M Furuse, M Itoh, T Hirase, A Nagafuchi, S Yonemura, S Tsukita, S Tsukita. J Cell Biol 1994
Times Cited: 751
Times Cited: 751
Times Cited
Times Co-cited
Similarity
Occludin: a novel integral membrane protein localizing at tight junctions.
M Furuse, T Hirase, M Itoh, A Nagafuchi, S Yonemura, S Tsukita, S Tsukita. J Cell Biol 1993
M Furuse, T Hirase, M Itoh, A Nagafuchi, S Yonemura, S Tsukita, S Tsukita. J Cell Biol 1993
27
Complex phenotype of mice lacking occludin, a component of tight junction strands.
M Saitou, M Furuse, H Sasaki, J D Schulzke, M Fromm, H Takano, T Noda, S Tsukita. Mol Biol Cell 2000
M Saitou, M Furuse, H Sasaki, J D Schulzke, M Fromm, H Takano, T Noda, S Tsukita. Mol Biol Cell 2000
21
The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton.
A S Fanning, B J Jameson, L A Jesaitis, J M Anderson. J Biol Chem 1998
A S Fanning, B J Jameson, L A Jesaitis, J M Anderson. J Biol Chem 1998
21
Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins.
M Itoh, M Furuse, K Morita, K Kubota, M Saitou, S Tsukita. J Cell Biol 1999
M Itoh, M Furuse, K Morita, K Kubota, M Saitou, S Tsukita. J Cell Biol 1999
20
Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia.
B R Stevenson, J D Siliciano, M S Mooseker, D A Goodenough. J Cell Biol 1986
B R Stevenson, J D Siliciano, M S Mooseker, D A Goodenough. J Cell Biol 1986
19
Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin.
M Furuse, K Fujita, T Hiiragi, K Fujimoto, S Tsukita. J Cell Biol 1998
M Furuse, K Fujita, T Hiiragi, K Fujimoto, S Tsukita. J Cell Biol 1998
16
Tight junction-associated MARVEL proteins marveld3, tricellulin, and occludin have distinct but overlapping functions.
David R Raleigh, Amanda M Marchiando, Yong Zhang, Le Shen, Hiroyuki Sasaki, Yingmin Wang, Manyuan Long, Jerrold R Turner. Mol Biol Cell 2010
David R Raleigh, Amanda M Marchiando, Yong Zhang, Le Shen, Hiroyuki Sasaki, Yingmin Wang, Manyuan Long, Jerrold R Turner. Mol Biol Cell 2010
13
Occludin S408 phosphorylation regulates tight junction protein interactions and barrier function.
David R Raleigh, Devin M Boe, Dan Yu, Christopher R Weber, Amanda M Marchiando, Emily M Bradford, Yingmin Wang, Licheng Wu, Eveline E Schneeberger, Le Shen,[...]. J Cell Biol 2011
David R Raleigh, Devin M Boe, Dan Yu, Christopher R Weber, Amanda M Marchiando, Emily M Bradford, Yingmin Wang, Licheng Wu, Eveline E Schneeberger, Le Shen,[...]. J Cell Biol 2011
12
Tight junction pore and leak pathways: a dynamic duo.
Le Shen, Christopher R Weber, David R Raleigh, Dan Yu, Jerrold R Turner. Annu Rev Physiol 2011
Le Shen, Christopher R Weber, David R Raleigh, Dan Yu, Jerrold R Turner. Annu Rev Physiol 2011
11
Involvement of ZO-1 in cadherin-based cell adhesion through its direct binding to alpha catenin and actin filaments.
M Itoh, A Nagafuchi, S Moroi, S Tsukita. J Cell Biol 1997
M Itoh, A Nagafuchi, S Moroi, S Tsukita. J Cell Biol 1997
10
ZO-1 and ZO-2 independently determine where claudins are polymerized in tight-junction strand formation.
Kazuaki Umeda, Junichi Ikenouchi, Sayaka Katahira-Tayama, Kyoko Furuse, Hiroyuki Sasaki, Mayumi Nakayama, Takeshi Matsui, Sachiko Tsukita, Mikio Furuse, Shoichiro Tsukita. Cell 2006
Kazuaki Umeda, Junichi Ikenouchi, Sayaka Katahira-Tayama, Kyoko Furuse, Hiroyuki Sasaki, Mayumi Nakayama, Takeshi Matsui, Sachiko Tsukita, Mikio Furuse, Shoichiro Tsukita. Cell 2006
10
Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells.
Salah Amasheh, Noga Meiri, Alfred H Gitter, Torsten Schöneberg, Joachim Mankertz, Jörg D Schulzke, Michael Fromm. J Cell Sci 2002
Salah Amasheh, Noga Meiri, Alfred H Gitter, Torsten Schöneberg, Joachim Mankertz, Jörg D Schulzke, Michael Fromm. J Cell Sci 2002
10
Interaction of junctional adhesion molecule with the tight junction components ZO-1, cingulin, and occludin.
G Bazzoni, O M Martinez-Estrada, F Orsenigo, M Cordenonsi, S Citi, E Dejana. J Biol Chem 2000
G Bazzoni, O M Martinez-Estrada, F Orsenigo, M Cordenonsi, S Citi, E Dejana. J Biol Chem 2000
10
Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein.
M S Balda, J A Whitney, C Flores, S González, M Cereijido, K Matter. J Cell Biol 1996
M S Balda, J A Whitney, C Flores, S González, M Cereijido, K Matter. J Cell Biol 1996
10
Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration.
I Martìn-Padura, S Lostaglio, M Schneemann, L Williams, M Romano, P Fruscella, C Panzeri, A Stoppacciaro, L Ruco, A Villa,[...]. J Cell Biol 1998
I Martìn-Padura, S Lostaglio, M Schneemann, L Williams, M Romano, P Fruscella, C Panzeri, A Stoppacciaro, L Ruco, A Villa,[...]. J Cell Biol 1998
10
Epithelial transport and barrier function in occludin-deficient mice.
J D Schulzke, A H Gitter, J Mankertz, S Spiegel, U Seidler, S Amasheh, M Saitou, S Tsukita, M Fromm. Biochim Biophys Acta 2005
J D Schulzke, A H Gitter, J Mankertz, S Spiegel, U Seidler, S Amasheh, M Saitou, S Tsukita, M Fromm. Biochim Biophys Acta 2005
9
Deficiency of zonula occludens-1 causes embryonic lethal phenotype associated with defected yolk sac angiogenesis and apoptosis of embryonic cells.
Tatsuya Katsuno, Kazuaki Umeda, Takeshi Matsui, Masaki Hata, Atsushi Tamura, Masahiko Itoh, Kosei Takeuchi, Toshihiko Fujimori, Yo-ichi Nabeshima, Tetsuo Noda,[...]. Mol Biol Cell 2008
Tatsuya Katsuno, Kazuaki Umeda, Takeshi Matsui, Masaki Hata, Atsushi Tamura, Masahiko Itoh, Kosei Takeuchi, Toshihiko Fujimori, Yo-ichi Nabeshima, Tetsuo Noda,[...]. Mol Biol Cell 2008
9
ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin.
J Haskins, L Gu, E S Wittchen, J Hibbard, B R Stevenson. J Cell Biol 1998
J Haskins, L Gu, E S Wittchen, J Hibbard, B R Stevenson. J Cell Biol 1998
9
Tight junctions: from simple barriers to multifunctional molecular gates.
Ceniz Zihni, Clare Mills, Karl Matter, Maria S Balda. Nat Rev Mol Cell Biol 2016
Ceniz Zihni, Clare Mills, Karl Matter, Maria S Balda. Nat Rev Mol Cell Biol 2016
9
Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice.
Takehiro Nitta, Masaki Hata, Shimpei Gotoh, Yoshiteru Seo, Hiroyuki Sasaki, Nobuo Hashimoto, Mikio Furuse, Shoichiro Tsukita. J Cell Biol 2003
Takehiro Nitta, Masaki Hata, Shimpei Gotoh, Yoshiteru Seo, Hiroyuki Sasaki, Nobuo Hashimoto, Mikio Furuse, Shoichiro Tsukita. J Cell Biol 2003
9
Tyrosine phosphorylation and dissociation of occludin-ZO-1 and E-cadherin-beta-catenin complexes from the cytoskeleton by oxidative stress.
Radhakrishna K Rao, Shyamali Basuroy, Vijay U Rao, Karl J Karnaky, Akshay Gupta. Biochem J 2002
Radhakrishna K Rao, Shyamali Basuroy, Vijay U Rao, Karl J Karnaky, Akshay Gupta. Biochem J 2002
9
Claudins and the modulation of tight junction permeability.
Dorothee Günzel, Alan S L Yu. Physiol Rev 2013
Dorothee Günzel, Alan S L Yu. Physiol Rev 2013
9
Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells.
Junichi Ikenouchi, Mikio Furuse, Kyoko Furuse, Hiroyuki Sasaki, Sachiko Tsukita, Shoichiro Tsukita. J Cell Biol 2005
Junichi Ikenouchi, Mikio Furuse, Kyoko Furuse, Hiroyuki Sasaki, Sachiko Tsukita, Shoichiro Tsukita. J Cell Biol 2005
9
ZO-1 stabilizes the tight junction solute barrier through coupling to the perijunctional cytoskeleton.
Christina M Van Itallie, Alan S Fanning, Arlene Bridges, James M Anderson. Mol Biol Cell 2009
Christina M Van Itallie, Alan S Fanning, Arlene Bridges, James M Anderson. Mol Biol Cell 2009
8
The tight junction protein complex undergoes rapid and continuous molecular remodeling at steady state.
Le Shen, Christopher R Weber, Jerrold R Turner. J Cell Biol 2008
Le Shen, Christopher R Weber, Jerrold R Turner. J Cell Biol 2008
8
Zonula occludens-1 and -2 are cytosolic scaffolds that regulate the assembly of cellular junctions.
Alan S Fanning, James M Anderson. Ann N Y Acad Sci 2009
Alan S Fanning, James M Anderson. Ann N Y Acad Sci 2009
8
Phosphorylation of Tyr-398 and Tyr-402 in occludin prevents its interaction with ZO-1 and destabilizes its assembly at the tight junctions.
Bertha C Elias, Takuya Suzuki, Ankur Seth, Francesco Giorgianni, Gautam Kale, Le Shen, Jerrold R Turner, Anjaparavanda Naren, Dominic M Desiderio, Radhakrishna Rao. J Biol Chem 2009
Bertha C Elias, Takuya Suzuki, Ankur Seth, Francesco Giorgianni, Gautam Kale, Le Shen, Jerrold R Turner, Anjaparavanda Naren, Dominic M Desiderio, Radhakrishna Rao. J Biol Chem 2009
8
Occludin: structure, function and regulation.
Gemma J Feldman, James M Mullin, Michael P Ryan. Adv Drug Deliv Rev 2005
Gemma J Feldman, James M Mullin, Michael P Ryan. Adv Drug Deliv Rev 2005
8
PKC eta regulates occludin phosphorylation and epithelial tight junction integrity.
Takuya Suzuki, Bertha C Elias, Ankur Seth, Le Shen, Jerrold R Turner, Francesco Giorgianni, Dominic Desiderio, Ramareddy Guntaka, Radhakrishna Rao. Proc Natl Acad Sci U S A 2009
Takuya Suzuki, Bertha C Elias, Ankur Seth, Le Shen, Jerrold R Turner, Francesco Giorgianni, Dominic Desiderio, Ramareddy Guntaka, Radhakrishna Rao. Proc Natl Acad Sci U S A 2009
8
ZO-1 controls endothelial adherens junctions, cell-cell tension, angiogenesis, and barrier formation.
Olga Tornavaca, Minghao Chia, Neil Dufton, Lourdes Osuna Almagro, Daniel E Conway, Anna M Randi, Martin A Schwartz, Karl Matter, Maria S Balda. J Cell Biol 2015
Olga Tornavaca, Minghao Chia, Neil Dufton, Lourdes Osuna Almagro, Daniel E Conway, Anna M Randi, Martin A Schwartz, Karl Matter, Maria S Balda. J Cell Biol 2015
8
Crosstalk of tight junction components with signaling pathways.
Lorenza González-Mariscal, Rocio Tapia, David Chamorro. Biochim Biophys Acta 2008
Lorenza González-Mariscal, Rocio Tapia, David Chamorro. Biochim Biophys Acta 2008
8
Astrocyte-endothelial interactions at the blood-brain barrier.
N Joan Abbott, Lars Rönnbäck, Elisabeth Hansson. Nat Rev Neurosci 2006
N Joan Abbott, Lars Rönnbäck, Elisabeth Hansson. Nat Rev Neurosci 2006
8
Claudins and epithelial paracellular transport.
Christina M Van Itallie, James M Anderson. Annu Rev Physiol 2006
Christina M Van Itallie, James M Anderson. Annu Rev Physiol 2006
7
Isolation and functional characterization of the actin binding region in the tight junction protein ZO-1.
Alan S Fanning, Thomas Y Ma, James Melvin Anderson. FASEB J 2002
Alan S Fanning, Thomas Y Ma, James Melvin Anderson. FASEB J 2002
7
The tight junction protein ZO-1 and an interacting transcription factor regulate ErbB-2 expression.
M S Balda, K Matter. EMBO J 2000
M S Balda, K Matter. EMBO J 2000
7
Tricellulin forms a barrier to macromolecules in tricellular tight junctions without affecting ion permeability.
Susanne M Krug, Salah Amasheh, Jan F Richter, Susanne Milatz, Dorothee Günzel, Julie K Westphal, Otmar Huber, Jörg D Schulzke, Michael Fromm. Mol Biol Cell 2009
Susanne M Krug, Salah Amasheh, Jan F Richter, Susanne Milatz, Dorothee Günzel, Julie K Westphal, Otmar Huber, Jörg D Schulzke, Michael Fromm. Mol Biol Cell 2009
7
Intestinal mucosal barrier function in health and disease.
Jerrold R Turner. Nat Rev Immunol 2009
Jerrold R Turner. Nat Rev Immunol 2009
7
Possible involvement of phosphorylation of occludin in tight junction formation.
A Sakakibara, M Furuse, M Saitou, Y Ando-Akatsuka, S Tsukita. J Cell Biol 1997
A Sakakibara, M Furuse, M Saitou, Y Ando-Akatsuka, S Tsukita. J Cell Biol 1997
7
The ZO-1-associated Y-box factor ZONAB regulates epithelial cell proliferation and cell density.
Maria S Balda, Michelle D Garrett, Karl Matter. J Cell Biol 2003
Maria S Balda, Michelle D Garrett, Karl Matter. J Cell Biol 2003
7
Intestinal permeability regulation by tight junction: implication on inflammatory bowel diseases.
Sung Hee Lee. Intest Res 2015
Sung Hee Lee. Intest Res 2015
7
Pericytes regulate the blood-brain barrier.
Annika Armulik, Guillem Genové, Maarja Mäe, Maya H Nisancioglu, Elisabet Wallgard, Colin Niaudet, Liqun He, Jenny Norlin, Per Lindblom, Karin Strittmatter,[...]. Nature 2010
Annika Armulik, Guillem Genové, Maarja Mäe, Maya H Nisancioglu, Elisabet Wallgard, Colin Niaudet, Liqun He, Jenny Norlin, Per Lindblom, Karin Strittmatter,[...]. Nature 2010
7
Epithelial barrier assembly requires coordinated activity of multiple domains of the tight junction protein ZO-1.
Laurel S Rodgers, M Tanner Beam, James M Anderson, Alan S Fanning. J Cell Sci 2013
Laurel S Rodgers, M Tanner Beam, James M Anderson, Alan S Fanning. J Cell Sci 2013
6
Occludin is required for cytokine-induced regulation of tight junction barriers.
Christina M Van Itallie, Alan S Fanning, Jennifer Holmes, James M Anderson. J Cell Sci 2010
Christina M Van Itallie, Alan S Fanning, Jennifer Holmes, James M Anderson. J Cell Sci 2010
6
Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo.
Amanda M Marchiando, Le Shen, W Vallen Graham, Christopher R Weber, Brad T Schwarz, Jotham R Austin, David R Raleigh, Yanfang Guan, Alastair J M Watson, Marshall H Montrose,[...]. J Cell Biol 2010
Amanda M Marchiando, Le Shen, W Vallen Graham, Christopher R Weber, Brad T Schwarz, Jotham R Austin, David R Raleigh, Yanfang Guan, Alastair J M Watson, Marshall H Montrose,[...]. J Cell Biol 2010
6
Zonula occludens-1 and -2 regulate apical cell structure and the zonula adherens cytoskeleton in polarized epithelia.
Alan S Fanning, Christina M Van Itallie, James M Anderson. Mol Biol Cell 2012
Alan S Fanning, Christina M Van Itallie, James M Anderson. Mol Biol Cell 2012
6
Occludin OCEL-domain interactions are required for maintenance and regulation of the tight junction barrier to macromolecular flux.
Mary M Buschmann, Le Shen, Harsha Rajapakse, David R Raleigh, Yitang Wang, Yingmin Wang, Amulya Lingaraju, Juanmin Zha, Elliot Abbott, Erin M McAuley,[...]. Mol Biol Cell 2013
Mary M Buschmann, Le Shen, Harsha Rajapakse, David R Raleigh, Yitang Wang, Yingmin Wang, Amulya Lingaraju, Juanmin Zha, Elliot Abbott, Erin M McAuley,[...]. Mol Biol Cell 2013
6
Zonula occludens-1 function in the assembly of tight junctions in Madin-Darby canine kidney epithelial cells.
Elizabeth McNeil, Christopher T Capaldo, Ian G Macara. Mol Biol Cell 2006
Elizabeth McNeil, Christopher T Capaldo, Ian G Macara. Mol Biol Cell 2006
6
Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease.
S Zeissig, N Bürgel, D Günzel, J Richter, J Mankertz, U Wahnschaffe, A J Kroesen, M Zeitz, M Fromm, J-D Schulzke. Gut 2007
S Zeissig, N Bürgel, D Günzel, J Richter, J Mankertz, U Wahnschaffe, A J Kroesen, M Zeitz, M Fromm, J-D Schulzke. Gut 2007
6
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