A citation-based method for searching scientific literature

B C Varnum, C Young, G Elliott, A Garcia, T D Bartley, Y W Fridell, R W Hunt, G Trail, C Clogston, R J Toso. Nature 1995
Times Cited: 394







List of co-cited articles
909 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases.
T N Stitt, G Conn, M Gore, C Lai, J Bruno, C Radziejewski, K Mattsson, J Fisher, D R Gies, P F Jones. Cell 1995
589
48

The TAM family: phosphatidylserine sensing receptor tyrosine kinases gone awry in cancer.
Douglas K Graham, Deborah DeRyckere, Kurtis D Davies, H Shelton Earp. Nat Rev Cancer 2014
413
34

R428, a selective small molecule inhibitor of Axl kinase, blocks tumor spread and prolongs survival in models of metastatic breast cancer.
Sacha J Holland, Alison Pan, Christian Franci, Yuanming Hu, Betty Chang, Weiqun Li, Matt Duan, Allan Torneros, Jiaxin Yu, Thilo J Heckrodt,[...]. Cancer Res 2010
360
32



TAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer.
Rachel M A Linger, Amy K Keating, H Shelton Earp, Douglas K Graham. Adv Cancer Res 2008
492
28

Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival.
Christine Gjerdrum, Crina Tiron, Torill Høiby, Ingunn Stefansson, Hallvard Haugen, Tone Sandal, Karin Collett, Shan Li, Emmet McCormack, Bjørn Tore Gjertsen,[...]. Proc Natl Acad Sci U S A 2010
409
26

axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase.
J P O'Bryan, R A Frye, P C Cogswell, A Neubauer, B Kitch, C Prokop, R Espinosa, M M Le Beau, H S Earp, E T Liu. Mol Cell Biol 1991
627
26

Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer.
Zhenfeng Zhang, Jae Cheol Lee, Luping Lin, Victor Olivas, Valerie Au, Thomas LaFramboise, Mohamed Abdel-Rahman, Xiaoqi Wang, Alan D Levine, Jin Kyung Rho,[...]. Nat Genet 2012
867
25

Immunobiology of the TAM receptors.
Greg Lemke, Carla V Rothlin. Nat Rev Immunol 2008
569
24

TAM receptors are pleiotropic inhibitors of the innate immune response.
Carla V Rothlin, Sourav Ghosh, Elina I Zuniga, Michael B A Oldstone, Greg Lemke. Cell 2007
705
24

The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells.
Magdalena Paolino, Axel Choidas, Stephanie Wallner, Blanka Pranjic, Iris Uribesalgo, Stefanie Loeser, Amanda M Jamieson, Wallace Y Langdon, Fumiyo Ikeda, Juan Pablo Fededa,[...]. Nature 2014
291
24


An anti-Axl monoclonal antibody attenuates xenograft tumor growth and enhances the effect of multiple anticancer therapies.
X Ye, Y Li, S Stawicki, S Couto, J Eastham-Anderson, D Kallop, R Weimer, Y Wu, L Pei. Oncogene 2010
161
21

Structural basis for Gas6-Axl signalling.
Takako Sasaki, Pjotr G Knyazev, Naomi J Clout, Yuri Cheburkin, Walter Göhring, Axel Ullrich, Rupert Timpl, Erhard Hohenester. EMBO J 2006
179
21

Biology of the TAM receptors.
Greg Lemke. Cold Spring Harb Perspect Biol 2013
342
19

Gas6 induces proliferation in prostate carcinoma cell lines expressing the Axl receptor.
Pier Paolo Sainaghi, Luigi Castello, Luca Bergamasco, Margherita Galletti, Paola Bellosta, Gian Carlo Avanzi. J Cell Physiol 2005
161
18

Phagocytosis and clearance of apoptotic cells is mediated by MER.
R S Scott, E J McMahon, S M Pop, E A Reap, R Caricchio, P L Cohen, H S Earp, G K Matsushima. Nature 2001
864
18

Axl as a potential therapeutic target in cancer: role of Axl in tumor growth, metastasis and angiogenesis.
Y Li, X Ye, C Tan, J-A Hongo, J Zha, J Liu, D Kallop, M J C Ludlam, L Pei. Oncogene 2009
208
18

Differential TAM receptor-ligand-phospholipid interactions delimit differential TAM bioactivities.
Erin D Lew, Jennifer Oh, Patrick G Burrola, Irit Lax, Anna Zagórska, Paqui G Través, Joseph Schlessinger, Greg Lemke. Elife 2014
165
18


Receptor tyrosine kinase AXL is induced by chemotherapy drugs and overexpression of AXL confers drug resistance in acute myeloid leukemia.
Chih-Chen Hong, Jong-Ding Lay, Jhy-Shrian Huang, Ann-Lii Cheng, Jih-Luh Tang, Ming-Tseh Lin, Gi-Ming Lai, Shuang-En Chuang. Cancer Lett 2008
152
17

Novel mechanism of lapatinib resistance in HER2-positive breast tumor cells: activation of AXL.
Li Liu, James Greger, Hong Shi, Yuan Liu, Joel Greshock, Roland Annan, Wendy Halsey, Ganesh M Sathe, Anne-Marie Martin, Tona M Gilmer. Cancer Res 2009
350
17

AXL is a potential target for therapeutic intervention in breast cancer progression.
Yi-Xiang Zhang, Peter G Knyazev, Yuri V Cheburkin, Kirti Sharma, Yuri P Knyazev, László Orfi, István Szabadkai, Henrik Daub, György Kéri, Axel Ullrich. Cancer Res 2008
158
17

An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance.
Lauren Averett Byers, Lixia Diao, Jing Wang, Pierre Saintigny, Luc Girard, Michael Peyton, Li Shen, Youhong Fan, Uma Giri, Praveen K Tumula,[...]. Clin Cancer Res 2013
675
17

Receptor tyrosine kinases, TYRO3, AXL, and MER, demonstrate distinct patterns and complex regulation of ligand-induced activation.
Wen-I Tsou, Khanh-Quynh N Nguyen, Daniel A Calarese, Scott J Garforth, Anita L Antes, Sergey V Smirnov, Steve C Almo, Raymond B Birge, Sergei V Kotenko. J Biol Chem 2014
145
17

AXL Inhibitors in Cancer: A Medicinal Chemistry Perspective.
Samuel H Myers, Valerie G Brunton, Asier Unciti-Broceta. J Med Chem 2016
122
17

Dominant-negative inhibition of the Axl receptor tyrosine kinase suppresses brain tumor cell growth and invasion and prolongs survival.
Peter Vajkoczy, Pjotr Knyazev, Andrea Kunkel, Hans-Holger Capelle, Sandra Behrndt, Hendrik von Tengg-Kobligk, Fabian Kiessling, Uta Eichelsbacher, Marco Essig, Tracy-Ann Read,[...]. Proc Natl Acad Sci U S A 2006
192
16

The Axl receptor tyrosine kinase confers an adverse prognostic influence in pancreatic cancer and represents a new therapeutic target.
Jan-Bart M Koorstra, Collins A Karikari, Georg Feldmann, Savita Bisht, Pamela Leal Rojas, G Johan A Offerhaus, Hector Alvarez, Anirban Maitra. Cancer Biol Ther 2009
140
16

Intracellular signaling of the Ufo/Axl receptor tyrosine kinase is mediated mainly by a multi-substrate docking-site.
J Braunger, L Schleithoff, A S Schulz, H Kessler, R Lammers, A Ullrich, C R Bartram, J W Janssen. Oncogene 1997
126
16

Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET.
Erinn B Rankin, Katherine C Fuh, Laura Castellini, Kartik Viswanathan, Elizabeth C Finger, Anh N Diep, Edward L LaGory, Mihalis S Kariolis, Andy Chan, David Lindgren,[...]. Proc Natl Acad Sci U S A 2014
179
16

Axl and growth arrest-specific gene 6 are frequently overexpressed in human gliomas and predict poor prognosis in patients with glioblastoma multiforme.
Markus Hutterer, Pjotr Knyazev, Ariane Abate, Markus Reschke, Hans Maier, Nadia Stefanova, Tatjana Knyazeva, Verena Barbieri, Markus Reindl, Armin Muigg,[...]. Clin Cancer Res 2008
202
15

Expression of axl in lung adenocarcinoma and correlation with tumor progression.
Yi-Shing Shieh, Chiung-Ya Lai, Yu-Rung Kao, Shine-Gwo Shiah, Yi-Wen Chu, Herng-Sheng Lee, Cheng-Wen Wu. Neoplasia 2005
198
15

Cloning and mRNA expression analysis of a novel human protooncogene, c-mer.
D K Graham, T L Dawson, D L Mullaney, H R Snodgrass, H S Earp. Cell Growth Differ 1994
262
15

Genes specifically expressed at growth arrest of mammalian cells.
C Schneider, R M King, L Philipson. Cell 1988
855
15


AXL induces epithelial-to-mesenchymal transition and regulates the function of breast cancer stem cells.
M K Asiedu, F D Beauchamp-Perez, J N Ingle, M D Behrens, D C Radisky, K L Knutson. Oncogene 2014
189
15

AXL is an essential factor and therapeutic target for metastatic ovarian cancer.
Erinn B Rankin, Katherine C Fuh, Tiffany E Taylor, Adam J Krieg, Margaret Musser, Jenny Yuan, Kevin Wei, Calvin J Kuo, Teri A Longacre, Amato J Giaccia. Cancer Res 2010
158
14

A novel tyrosine kinase switch is a mechanism of imatinib resistance in gastrointestinal stromal tumors.
D Mahadevan, L Cooke, C Riley, R Swart, B Simons, K Della Croce, L Wisner, M Iorio, K Shakalya, H Garewal,[...]. Oncogene 2007
213
14

MET and AXL inhibitor NPS-1034 exerts efficacy against lung cancer cells resistant to EGFR kinase inhibitors because of MET or AXL activation.
Jin Kyung Rho, Yun Jung Choi, Seon Ye Kim, Tae Won Kim, Eun Kyung Choi, Seon-Joo Yoon, Bu Man Park, Eunhye Park, Jong Hwan Bae, Chang-Min Choi,[...]. Cancer Res 2014
104
14

An engineered Axl 'decoy receptor' effectively silences the Gas6-Axl signaling axis.
Mihalis S Kariolis, Yu Rebecca Miao, Douglas S Jones, Shiven Kapur, Irimpan I Mathews, Amato J Giaccia, Jennifer R Cochran. Nat Chem Biol 2014
93
15

Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis.
A Angelillo-Scherrer, P de Frutos, C Aparicio, E Melis, P Savi, F Lupu, J Arnout, M Dewerchin, M Hoylaerts, J Herbert,[...]. Nat Med 2001
333
13


Targeting Axl and Mer kinases in cancer.
Anupam Verma, Steven L Warner, Hariprasad Vankayalapati, David J Bearss, Sunil Sharma. Mol Cancer Ther 2011
175
13

Tyro-3 family receptors are essential regulators of mammalian spermatogenesis.
Q Lu, M Gore, Q Zhang, T Camenisch, S Boast, F Casagranda, C Lai, M K Skinner, R Klein, G K Matsushima,[...]. Nature 1999
376
13

Axl mediates acquired resistance of head and neck cancer cells to the epidermal growth factor receptor inhibitor erlotinib.
Keith M Giles, Felicity C Kalinowski, Patrick A Candy, Michael R Epis, Priscilla M Zhang, Andrew D Redfern, Lisa M Stuart, Gregory J Goodall, Peter J Leedman. Mol Cancer Ther 2013
116
13

AXL inhibition sensitizes mesenchymal cancer cells to antimitotic drugs.
Catherine Wilson, Xiaofen Ye, Thinh Pham, Eva Lin, Sara Chan, Erin McNamara, Richard M Neve, Lisa Belmont, Hartmut Koeppen, Robert L Yauch,[...]. Cancer Res 2014
100
13

AXL mediates resistance to cetuximab therapy.
Toni M Brand, Mari Iida, Andrew P Stein, Kelsey L Corrigan, Cara M Braverman, Neha Luthar, Mahmoud Toulany, Parkash S Gill, Ravi Salgia, Randall J Kimple,[...]. Cancer Res 2014
132
13

Axl as a mediator of cellular growth and survival.
Haley Axelrod, Kenneth J Pienta. Oncotarget 2014
117
13

TAM receptors, Gas6, and protein S: roles in inflammation and hemostasis.
Jonathan H M van der Meer, Tom van der Poll, Cornelis van 't Veer. Blood 2014
180
13


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.