 2001
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TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (tnf) to efficiently activate nf-{kappa}b and to prevent tnf-induced apoptosis.
James E Vince, Delara Pantaki, Rebecca Feltham, Peter D Mace, Stephanie M Cordier, Anna C Schmukle, Angelina J Davidson, Bernard A Callus, Wendy Wei-Lynn Wong, Ian E Gentle,[...]. J Biol Chem 2009
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The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins.
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TNF and TNF-receptors: From mediators of cell death and inflammation to therapeutic giants - past, present and future.
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c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation.
Eugene Varfolomeev, Tatiana Goncharov, Anna V Fedorova, Jasmin N Dynek, Kerry Zobel, Kurt Deshayes, Wayne J Fairbrother, Domagoj Vucic. J Biol Chem 2008
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The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex.
H B Shu, M Takeuchi, D V Goeddel. Proc Natl Acad Sci U S A 1996
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c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling.
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cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms.
Maria Feoktistova, Peter Geserick, Beate Kellert, Diana Panayotova Dimitrova, Claudia Langlais, Mike Hupe, Kelvin Cain, Marion MacFarlane, Georg Häcker, Martin Leverkus. Mol Cell 2011
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12
Mixed lineage kinase domain-like protein MLKL causes necrotic membrane disruption upon phosphorylation by RIP3.
Huayi Wang, Liming Sun, Lijing Su, Josep Rizo, Lei Liu, Li-Feng Wang, Fu-Sheng Wang, Xiaodong Wang. Mol Cell 2014
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Molecular mechanisms of necroptosis: an ordered cellular explosion.
Peter Vandenabeele, Lorenzo Galluzzi, Tom Vanden Berghe, Guido Kroemer. Nat Rev Mol Cell Biol 2010
Peter Vandenabeele, Lorenzo Galluzzi, Tom Vanden Berghe, Guido Kroemer. Nat Rev Mol Cell Biol 2010
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Identification of RIP1 kinase as a specific cellular target of necrostatins.
Alexei Degterev, Junichi Hitomi, Megan Germscheid, Irene L Ch'en, Olga Korkina, Xin Teng, Derek Abbott, Gregory D Cuny, Chengye Yuan, Gerhard Wagner,[...]. Nat Chem Biol 2008
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TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains.
Atsuhiro Kanayama, Rashu B Seth, Lijun Sun, Chee-Kwee Ea, Mei Hong, Abdullah Shaito, Yu-Hsin Chiu, Li Deng, Zhijian J Chen. Mol Cell 2004
Atsuhiro Kanayama, Rashu B Seth, Lijun Sun, Chee-Kwee Ea, Mei Hong, Abdullah Shaito, Yu-Hsin Chiu, Li Deng, Zhijian J Chen. Mol Cell 2004
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Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis.
Andrew Oberst, Christopher P Dillon, Ricardo Weinlich, Laura L McCormick, Patrick Fitzgerald, Cristina Pop, Razq Hakem, Guy S Salvesen, Douglas R Green. Nature 2011
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Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation.
Fuminori Tokunaga, Shin-ichi Sakata, Yasushi Saeki, Yoshinori Satomi, Takayoshi Kirisako, Kiyoko Kamei, Tomoko Nakagawa, Michiko Kato, Shigeo Murata, Shoji Yamaoka,[...]. Nat Cell Biol 2009
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NF-κB-Independent Role of IKKα/IKKβ in Preventing RIPK1 Kinase-Dependent Apoptotic and Necroptotic Cell Death during TNF Signaling.
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Yves Dondelinger, Sandrine Jouan-Lanhouet, Tatyana Divert, Emilie Theatre, John Bertin, Peter J Gough, Piero Giansanti, Albert J R Heck, Emmanuel Dejardin, Peter Vandenabeele,[...]. Mol Cell 2015
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The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis.
Jixi Li, Thomas McQuade, Ansgar B Siemer, Johanna Napetschnig, Kenta Moriwaki, Yu-Shan Hsiao, Ermelinda Damko, David Moquin, Thomas Walz, Ann McDermott,[...]. Cell 2012
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The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism.
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James M Murphy, Peter E Czabotar, Joanne M Hildebrand, Isabelle S Lucet, Jian-Guo Zhang, Silvia Alvarez-Diaz, Rowena Lewis, Najoua Lalaoui, Donald Metcalf, Andrew I Webb,[...]. Immunity 2013
10
Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis.
Zhenyu Cai, Siriporn Jitkaew, Jie Zhao, Hsueh-Cheng Chiang, Swati Choksi, Jie Liu, Yvona Ward, Ling-Gang Wu, Zheng-Gang Liu. Nat Cell Biol 2014
Zhenyu Cai, Siriporn Jitkaew, Jie Zhao, Hsueh-Cheng Chiang, Swati Choksi, Jie Liu, Yvona Ward, Ling-Gang Wu, Zheng-Gang Liu. Nat Cell Biol 2014
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Regulation of tumour necrosis factor signalling: live or let die.
Dirk Brenner, Heiko Blaser, Tak W Mak. Nat Rev Immunol 2015
Dirk Brenner, Heiko Blaser, Tak W Mak. Nat Rev Immunol 2015
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Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
Lorenzo Galluzzi, Ilio Vitale, Stuart A Aaronson, John M Abrams, Dieter Adam, Patrizia Agostinis, Emad S Alnemri, Lucia Altucci, Ivano Amelio, David W Andrews,[...]. Cell Death Differ 2018
Lorenzo Galluzzi, Ilio Vitale, Stuart A Aaronson, John M Abrams, Dieter Adam, Patrizia Agostinis, Emad S Alnemri, Lucia Altucci, Ivano Amelio, David W Andrews,[...]. Cell Death Differ 2018
10
Ubiquitination of RIP is required for tumor necrosis factor alpha-induced NF-kappaB activation.
Hongxiu Li, Masayuki Kobayashi, Marzenna Blonska, Yun You, Xin Lin. J Biol Chem 2006
Hongxiu Li, Masayuki Kobayashi, Marzenna Blonska, Yun You, Xin Lin. J Biol Chem 2006
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The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs.
Tencho Tenev, Katiuscia Bianchi, Maurice Darding, Meike Broemer, Claudia Langlais, Fredrik Wallberg, Anna Zachariou, Juanita Lopez, Marion MacFarlane, Kelvin Cain,[...]. Mol Cell 2011
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The function of TRADD in signaling through tumor necrosis factor receptor 1 and TRIF-dependent Toll-like receptors.
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Scott B Berger, Viera Kasparcova, Sandy Hoffman, Barb Swift, Lauren Dare, Michelle Schaeffer, Carol Capriotti, Michael Cook, Joshua Finger, Angela Hughes-Earle,[...]. J Immunol 2014
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Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease.
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MLKL compromises plasma membrane integrity by binding to phosphatidylinositol phosphates.
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Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury.
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Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis.
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TAK1 is a ubiquitin-dependent kinase of MKK and IKK.
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Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule.
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RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis.
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RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.